95 THE USE OF A REARING-FASTING PROGRAM AS AN ALTERNATIVE BIO-STIMULATION METHOD TO HORMONAL EQUINE CHORIONIC GONADOTROPIN TREATMENT TO CONTROL THE EMBRYO RECOVERY OF RABBIT FEMALES

2017 ◽  
Vol 29 (1) ◽  
pp. 155
Author(s):  
G. M. K. Mehaisen ◽  
A. O. Abbas
Keyword(s):  
Zealand White Rabbit ◽  
Sexual Receptivity ◽  
Control Group ◽  
Corpora Lutea ◽  
Control Groups ◽  
Chi Square ◽  
Embryo Recovery ◽  
Stimulation Method ◽  
Ad Libitum ◽  
And Control

The aim of this study was to investigate the effect of a rearing-fasting program as an alternative bio-stimulation method to hormonal eCG treatments on the embryo recovery of rabbit females. A total number of 119 nulliparous New Zealand White rabbit females at 14 wk old were randomly allocated into 1 of the following 3 groups before the first insemination at 18 weeks old: control group (n = 39), females were fed ad libitum until the first insemination; eCG group (n = 34), females were fed ad libitum and treated with 50 IU of eCG hormone SC 60 h before the first insemination; and r-FP group (n = 46), females were fasted 3 days per week during 3 wk and then allowed to feed ad libitum 1 wk before the first insemination. Sexual receptivity was evaluated for each group on the day of insemination. Only receptive females (74/119) were artificially inseminated and immediately were induced for ovulation by intramuscular injection with gonadotropin-releasing hormone analogue (0.8 μg of buserelin acetate). In 23 receptive females, embryos were recovered postmortem at 72 h post-insemination in each group (n = 7, 9, and 7 in control, eCG, and r-FP groups, respectively). The number of recent corpora lutea on both ovaries (CL), the number of hemorrhagic follicles (HF), the recovery rate (RR), the number of normal embryos recovered in receptive females (NE), the embryo donor rate (DR), and the blastocyst rate (BR) were recorded for all groups. A General Linear Model was performed to analyse CL, HF, and NE, and a chi-square test was used to compare sexual receptivity, RR, DR, and BR in the experimental groups (eCG, r-FP, and control). A significant increase in sexual receptivity was observed in eCG group compared with the other groups (82 v. 50 and 59%; eCG v. r-FP and control groups, respectively; P < 0.05). The CL was significantly (P < 0.05) higher in eCG group (13.8) than in r-FP and control groups (9.1 and 10.3, respectively). However, high incidence of HF was also observed in the eCG group (3.9 v. 0.9 and 1.3 in eCG v. r-FP and control, respectively; P < 0.05). The RR was significantly (P < 0.05) higher in r-FP group (64.1%) when compared with eCG and control groups (38.7 and 20.8%, respectively). The DR was significantly higher for r-FP group compared with the control (100% v. 42.9%, respectively; P < 0.05) and intermediate for eCG group (77.8%). No significant differences were observed in the NE (6.1, 5.7, and 5.0 in eCG, r-FP, and control, respectively). The BR significantly (P < 0.05) decreased in eCG group when compared with r-FP or control groups (4.7% v. 60.0 or 53.3%, respectively). Our results indicated that a rearing-fasting program followed by 1 wk of feed flushing before the first insemination of nulliparous rabbit females could be recommended as an efficient bio-stimulation method to control embryo recovery. However, these results need to be confirmed in a larger scale and several reproductive cycles before widely applied.

Seroprevalence of Helicobacter pylori infection in patients with chronic nonspecific pharyngitis: preliminary study

2007 ◽  
Vol 122 (1) ◽  
pp. 61-64 ◽  
Author(s):  
İ Aladag ◽  
Y Bulut ◽  
M Guven ◽  
A Eyibilen ◽  
K Yelken
Keyword(s):  
Helicobacter Pylori ◽  
Treatment Strategies ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Control Groups ◽  
Chi Square ◽  
Control Subjects ◽  
The Difference ◽  
H Pylori ◽  
And Control

