Binuclear complexes of copper(II) and zinc(II) halides with bidentate and quadridentate Schiff base complexes

1968 ◽  
Vol 21 (6) ◽  
pp. 1473 ◽  
Author(s):  
GE Batley ◽  
DP Graddon
Keyword(s):  
Schiff Base ◽  
Copper Complexes ◽  
Solvent Molecule ◽  
Schiff Base Complexes ◽  
Binuclear Complexes ◽  
Phenolic Oxygen ◽  
Near Ultraviolet ◽  
Tetrahedral Environment ◽  
Binuclear Structure ◽  
Solvent Molecules

Binuclear complexes of the types CuB,CuCl2, CuB,ZnCl2, ZnB,ZnCl2, and CuL2,CuCl2 have been obtained where BH2 is a quadridentate Schiff base derived from salicylaldehyde and a polyrnethylenediamine and LH is an N-alkylsalicylaldimine. The stereochemistry of the copper atoms in the binuclear complexes is inferred from comparisons of their reflectance spectra with the spectra of the simple copper complexes CuB and CuL2. The structures of the zinc complexes are discussed by reference to near ultraviolet spectra of the ligands and infrared spectra in the 1500-1560 cm-1 region. The evidence suggests that in the complexes of the type MB,M'Cl2 either but not both metal atoms may approach a tetrahedral environment. The chemistry of the complexes ZnB,ZnCl2 is complicated by the possibility of either or both zinc atoms becoming 5 coordinate by addition of solvent molecules; in some of these complexes the zinc chloride appears to be attached to a solvent molecule in a 5-coordinate Schiff base unit, rather than by bridging through phenolic oxygen atoms. The oomplexes CuL2,CuCl2 apparently have a symmetrical binuclear structure based on a trans arrangement of the Schiff base units rather than an unsymmetrical structure resembling that of the complexes CuB,CuCl2. Complexes of the types CuL2,ZnCl2 and ZnL2,ZnCl2 could not be obtained.

scholarly journals Utilization and simulation of innovative new binuclear Co(ii), Ni(ii), Cu(ii), and Zn(ii) diimine Schiff base complexes in sterilization and coronavirus resistance (Covid-19)

2021 ◽  
Vol 19 (1) ◽  
pp. 772-784
Author(s):  
Moamen S. Refat ◽  
Ahmed Gaber ◽  
Walaa F. Alsanie ◽  
Mohamed I. Kobeasy ◽  
Rozan Zakaria ◽  
...  
Keyword(s):  
Schiff Base ◽  
Molecular Docking ◽  
Metal Ions ◽  
Free Ligand ◽  
Schiff Base Complexes ◽  
Hydroxyl Groups ◽  
Binuclear Complexes ◽  
Central Metal ◽  
H Nmr ◽  
Biological Studies

Abstract This article aimed at the synthesis and molecular docking assessment of new diimine Schiff base ligand, namely 2-((E)-(2-((Z)-2-(4-chlorophenyl)-2-hydroxyvinyl)hydrazono) methyl)-6-methoxyphenol (methoxy-diim), via the condensation of 1-(4-chloro-phenyl)-2-hydrazino-ethenol compound with 2-((E)-(2-((Z)-2-(4-chlorophenyl)-2-hydroxy vinyl) hydrazono)methyl)-6-methoxyphenol in acetic acid as well as the preparation of new binuclear complexes of Co(ii), Ni(ii), Cu(ii), and Zn(ii). The following synthesized complexes were prepared in a ratio of 2:1 (metal/ligand). The 1H-NMR, UV-Vis, and FTIR spectroscopic data; molar conductivity measurements; and microanalytical, XRD, TGA/DTG, and biological studies were carried out to determine the molecular structure of these complexes. According to the spectroscopic analysis, the two central metal ions were coordinated with the diamine ligand via the nitrogen of the hydrazine and oxygen of the hydroxyl groups for the first metal ions and via the nitrogen of the hydrazine and oxygen of the phenol group for the second metal ions. Molecular docking for the free ligand was carried out against the breast cancer 3hb5-oxidoreductase and the 4o1v-protein binding kidney cancer and COVID-19 protease, and good results were obtained.

