scholarly journals From People to Panthera: Natural SARS-CoV-2 Infection in Tigers and Lions at the Bronx Zoo

mBio ◽  
2020 ◽  
Vol 11 (5) ◽  
Author(s):  
Denise McAloose ◽  
Melissa Laverack ◽  
Leyi Wang ◽  
Mary Lea Killian ◽  
Leonardo C. Caserta ◽  
...  
Keyword(s):  
United States ◽  
Severe Acute Respiratory Syndrome ◽  
Disease Transmission ◽  
Emerging Infectious Diseases ◽  
Genomic Data ◽  
The United States ◽  
Cellular Damage ◽  
Animal Reservoir ◽  
Live Virus ◽  
The World

ABSTRACT Despite numerous barriers to transmission, zoonoses are the major cause of emerging infectious diseases in humans. Among these, severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and ebolaviruses have killed thousands; the human immunodeficiency virus (HIV) has killed millions. Zoonoses and human-to-animal cross-species transmission are driven by human actions and have important management, conservation, and public health implications. The current SARS-CoV-2 pandemic, which presumably originated from an animal reservoir, has killed more than half a million people around the world and cases continue to rise. In March 2020, New York City was a global epicenter for SARS-CoV-2 infections. During this time, four tigers and three lions at the Bronx Zoo, NY, developed mild, abnormal respiratory signs. We detected SARS-CoV-2 RNA in respiratory secretions and/or feces from all seven animals, live virus in three, and colocalized viral RNA with cellular damage in one. We produced nine whole SARS-CoV-2 genomes from the animals and keepers and identified different SARS-CoV-2 genotypes in the tigers and lions. Epidemiologic and genomic data indicated human-to-tiger transmission. These were the first confirmed cases of natural SARS-CoV-2 animal infections in the United States and the first in nondomestic species in the world. We highlight disease transmission at a nontraditional interface and provide information that contributes to understanding SARS-CoV-2 transmission across species. IMPORTANCE The human-animal-environment interface of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important aspect of the coronavirus disease 2019 (COVID-19) pandemic that requires robust One Health-based investigations. Despite this, few reports describe natural infections in animals or directly link them to human infections using genomic data. In the present study, we describe the first cases of natural SARS-CoV-2 infection in tigers and lions in the United States and provide epidemiological and genetic evidence for human-to-animal transmission of the virus. Our data show that tigers and lions were infected with different genotypes of SARS-CoV-2, indicating two independent transmission events to the animals. Importantly, infected animals shed infectious virus in respiratory secretions and feces. A better understanding of the susceptibility of animal species to SARS-CoV-2 may help to elucidate transmission mechanisms and identify potential reservoirs and sources of infection that are important in both animal and human health.

Knowledge and governance in the digital age: The politics of monitoring planetary life

First Monday ◽  
2006 ◽  
Author(s):  
Robert Latham
Keyword(s):  
Climate Change ◽  
United States ◽  
Global Climate Change ◽  
Disease Transmission ◽  
Global Climate ◽  
The United States ◽  
Monitoring Systems ◽  
Processing Technologies ◽  
Building Monitoring ◽  
The World

Planetary phenomena, such as global climate change and transborder disease transmission, are increasing subject to monitoring aided by advances in surveillance and data processing technologies. The most powerful governments of the world, especially the United States, are building monitoring systems they can control. Communities and activists around the world face a fundamental choice: become involved in shaping those systems so they better serve the needs and interests of the world’s population or build their own independent, unofficial monitoring systems.

scholarly journals COVID-19 Epidemic and Pattern of Global Distribution

2020 ◽  
Vol 5 (3) ◽  
pp. 125-137
Keyword(s):  
United States ◽  
Severe Acute Respiratory Syndrome ◽  
United States Of America ◽  
The United States ◽  
European Countries ◽  
Geographical Pattern ◽  
The World ◽  
Global Spread ◽  
The Uk ◽  
Viral Outbreak