AbstractBackground and objectives:Chronic nonspecific pharyngitis is a chronic inflammation of the pharynx. It is found worldwide, and treatment is difficult. The underlying aetiopathogenesis is still controversial. The aim of this study was to investigate Helicobacter pylori seroprevalence in chronic nonspecific pharyngitis patients without other possible causative factors for chronic pharyngeal irritation and without H pylori gastric mucosal infection.Materials and methods:Forty-one patients with symptoms of chronic nonspecific pharyngitis and 30 healthy control subjects were enrolled in this prospective, controlled, clinical study. In both study and control groups, selected patients were shown to have gastric mucosa uninfected by H pylori, as demonstrated by the 14C-urea breath test. Comprehensive otorhinolaryngological examination did not elicit any factor contributing to the chronic pharyngeal complaint. Serum H pylori immunoglobulin G antibody titres were assayed using serum enzyme-linked immunosorbent assay. The difference between the study and control groups was analysed by the chi-square test (the likelihood ratio was used).Results:Thirty-two of the 41 patients (78 per cent) and 14 of the 30 control subjects (46.7 per cent) were found to be H pylori positive. Patients with chronic nonspecific pharyngitis were found to have a significantly higher rate of H pylori seropositivity than the control group (p = 0.016).Conclusion:These data may be important in developing future treatment strategies for chronic nonspecific pharyngitis.

The effect of lavandula angustifolia in the treatment of depression

2011 ◽  
Vol 26 (S2) ◽  
pp. 624-624 ◽  
Author(s):  
N. Parvin ◽  
S. Farzaneh ◽  
M. Nikfarjam ◽  
N. Shahinfard ◽  
N. Asarzadegan
Keyword(s):  
Depression Score ◽  
Control Group ◽  
Case Group ◽  
Double Blind Study ◽  
Control Groups ◽  
Chi Square ◽  
Double Blind ◽  
Treatment Of Depression ◽  
Severity Of Depression ◽  
And Control

Background and aimMedical plants have been used for centuries as a medicinal agent in treatment of depression and anxiety. The purpose of this study was to explore the effects of the lavendula officinalis on depression in patients using citalopram.MethodsThis clinical trial study was performed in Hajar hospital, Shahrekord, Iran. In this study eighty patients randomly allocated into two groups (40 patients in each group). Patients who complained from depression were studied during a two-month double-blind study. In control group, patients were given 20 mg citalopram twice daily plus placebo and case group were treated with 5 g arial part of dried Lavendula officinalis and citaloperam (20 mg, twice per day). After 4 and 8 weeks, patients were followed for evaluations of their depression and complications. Depression severity was scored using standard Hamilton’s depression questionnaire. Data were analyzed using Chi square and Paired-t test.ResultsAfter 1 month treatment, mean depression score in case and control groups were 15.2 ± 3.6 and 17.5 ± 3.5, respectively (P < 0.05). After 2 months the mean score of depression in case and control groups was 14.8 ± 4 and 16.8 ± 4.6, respectively (P < 0.01). The most common side effects in two groups were confusion and dry mouth, which were not significantly different between two groups.ConclusionLavendula officinalis has a positive effect on depressed patients and may be useful to decrease the severity of depression in patients using other antidepressants.

scholarly journals Altered ex vivo cytokine production in zinc-deficient, pair-fed and marginally zinc-deficient growing rats is independent of serum corticosterone concentrations

2008 ◽  
Vol 100 (4) ◽  
pp. 820-828 ◽  
Author(s):  
Heather J. Hosea Blewett ◽  
Edward S. Rector ◽  
Carla G. Taylor
Keyword(s):  
T Cells ◽  
Cytokine Production ◽  
Ex Vivo ◽  
Control Group ◽  
Zn Deficiency ◽  
Control Groups ◽  
Serum Corticosterone ◽  
Ad Libitum ◽  
And Control ◽  
Deficient Group

