Stability of Supply Coefficients and Consistency of Supply-Driven and Demand-Driven Input-Output Models: A Reply

1991 ◽  
Vol 23 (12) ◽  
pp. 1811-1817 ◽  
Author(s):  
S Deman
Keyword(s):  
Real World ◽  
Joint Stability ◽  
Input Output ◽  
Aggregated Data ◽  
The Real ◽  
Us Economy ◽  
The Us ◽  
The Usa ◽  
Stability And Consistency

A comment by Miller was published in the August 1989 issue of Environment and Planning A, which makes an intriguing comparison of a paper by Chen and Rose with one by myself. His comment concerns the uses of various terminologies in the literature on supply-driven and demand-driven input—output models and the claims to have defined terms such as ‘stability’, ‘joint stability’, and ‘consistency’. Further, generalizations are made on the basis of a specific set of aggregated data for the US economy to show that biproportional changes suggested in my theorem are unlikely to be observed in the real world. I will show that Miller adds no illumination to the issues of ‘stability’ or ‘consistency’, and that, in fact, his comment accomplishes nothing of import. His comment could also leave us with the impression that the USA is the only ‘real-world’ example worthy of comment.

scholarly journals Exploring the Real-World Profile of Refractory and Non-Refractory Chronic Idiopathic Urticaria Patients in the US

2016 ◽  
Vol 137 (2) ◽  
pp. AB242
Author(s):  
Susan Gabriel ◽  
Meryl Mendelson ◽  
Alexander J. Gillespie ◽  
Ben Hoskin
Keyword(s):  
Real World ◽  
Chronic Idiopathic Urticaria ◽  
The Real ◽  
The Us

Macroeconomic conditions are only an illusion, not the solution, to firm sustainability: unveiling the new dimension of stakeholder well-being

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Zahid Irshad Younas ◽  
Mahvesh Khan ◽  
Mamdouh Abdulaziz Saleh Al-Faryan
Keyword(s):  
Well Being ◽  
Developed Countries ◽  
Macroeconomic Performance ◽  
Content Type ◽  
Macroeconomic Conditions ◽  
Us Economy ◽  
The Us ◽  
The Usa ◽  
Negative Impacts ◽  
The One

Purpose The purpose of the study is to explore the misconception that in developed countries, macroeconomic performance lead to sustainable firms or improves stakeholder well-being. The results may be the opposite or even worse. Design/methodology/approach This study examined this misconception using balanced panel data from 1,122 firms from different sectors of the US economy and data on macroeconomic performance from the World Bank. Findings The results of the one-step generalised method of moments indicate that most macroeconomic performance indicators had significant and negative impacts on firm sustainability and stakeholder well-being. Practical implications From a societal perspective, the results illustrate that the fruits of macroeconomic performance of the US economy do not reach stakeholders through firms’ sustainability. Thus, linking the economy’s macroeconomic performance with firm sustainability is vital for sustainably uplifting society and for stakeholder well-being. Originality/value From a policy perspective, this study reveals that the greater focus on macroeconomic performance in the USA over the past decades has resulted in lower firm sustainability because of the malfunctioning of social, economic, environmental and governance factors. This has negatively influenced stakeholder well-being in the country.

Cabozantinib versus other TKIs after CPI treatment in the real-world management of patients with metastatic renal cell carcinoma (mRCC).

2021 ◽  
Vol 39 (6_suppl) ◽  
pp. 293-293
Author(s):  
Florence Marteau ◽  
Brooke Harrow ◽  
Christine McCarthy ◽  
Joel Wallace ◽  
Alisha Monnette ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Real World ◽  
Renal Cell ◽  
Response Rate ◽  
Checkpoint Inhibitors ◽  
P Value ◽  
The Real ◽  
The Us

