Navel orange peel hydroethanolic extract as a phytogenic feed supplement: impacts on growth, feed intake, nutrient digestibility, and serum metabolites of heat stressed growing rabbits

2021 ◽  
pp. 1-12
Author(s):  
Adham A. Al-Sagheer ◽  
Usama M. Abdel Monem ◽  
Eslam E. Sayed-Ahmed ◽  
Bakry A. Khalil
Keyword(s):  
Feed Intake ◽  
Orange Peel ◽  
Nutrient Digestibility ◽  
Navel Orange ◽  
Feed Supplement ◽  
Serum Metabolites ◽  
Hydroethanolic Extract

Navel orange peel hydroethanolic extract, naringin and naringenin have anti-diabetic potentials in type 2 diabetic rats

2017 ◽  
Vol 94 ◽  
pp. 197-205 ◽  
Author(s):  
Osama M. Ahmed ◽  
Mohamed A. Hassan ◽  
Sanaa M. Abdel-Twab ◽  
Manal N. Abdel Azeem
Keyword(s):  
Orange Peel ◽  
Diabetic Rats ◽  
Navel Orange ◽  
Hydroethanolic Extract ◽  
Type 2 Diabetic

scholarly journals The Preventive Effects and the Mechanisms of Action of Navel Orange Peel Hydroethanolic Extract, Naringin, and Naringenin in N-Acetyl-p-aminophenol-Induced Liver Injury in Wistar Rats

2019 ◽  
Vol 2019 ◽  
pp. 1-19 ◽  
Author(s):  
Osama M. Ahmed ◽  
Hanaa I. Fahim ◽  
Heba Y. Ahmed ◽  
Hessah Mohammed Al-Muzafar ◽  
Rasha R. Ahmed ◽  
...  
Keyword(s):  
Liver Injury ◽  
Wistar Rats ◽  
Orange Peel ◽  
Mechanisms Of Action ◽  
Navel Orange ◽  
Oral Gavage ◽  
Male Wistar Rats ◽  
Hydroethanolic Extract ◽  
Preventive Effects ◽  
Peel Extract

N-Acetyl-p-aminophenol (APAP) or acetaminophen is the most common drug ingredient worldwide. It is found in more than 600 different over-the-counter and prescription medicines. Its long-term and overdose use is highly toxic and may result in liver injury. Thus, this study was designed to assess the preventive effects and to suggest the mechanisms of action of the navel orange peel hydroethanolic extract, naringin, and naringenin in APAP-induced hepatotoxicity in male Wistar rats. APAP was administered to male Wistar rats at a dose level of 0.5 g/kg body weight (b.w.) by oral gavage every other day for 4 weeks. APAP-administered rats were treated with the navel orange peel hydroethanolic extract (50 mg/kg b.w.), naringin (20 mg/kg b.w.), and naringenin (20 mg/kg b.w.) by oral gavage every other day during the same period of APAP administration. The treatments of APAP-administered rats with the peel extract, naringin, and naringenin produced a significant decrease in the elevated serum AST, ALT, ALP, LDH, and GGT activities as well as total bilirubin and TNF-αlevels while they induced a significant increase in the lowered serum albumin and IL-4 levels. The treatments also resulted in a significant decrease in the elevated liver lipid peroxidation and enhanced the liver GSH content and SOD, GST, and GPx activities as compared with APAP-administered control; the peel extract was the most potent in improving the liver LPO, GSH content, and GPx activity. In addition, the three treatments significantly downregulated the elevated hepatic proapoptotic mediators p53, Bax, and caspase-3 and significantly upregulated the suppressed antiapoptotic protein, Bcl-2, in APAP-administered rats. In association, the treatments markedly amended the APAP-induced liver histopathological deteriorations that include hepatocyte steatosis, cytoplasmic vacuolization, hydropic degeneration, and necrosis together with mononuclear leucocytic and fibroblastic inflammatory cells’ infiltration. In conclusion, the navel orange peel hydroethanolic extract, naringin, and naringenin may exert their hepatopreventive effects in APAP-administered ratsviaenhancement of the antioxidant defense system and suppression of inflammation and apoptosis.

