Recent developments in pharmacotherapy for hypertriglyceridemia: what’s the current state of the art?

2019 ◽  
Vol 21 (1) ◽  
pp. 107-120 ◽  
Author(s):  
Matilda Florentin ◽  
Michael S Kostapanos ◽  
Panagiotis Anagnostis ◽  
George Liamis
Keyword(s):  
State Of The Art ◽  
Current State ◽  
Recent Developments

A physiome standards-based model publication paradigm

2009 ◽  
Vol 367 (1895) ◽  
pp. 1823-1844 ◽  
Author(s):  
David P. Nickerson ◽  
Martin L. Buist
Keyword(s):  
Mathematical Models ◽  
State Of The Art ◽  
Web Browsers ◽  
New Paradigm ◽  
Broadband Internet ◽  
Cellular Electrophysiology ◽  
Current State ◽  
Recent Developments ◽  
Systems Biology Markup Language ◽  
Model Publication

In this era of widespread broadband Internet penetration and powerful Web browsers on most desktops, a shift in the publication paradigm for physiome-style models is envisaged. No longer will model authors simply submit an essentially textural description of the development and behaviour of their model. Rather, they will submit a complete working implementation of the model encoded and annotated according to the various standards adopted by the physiome project, accompanied by a traditional human-readable summary of the key scientific goals and outcomes of the work. While the final published, peer-reviewed article will look little different to the reader, in this new paradigm, both reviewers and readers will be able to interact with, use and extend the models in ways that are not currently possible. Here, we review recent developments that are laying the foundations for this new model publication paradigm. Initial developments have focused on the publication of mathematical models of cellular electrophysiology, using technology based on a CellML- or Systems Biology Markup Language (SBML)-encoded implementation of the mathematical models. Here, we review the current state of the art and what needs to be done before such a model publication becomes commonplace.

scholarly journals Ambient Air Quality and Human Health: Current Concepts—Part 1

1995 ◽  
Vol 2 (4) ◽  
pp. 211-222 ◽  
Author(s):  
Tee L Guidotti
Keyword(s):  
Air Quality ◽  
Human Health ◽  
State Of The Art ◽  
Respiratory Health ◽  
Quality Standards ◽  
Ambient Air ◽  
Ambient Air Quality ◽  
Air Quality Standards ◽  
Current State ◽  
Recent Developments

There is a fundamental reevaluation of the association between air quality and human health taking place. This reevaluation is motivated by several recent developments: increasing interest in air quality as an environmental issue; interest in the unanswered questions regarding the epidemiology of asthma; and the reduced prevalence of the principal hazard to respiratory health, cigarette smoking, the control of which invites interest in second-order determinants of health. This article attempts to provide a framework for understanding air quality issues that pertain to human health. The objective is to provide the specialist in respiratory medicine with an overview that will assist in educating patients and in responding to their inquiries, and to equip the physician to respond to requests for assistance or interpretation when called upon to comment on public policy issues involving air pollution. The implications of setting air quality standards or objectives to meet arbitrary levels of risk of health effects are examined. The current state of the art does not support risk-based air quality standards. A policy of continuous improvement is most protective of both human health and the environment.

scholarly journals A Review of Recent Developments in Molecular Dynamics Simulations of the Photoelectrochemical Water Splitting Process

Catalysts ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 807
Author(s):  
Nicolae Goga ◽  
Leonhard Mayrhofer ◽  
Ionut Tranca ◽  
Silvia Nedea ◽  
Koen Heijmans ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Water Splitting ◽  
State Of The Art ◽  
Special Focus ◽  
Semiconductor Interfaces ◽  
Current State ◽  
Recent Developments ◽  
Dynamics Simulations ◽  
Photoelectrochemical Hydrogen Production ◽  
Splitting Process