The objective of the present study was to examine the effects of dietary Zn deficiency on the ex vivo cytokine production (IL-2, interferon-γ (IFN-γ), IL-6 and IL-10) of isolated thymocytes and splenocytes after mitogenic stimulation with concavalin A and to explore the role of corticosterone in this regulation. Weanling rats were assigned to one of four dietary treatments for 3 weeks: Zn-deficient ( < 1 mg Zn/kg diet, ad libitum), pair-fed (30 mg Zn/kg diet, limited to amount of feed as consumed by the Zn-deficient group), marginally Zn-deficient (10 mg Zn/kg diet, ad libitum) and control (30 mg Zn/kg diet, ad libitum). Thymocytes and splenocytes were isolated for cytokine stimulation and determination of T-cell phenotypes. Serum corticosterone concentrations were determined by ELISA. The Zn-deficient and pair-fed groups had 14-fold higher serum corticosterone concentrations compared with the marginally Zn-deficient and control groups (P < 0·0001). The proportions of thymocyte subsets were not altered in the Zn-deficient, pair-fed or marginally Zn-deficient groups; however, thymocyte IL-2 and IL-6 production in these groups was 33–54 % lower compared with the control group (P < 0·05). The Zn-deficient group had an 18–28 % lower proportion of new T-cells (TCRαβ+CD90+), but no difference in the proportion of new T-cells that were cytotoxic or helper. The Zn-deficient group had a 49–62 % lower production of Th1 cytokines (IL-2), but no difference in the production of Th2 cytokines (IL-6, IL-10) by stimulated splenocytes compared with the pair-fed, marginally Zn-deficient and control groups (P < 0·01). These results indicate that Zn status is associated with altered cytokine production, while in vivo corticosterone concentrations are not associated with ex vivo cytokine production.

388 SUPEROVULATION TREATMENT BY A SINGLE INJECTION OF FSH WITH ALUMINUM HYDROXIDE GEL IN HOLSTEIN CATTLE

2007 ◽  
Vol 19 (1) ◽  
pp. 309
Author(s):  
S. Matoba ◽  
M. Tagawa ◽  
H. Matsuda ◽  
H. Yoshioka ◽  
K. Kimura ◽  
...  
Keyword(s):  
Aluminum Hydroxide ◽  
Single Injection ◽  
Follicular Development ◽  
Advanced Technology ◽  
Inguinal Region ◽  
Control Group ◽  
Corpora Lutea ◽  
Holstein Cattle ◽  
Embryo Recovery ◽  
And Control

The objective of this study was to examine the effect of administration of FSH in aluminum hydroxide gel (Gel; an adjuvant and adsorbent of large molecules) by a single injection on superovulatory response and embryo recovery in cattle. In this study, cloprostenol-synchronized (PGF; Clopromate C; Sumitomo Pharmaceuticals Co., Tokyo, Japan) nonlactating Holstein cows were divided into 2 groups (Gel-treated and Controls) between Days 8 and 11 after estrus in 2 experiments in a crossover design. In Experiment 1, 40 mg FSH (Antrin-R10; Kawasaki Mitaka Pharmaceutical Co., Tokyo, Japan) was mixed with 10 mL aluminum hydroxide suspended in saline at a concentration of 3 mg Al mL-1 and administered by a single IM injection (n = 12; 10 mL-Gel group). Blood samples were collected at 0, 1, 2, 4, 8, and 12 h, and thereafter every 24 h until embryo recovery for measurement of FSH levels in a time-resolved fluoroimmunoassay. In Experiment 2, 40 mg FSH was mixed with 5 mL Gel and injected into fat in the inguinal region (n = 8, 5 mL-Gel group). The Control group in both experiments (n = 2 and n = 8, respectively) received 40 mg FSH twice daily for 4 days in decreasing doses (8, 8, 6, 6, 4, 4, 2, and 2 mg) by IM injection (Experiment 1), or in the inguinal region (Experiment 2). PGF (0.75 mg) was administered twice on the third day of treatment, and cows were inseminated 48 and 60 h after second PGF dose; embryo recovery was performed 7 days later. Follicular development was monitored ultrasonically every 24 h from the first FSH treatment to ovulation, and the numbers of medium (MF, 5–8 mm) and large (LF, &gt;8 mm) follicles, and corpora lutea (CL) were counted on the day of embryo recovery. Data were analyzed by Student&apos;s t-test. In Experiment 1, there were no differences in the mean (� SD) number of CL or transferable embryos between the 10 mL-Gel (10.5 � 9.6 and 6.0 � 8.0, respectively) and Control (14.8 � 9.6 and 9.0 � 6.6, respectively) groups (P &gt; 0.1). The growth of LF and MF in the 10 mL-Gel group occurred 24 h earlier than in the Control group (24 and 48 h after initiation of FSH treatment, respectively; P &lt; 0.05). However, follicle growth stopped at 72 h in the 10 mL-Gel group and at 96 h in the Control group (P &lt; 0.01). FSH concentrations in the 10 mL-Gel group increased markedly to 2.0 � 0.7 ng mL-1 at 12 h, remained there at 24 h, and decreased to 1.0 � 0.3 ng mL-1 at 72 h, whereas FSH concentrations in the Control group increased gradually to 1.1 � 0.3 ng mL-1 at 24 h, remained at 1.2 � 0.3 ng mL-1 from 24 to 96 h, and then decreased to baseline (0.9 � 0.3 ng mL-1) at 120 h (P &lt; 0.05). In Experiment 2, no significant differences in number of CL or transferable embryos were found between the 5 mL-Gel (11.8 � 13.0 and 4.1 � 4.0, respectively) and Control (12.0 � 11.0 and 4.0 � 3.1, respectively) groups, and follicular growth profiles did not differ between groups (P &gt; 0.4). Results suggest that administration of FSH in 5 mL Gel by a single injection in the inguinal region is effective in inducing superstimulation in Holstein cattle. This work was supported by a grant of the Research Project for Utilizing Advanced Technology (04-1676).

