scholarly journals Risk analysis and solution of using graphene: Material, synthesis, and application (Mini review)

2021 ◽  
Vol 926 (1) ◽  
pp. 012054
Author(s):  
L Destiarti ◽  
I Kartini ◽  
Riyanto ◽  
Roto ◽  
Mudasir

Abstract Graphene is a nanomaterial with unique physical and chemical properties. The two-dimensional hexagonal sp2 structure in the honeycomb lattice has high thermal conductivity, high electricity, mechanical strength, and large surface area. The nano properties are significantly different from the bulk material. The review of the material, synthesis and application aspects of graphene gave rise to risk analysis in each field of study. Graphene material does not yet have adequate information regarding the risk of danger. Because graphene is nano-sized, this material can enter the human body through inhalation, ocular, cutaneous and oral. Graphene synthesis involves using chemicals that will produce hazardous products and reduce agents with high toxicity. The risk becomes more and more when the challenges of mass production of graphene are faced. Graphene can be applied as sensors, nanoelectronics, and biomedical applications. In this biomedical application, graphene has direct contact with humans and can increase reactive oxygen species in the body. The recommendation to overcome the risk is to use personal protective equipment and handle graphene material properly. The toxic materials involve in the synthesis step can be replaced with other environmentally friendly materials. Antidotes substances can reduce the toxicity of graphene materials so that the risks graphene in its application can be overcome.

Author(s):  
O.G. Drugova ◽  
◽  
A.A. Fedoruk ◽  
T.N. Shtin

Abstract. Due to the predominance of PM1 particles in the air samples, the following metals were found in the aerosol: copper, zinc, silicon, iron, lead, sulfur, arsenic, aluminum, antimony, tin, magnesium, cadmium and several other metals. The content of sulfates was significantly noted. These physical and chemical properties show a considerable toxic potential of industrial aerosol. The MPC of lead, sulfur and silicon dioxides, as well as nitrogen oxides and formaldehyde were detected in the working air. Meanwhile, copper, zinc, and iron did not exceed their MPC. Moreover, an underestimation of the aerosol was observed within the framework of industrial control. It has been found that the aerosol components may have an irritating, reprotoxic, allergenic, and carcinogenic effect on the body. Further consideration of the dispersed and chemical composition of the aerosol is required to determine the concentration of identified substances in the working air and the limiting components determining its biological effect.


2015 ◽  
Vol 19 (2) ◽  
pp. 39-50
Author(s):  
Inna Tiurikova ◽  
Mykhailo Peresichnyi

Abstract The results of studies in the field of beverage functionality using walnut are presented. The main components such as celery, Jerusalem artichokes, carrots, pumpkin and rhubarb, as a dietary supplement - extracts from walnut of milk-maturity stage are offered for creating blends. The basic physical and chemical properties of fruit and vegetable raw materials and semi-finished products created on the base of them have been studied, and their nutritional and biological value has been proved. Rational technologies of fruit and vegetable blends with nut additives have been identified. Their biological value has been confirmed. Drinks are recommended for use in the daily diet of human beings to satisfy thirst and enrich the body by biologically valuable components.


2014 ◽  
Vol 675-677 ◽  
pp. 325-328
Author(s):  
Jun Zhang ◽  
Jian Guo Lin ◽  
Han Zhang

By investigating and analyzing PX demand in recent years and the distribution of PX projects in Dagushan chemical industrial park, combining its physical and chemical properties and marine environment near Dalian Dagushan, aim to make environmental assessments on the damage caused by PX to the marine environment and propose appropriate emergency measures.


Nanomedicine ◽  
2019 ◽  
Vol 14 (20) ◽  
pp. 2763-2775 ◽  
Author(s):  
Fatih Zor ◽  
Fatma Nurefsan Selek ◽  
Giuseppe Orlando ◽  
David F Williams

Biocompatibility is a very common word that is used within biomaterial science and used for description of the interactions between the foreign material and the body. However, the meaning of biocompatibility as well as the mechanisms that collectively constitutes is still unclear. With the advance of nanotechnology, new concerns have been observed related to biocompatibility of these biomaterials. Due to their small size and variability of their physical and chemical properties, nanoparticles’ (NP) distribution within the body and interactions with the target cells and tissues are highly variable. Here, we tried to provide an overview about NPs, the concept of biocompatibility and biocompatibility-related issues in nanomedicine and several different NPs.