Growth performance and nutrient digestibility of Wistar albino rats fed processed dehulled jack bean (Canavalia ensiformis)

2020 ◽  
Vol 40 (2) ◽  
pp. 104-111
Author(s):  
O. A. Abu ◽  
O. H. Amusa ◽  
R. O. Atoyebi ◽  
R. A. Kehinde ◽  
F. C. Nworgu
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Feed Intake ◽  
Nutrient Digestibility ◽  
Albino Rats ◽  
Weight Changes ◽  
Feed Conversion ◽  
Body Weight Changes ◽  
Final Body Weight ◽  
Jack Bean

A total of fifty 3-4 weeks old albino rats of the Wistar strain weighing 50-60g were randomly allocated to five dietary treatments in a completely randomized block design to investigate the growth performance and nutrient digestibility of the rats fed diets containing processed dehulled jack bean. Five diets were formulated to contain casein (T1)-control diet, dehulled jack bean soaked in filtrate obtained from raw pap(T2), dehulled jack bean soaked in lye solution (T3), dehulled jack bean boiled for 15minutes (T4) while a protein free diet served as a negative control (T5). The experiment lasted for 28-days.Dehulled jack bean significantly (P>0.05) influenced the growth parameters measured for the Wistar rats. Rats on control diets had the highest value for all the growth indices, feed intake (210.90g), final body weight (103.40g), body weight changes (41.90g), feed conversion ratio (5.10) and protein efficiency ratio (1.41). Rats on T2 (soaked in ‘ogi’ liquor) had feed intake value of (147.40g), followed by rats on T4 (boiled for 15minutes) (117.00g), T5 (negative control) (119.07) and T3 (soaked in lye solution) (79.40g) respectively. Rats on T4 had the highest value for final body weight (67.80g), body weight changes (6.30g), feed conversion ratio (12.27) and protein efficiency ratio (0.25) while rats on T3 had the lowest value for final body weight (67.80g), body weight changes (-32.45g), total feed intake (79.40g) with FCR of (-0.96) for the tested diets. Wistar rats placed on lye treated diet had depressed body weight changes of 59.8% compared to the control. Digestibility studies however showed that rats on control diets had the highest digestibility value of DM and other nutrients, while there was no significant (P<0.05) difference in digestibility value of CF, significant (P>0.05) differences existed in DM, digestibility value of CP, EE and Ash. Rats on T3 and T5 had the lowest digestibility value for Ash (11.48) and CP (37.66). Rats fed dehulled jack bean seed soaked in ogi liquor and boiled for 15minutes showed slight improvement in growth performance and nutrient utilization over those fed lye soaked jack bean. All the processing methods were ineffective when compared to the performance of rat fed casein based diets.

scholarly journals Effect of dietary Black pepper (Piper nigrum) on the performance of broiler

2015 ◽  
Vol 44 (2) ◽  
pp. 120-127 ◽  
Author(s):  
EK Ndelekwute ◽  
KD Afolabi ◽  
HO Uzegbu ◽  
UL Unah ◽  
KU Amaefule
Keyword(s):  
Feed Intake ◽  
Protein Efficiency Ratio ◽  
Live Weight ◽  
Black Pepper ◽  
Nutrient Digestibility ◽  
Energy Utilization ◽  
Piper Nigrum ◽  
Efficiency Ratio ◽  
Gain Ratio ◽  
Dietary Treatments

An experiment was conducted to determine the dietary effect of different levels of ground black pepper (Piper nigrum) on growth performance and apparent nutrient digestibility of broiler chickens. There were five dietary treatments each containing 0, 0.25, 0.50, 0.75 and 1.00 % black pepper (BP) fed at both starter and finisher phases. One hundred and fifty (150) day old chicks of Arbor-acre strain were divided into five dietary groups having three replication with 10 in each. The five dietary treatments were randomly assigned into five groups. The birds were fed and watered ad libitum. At the starter phase 0.25 and 0.5 % BP improved live weight significantly (p<0.05). Feed intake was significantly (p<0.05) reduced at 1.00% BP. There were no significant differences (P>0.05) in daily gain, feed: gain ratio and protein efficiency ratio. At the finisher phase, final live weight was improved by 0.25% (p<0.05). Final live weight, feed intake, weight gain, feed: gain ratio and protein efficiency ratio were negatively affected by 0.75 and 1.0%BP. Fecal moisture was significantly (P<0.05) reduced by 0.25% while dry matter, protein and ether extract digestibility were improved by all the levels of BP. None of the BP levels improved crude fibre digestibility (p>0.05) over the control. NFE and energy utilization were improved by 0.25 and 0.5%, but significantly (p<0.05) reduced by 1.00% BP.Bang. J. Anim. Sci. 2015. 44(2): 120-127