The coronavirus disease (COVID-19) is a highly contagious viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which originated in Wuhan, China, and spread around the world. We have understudied the epidemiological and geographical pattern of distribution of COVID-19 in five different continents of global spread. An online sample of distribution was successfully recruited from America, Africa, Oceania, Asia, and Europe. The epidemiological curve and pattern of geographical distribution as of 9th and 10th April 2020 were also reviewed and results show that European countries like France, Spain, Italy, the UK and the United States of America indicate an epidemic progression relative to the same curve detected in China in January and February 2020. European countries record more cases since the outbreak of the resulted deadly COVID-19, followed by Asia and America. We call for a vital need for countries to develop effective vaccines and therapeutic combinations to cope with this viral outbreak globally.

scholarly journals Emerging SARS-CoV-2 Variants: A Review of Its Mutations, Its Implications and Vaccine Efficacy

Vaccines ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 1195
Author(s):  
Sindhu Ramesh ◽  
Manoj Govindarajulu ◽  
Rachel S. Parise ◽  
Logan Neel ◽  
Tharanath Shankar ◽  
...  
Keyword(s):  
United States ◽  
Severe Acute Respiratory Syndrome ◽  
Vaccine Efficacy ◽  
Severe Disease ◽  
The United States ◽  
Health Concern ◽  
Close Monitoring ◽  
The World ◽  
Control And Prevention ◽  
Significant Health

The widespread increase in multiple severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants is causing a significant health concern in the United States and worldwide. These variants exhibit increased transmissibility, cause more severe disease, exhibit evasive immune properties, impair neutralization by antibodies from vaccinated individuals or convalescence sera, and reinfection. The Centers for Disease Control and Prevention (CDC) has classified SARS-CoV-2 variants into variants of interest, variants of concern, and variants of high consequence. Currently, four variants of concern (B.1.1.7, B.1.351, P.1, and B.1.617.2) and several variants of interests (B.1.526, B.1.525, and P.2) are characterized and are essential for close monitoring. In this review, we discuss the different SARS-CoV-2 variants, emphasizing variants of concern circulating the world and highlight the various mutations and how these mutations affect the characteristics of the virus. In addition, we discuss the most common vaccines and the various studies concerning the efficacy of these vaccines against different variants of concern.

Sex Differences in Mass Media Preferences Across Four Asian Countries

2011 ◽  
Vol 23 (4) ◽  
pp. 186-191 ◽  
Author(s):  
Malini Ratnasingam ◽  
Lee Ellis
Keyword(s):  
United States ◽  
Sex Differences ◽  
Mass Media ◽  
The United States ◽  
Female Students ◽  
The Internet ◽  
Evolutionary Explanation ◽  
Asian Countries ◽  
The World ◽  
Media Preferences

Background. Nearly all of the research on sex differences in mass media utilization has been based on samples from the United States and a few other Western countries. Aim. The present study examines sex differences in mass media utilization in four Asian countries (Japan, Malaysia, South Korea, and Singapore). Methods. College students self-reported the frequency with which they accessed the following five mass media outlets: television dramas, televised news and documentaries, music, newspapers and magazines, and the Internet. Results. Two significant sex differences were found when participants from the four countries were considered as a whole: Women watched television dramas more than did men; and in Japan, female students listened to music more than did their male counterparts. Limitations. A wider array of mass media outlets could have been explored. Conclusions. Findings were largely consistent with results from studies conducted elsewhere in the world, particularly regarding sex differences in television drama viewing. A neurohormonal evolutionary explanation is offered for the basic findings.

