Purification and partial characterization of the nephritis strain-associated protein from Streptococcus pyogenes, group A.
1986 ◽
Vol 163
(3)
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pp. 697-712
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Keyword(s):
Group A
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We report the isolation and purification of the nephritis strain-associated protein (NSAP) first described by Villareal et al. (8). Amino acid analysis, and determination of the first 21 amino-terminal amino acids indicated that this 46 kD protein is a streptokinase. Biochemical analysis confirmed that NSAP could act as a plasminogen activator; immunological investigations indicated that NSAP is antigenically different from streptokinase from group C streptococcus, and possibly represents a unique streptokinase. It is this uniqueness that may contribute to the role of NSAP in the pathogenesis of acute poststreptococcal glomerulonephritis.
2000 ◽
Vol 68
(3)
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pp. 1019-1025
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Keyword(s):
2015 ◽
Vol 58
(4)
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pp. 1776-1794
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2001 ◽
Vol 67
(2)
◽
pp. 733-741
◽
2004 ◽
Vol 15
(7)
◽
pp. 1785-1793
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Keyword(s):