scholarly journals Performance and nutrient digestibility of crossbred weaned pigs fed raw pride of barbados (Caesalpina pulcherrima) seed meal

2020 ◽  
Vol 44 (1) ◽  
pp. 185-191
Author(s):  
A. A. Ogunbode ◽  
A. F. Baderinwa ◽  
I. O. Gbemisola
Keyword(s):  
Feed Intake ◽  
Control Diet ◽  
Nutrient Digestibility ◽  
Conversion Ratio ◽  
Feed Conversion Ratio ◽  
Seed Meal ◽  
Feed Conversion ◽  
Weaned Pigs ◽  
Large White ◽  
Final Body Weight

Deficit of conventional feed resources in meeting increased demand has led to hike in their prices culminating in soaring cost of livestock feed. This has necessitated the search for cheap and easily available alternatives. Pride of barbados seed which constitute a waste has potential of becoming a cheap and easily available feed resource. Performance and nutrient digestibility of dietary inclusion of raw pride of barbados seed meal was evaluated in an eight week feeding trial. Atotal of sixteen crossbred (Large White x Landrace) weaned pigs of eight weeks of age were weighed and allotted to four dietary treatments with four pigs each being a replicate in a completely randomized design. Diet 1 (control) was without raw pride of barbados seed meal while 5%, 10% and 15% of virgin raw pride of barbados were included in diets 2,3 and 4 respectively. Weekly weight gain, daily feed intake, feed conversion ratio and nutrient digestibility of raw pride of barbados seed meal was also determined. Results revealed a significant average final body weight of 16.75kg (diet 3) to 24.50kg (diet 4).The pigs fed 15% raw pride of barbados had the highest feed intake of 137.20kg in diet 4 while the lowest feed intake was obtained in pigs fed 10% (diet 3) inclusion level of raw pride of barbados. Pigs maintained on the control diet had the best feed conversion (7.60kg) while the pigs fed diet 3 had the lowest feed conversion ratio (8.93kg). Crude protein, ether extract and dry matter digestibility was highest at T4 (84.15%, 80.21% and 86.70%) respectively while the least values (68.71%, 65.75% and 71.10% was obtained in T2 and T3 respectively. This study concluded that 15% inclusion of raw pride of barbados in the diets of crossbred weaned pigs had no deleterious effect on performance and nutrient digestibility of pigs.

scholarly journals Feed intake, nutrient utilisation and growth performance of West African dwarf rams fed silage combinations of maize forage and Mucuna pruriens foliage

2021 ◽  
Vol 44 (3) ◽  
pp. 354-365
Author(s):  
B. O. Alabi ◽  
T. O. Ososanya
Keyword(s):  
Growth Performance ◽  
Feed Intake ◽  
Crude Protein ◽  
Nutrient Digestibility ◽  
West African ◽  
Mucuna Pruriens ◽  
Weight Changes ◽  
West African Dwarf ◽  
Standard Procedures ◽  
Nutrient Utilisation