In this review, we provide a short overview of the Molecular Dynamics (MD) method and how it can be used to model the water splitting process in photoelectrochemical hydrogen production. We cover classical non-reactive and reactive MD techniques as well as multiscale extensions combining classical MD with quantum chemical and continuum methods. Selected examples of MD investigations of various aqueous semiconductor interfaces with a special focus on TiO2 are discussed. Finally, we identify gaps in the current state-of-the-art where further developments will be needed for better utilization of MD techniques in the field of water splitting.

scholarly journals State-of-the-Art of Artificial Intelligence

2021 ◽  
Author(s):  
Ramjee Prasad ◽  
Purva Choudhary
Keyword(s):  
Artificial Intelligence ◽  
Big Data ◽  
State Of The Art ◽  
Turing Test ◽  
Rapid Progress ◽  
Current State ◽  
Recent Developments ◽  
Historical Developments ◽  
Insight Into ◽  
Made In

Artificial Intelligence (AI) as a technology has existed for less than a century. In spite of this, it has managed to achieve great strides. The rapid progress made in this field has aroused the curiosity of many technologists around the globe and many companies across various domains are curious to explore its potential. For a field that has achieved so much in such a short duration, it is imperative that people who aim to work in Artificial Intelligence, study its origins, recent developments, and future possibilities of expansion to gain a better insight into the field. This paper encapsulates the notable progress made in Artificial Intelligence starting from its conceptualization to its current state and future possibilities, in various fields. It covers concepts like a Turing machine, Turing test, historical developments in Artificial Intelligence, expert systems, big data, robotics, current developments in Artificial Intelligence across various fields, and future possibilities of exploration.

Electrochemical immunosensors, genosensors and phagosensors for Salmonella detection

2014 ◽  
Vol 6 (22) ◽  
pp. 8858-8873 ◽  
Author(s):  
Susana Liébana ◽  
Delfina Brandão ◽  
Salvador Alegret ◽  
María Isabel Pividori
Keyword(s):  
State Of The Art ◽  
Detection Methods ◽  
Current State ◽  
Electrochemical Immunosensors ◽  
Recent Developments

This review discusses the current state of the artSalmonelladetection methods. In this perspective, emphasis is given to the recent developments in biosensors, in particular electrochemical immunosensors, genosensors and phagosensors.

scholarly journals Perspectives on the future of multi-dimensional platforms

2019 ◽  
Vol 218 ◽  
pp. 72-100 ◽  
Author(s):  
Gino Groeneveld ◽  
Bob W. J. Pirok ◽  
Peter J. Schoenmakers
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
High Resolution ◽  
High Resolution Mass Spectrometry ◽  
State Of The Art ◽  
Two Dimensional ◽  
Current State ◽  
Recent Developments ◽  
Resolution Mass

A practical example, the characterization of polysorbates by high-resolution comprehensive two-dimensional liquid chromatography in combination with high-resolution mass spectrometry, is described as a culmination of recent developments in 2D-LC and as an illustration of the current state of the art.

Recent Developments in Titanium

1966 ◽  
Vol 70 (668) ◽  
pp. 777-781 ◽  
Author(s):  
H. W. Shaw
Keyword(s):  
State Of The Art ◽  
New Products ◽  
Alloy Development ◽  
Current State ◽  
Recent Developments

The intention in presenting this paper is to outline the main trends in recent alloy development and to indicate the current state of the art as far as the user is concerned, particularly on the behaviour of the new products in the problem areas so designated by the engineering metallurgists and materials specialists in the industry.In reviewing recent alloy development it is convenient to identify two main lines in terms of the metallurgical structures involved, since these tend to define the more appropriate areas for design interest.

scholarly journals Magnesium batteries: Current state of the art, issues and future perspectives

2014 ◽  
Vol 5 ◽  
pp. 1291-1311 ◽  
Author(s):  
Rana Mohtadi ◽  
Fuminori Mizuno
Keyword(s):  
State Of The Art ◽  
Full Potential ◽  
Research Groups ◽  
Magnesium Battery ◽  
The Past ◽  
Current State ◽  
Innovative Solutions ◽  
Fundamental Understanding ◽  
Recent Developments ◽  
Core Components