Copper complexes of polyfunctional phthalazines. Mononuclear and polynuclear derivatives

1982 ◽  
Vol 60 (20) ◽  
pp. 2583-2593 ◽  
Author(s):  
Dorothy V. Bautista ◽  
John C. Dewan ◽  
Laurence K. Thompson
Keyword(s):  
Copper Complexes ◽  
Magnetic Moments ◽  
Magnetic Data ◽  
Binuclear Complexes ◽  
Tetradentate Ligands ◽  
Binuclear Structure ◽  
Neutral Ligands ◽  
Hydroxide Bridge ◽  
Anionic Groups ◽  
Protonated Complexes

Mononuclear, binuclear, and trinuclear copper(II) complexes of the tetradentate ligands 1,4-di(2′-pyridyl) aminophthalazine (PAP) and 1,4-di(4′-methyl-2′-pyridyl) aminophthalazine (PAP4Me) and binuclear complexes of the tetradentate ligand 1,4-di(6′-methyl-2′-pyridyl) aminophthalazine (PAP6Me) are reported. In a series of binuclear carboxylate derivatives carboxylate bridges exist between copper centres in all cases and in some cases oxygen bridges (hydroxide or methoxide) are indicated. In all other polynuclear derivatives hydroxide bridges are anticipated on the basis of analytical, spectral, and magnetic data. The ligands exist as anionic groups in some binuclear carboxylate derivatives while in the other polynuclear systems neutral ligands are found. In reactions in aqueous solution protonated mononuclear derivatives are obtained for both PAP and PAP4Me in cases where solutions of the metal salts are inherently acidic, followed by polynuclear, neutral ligand complexes which form when the pH increases. Mononuclear protonated complexes are not obtained with PAP6Me, where steric factors may prevent the formation of such derivatives. Low magnetic moments (1.1–1.5 BM) are observed for most hydroxy bridged complexes while even lower values ( < 0.70 BM ) are observed for two binuclear complexes of PAP6Me, indicating the possibility of strong antiferromagnetic exchange between metal centres. A preliminary X-ray investigation of the complex [Cu2(PAP4Me)(OH)(NO3)2(H2O)2]NO3 indicates a triple bridged binuclear structure including a bidentate nitrate bridge and a hydroxide bridge with an oxygen bridge angle of 115.2°.

scholarly journals Synthesis and crystal structure of the dinuclear copper(II) Schiff base complex μ-hydroxido-μ-chlorido-bis{[bis(trans-2-nitrocinnamaldehyde)ethylenediamine]chloridocopper(II)} dichloromethane sesquisolvate

2016 ◽  
Vol 72 (3) ◽  
pp. 239-242
Author(s):  
Kazem Barati ◽  
William Clegg ◽  
Mohammad Hossein Habibi ◽  
Ross W. Harrington ◽  
Arash Lalegani ◽  
...  
Keyword(s):  
Schiff Base ◽  
Copper Complexes ◽  
Schiff Base Complex ◽  
Dinuclear Complex ◽  
Molar Ratio ◽  
Schiff Base Ligands ◽  
Synthesis And Crystal Structure ◽  
Trigonal Bipyramidal ◽  
Solvent Molecules ◽  
Hydroxide Bridge

Transition metal complexes of Schiff base ligands have been shown to have particular application in catalysis and magnetism. The chemistry of copper complexes is of interest owing to their importance in biological and industrial processes. The reaction of copper(I) chloride with the bidentate Schiff baseN,N′-bis(trans-2-nitrocinnamaldehyde)ethylenediamine {Nca2en, systematic name: (1E,1′E,2E,2′E)-N,N′-(ethane-1,2-diyl)bis[3-(2-nitrophenyl)prop-2-en-1-imine]} in a 1:1 molar ratio in dichloromethane without exclusion of air or moisture resulted in the formation of the title complex μ-chlorido-μ-hydroxido-bis(chlorido{(1E,1′E,2E,2′E)-N,N′-(ethane-1,2-diyl)bis[3-(2-nitrophenyl)prop-2-en-1-imine]-κ2N,N′}copper(II)) dichloromethane sesquisolvate, [Cu2Cl3(OH)(C20H18N4O4)2]·1.5CH2Cl2. The dinuclear complex has a folded four-membered ring in an unsymmetrical Cu2OCl3core in which the approximate trigonal bipyramidal coordination displays different angular distortions in the equatorial planes of the two CuIIatoms; the chloride bridge is asymmetric, but the hydroxide bridge is symmetric. The chelate rings of the two Nca2en ligands have different conformations, leading to a more marked bowing of one of the ligands compared with the other. This is the first reported dinuclear complex, and the first five-coordinate complex, of the Nca2en Schiff base ligand. Molecules of the dimer are associated in pairs by ring-stacking interactions supported by C—H...Cl interactions with solvent molecules; a further ring-stacking interaction exists between the two Schiff base ligands of each molecule.