Crude protein is essentially needed for ruminants but expensive to supply. Mucuna puriens is a high yielding domesticated legume. When the legume is strategically combined with a fibre source, it will make a good diet for ruminants. Thus, a study was carried out to assess the effect of ensiling mucuna with maize forage on performance of rams. In the study, rams were fed silage combinations of Maize Forage (MF) and Mucuna pruriens foliage (MPF). Downy mildew and streak resistant (DMR-SR) yellow variety maize was planted and harvested as MF at six weeks of growth and ensiled with MPF at four levels : 1:0, 3:1, 1:1 and 1:3 for 21 days. All the four silages were fed to 20 WAD rams (12.00±0.25 Kg) in a completely randomised design for 105 days. Proximate composition of the silages, apparent nutrient digestibility of silages in WAD rams, feed intake and weight changes were determined using standard procedures, while feed conversion ratio was computed using standard procedures. Data obtained were analysed using descriptive statistics and ANOVA at α0.05...The dry matter (DM) was significantly higher in T1 (25.65±0.62) and T2 (23.48±0.47) than T3 (21.80±0.41) and T4 (21.57±0.40). The crude protein (CP) was highest in T4 (13.0±0.6) and least in T1 (8.0±0.2). The crude fibre was significantly higher in T1 (26.4±2.6) and T2 (26.2±2.0) than T3 (24.0±1.8) and T4 (21.6±0.9). Apparent digestibility of neutral detergent fibre (NDF) was highest in T2 (59.2±1.7) and least in T4 (37.7±1.9), while percentage nitrogen retention was significantly higher in T2 (43.2±3.8) and lower in T1 (20.0±4.3). The FCR for rams fed T2 was significantly lower (8.84±1.2) than T1 (9.76±0.80), T3 (9.60 ±0.60) and T4 (11.50±0.90) Ensiling maize forage with Mucuna pruriens foliage at 3:1 enhanced nutrient digestibility and growth performance in West African dwarf rams without any deleterious effect.

scholarly journals Growth performance, blood parameters and production cost of broiler chickens fed dietary sweet orange peel meal diets with and without enzyme addition

2020 ◽  
Vol 46 (1) ◽  
pp. 37-50
Author(s):  
T. A. Sunmola ◽  
C. D. Tuleun ◽  
O. I. A. Oluremi
Keyword(s):  
Weight Gain ◽  
Growth Performance ◽  
Feed Intake ◽  
Broiler Chickens ◽  
Production Cost ◽  
Sweet Orange ◽  
Control Diet ◽  
Orange Peel ◽  
Blood Parameters ◽  
Final Weight

The growth performance, blood parameters and production cost of two hundred and fifty two (252) Abor acre plus broiler chickens fed sweet orange peel meal (SOPM) with and without enzymes were investigated. The experimental diets consist of control (T ), maize was 0 replaced with SOPM at 15, 20 and 25 % without exogenous enzymes to form T , T and T 1 2 3 respectively, and another supplemented with exogenous enzyme to form T , T and T 4 5 6 respectively. The birds were randomly allocated to seven treatment groups replicated three times to have 12 birds per replicate and were fed experimental diet ad-libitum for eight weeks. Result showed that broiler chickens fed control diet (T ) had significantly (P<0.05) 0 higher final weight (FW) of 2.44kg, weight gain (WG) of 42.91, feed intake (FI) of 86.53, better feed conversion ratio (FCR)of 2.01 and protein conversion ratio (PCR)of 0.44 compared to other dietary treatments. Broiler chickens fed T and T had significantly 1 4 (P<0.05) higher final weight of 1.98 and 1.98 kg, weight gain of 34.69 and 34.71 g and feed intake of 78.35 and 81.63 g respectively while significantly (P<0.05) least values of 1.75 and 1.80 kg final weight, 30.73 and 31.49 g weight gain and 69.47 and 71.84 g feed intake respectively were recorded in broiler chickens fed T and T . Haematological indices namely: 2 5 PCV, RBC, WBC and Hb were not significantly different (P>0.05) but MCV, MCH, MCHC, lymphocytes, heterophil, eosinophil and monocytes differed significantly (P<0.05). Serum biochemical indices namely total protein, albumin, globulin and uric acid were significantly (P<0.05) influenced by the experimental diets. Though, there was no detrimental effect of SOPM and enzyme on production cost as profit was made at all replacement levels of SOPM with and without enzyme treatment, but profit per bird (N) and cost to benefit ratio revealed the superiority of the broiler chickens fed control diet (T ). Based on the results obtained, 0 SOPM can replace maize up to 25 % without posing any deleterious effect on the broiler chickens growth performance, blood parameters and production cost. However, the cost to benefit ratio was compromised with the use of SOPM. 

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