scholarly journals Review of digital PCR potential for surveillance of emerging disease from wastewater

2021 ◽  
Vol 926 (1) ◽  
pp. 012065
Author(s):  
A Dewantoro ◽  
W C Anggundari ◽  
B Prasetya ◽  
Yopi
Keyword(s):  
Nucleic Acid ◽  
Infectious Diseases ◽  
Disease Transmission ◽  
Emerging Infectious Diseases ◽  
Digital Pcr ◽  
Absolute Quantification ◽  
Emerging Disease ◽  
Environmental Surveillance ◽  
The World

Abstract Emerging infectious diseases (EID) such as COVID-19 had been widely caused massive impact for all countries in the world. The spreading of pathogens became uncontrolled and unpredictable to overcome this pandemic disease. Some non-waterborne EID also was discovered in wastewater in many countries of the world. Studies showed that digital PCR could become a powerful tool for environmental surveillance. It enables the performance of absolute quantification for nucleic acid with a high inhibitory sample, like wastewater, and potentially possibly detected a tiny quantity of pathogen residue and tracked the infectious diseases that originated from human excretions into sewage. Hopefully, with the development of this method and support of measurement and standardization, it is possible to become an effective method to overcome the digital PCR (dPCR) method challenge for surveillance of disease transmission from wastewater.

scholarly journals Human factors in emerging infectious diseases

2021 ◽  
Vol 2 (1) ◽  
pp. 21-29 ◽  
Author(s):  
Scott B. Halstead
Keyword(s):  
Infectious Disease ◽  
Infectious Diseases ◽  
Human Factors ◽  
Emerging Infectious Diseases ◽  
Emerging Infectious Disease ◽  
Emerging Disease ◽  
Human Behaviour ◽  
Microbial World ◽  
Underlying Causes ◽  
Methods Of Control

When the underlying causes and mechanisms of emerging infectious disease problems are studied carefully, human behaviour is often involved. Even more often, the only methods of control or prevention available are to change human behaviour. Several major recent emerging disease problems can be cited. It is sometimes emphasized that it is human carelessness, human excesses, human ignorance or human habits of conquest or leisure which contribute directly to the biological niches that microorganisms are all too capable of exploiting. We must look at ourselves as the engines of microbial opportunism. It is not likely that we will ever conquer the microbial world;we must look instead to control the human factors that contribute to emergence.

Consistent Infection Prevention: Vital During Routine and Emerging Infectious Diseases Care

2017 ◽  
Vol 22 (1) ◽  
Author(s):  
Terri Rebmann ◽  
Ruth Carrico
Keyword(s):  
Infectious Diseases ◽  
Disease Transmission ◽  
Infection Prevention ◽  
Healthcare Providers ◽  
Emerging Infectious Diseases ◽  
Occupational Exposures ◽  
The United States ◽  
Vital Role ◽  
Routine Practice ◽  
Adequate Knowledge

Emerging infectious diseases impact healthcare providers in the United States and globally. Nurses play a vital role in protecting the health of patients, visitors, and fellow staff members during routine practice and biological disasters, such as bioterrorism, pandemics, or outbreaks of emerging infectious diseases. One vital nursing practice is proper infection prevention procedures. Failure to practice correctly and consistently can result in occupational exposures or disease transmission. This article reviews occupational health risks, and pharmacological and nonpharmacological interventions for nurses who provide care to patients with new or re-emerging infectious diseases. Infection prevention education based on existing infection prevention competencies is critical to ensure adequate knowledge and safe practice both every day and in times of limited resources. Challenges specific to infectious disease disasters are discussed, as well as the role of microorganisms and nurse education for infection prevention.

scholarly journals From People to Panthera: Natural SARS-CoV-2 Infection in Tigers and Lions at the Bronx Zoo

mBio ◽  
2020 ◽  
Vol 11 (5) ◽  
Author(s):  
Denise McAloose ◽  
Melissa Laverack ◽  
Leyi Wang ◽  
Mary Lea Killian ◽  
Leonardo C. Caserta ◽  
...  
Keyword(s):  
United States ◽  
Severe Acute Respiratory Syndrome ◽  
Disease Transmission ◽  
Emerging Infectious Diseases ◽  
Genomic Data ◽  
The United States ◽  
Cellular Damage ◽  
Animal Reservoir ◽  
Live Virus ◽  
The World

