Effect of high concentrations of dietary vitamin e during various age periods on performance, plasma vitamin e and meat stability of broiler chicks at 7 weeks of age

1992 ◽  
Vol 33 (2) ◽  
pp. 393-402 ◽  
Author(s):  
I. Bartov ◽  
M. Frigg
2014 ◽  
Vol 112 (9) ◽  
pp. 1575-1585 ◽  
Author(s):  
Yang Zhao ◽  
Frank J. Monahan ◽  
Breige A. McNulty ◽  
Mike J. Gibney ◽  
Eileen R. Gibney

Vitamin E is believed to play a preventive role in diseases associated with oxidative stress. The aims of the present study were to quantify vitamin E intake levels and plasma concentrations and to assess dietary vitamin E adequacy in Irish adults. Intake data from the National Adult Nutrition Survey were used; plasma samples were obtained from a representative cohort of survey participants. Plasma α- and γ-tocopherol concentrations were measured by HPLC. The main sources of vitamin E in the diet were ‘butter, spreadable fats and oils’ and ‘vegetables and vegetable dishes’. When vitamin E intake from supplements was taken into account, supplements were found to be the main contributor, making a contribution of 29·2 % to vitamin E intake in the total population. Supplement consumers had significantly higher plasma α-tocopherol concentrations and lower plasma γ-tocopherol concentrations when compared with non-consumers. Consumers of ‘vitamin E’ supplements had significantly higher vitamin E intake levels and plasma α-tocopherol concentrations compared with consumers of other types of supplements, such as multivitamin and fish oil. Comparison with the Institute of Medicine Estimated Average Requirement of 12 mg/d indicated that when vitamin E intake from food and supplement sources was taken into account, 100 % of the study participants achieved the recommended intake levels. When vitamin E intake from food sources was taken into account, only 68·4 % of the females were found to achieve the recommended intake levels compared with 99·2 % of the males. The results of the present study show that dietary vitamin E intake has a significant effect on plasma α- and γ-tocopherol concentrations. Furthermore, they show that the consumption of supplements is a major contributor to overall intake and has a significant effect on plasma vitamin E concentrations in the Irish population.


1980 ◽  
Vol 33 (11) ◽  
pp. 2394-2395 ◽  
Author(s):  
Robert E. Keith ◽  
Barbara M. Chrisley ◽  
Judy A. Driskell

1968 ◽  
Vol 46 (2) ◽  
pp. 345-355 ◽  
Author(s):  
R. C. Siddons ◽  
C. F. Mills

1. Glutathione peroxidase activity (EC1.11.1.9) and erythrocyte stability were measured in Friesian bull calves which were given for 36 weeks semi-purified diets either adequate or low in selenium or vitamin E or both.2. Dietary Se or vitamin E content had no effect on growth rate and haematological vaiues. None of the calves exhibited clinical deficiency symptoms and serum aspartate amino transferase (EC 2.6.1.1) and creatine phosphokinase (EC 2.7.3.2) activities remained normal. Heart and skeletal muscles of all calves appeared macroscopically and microscopically normal at autopsy.3. Glutathione peroxidase activity in plasma, blood and other tissues, except the testis, was significantly lower in calves receiving low dietary Se but was independent of dietary vitamin E content.4. Plasma vitamin E levels decreased rapidly and to very low levels in calves given low vitamin E diets irrespective of the Se content of the diet.5. A low dietary vitamin E intake increased the susceptibility of erythrocytes to auto- and peroxidative haemolysis whereas a low Se intake in the presence of adequate vitamin E did not. However, erythrocytes from calves receiving low Se and low vitamin E were more susceptible to peroxidative haemolysis than erythrocytes from calves receiving low vitamin E and adequate Se. The effect of dietary vitamin E content on osmotic haemolysis induced by hypotonic saline was variable.6. The results suggest that measurement of blood glutathione peroxidase activity and the susceptibility of erythrocytes to auto- or peroxidative haemolysis could be used for the differential diagnosis of subclinical Se and vitamin E deficiency in ruminants.