Increased Frequency of Left-Handedness in Patients with Unilateral Coronal Synostosis

2009 ◽  
Vol 46 (3) ◽  
pp. 237-244 ◽  
Author(s):  
Albert K. Oh ◽  
John B. Mulliken ◽  
Richard A. LaBrie ◽  
Gary F. Rogers
Keyword(s):  
Cleft Lip ◽  
Control Group ◽  
Study Group ◽  
Healthy Controls ◽  
Control Groups ◽  
Chi Square ◽  
Left Handedness ◽  
Coronal Synostosis ◽  
Chi Square Analysis ◽  
And Control

Objective: Left-handedness reportedly has been more common in persons with neurological afflictions (e.g., stroke) and malformations (e.g., cleft lip with or without cleft palate) that demonstrate marked unilateral involvement. Coronal synostosis is also more frequently unilateral, affecting the right side more commonly than the left. We sought to compare left-handedness in patients with unilateral coronal synostosis versus healthy controls. Subjects: All patients aged 3 years or older with nonsyndromic unilateral coronal synostosis and healthy controls recruited by pediatricians blinded to the study. Main Outcome Measures: Prospective data obtained for all participants included age, gender, and handedness. In patients with unilateral coronal synostosis, the side of synostosis and age at surgery were documented. Left-handedness in the study and control groups was compared using chi-square analysis. Left-handedness also was analyzed in the study group according to side of fusion. Results: Eighty-six patients with nonsyndromic unilateral coronal synostosis comprised the study group; there were 96 controls. The mean ages of the study (8.8 years) and control groups (9.8 years) were not statistically different (p > .05). There were more girls in the study group (67%) than in the control group (56%), but this difference was not statistically significant (p > .05). Left-handedness was documented in 30.2% of the study group and 11.4% of the control group (p < .005). Left-handedness was twice as common in patients with left versus right unilateral coronal synostosis (44.4% versus 20.4%; p < .05). Conclusions: Left-handedness is nearly three times more common in patients with unilateral coronal synostosis than in controls and four times more likely in patients with left-sided fusion.

scholarly journals Effect of Foot Reflexology on Postoperative Pain in Patients Undergoing Tibia Plating Surgery: A Randomized Clinical Trial

2020 ◽  
Vol 10 (3) ◽  
pp. 258-269
Author(s):  
Fatemeh Imani ◽  
◽  
Ebrahim Nasiri ◽  
Houshang Akbari ◽  
Mohammad Reza Safdari ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Postoperative Pain ◽  
Randomized Clinical Trial ◽  
Repeated Measures ◽  
Intervention Group ◽  
Control Group ◽  
Control Groups ◽  
Chi Square ◽  
Chi Square Test ◽  
And Control

