scholarly journals Characteristics of Water-soluble Polysaccharides Extracts Produced from Perilla Seed Meal via Enzymatic Hydrolysis

2020 ◽  
Vol 18 (1) ◽  
pp. 653-661
Author(s):  
Yeo Jin Hwang ◽  
Ja Min Kim ◽  
Kyung Young Yoon
Keyword(s):  
Enzymatic Hydrolysis ◽  
Water Soluble ◽  
Seed Meal ◽  
Perilla Seed

scholarly journals Biological activity of enzymatic hydrolysates and the membrane ultrafiltration fractions from perilla seed meal protein

2019 ◽  
Vol 37 (No. 3) ◽  
pp. 180-185 ◽  
Author(s):  
Bo Yeon Park ◽  
Kyung Young Yoon
Keyword(s):  
Inhibitory Activity ◽  
Physiological Activity ◽  
Seed Meal ◽  
Angiotensin I ◽  
Food Material ◽  
Molecular Weights ◽  
Chelating Activity ◽  
Angiotensin I Converting Enzyme ◽  
Meal Protein ◽  
Perilla Seed

The Perilla seed meal (PSM) protein was hydrolyzed with Flavourzyme; the hydrolysate was fractionated by an ultrafiltration and its physiological activity was measured. Peptides with low molecular weights exhibited higher antioxidant activity, except for the Fe<sup>2+</sup> chelating activity, compared to peptides with a high molecular weight. The IC<sub>50</sub> values of the α-amylase inhibitory activity ranged from 727.89 µg/ml to 757.18 µg/ml, the α-glucosidase inhibitory activity was highest in the &lt; 1 kDa fraction. The &lt; 1 kDa fraction exhibited the strongest angiotensin I-converting enzyme inhibitory activity. As a result, the peptides from PSM protein hydrolysates, particularly peptides &lt; 1 kDa, exhibited excellent antioxidant, antidiabetic, and antihypertensive activities and thus were highly likely to be developed as a functional food material.

scholarly journals Protective Effects of Unsaponifiable Matter from Perilla Seed Meal on UVB-induced Damages and the Underlying Mechanisms in Human Skin Fibroblasts

Antioxidants ◽  
2019 ◽  
Vol 8 (12) ◽  
pp. 644 ◽  
Author(s):  
Hana Lee ◽  
Jeehye Sung ◽  
Younghwa Kim ◽  
Heon Sang Jeong ◽  
Junsoo Lee
Keyword(s):  
Unsaponifiable Matter ◽  
Transforming Growth Factor Beta ◽  
Collagen Synthesis ◽  
Transforming Growth Factor ◽  
Skin Aging ◽  
Seed Meal ◽  
Activator Protein 1 ◽  
Protective Effects ◽  
Uvb Exposure ◽  
Perilla Seed

Unsaponifiable matter (USM) from perilla seed meal contains numerous phytochemicals, including tocopherols, phytosterols, squalene, and policosanols, that exhibit antioxidant and health-promoting properties. In this study, the protective effects of USM on UVB-induced skin aging were investigated in Hs68 cells. UVB irradiation decreased cell viability by 26% compared to the control. However, USM blocked UVB-induced cytotoxicity. Moreover, USM treatment significantly decreased the UVB-induced production of reactive oxygen species and attenuated the UVB-induced production and mRNA expression of matrix metalloproteinases (MMPs) by inhibiting the phosphorylation of mitogen-activated protein kinases and activator protein 1 (AP-1). Furthermore, UVB exposure led to a 49.4% reduction in collagen synthesis. However, USM treatment restored collagen synthesis through upregulation of the transforming growth factor beta (TGF-β)/Smad2/3 pathways. These data indicate that USM regulates the production of MMPs and collagen by modulation of the TGF-β/Smad pathway and AP-1 activity, suggesting that USM may be a useful anti-photoaging ingredient.

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