2013 ◽  
Vol 53 (3) ◽  
pp. 247 ◽  
Author(s):  
C. R. Fancote ◽  
P. E. Vercoe ◽  
K. L. Pearce ◽  
I. H. Williams ◽  
H. C. Norman

Vitamin E deficiency is common in sheep during summer and autumn in Mediterranean environments because of the lack of green feed. Deficiency of Vitamin E can lead to the development of nutritional myopathy, a condition causing heart and skeletal muscle damage which, in severe cases, can lead to death of the animal. Saltbush (Atriplex spp.) contains high concentrations of Vitamin E, so providing sheep with access to saltbush during summer may improve their Vitamin E status and prevent Vitamin E deficiency. We wished to determine whether backgrounding lambs on saltbush over summer and autumn (i.e. graze saltbush-based pastures for several weeks before finishing them to condition suitable for slaughter) would prevent Vitamin E deficiency and nutritional myopathy and compared the effectiveness of this strategy in preventing Vitamin E deficiency to a commercially available synthetic Vitamin E supplement. Ten-month-old cross-bred lambs (n = 48) were backgrounded on dry, senesced (control) or saltbush-based pastures for 8 weeks during summer. After backgrounding they were fed a grain-based finishing ration containing low levels of Vitamin E for a further 5 weeks. We found that while grazing saltbush the plasma Vitamin E concentrations of lambs increased from 1.1 to 2.6 mg/L within 3 weeks, concentrations that were significantly higher than the concentrations in the lambs that did not have access to saltbush during backgrounding (P < 0.001). The improved Vitamin E concentrations corresponded with a reduction in the incidence of nutritional myopathy, with none of the lambs grazing saltbush showing any biochemical signs of myopathy, whereas 17% of lambs backgrounded on control pastures had elevated plasma concentrations of creatine kinase that were indicative of subclinical nutritional myopathy. During the subsequent finishing phase, lambs that had not had access to saltbush during backgrounding were all Vitamin E deficient and, of these, 8.5% were diagnosed with subclinical nutritional myopathy. By contrast, none of the lambs backgrounded on saltbush was Vitamin E deficient nor did they have any biochemical evidence of Vitamin E-responsive myopathy. The present study demonstrated that saltbush is a valuable source of Vitamin E for livestock that can reduce the incidence of subclinical nutritional myopathy in lambs during summer and prevent plasma Vitamin E concentrations becoming deficient for up to 5 weeks after saltbush is removed from the diet.


2004 ◽  
Vol 91 (4) ◽  
pp. 539-550 ◽  
Author(s):  
S. Chikunya ◽  
G. Demirel ◽  
M. Enser ◽  
J. D. Wood ◽  
R. G. Wilkinson ◽  
...  

The present study investigated the susceptibility of dietaryn-3 PUFA to ruminal biohydrogenation, the stability of ingested vitamin E in the rumen and the subsequent uptake of PUFA and vitamin E into plasma. Six cannulated sheep were assigned to six diets over five 33d periods, in an incomplete 6×5 Latin square. The diets, based on dried grass, were formulated to supply 50g fatty acids/kg DM using three lipid sources: Megalac®(calcium soap of palm fatty acid distillate; Volac Ltd, Royston, Herts., UK), linseed (formaldehyde-treated; Trouw Nutrition, Northwich, Ches., UK) and linseed–fish oil (formaldehyde-treated linseed+fish oil). The diets were supplemented with 100 or 500mg α-tocopheryl acetate/kg DM. Fat source or level of vitamin E in the diet did not alter microbial activity in the rumen. Biohydrogenation of linoleic acid (18:3n-6; 85–90%), linolenic acid (18:3n-3; 88–93%), docosahexaenoic acid (22:6n-3; 91%) and EPA (20:5n-3; 92%) was extensive. Feeding formaldehyde-treated linseed elevated concentrations of 18:3n-3 in plasma, whilst 22:6n-3 and 20:5n-3 were only increased by feeding the linseed–fish oil blend. Duodenal recovery of ingested vitamin E was high (range 0·79–0·92mg/mg fed). High dietary vitamin E was associated with increased plasma α-tocopherol (2·57v.1·46μg/ml for 500 and 100mg α-tocopheryl acetate/kg DM respectively), although all concentrations were low. Plasma vitamin E levels, however, tended to decrease as the type and quantity of PUFA in the diet increased. The present study illustrates that nutritionally beneficial PUFA in both fish and linseed oils are highly susceptible to biohydrogenation in the rumen. Although α-tocopheryl acetate resisted degradation in the rumen, plasma vitamin E status remained deficient to borderline, suggesting either that uptake may have been impaired or metabolism post-absorption increased.