ABSTRACT Despite numerous barriers to transmission, zoonoses are the major cause of emerging infectious diseases in humans. Among these, severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and ebolaviruses have killed thousands; the human immunodeficiency virus (HIV) has killed millions. Zoonoses and human-to-animal cross-species transmission are driven by human actions and have important management, conservation, and public health implications. The current SARS-CoV-2 pandemic, which presumably originated from an animal reservoir, has killed more than half a million people around the world and cases continue to rise. In March 2020, New York City was a global epicenter for SARS-CoV-2 infections. During this time, four tigers and three lions at the Bronx Zoo, NY, developed mild, abnormal respiratory signs. We detected SARS-CoV-2 RNA in respiratory secretions and/or feces from all seven animals, live virus in three, and colocalized viral RNA with cellular damage in one. We produced nine whole SARS-CoV-2 genomes from the animals and keepers and identified different SARS-CoV-2 genotypes in the tigers and lions. Epidemiologic and genomic data indicated human-to-tiger transmission. These were the first confirmed cases of natural SARS-CoV-2 animal infections in the United States and the first in nondomestic species in the world. We highlight disease transmission at a nontraditional interface and provide information that contributes to understanding SARS-CoV-2 transmission across species. IMPORTANCE The human-animal-environment interface of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important aspect of the coronavirus disease 2019 (COVID-19) pandemic that requires robust One Health-based investigations. Despite this, few reports describe natural infections in animals or directly link them to human infections using genomic data. In the present study, we describe the first cases of natural SARS-CoV-2 infection in tigers and lions in the United States and provide epidemiological and genetic evidence for human-to-animal transmission of the virus. Our data show that tigers and lions were infected with different genotypes of SARS-CoV-2, indicating two independent transmission events to the animals. Importantly, infected animals shed infectious virus in respiratory secretions and feces. A better understanding of the susceptibility of animal species to SARS-CoV-2 may help to elucidate transmission mechanisms and identify potential reservoirs and sources of infection that are important in both animal and human health.

Emerging and Reemerging Infectious Diseases - Past, Present and Future

2007 ◽  
Vol 2 (2) ◽  
pp. 66-70 ◽  
Author(s):  
Yoshifumi Takeda ◽  
Keyword(s):  
Infectious Diseases ◽  
Emerging Infectious Diseases ◽  
World Health ◽  
Control Law ◽  
Global Response ◽  
The Us ◽  
The World ◽  
Us Government ◽  
Health Organization ◽  
Global Threat

The global threat of new infectious diseases first became widely recognized in the 1990s. The US government published a report on emerging and reemerging infectious diseases followed by the World Health Organization (WHO), which adopted the slogan "Emerging Infectious Diseases: Global Alert, Global Response" in 1997. Typical examples of the more than 30 infectious diseases emerging since 1970s are HIV/AIDS, Vibrio cholerae O139 infection, enterohemorrhagic Escherichia coli infection, severe acute respiratory syndrome (SARS), and avian influenza. The New Infectious Diseases Control Law enacted in Japan in 1999 was to control these emerging infectious diseases and the already existing ones.

scholarly journals SIR Mathematical Model of Convalescent Plasma Transfusion Applied to the COVID-19 Pandemic Data in Indonesia to Control the Spread of the Disease

2021 ◽  
Vol 2084 (1) ◽  
pp. 012022
Author(s):  
Hennie Husniah ◽  
Ruhanda ◽  
Asep Kuswandi Supriatna
Keyword(s):  
Mathematical Model ◽  
Infectious Diseases ◽  
Disease Transmission ◽  
Emerging Infectious Diseases ◽  
Mortality Rates ◽  
Sir Model ◽  
Difficult Problem ◽  
Plasma Transfusion ◽  
Preventive Actions ◽  
Discrete Mathematical Model

Abstract In this paper we develop a mathematical model of disease transmission dynamics. Although some vaccines for some infectious diseases are available, there are some cases where handling new emerging infectious diseases, such as COVID-19 pandemic, is still a difficult problem to handle. Preventive actions, such as wearing masks, distance guarding, frequent hand washing, and others are still the most important interventions in handling the transmission of this disease. Recently, several countries have allowed the use of convalescent plasma transfusion (CPT) in the management of moderate and severe COVID-19 patients. Several early studies of this use have yielded prospective results with reduced mortality rates. A recent work also shows that using a simple discrete mathematical model of CPT could reduce the outbreak of disease transmission, in the sense of reducing the peak number of active cases and the length of the outbreak itself. In this paper, we use a continuous SIR model applied to COVID-19 pandemic data in Indonesia to address an important question whether convalescent plasma transfusion may reduce the transmission of the disease.

THE OVERVIEW OF EPIZOOTIOLOGIC SITUATION OF EQUIDS AND RUMINANTS IN MONGOLIA

2018 ◽  
Vol 21 (02) ◽  
pp. 9-16
Author(s):  
Khatanbaatar I ◽  
V Skotakova ◽  
Byambarenchin B ◽  
Batsukh Z ◽  
Battsetseg G ◽  
...  
Keyword(s):  
Global Change ◽  
Infectious Diseases ◽  
Labour Force ◽  
Emerging Infectious Diseases ◽  
Animal Origin ◽  
Zoonotic Potential ◽  
Wide Spread ◽  
The World

Ecological inbalance, global change, new mode of lifestyle and increasing population cause the spread of zoonotic infectious diseases around the world and re-emergence disease among many others. The aim of this article is to summarize the situation of the important infectious diseases of the ruminants and horses in Mongolia. Some of these diseases have zoonotic potential, too. Livestock in Mongolia is an irreplaceable source of livelihood, labour force, means of transport, subsistence and companion as well as important component of the culture in this part of world. However, due to the wide-spread of these animals they also serve as a host and vector for many dangerous infectious diseases. Our overview focuses on the most important infectious diseases,mainly zoonoses in Mongolia and its current epizootologic status. People may be infected during contact with infected animals, though a more frequent path of infection is via foodstuffs of animal origin. Re-emerging infectious diseases are diseases that are already familiar to us and their increased occurrence is associated with a change in the process of transmission of infection.

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