Objective: One of the major problems of patients after orthopedic surgeries is acute pain. The present study aims to evaluate the effect of foot reflexology massage on postoperative pain in patients undergoing plating surgery for tibia fracture. Methods: This study is a randomized clinical trial conducted on 96 patients who were candidates for tibia plating surgery referred to Imam Ali Hospital in Bojnourd, Iran, randomly divided into intervention and control groups. Foot reflexology massage in the intervention group was performed on patients’ healthy feet for 10 minutes, one hour before surgery. In the control group, the foot sole was touched for one minute without any pressure. Pain intensity was measured using the standard Visual Analog Scale before and immediately after the intervention and 2, 4, 6, 12 and 24 hours after surgery. Data were analyzed using chi-square test, t-test, repeated measures ANOVA, Mann-Whitney U and Friedman tests. Results: The baseline pain scores in the intervention and control groups were reported 8.1±0.9 and 8.4±0.9, respectively. After the intervention, the pain score in these groups was reduced to 6.9±1.1 and 8.1±1.0, respectively (P<0.001). At other times, up to 24 hours after surgery, the pain reduction was higher in the intervention group (P<0.05). Conclusion: Foot reflexology massage reduces postoperative pain of patients undergoing tibia plating surgery. Therefore, this method can be used to reduce pain and anxiety in orthopedic surgery patients.

148 MICE BLASTOCYST RECONSTRUCTION BY AGGREGATION OF INNER CELL MASS WITH TROPHECTODERM

2013 ◽  
Vol 25 (1) ◽  
pp. 222
Author(s):  
I. P. Emanuelli ◽  
C. P. Godoi ◽  
M. P. M. Mancini ◽  
C. M. Barros ◽  
M. F. G. Nogueira
Keyword(s):  
Present Model ◽  
Inner Cell Mass ◽  
Cell Mass ◽  
Cell Aggregation ◽  
Control Group ◽  
Control Groups ◽  
Chi Square ◽  
Trophectoderm Cells ◽  
And Control

In order to reduce fetal losses of bovine clones the replacement of trophectoderm (TE) by microinjection of immunosurgically isolated inner cell mass (ICM) was proposed. It was reported that those techniques could damage both ICM and TE. An alternative to decrease this problem would be the technique of cell aggregation by approximation. Currently it has been used only in pre-compaction embryos. The aims of this study were to evaluate the effectiveness to aggregate post-compaction embryos and to verify the feasibility of reconstructed blastocysts production by ICM and TE approximation. Mice (Swiss Webster, SW; and C57BL/6/EGFP, EGFP) were superovulated to obtain embryos 2.5 to 3.5 days post-coitus. In both control groups (CG; exp. 1 and 2), whole embryos from 8 cells to early morula stages and without zona pellucida were aggregated. In all experiments, bisection was performed with a blade controlled by micromanipulator to produce two fragments according to the requirements of each experiment (i.e. demi embryos in Exp. 1 and Exp. 2 or TE fragment and whole ICM in Exp. 3). The joined fragments were in vitro cultured in microwell (300 µm diameter and based on well of the well system) filled with 400 µL of KSOMaa, covered with mineral oil by 24 h (incubation 37°C, 5% of CO2 and saturated humidity). Embryonic aggregation rate (AR) was evaluated by detection of a single and cohesive cell mass (CG from Exp. 1 and Exp. 2) or by the presence of a typical morphologically blastocyst (all the remaining groups). Only to validate AR evaluation, 25% of the aggregation attempts were performed with distinct phenotype embryos (EGFP and SW) and they could be tracked under epifluorescence. In Exp. 1, the aggregation by approximation was tested to evaluate embryonic stages: 2 demi-blastocysts (2DB; n = 28), demi-morula and demi-blastocyst (DMDB; n = 20) and control group (CG; n = 25). In Exp. 2, an adhesive agent (phytohemagglutinin; PHA) and fragment increasing were used in the groups: 2DB (n = 24), 4 demi-blastocysts (4DB, that is four half-blastocyst) and CG (n = 22). After aggregation validation (Exp. 1 and Exp. 2), blastocyst reconstruction by the approximation of ICM and TE fragments (with PHA presence) was tested on groups: 1 TE fragment and 1 ICM (TI; n = 48) and 2 TE fragments and 1 ICM (2T1I; n = 17). The rates were analyzed by chi-square and Fisher’s exact tests (significance of 5%). In experiments 1 (3.6; 15.0; and 60.0%, respectively to 2DB, DMDB, and CG) and 2 (8.3; 36.4; and 77.3%, respectively to 2DB, 4DB, and CG), the AR differed among groups with exception of 2DB and DMDB (exp. 1; P > 0.05). In Exp. 3, there was no difference on the AR between TI and 2T1I (27.1 and 29.4%, respectively). Despite the low adhesion potential of the trophectoderm cells, is feasible to produce chimeric embryos by aggregation. We infer that the use of an adhesive agent could increase AR maintaining the contact of the embryonic fragments. The proposed technique was practical and effective for blastocyst reconstruction. Additionally, the present model established in mice is about to be tested in cattle for further validation. Financial support: FAPESP.