scholarly journals The relationship between the strength of hydrogen bonding and spin crossover behaviour in a series of iron(iii) Schiff base complexes

2015 ◽  
Vol 44 (10) ◽  
pp. 4474-4484 ◽  
Author(s):  
Ivan Nemec ◽  
Radovan Herchel ◽  
Zdeněk Trávníček
Keyword(s):  
Hydrogen Bonding ◽  
Schiff Base ◽  
Spin Crossover ◽  
Schiff Base Complexes ◽  
Magnetic Spin ◽  
Solvent Molecules ◽  
The Relationship

The magnetic (spin crossover) properties of the complexes were tuned by the different crystal solvent molecules.

scholarly journals Synthesis, crystal structures and spectroscopic investigation of new Cu/Schiff-base complexes

2014 ◽  
Vol 10 (8) ◽  
pp. 3068-3079
Author(s):  
Ahmed Toumi ◽  
Mohamed Rzaigui ◽  
Hichem Ben Jannet
Keyword(s):  
Schiff Base ◽  
Solid State ◽  
Copper Complexes ◽  
Spectroscopic Properties ◽  
Schiff Base Complexes ◽  
X Ray Diffraction ◽  
Neutral Complex ◽  
Schiff Base Ligands ◽  
1H And 13C Nmr ◽  
Solid State Structures

Three novel Copper complexes, [Cu(L1)2][CuCl2] (1),  [Cu(L2)Cl] (2) and [Cu2(L3)3Cl2] (3), have been prepared by reaction of CuCl with the Schiff-base ligands L1: N,N’-bis(thiophen-2-ylmethylene)-ethane-1,2-diamine, L2: N,N’-bis(1H-pyrrol-2-ylmethylene)ethane-1,2-diamine and L3: N,N’-bis(2-nitrobenzylidene)-ethane-1,2-diamine in acetonitrile. The solid-state structures of these complexes were determined by X-ray diffraction from single crystal data and characterized by 1H and 13C NMR, IR and UV/Vis spectroscopies. This study shows that (1) is an ionic complex with a Cu(I)-centered cation and an isolated linear dichlorocuprate(I) anion, (3) is a dinuclear neutral complex of Cu(I) while (2)  is a mononuclear neutral complex of Cu(II). In the three complexes, Cu is tetracordinated in different geometrical environments. The atomic arrangements and spectroscopic properties of the three complexes are reported. Complexes 1-3 exhibit, in the solid state at room temperature, photoluminescence between 320 and 550 nm.

scholarly journals Studies on Some Hetero Binuclear Copper(II) Schiff base Complexes

2020 ◽  
Vol 36 (05) ◽  
pp. 954-957
Author(s):  
Shivani Prakash ◽  
Anju Kumari Gupta ◽  
Sachin Prakash ◽  
D. Prakash
Keyword(s):  
Magnetic Susceptibility ◽  
Schiff Base ◽  
Condensation Reaction ◽  
Molar Conductance ◽  
Schiff Base Complexes ◽  
Planar Geometry ◽  
Binuclear Complexes ◽  
Binuclear Copper ◽  
Conductance Measurement ◽  
Square Planar

A series of new hetero binuclear complexes of copper(II) and lead(II) using Schiff base have been synthesized. The Schiff base has been derived from the condensation reaction between Salicylaldehyde and 1,2-Ethylenediamine. The hetero binuclear complexes have been characterized by using elemental analysis, molar conductance measurement, magnetic susceptibility studies, UV-Vis and IR spectra. The studies revealed square planar geometry for the complexes with coordination number four.

scholarly journals Antimicrobial and antibiofilm activities of Cu(II) Schiff base complexes against methicillin-susceptible and resistant Staphylococcus aureus