“...each metal has a certain power, which is different from metal to metal, of setting the electric fluid in motion...” Count Alessandro Volta. Inspired by the first rechargeable magnesium battery prototype at the dawn of the 21st century, several research groups have embarked on a quest to realize its full potential. Despite the technical accomplishments made thus far, challenges, on the material level, hamper the realization of a practical rechargeable magnesium battery. These are marked by the absence of practical cathodes, appropriate electrolytes and extremely sluggish reaction kinetics. Over the past few years, an increased interest in this technology has resulted in new promising materials and innovative approaches aiming to overcome the existing hurdles. Nonetheless, the current challenges call for further dedicated research efforts encompassing fundamental understanding of the core components and how they interact with each other to offering new innovative solutions. In this review, we seek to highlight the most recent developments made and offer our perspectives on how to overcome some of the remaining challenges.

scholarly journals The Equivalent Circuit Approach for the Electrical Diagnostics of Dielectric Barrier Discharges: The Classical Theory and Recent Developments

Atoms ◽  
2019 ◽  
Vol 7 (1) ◽  
pp. 14 ◽  
Author(s):  
Andrei Pipa ◽  
Ronny Brandenburg
Keyword(s):  
Equivalent Circuit ◽  
State Of The Art ◽  
Dielectric Barrier Discharges ◽  
Dielectric Barrier ◽  
Stage Of Development ◽  
Current State ◽  
Recent Developments ◽  
Reactor Geometry ◽  
Electrical Diagnostics ◽  
Barrier Discharges

Measurements of current and voltage are the basic diagnostics for electrical discharges. However, in the case of dielectric barrier discharges (DBDs), the measured current and voltage waveforms are influenced by the discharge reactor geometry, and thus, interpretation of measured quantities is required to determine the discharge properties. This contribution presents the main stages of the development of electrical diagnostics of DBDs, which are based on lumped electrical elements. The compilation and revision of the contributions to the equivalent circuit approach are targeted to indicate: (1) the interconnection between the stage of development, (2) its applicability, and (3) the current state-of-the-art of this approach.

scholarly journals Food Informatics—Review of the Current State-of-the-Art, Revised Definition, and Classification into the Research Landscape

Foods ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 2889
Author(s):  
Christian Krupitzer ◽  
Anthony Stein
Keyword(s):  
Precision Agriculture ◽  
Food Production ◽  
State Of The Art ◽  
Research Perspectives ◽  
Current State ◽  
Industrial Iot ◽  
Recent Developments ◽  
Data Driven Approach ◽  
New Perspective ◽  
Definition Of

Background: The increasing population of humans, changing food consumption behavior, as well as the recent developments in the awareness for food sustainability, lead to new challenges for the production of food. Advances in the Internet of Things (IoT) and Artificial Intelligence (AI) technology, including Machine Learning and data analytics, might help to account for these challenges. Scope and Approach: Several research perspectives, among them Precision Agriculture, Industrial IoT, Internet of Food, or Smart Health, already provide new opportunities through digitalization. In this paper, we review the current state-of-the-art of the mentioned concepts. An additional concept is Food Informatics, which so far is mostly recognized as a mainly data-driven approach to support the production of food. In this review paper, we propose and discuss a new perspective for the concept of Food Informatics as a supportive discipline that subsumes the incorporation of information technology, mainly IoT and AI, in order to support the variety of aspects tangent to the food production process and delineate it from other, existing research streams in the domain. Key Findings and Conclusions: Many different concepts related to the digitalization in food science overlap. Further, Food Informatics is vaguely defined. In this paper, we provide a clear definition of Food Informatics and delineate it from related concepts. We corroborate our new perspective on Food Informatics by presenting several case studies about how it can support the food production as well as the intermediate steps until its consumption, and further describe its integration with related concepts.

Sign in / Sign up

Export Citation Format

Share Document