293 Background: Checkpoint inhibitors (CPIs) are a treatment option for patients with metastatic renal cell carcinoma (mRCC), but there is limited clinical data on the efficacy of targeted therapies following CPI treatment. Cabozantinib is a tyrosine kinase inhibitor (TKI) that targets multiple receptor kinases implicated in tumorigenesis. In the US, cabozantinib is approved for use in patients with advanced RCC including after CPI treatment. Methods: This retrospective observational cohort study (NCT04353765) evaluated outcomes associated with cabozantinib or other TKIs (axitinib, lenvatinib, pazopanib, sorafenib, sunitinib) in patients with mRCC following CPI treatment. Eligible patients initiated TKI therapy between May 1, 2016 and Sep 31, 2019 and had received a CPI as their last systemic treatment prior to TKI therapy. Patients were identified from the US Oncology Network iKnowMed electronic health record database through structured queries and a targeted chart review. The following real-world outcomes were assessed: 6-month response rate (RR6months; primary); overall response rate (ORR); overall survival (OS); time to treatment discontinuation (TTD); rates of dose reductions, and discontinuation due to adverse events (AEs). The p value for RR6months was used to test for non-inferiority. Results: Eligible patients ( n = 247) had a mean (SD) age of 65.9 (10.5) years and 74.1% were male; 75.7% ( n = 187) received cabozantinib and 24.3% ( n = 60) received other TKIs. All patients had intermediate or poor MSKCC score; more poor-risk patients received cabozantinib than other TKIs (28.9% vs 20%). Outcomes data are shown in the Table. Compared with other TKIs, cabozantinib was associated with a significantly higher RR6months and ORR, and TTD was twice as long with cabozantinib. Discontinuation due to AEs was more frequent with other TKIs than with cabozantinib, although this was not statistically significant; 21.7% of discontinuations occurred during the first 3 months of treatment. AEs leading to discontinuation were consistent with the known safety profile of the products. Conclusions: In this mRCC population receiving routine care in the US, cabozantinib was used more frequently than other TKIs after CPI treatment. Cabozantinib was an effective and well tolerated option post-CPI, with a high response rate in the real-world setting.abozantinib was associated with a significantly higher response rate and a lower discontinuation rate due to AEs; TTD was double that of other TKIs. [Table: see text]

scholarly journals Whitewashing Capitalism: Mainstream Economics’ Resounding Silence on Race and Racism

2019 ◽  
Vol 51 (4) ◽  
pp. 562-571
Author(s):  
Tim Koechlin
Keyword(s):  
Racial Inequality ◽  
Jel Classification ◽  
Economic Science ◽  
Race And Racism ◽  
Mainstream Economics ◽  
Us Economy ◽  
Economic Practices ◽  
The Us ◽  
The Usa ◽  
History Of

This paper is about the gaping silence in mainstream economics regarding the relationship among capitalism, race, racism, and enduring racial inequality in the USA. Racial inequality is a glaring and enduring fact about the US economy. And yet mainstream economics has little to say about race or racism. Gregory Mankiw’s bestselling textbook devotes seven pages to “discrimination.” There is no discussion of racism per se. Mainstream economists and textbooks typically conflate racism and “discrimination,” and reassure the reader that “markets contain a natural remedy for employer discrimination” (Mankiw, 2008: 409). A student is likely to leave ECON 101 (or an economics major) with a sense that “economic science” has “shown” that discrimination is not that big a deal, and that the history of racist plunder and exploitation in the USA (of which there likely has been no discussion) is not relevant to “economics.” I argue here that the mainstream narrative (its assumptions, its logic, its conclusions, and its rhetorical choices and emphases) systematically obscures, dismisses, and ignores essential ways that racial inequality has been (re)produced by US capitalism. Especially striking is the resounding silence about the legacy of racist economic practices—in particular, the ways in which the enormous black/white wealth gap (and its effects) in the USA are linked to centuries of racist exclusion, violence, and plunder. The mainstream narrative thus whitewashes capitalism and exonerates “the market system.” The final section argues for a radical multidisciplinary economics. JEL classification: J15, D63

The Real-World Effectiveness and Safety of Vedolizumab for Moderate–Severe Crohn’s Disease: Results From the US VICTORY Consortium

2016 ◽  
Vol 111 (8) ◽  
pp. 1147-1155 ◽  
Author(s):  
Parambir S Dulai ◽  
Siddharth Singh ◽  
Xiaoqian Jiang ◽  
Farhad Peerani ◽  
Neeraj Narula ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Real World ◽  
The Real ◽  
The Us

