Effects of progestogens used in menopause hormone therapy on the normal breast and benign breast disease in postmenopausal women

Climacteric ◽  
2021 ◽  
pp. 1-10
Author(s):  
C. Rueda Beltz ◽  
A. Rojas Figueroa ◽  
S. Hinestroza Antolinez ◽  
A. Bastidas
Keyword(s):  
Hormone Therapy ◽  
Postmenopausal Women ◽  
Benign Breast Disease ◽  
Breast Disease ◽  
Normal Breast ◽  
Menopause Hormone Therapy

Immunolocalization of estrogen-producing and metabolizing enzymes in benign breast disease: Comparison with normal breast and breast carcinoma

2010 ◽  
Vol 101 (10) ◽  
pp. 2286-2292 ◽  
Author(s):  
Yoshie Sasaki ◽  
Yasuhiro Miki ◽  
Hisashi Hirakawa ◽  
Yoshiaki Onodera ◽  
Kiyoshi Takagi ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Benign Breast Disease ◽  
Breast Disease ◽  
Normal Breast ◽  
Metabolizing Enzymes

Evaluation of the expression levels of nm23-h1 mRNA in primary breast cancer, benign breast disease, axillary lymph nodes and normal breast tissue

Pathology ◽  
1994 ◽  
Vol 26 (4) ◽  
pp. 423-428 ◽  
Author(s):  
Rebecca J. Goodall ◽  
Hugh J.S. Dawkins ◽  
Peter D. Robbins ◽  
Erika Hähnel ◽  
Mohinder Sarna ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Primary Breast Cancer ◽  
Breast Tissue ◽  
Benign Breast Disease ◽  
Normal Breast Tissue ◽  
Breast Disease ◽  
Normal Breast ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph

scholarly journals Climacteric syndrome. A nutritional approach to treatment

2020 ◽  
Vol 3 (3) ◽  
pp. 189-193
Author(s):  
L.V. Saprykina ◽  
◽  
M.R. Narimanova ◽  
D.M. Ibragimova ◽  
◽  
...  
Keyword(s):  
Hormone Therapy ◽  
Postmenopausal Women ◽  
Hormonal Treatment ◽  
Biologically Active ◽  
Climacteric Syndrome ◽  
Protective Effects ◽  
Female Sex Hormones ◽  
Active Supplement ◽  
Almost All ◽  
Menopause Hormone Therapy

Female sex hormones are of crucial importance for a woman’s life. Almost all women over 40 irrespective of their origin or social status begin to experience physical, psychologic, and emotional problems. Menopause hormone therapy (MHT) is considered the most effective option to improve various symptoms of climacteric syndrome. Non-hormonal treatment can be an alternative to MHT to relieve the symptoms of climacteric symptoms in pre- and postmenopausal women, in particular, in contraindications or reluctance to take MHT. The paper addresses recent findings on the effects of soy isoflavones, β-alanine, tryptophan, and vitamins on tissues and the quality of life of pre- and postmenopausal women. Mense® (JC «Akvion»), a biologically active supplement that contains phytoestrogens, vitamins, and amino acids, is characterized by a variety of protective effects in pre- and postmenopausal periods. This biologically active supplement can be recommended for women with the symptoms of climacteric syndrome as a pretreatment during the screening before prescribing MHT, a dietary modification in contraindications or refusal of MHT, and/or an effective component of the complex treatment for climacteric syndrome.KEYWORDS: perimenopause, postmenopause, non-hormonal treatment, menopause hormone therapy, vasomotor symptoms, phytoestrogens, vitamins.FOR CITATION: Saprykina L.V., Narimanova M.R., Ibragimova D.M. Climacteric syndrome. A nutritional approach to treatment. Russian Journal of Woman and Child Health. 2020;3(3):189–193. DOI: 10.32364/2618-8430-2020-3-3-189-193.