192 The use of human chorionic gonadotropin seven days after synchronized estrus for the increase of luteal tissue in Morada Nova ewes

2019 ◽  
Vol 31 (1) ◽  
pp. 220
Author(s):  
G. B. Vergani ◽  
J. T. Trevizan ◽  
V. S. A. Pereira ◽  
J. F. Fonseca ◽  
A. R. Garcia ◽  
...  
Keyword(s):  
Body Condition Score ◽  
Physiological Solution ◽  
Saline Control ◽  
Favourable Effect ◽  
Control Group ◽  
Corpora Lutea ◽  
Control Groups ◽  
Luteal Tissue ◽  
Condition Score ◽  
And Control

The study was performed to evaluate whether the use of hCG 7 days after synchronized oestrus in Morada Nova ewes would increase the number and size of corpora lutea. Multiparous Morada Nova ewes (n=115, mean weight of 36.6kg, body condition score 3.13 on 1 to 5 scale) were used. Oestrus was synchronized by using an intravaginal sponge impregnated with medroxyprogesterone acetate (60mg, Progespon®, Zoetis, Parsippany, NJ, USA) for 6 days and eCG (200IU, IM Novormon®, Zoetis) plus PGF2α analogue (37.5μg, D-cloprostenol, IM, Vetglan®, Hertape Calier, Spain), both administered 24h before the sponge removal. Seven days after the synchronized oestrus, hCG (300IU, IM, Vetecor®, Hertape Calier; n=57) or normal saline (control group, 1mL, IM, 0.9% NaCl, Eurofarma Laboratory SA, Sao Paulo, Brazil; n=58) was injected. B-mode ultrasound examinations of the ovaries were performed using the equipment MyLab Vet 30 Gold (Esoate, Genoa, Italy) on Day 7 (corresponding to the day of hCG or physiological solution administrations), and 6 days later (Day 13). The number of corpora lutea present and the size of luteal tissue (sum of diameter and area) were determined. Data were analysed by ANOVA with Tukey’s post hoc test (mean±s.e.m.) using SAS software (SAS Institute Inc., Cary, NC, USA). On Day 7, the number of corpora lutea was similar (P&gt;0.05) between the hCG and control groups (1.58±0.09v. 1.57±0.08, respectively); however, the number was higher on Day 13 (P&lt;0.05) in the hCG group (2.65±0.13) than in the control group (1.69±0.07). Similarly, there was no difference (P&gt;0.05) between groups in diameter (16.9±0.82v. 16.0±0.71mm) and area (1.61±0.07v. 1.45±0.06cm2) for hCG and control groups, respectively, on Day 7. Differences were observed on Day 13, such that the hCG ewes had luteal tissue of larger (P&lt;0.0001) diameters (27.13±1.25v. 18.44±0.85mm) and area (2.81±0.13v. 1.71±0.08cm2) than ewes of the control group. In conclusion, 300IU of hCG injected 7 days after synchronized oestrus is effective to increase the number of corpora lutea and in the size of luteal tissue. Despite indications of a favourable effect on luteal dynamics, the effects on progesterone production and conception rate need to be examined. This study was supported by CNPq and EMBRAPA (process no. 02.13.06.026.00.02).