Sandra Ramos Revisited

2020 ◽  
Vol 2 (4) ◽  
pp. 32-54
Author(s):  
Silvia Spitta
Keyword(s):  
United States ◽  
The United States ◽  
Ancient Greek ◽  
Graphic Arts ◽  
Left Behind ◽  
The World ◽  
The Usa ◽  
Political Choices ◽  
The Rich

Sandra Ramos (b. 1969) is one of the few artists to reflect critically on both sides of the Cuban di-lemma, fully embodying the etymological origins of the word in ancient Greek: di-, meaning twice, and lemma, denoting a form of argument involving a choice between equally unfavorable alternatives. Throughout her works she shines a light on the dilemmas faced by Cubans whether in Cuba or the United States, underlining the bad personal and political choices people face in both countries. During the hard 1990s, while still in Havana, the artist focused on the traumatic one-way journey into exile by thousands, as well as the experience of profound abandonment experienced by those who were left behind on the island. Today she lives in Miami and operates a studio there as well as one in Havana. Her initial disorientation in the USA has morphed into an acerbic representation and critique of the current administration and a deep concern with the environmental collapse we face. A buffoonlike Trumpito has joined el Bobo de Abela and Liborio in her gallery of comic characters derived from the rich Cuban graphic arts tradition where she was formed. While Cuba is now represented as a rotten cake with menacing flies hovering over it ready to pounce, a bombastic Trumpito marches across the world stage, trampling everything underfoot, a dollar sign for a face.

The Unquiet Frontier

2017 ◽  
Author(s):  
Jakub J. Grygiel ◽  
A. Wess Mitchell ◽  
Jakub J. Grygiel ◽  
A. Wess Mitchell
Keyword(s):  
United States ◽  
The United States ◽  
Great Powers ◽  
Global Order ◽  
American Power ◽  
Alliance Networks ◽  
Effective Strategies ◽  
The World ◽  
The Baltic ◽  
Critical Regions

From the Baltic to the South China Sea, newly assertive authoritarian states sense an opportunity to resurrect old empires or build new ones at America's expense. Hoping that U.S. decline is real, nations such as Russia, Iran, and China are testing Washington's resolve by targeting vulnerable allies at the frontiers of American power. This book explains why the United States needs a new grand strategy that uses strong frontier alliance networks to raise the costs of military aggression in the new century. The book describes the aggressive methods which rival nations are using to test American power in strategically critical regions throughout the world. It shows how rising and revisionist powers are putting pressure on our frontier allies—countries like Poland, Israel, and Taiwan—to gauge our leaders' commitment to upholding the American-led global order. To cope with these dangerous dynamics, nervous U.S. allies are diversifying their national-security “menu cards” by beefing up their militaries or even aligning with their aggressors. The book reveals how numerous would-be great powers use an arsenal of asymmetric techniques to probe and sift American strength across several regions simultaneously, and how rivals and allies alike are learning from America's management of increasingly interlinked global crises to hone effective strategies of their own. The book demonstrates why the United States must strengthen the international order that has provided greater benefits to the world than any in history.

Bringing the Real World of Science to Children: A Partnership of the American Museum of Natural History and the City University of New York

2008 ◽  
Vol 12 (1) ◽  
Author(s):  
Anthony G Picciano ◽  
Robert V. Steiner
Keyword(s):  
United States ◽  
New York ◽  
Natural History ◽  
Local Governments ◽  
Compulsory Education ◽  
Development Program ◽  
The United States ◽  
American Museum ◽  
The World ◽  
The City

Every child has a right to an education. In the United States, the issue is not necessarily about access to a school but access to a quality education. With strict compulsory education laws, more than 50 million students enrolled in primary and secondary schools, and billions of dollars spent annually on public and private education, American children surely have access to buildings and classrooms. However, because of a complex and competitive system of shared policymaking among national, state, and local governments, not all schools are created equal nor are equal education opportunities available for the poor, minorities, and underprivileged. One manifestation of this inequity is the lack of qualified teachers in many urban and rural schools to teach certain subjects such as science, mathematics, and technology. The purpose of this article is to describe a partnership model between two major institutions (The American Museum of Natural History and The City University of New York) and the program designed to improve the way teachers are trained and children are taught and introduced to the world of science. These two institutions have partnered on various projects over the years to expand educational opportunity especially in the teaching of science. One of the more successful projects is Seminars on Science (SoS), an online teacher education and professional development program, that connects teachers across the United States and around the world to cutting-edge research and provides them with powerful classroom resources. This article provides the institutional perspectives, the challenges and the strategies that fostered this partnership.

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