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Pooi Yin Chung ◽  
Ranon Earn Yueh Khoo ◽  
Hui Shan Liew ◽  
May Lee Low
Keyword(s):  
Staphylococcus Aureus ◽  
Schiff Base ◽  
Cell Line ◽  
Copper Complexes ◽  
Methicillin Resistance ◽  
Schiff Base Complexes ◽  
Normal Lung ◽  
Antibiofilm Activity ◽  
Drug Of Choice ◽  
The Individual

Abstract Background Methicillin-resistance S. aureus (MRSA) possesses the ability to resist multiple antibiotics and form biofilm. Currently, vancomycin remains the last drug of choice for treatment of MRSA infection. The emergence of vancomycin-resistant S. aureus (VRSA) has necessitated the development of new therapeutic agents against MRSA. In this study, the antimicrobial and antibiofilm activities of two copper-complexes derived from Schiff base (SBDs) were tested individually, and in combination with oxacillin (OXA) and vancomycin (VAN) against reference strains methicillin-susceptible and methicillin-resistant Staphylococcus aureus. The toxicity of the SBDs was also evaluated on a non-cancerous mammalian cell line. Methods The antimicrobial activity was tested against the planktonic S. aureus cells using the microdilution broth assay, while the antibiofilm activity were evaluated using the crystal violet and resazurin assays. The cytotoxicity of the SBDs was assessed on MRC5 (normal lung tissue), using the MTT assay. Results The individual SBDs showed significant reduction of biomass and metabolic activity in both S. aureus strains. Combinations of the SBDs with OXA and VAN were mainly additive against the planktonic cells and cells in the biofilm. Both the compounds showed moderate toxicity against the MRC5 cell line. The selectivity index suggested that the compounds were more cytotoxic to S. aureus than the normal cells. Conclusion Both the SBD compounds demonstrated promising antimicrobial and antibiofilm activities and have the potential to be further developed as an antimicrobial agent against infections caused by MRSA.

Studying Media Polarity Effects on the Photo-Physical Behaviors of Organometallic Complexes with Azo-Containing Schiff-Base Ligands

2018 ◽  
Vol 232 (12) ◽  
pp. 1807-1825 ◽  
Author(s):  
Mahsa Khadem Sadigh ◽  
Majid Hasani ◽  
Jinous Rahimpour
Keyword(s):  
Schiff Base ◽  
Copper Complexes ◽  
Dipole Moments ◽  
Organometallic Complexes ◽  
Physical Behavior ◽  
Biological Phenomena ◽  
Energy Relationships ◽  
Quantitative Results ◽  
Solvent Molecules ◽  
Polarity Effects

Abstract Solvent molecules as an important factor can modify the photo-physical behavior of organometallic complexes. For precise investigation, in this paper, the spectral behavior of some groups of copper complexes with different substituents were studied in various solvent media. In this case, the linear solvation energy relationships concept was used for determination of various contribution of media induced specific and non-specific interactions on the photo-physical behavior of various forms of organometallic complexes with azo-containing Schiff-base dyes. Moreover, the calculated dipole moments indicate that samples with different forms tend to have polar structure in the excited state as compared to those in the ground state. By exploiting of calculated dipole moments and obtained quantitative results in the ground and excited states, the dominant solvent induced resonance structures were also estimated. The obtained experimental results can give more information about how these samples can behave in various physical, chemical and biological phenomena.

scholarly journals Crystal structures and magnetic properties of two series of phenoxo-O bridged dinuclear Ln2 (Ln = Gd, Tb, Dy) complexes

2017 ◽  
Vol 46 (46) ◽  
pp. 16294-16305 ◽  
Author(s):  
Marek Machata ◽  
Radovan Herchel ◽  
Ivan Nemec ◽  
Zdeněk Trávníček
Keyword(s):  
Magnetic Properties ◽  
Schiff Base ◽  
Crystal Structures ◽  
Molecular Structures ◽  
Schiff Base Complexes ◽  
Solvent Molecules

Different solvent molecules as ligands in the molecular structures of the dinuclear Ln(iii) Schiff base complexes (Ln = Gd, Tb, and Dy) influenced the magnetic properties of the Dy(iii) derivatives.

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