Association of breast cancer and diabetes mellitus in Korean postmenopausal women

2020 ◽  
Author(s):  
Boram Kim ◽  
Jee Hye Han ◽  
Hee Yong Kwak ◽  
Kil Young Kwon ◽  
Junghwan Kim
Keyword(s):  
Breast Cancer ◽  
Diabetes Mellitus ◽  
Postmenopausal Women ◽  
Benign Breast Disease ◽  
Breast Disease ◽  
University Hospital ◽  
Control Group ◽  
Breast Clinic ◽  
Cancer Group ◽  
Increased Risk

Abstract Background: Diabetes mellitus has been associated with an increased risk of breast cancer. This association is, however, controversial, and not elucidated in Asia. This study aimed to determine the association between diabetes mellitus and breast cancer risk in Korean women.Methods: This retrospective study included subjects who underwent an ultrasound-localized needle-extracted biopsy to investigate questionable breast findings at the Eulji University Hospital breast clinic in Seoul, Korea, between 2000 and 2019. The medical records of the participants were reviewed to determine their age, diabetic status, and breast pathology findings. The participants were categorized into two groups, namely, the control group, that included those with benign breast disease; and, the breast cancer group. Logistic regression analyses were performed to assess the association between diabetes and breast cancer amongst pre- and post-menopausal participants.Results: A total of 1268 participants were included in this analysis. We found that diabetes was significantly associated with an increased odds of breast cancer (odds ratio [OR] 2.24; 95% confidence interval [CI], 1.76 to 2.84). Additionally, postmenopausal participants (aged ≥ 50 years) showed increased odds for breast cancer (OR 4.32; 95% CI, 3.37 to 5.53). The association between diabetes and breast cancer was significant, after adjusting for age, in the postmenopausal group (adjusted OR [aOR] 1.60; 95% CI, 1.09 to 2.35), but was not significant in the premenopausal group (aOR 1.10; 95% CI, 0.76 to 1.60).Conclusion: Diabetes was associated with increased odds of breast cancer compared to benign breast disease in postmenopausal women in Korea.

Prostate specific antigen in breast cancer, benign breast disease and normal breast tissue

1996 ◽  
Vol 40 (2) ◽  
pp. 171-178 ◽  
Author(s):  
He Yu ◽  
Eleftherios P. Diamandis ◽  
Michael Levesque ◽  
Maurizia Giai ◽  
Riccardo Roagna ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prostate Specific Antigen ◽  
Breast Tissue ◽  
Benign Breast Disease ◽  
Normal Breast Tissue ◽  
Specific Antigen ◽  
Breast Disease ◽  
Normal Breast

scholarly journals SARS-Cov-2 Infection in Postmenopausal Women. New Data on Menopause Hormone Therapy

2022 ◽  
Author(s):  
Laura Baquedano ◽  
Javier Navarro ◽  
Yasmina José ◽  
Alexander Tristancho ◽  
Ana Ruiz ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Hospital Admission ◽  
Hormone Therapy ◽  
Postmenopausal Women ◽  
Protective Factor ◽  
Positive Impact ◽  
Respiratory Disorders ◽  
The Mean ◽  
Menopause Hormone Therapy

Abstract ObjectiveTo address the factors involved in hospital admission and medical follow up in postmenopausal women with COVID-19 diagnosis.MethodsRetrospective observational study. Postmenopausal women aged between 40-70 years since September 2020 until June 2021 with COVID-19 diagnosis were included. Of the 300 women cohort, 50 were receiving menopause hormone therapy (MHT)Results 288 patients were analyzed. The mean age was 56.20 years (+/-6.06y SD). Age (p=0.030), High blood pressure (HBP) (p=0.002), respiratory disorders (p=0.003), depression (p=0.028) and fibromyalgia (p=0.030) were associated with a greater risk for hospital admission, while MHT was found as a protective factor (p=0.042). Being a health professional (p<0.001), HBP (p=0.029), respiratory disorders (p=0.022), vitamin D deficiency (p=0.010), depression (p=0.005) and fibromyalgia (p=0.001) were related with a longer follow up while MHT was related with a shorter one (p=0.010). Regression analysis showed that HBP and respiratory disorders acted as independent factors for hospital admission while MHT and fibromyalgia were for the length of follow up. ConclusionsMHT has a positive impact in postmenopausal women with SARS-CoV-2 infection. HBP and respiratory disorders are associated with a higher risk of hospital admission of these patients.

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