Stability of Supply Coefficients and Consistency of Supply-Driven and Demand-Driven Input — Output Models: A Comment

1989 ◽  
Vol 21 (8) ◽  
pp. 1113-1120 ◽  
Author(s):  
R E Miller
Keyword(s):  
Recent Literature ◽  
Supply Side ◽  
Demand Side ◽  
Joint Stability ◽  
Input Output ◽  
Stability And Consistency

Recent literature dealing with supply-side and demand-side Input — Output models appears to contain some confusion or at least imprecision in the use of ‘stability’, ‘joint stability’, and ‘consistency’. This comment contains a tentative proposal for terminological conventions with respect to the three concepts. These thoughts are offered against the backdrop of a recent paper by Deman which illustrates the definitional problems.

scholarly journals Simple Enough Processor : From Scratch Elaborated Simulated Educational CPU

2021 ◽  
Author(s):  
Abdelaziz Kara ◽  
Messaoud Mostefai
Keyword(s):  
Real World ◽  
Control Unit ◽  
Input Output ◽  
The Real ◽  
Flexible Control

This paper describes a new simplistic academic CPU, designed to be constructed step-by-step by the student using a logic simulator called Logisim. An effort is made to close the gap with the real-world processors by supplying their major capabilities, like multiple programmable registers, multiple addressing modes, shift instruction, comparison and logic instructions, multiple branch and jump instructions, the stack and subroutine mechanisms, flags indicators, input/output mechanism, a proper assembler... etc. The processor would comprise 21 instructions and 4 addressing modes, with the capability using the flexible control unit sequencer, to easily add more customizable instructions.<br>

scholarly journals Trends Of Changes In The Polish Industry Innovativeness (Against The Background Of Leading World Economies)

2011 ◽  
Vol 4 (5) ◽  
Author(s):  
Adam Mazurkiewicz ◽  
Rozalia Sitkowska
Keyword(s):  
Venture Capital ◽  
Processing Industry ◽  
Us Economy ◽  
The Us ◽  
The Usa ◽  
Per Capita ◽  
Polish Economy ◽  
Business Financing ◽  
Investment Goods ◽  
The Eu

Tendencies concerning innovativeness changes in selected sectors of the Polish economy were identified in the paper. The trends were depicted against the background of the USA, Japan and the EU-15 and they comprised: public and business financing of the R&D area with reference to GDP, R&D expenditure per capita, and venture capital funds supporting innovations commercialization. The observed correlation between the financing level of the R&D area and the innovativeness level of the US economy made the basis for the analysis conducted. The analysis concentrated on trends occurring in the Polish economy in the context of industry innovativeness, in particular processing industry, including the sector of investment goods. Conclusions resulting from the analysis of innovation commercialization processes with venture capital funds were presented. Countermeasures which were taken in Poland to prevent the marginalization of financing the R&D area were demonstrated as well.

scholarly journals The Impact of COVID-19 on the US Economy: The Multiplier Effects of Tourism

Economies ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 2
Author(s):  
Nikolaos Rodousakis ◽  
George Soklis
Keyword(s):  
Comparative Analysis ◽  
Domestic Product ◽  
Input Output ◽  
Output Data ◽  
Us Economy ◽  
The Us ◽  
Multiplier Effects ◽  
External Sector ◽  
The Impact

This article explores the multiplier effects on domestic product, employment, and the external sector of the US economy due to the decline of tourism activities during the pandemic. For this purpose, we use an input-output model and the latest available input-output data from the Organisation for Economic Co-operation and Development (OECD’s) database. It was found that for every USD million decrease in tourism receipts, the net output decreases about USD 1.53 million, the level of employment decreases about 16.86 persons, imports decrease about USD 0.20 million, while the comparative analysis of these results with the economy’s average multipliers indicates that tourism constitutes a key sector of the US economy. From the evaluation of the results, it is deduced that the decline of tourism activities recorded in the year 2020 accounts for about one-fourth of the observed recession in the US economy.

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