1991 ◽  
Vol 71 (4) ◽  
pp. 1181-1186 ◽  
Author(s):  
J. W. G. Nicholson ◽  
Anne-Marie St-Laurent

Twelve Holstein cows in each of two replicates were used to determine the effect of forage type and vitamin E supplementation on the oxidative stability of milk. Alfalfa or corn silage was fed ad libitum as the sole roughage, with a concentrate to milk ratio of 1:2.5. Half the cows on each forage were fed 7000 IU d−1 of dL-α-tocopherol acetate top-dressed on the concentrate in two feedings per day over a 4-wk period. Cows consuming the alfalfa silage had higher (P < 0.05) plasma vitamin E content, but there were no differences in milk vitamin E or flavor due to forage type. Supplementing the diets with vitamin E resulted in higher (P < 0.01) vitamin E content of plasma and milk and improved milk oxidative stability. There was an interaction (P = 0.03) between forage type and vitamin E supplementation for oxidative flavor score in week 2. Supplementing the corn silage diet with 7000 IU d−1 of vitamin E resulted in almost complete elimination of oxidized flavor in milk within 1 wk of starting supplementation. However, supplementing the alfalfa silage diet had no effect on flavor over the first 3 wk of feeding. It is apparent that the vitamin E content of milk is not the sole determinant of its oxidative stability. Key words: Spontaneous oxidation, flavor, milk, vitamin E, alfalfa, corn silage, cow


2006 ◽  
Vol 40 (4) ◽  
pp. 689-697 ◽  
Author(s):  
Richard S. Bruno ◽  
Scott W. Leonard ◽  
Jeffery Atkinson ◽  
Thomas J. Montine ◽  
Rajasekhar Ramakrishnan ◽  
...  

2021 ◽  
pp. 104672
Author(s):  
Saman Lashkari ◽  
Søren K. Jensen ◽  
Christina B. Hansen ◽  
Kenneth Krogh ◽  
Per Theilgaard ◽  
...  

2015 ◽  
Vol 40 (2) ◽  
pp. 79-84 ◽  
Author(s):  
T Bashar ◽  
N Akhter

In acute myocardial infarction (AMI), lack of oxygen delivery to myocardium leads to generation of reactive oxygen species (ROS) which play an important role in the pathogenesis of AMI. Endogenous anti-oxidants protect the myocardial tissues from the deleterious effect of free radical mediate injury. The study evaluates the extent of oxidative stress and antioxidant status against ROS in AMI patients and amelioration of oxidative stress after regular treatment and also assesses the association between oxidative stress and risk factors for atherosclerosis like dyslipidemia and diabetes mellitus (DM).The study was conducted on 72 AMI patients and age and sex matched 18 healthy controls. Patients were assigned to four groups, AMI without dyslipidemia or DM, with dyslipidemia, with DM and with both dyslipidemia and DM. Plasma malondialdehyde (MDA) and GSH content and vitamin E levels were determined on admission into hospital and on the 5th day of treatment. Plasma MDA level increased significantly (p<0.001) and erythrocyte GSH and plasma vitamin E levels were decreased (p<0.001) in all the groups of patients as compared to control. On the 5th day of regular treatment MDA level reduced (p<0.001) and GSH and vitamin E levels increased (p<0.001) in patients. The plasma MDA level was significantly higher (p<0.001) in patients with both dyslipidemia and DM or with only DM in comparison to patients without dyslipidemia and DM. The difference in the GSH level between patients with risk factors and without risk factors was not significant. It may be conclude that an imbalance exists between oxidant and antioxidant molecules in AMI patients which shift towards oxidative side and regular treatment restores this balance. There may be some association between oxidative stress in AMI and risk factors like dyslipidemia and diabetes mellitus.Bangladesh Med Res Counc Bull 2014; 40 (2): 79-84


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