Effect of a mobile-based educational app on blood pressure of patients with hypertension

2020 ◽  
pp. e001577
Author(s):  
Fereshteh Falah ◽  
S A Sajadi ◽  
A H Pishgooie
Keyword(s):  
Blood Pressure ◽  
Military Personnel ◽  
Intervention Group ◽  
Control Group ◽  
Control Groups ◽  
Chi Square ◽  
Significance Level ◽  
Significant Difference ◽  
And Control ◽  
Paired T Test

BackgroundHypertension is known as one of the most important non-communicable pervasive diseases.ObjectiveThe purpose of the present study was to determine the effect of a mobile-based educational app on the blood pressure (BP) of patients with hypertension.MethodsThis clinical trial was conducted on 66 military personnel who were definitively diagnosed with hypertension by a physician, and then assigned randomly into two groups as intervention (receiving mobile-based educational app) and control (receiving standard medical management but no app). Before the intervention, BP levels of both groups were measured with a calibrated sphygmomanometer. After 6 weeks, the BPs of both groups were remeasured using the same sphygmomanometer. Thereafter, descriptive and inferential statistics, including paired t-test, Mann-Whitney, Chi-square and Wilcoxon tests, were used. The data obtained were analysed using SPSS-21 software at a significance level of p<0.05.ResultsComparison of the intervention and control groups showed no statistically significant difference between the groups in systolic BP (p=0.479) and diastolic BP (p=0.851) in the pre-intervention phase, but after the intervention, systolic and diastolic BP levels were significantly lower in the intervention group than in the control group (p=0.0001).ConclusionThe results suggested that the mobile-based educational app had a significant effect on reducing BP in patients with hypertension. Therefore, using this app is recommended for those military personnel with hypertension.

scholarly journals The Effect of Aromatherapy by Inhalation and Massage on Radiotherapy-induced Fatigue in Patients With Cancer

2020 ◽  
Vol 6 (2) ◽  
pp. 79-86
Author(s):  
Mojgan Moradi ◽  
◽  
Alice Khachian ◽  
Farshad Amini Behbahani ◽  
Kiarash Saatchi ◽  
...  
Keyword(s):  
Routine Care ◽  
Control Group ◽  
Control Groups ◽  
Chi Square ◽  
Significance Level ◽  
Fatigue Score ◽  
Patients With Cancer ◽  
Spss Software ◽  
Post Hoc ◽  
And Control

Background: Fatigue is one of the most prevalent and debilitating complications of cancer and its treatments. Patients undergoing radiotherapy experience some degrees of fatigue. Complementary medicine methods have reduced the complications of treatments in many disorders. Accordingly, the present study was conducted to compare the effect of aromatherapy by inhalation and massage on radiotherapy-induced fatigue in patients with cancer. Methods: In this randomized clinical trial, 105 patients with cancer undergoing radiotherapy in the oncology ward of Firouzgar Hospital in Tehran, Iran were selected conveniently based on the inclusion criteria and were randomly assigned into three groups of inhalation aromatherapy, massage aromatherapy, and control groups. In the first group, viola and almond oil were inhaled, in the second group, the Swedish massage was performed using aromatic oil, and the control group received routine care. Fatigue was measured by the Multidimensional Fatigue Inventory (MFI) before, and at the end of the intervention. The data were analyzed by descriptive and inferential statistics (ANOVA, Paired T-tests, Fischer’s exact, and Chi-square tests) using SPSS software V. 16. The significance level was considered as P≤0.05. Results: The findings showed that the three studied groups had no significant statistical difference in terms of demographic characteristics before the intervention. Fatigue score was significantly different in all three groups after both interventions (P<0/001), which indicated a decrease in fatigue in the two test groups. However, according to Scheffe post hoc test, massage aromatherapy was more effective in reducing fatigue resulting from radiotherapy. Conclusion: The results of this study showed that massage aromatherapy was more effective in reducing radiotherapy-induced fatigue in patients with cancer. It is recommended that future studies recruit another group that receives the only massage.

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