2015 ◽  
Vol 66 (2) ◽  
pp. 97-108 ◽  
Author(s):  
Veno Kononenko ◽  
Mojca Narat ◽  
Damjana Drobne

Abstract When nanoparticles enter the body, their interactions with cells are almost unavoidable. Unintended nanoparticle interaction with immune cells may elicit a molecular response that can have toxic effects and lead to greater susceptibility to infectious diseases, autoimmune disorders, and cancer development. As evidenced by several studies, nanoparticle interactions with biological systems can stimulate inflammatory or allergic reactions and activate the complement system. Nanoparticles can also stimulate immune response by acting as adjuvants or as haptens. Immunosuppressive effects have also been reported. This article gives a brief review of in vitro and in vivo research evidencing stimulatory or suppressive effects of nanoparticles on the immune system of mammals. In order to ensure safe use of nanosized particles, future research should focus on how their physical and chemical properties influence their behaviour in the biological environment, as they not only greatly affect nanoparticle-immune system interactions but can also interfere with experimental assays


2021 ◽  
Vol 14 (2) ◽  
pp. 48-55
Author(s):  
C. N. Buzdalkin ◽  
N. G. Vlasova ◽  
A. V. Rozhko ◽  
V. N. Bortnovsky

The Republican Research Center for Radiation Medicine and Human Ecology in the Internal and External Emergency Plans of the Belarusian nuclear power plant is specified as an institution that provides specialized treatment for personnel, as well as persons from the population living in the emergency zone of the station. The plant is the first facility in the Republic that used nuclear energy. There is no experience in treating radiation injuries in Belarus. This is the first time that the National Health Service has been assigned the task of ensuring readiness for the reception and specialized treatment of people who have been exposed to emergency or unplanned radiation. The purpose of the work is to establish criteria for radiation exposure for use in a Belarusian specialized medical institution in case of medical response to radiological accidents. As a result of the analysis of publications of international organizations, the criteria of radiation exposure that can be applied in the conditions of Belarusian specialized medical institutions were selected. Assessment of the criteria was made taking into account existing national technical regulations and the available capabilities of emergency response participants. To account for the quality of radiation in relation to deterministic effects “Gy-equivalent” is used. The criteria include both dosimetric values for cases of external and internal accidental and unplanned exposure, and levels of radioactive substances with unknown physical and chemical properties entering the body that require urgent medical intervention. Criteria for cases of surface contamination of skin and wounds require separate consideration.


2021 ◽  
Vol 15 (1) ◽  
pp. 055-062
Author(s):  
Aliyu Haruna Sani ◽  
Musa Amanabo

Heavy metal toxicity over the years has been proven to be a source of diverse health risks. Thou these metals, play certain biological roles, they are in excess amount get accumulated in the body and food chain displaying a chronic effect in the long run. Lead toxicity is an important environmental disease and its effects on the human body are devastating with its toxicity dependent upon the absorbed dose, the route of exposure as well as the duration of exposure. There is almost no function in the human body which is not affected by lead toxicity. Lead is highly persistent in the environment and because of its continuous use, its levels rise in almost every country particularly in developing countries like Nigeria where it occupies unique physical and chemical properties that make it suitable for a large number of applications. Various public health measures have been undertaken to control, prevent and treat lead toxicity occurring at various levels, such as occupational exposure, accidents and environmental factors. This article reviews the works listed in scientific literatures with recent updates regarding the toxicity of lead. Focus is also on the biomarkers of lead toxicity on the renal, hematological and oxidative stress conditions.


2021 ◽  
Vol 2 (10) ◽  
pp. 977-984
Author(s):  
Divya Chauhan ◽  
Mohammad Ashfaq ◽  
Neetu Talreja ◽  
Ramalinga Viswanathan Managalraja

Recently 2D materials are booming in the field of energy, environment, and biomedical application. Incorporation of metal/non-metal within 2D materials significantly influences the physical and chemical properties, making them intriguing materials for various applications. The advancement of 2D material requires strategic modification by manipulating the electronic structure, which remains a challenge. Herein, we describe 2D materials for the environment, energy, and biomedical application. A predominant aim of this short communication is to summarize the literature on the advanced environment, energy, and biomedical application (especially COVID-19).


2009 ◽  
Vol 83-86 ◽  
pp. 953-958
Author(s):  
Ching Yen Ho ◽  
Yu Hsiang Tsai ◽  
Mao Yu Wen

Nanometer-sized particles possess characteristic physical and chemical properties different from those of bulk materials due to an increase in surface-to-volume ratios as well as of confinement of electrons, excitons, and photons into small volumes. Therefore it is worthwhile to discuss the thermal behaviours of powders constituted by nanometer-sized particles. The heat transfer in the powder composed of nanoparticles is experimentally investigated in this paper. The understanding for thermal properties of the powder is advantageous to the advancement of the processing technologies such as laser cladding, laser sintering, powder metallurgy and its other applications. The powder is wrapped up in the slender tube made of insulating material. One end of the slender tube filled with powder is maintained at temperature 0°C and the other end is kept at room temperature. The temperature histories at two different locations in the slender tube are recorded using thermal couples. The results show that the thermal diffusivity in the powder composed of nanoparticles is larger than that in bulk material. The pressure on the Al powders enhances the rate of heat transport due to the increase of contact area for thermal conduction.


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