Polyvinyl alcohol/silica hybrid microspheres: synthesis, characterization and potential applications as adsorbents

2019 ◽  
Vol 6 (5) ◽  
pp. 055201
Author(s):  
Shu-Hua Teng ◽  
Niu Niu ◽  
Feng-Wu Chen ◽  
Peng Wang
Keyword(s):  
Polyvinyl Alcohol ◽  
Potential Applications ◽  
Silica Hybrid

scholarly journals Evaluation of Polyvinyl Alcohol/Cobalt Substituted Hydroxyapatite Nanocomposite as a Potential Wound Dressing for Diabetic Foot Ulcers

2020 ◽  
Vol 21 (22) ◽  
pp. 8831
Author(s):  
Wei-Chun Lin ◽  
Cheng-Ming Tang
Keyword(s):  
Polyvinyl Alcohol ◽  
Diabetic Foot ◽  
Wound Dressing ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
E Coli ◽  
Accelerate Wound Healing ◽  
Persistent Infections ◽  
Electrochemically Deposited ◽  
Potential Applications

Diabetic foot ulcers (DFUs) caused by diabetes are prone to serious and persistent infections. If not treated properly, it will cause tissue necrosis or septicemia due to peripheral blood vessel embolism. Therefore, it is an urgent challenge to accelerate wound healing and reduce the risk of bacterial infection in patients. In clinical practice, DFUs mostly use hydrogel dressing to cover the surface of the affected area as an auxiliary treatment. Polyvinyl alcohol (PVA) is a hydrophilic hydrogel polymer widely used in dressings, drug delivery, and medical applications. However, due to its weak bioactivity and antibacterial ability, leads to limited application. Filler adding is a useful way to enhance the biocompatibility of PVA. In our study, cobalt-substituted hydroxyapatite (CoHA) powder was prepared by the electrochemically-deposited method. PVA and PVA-CoHA nanocomposite were prepared by the solvent casting method. The bioactivity of the PVA and composite was evaluated by immersed in simulated body fluid for 7 days. In addition, L929 cells and E. coli were used to evaluate the cytotoxicity and antibacterial tests of PVA and PVA-CoHA nanocomposite. The results show that the addition of CoHA increases the mechanical properties and biological activity of PVA. Biocompatibility evaluation showed no significant cytotoxicity of PVA-CoHA composite. In addition, a small amount of cobalt ion was released to the culture medium from the nanocomposite in the cell culture period and enhanced cell growth. The addition of CoHA also confirmed that it could inhibit the growth of E. coli. PVA-CoHA composite may have potential applications in diabetic trauma healing and wound dressing.

Mechanical Behavior of Bioactive Glass-Polyvinyl Alcohol Hybrid Foams Obtained by the Sol-Gel Process

2005 ◽  
Vol 284-286 ◽  
pp. 757-760 ◽  
Author(s):  
Marivalda Pereira ◽  
Showan N. Nazhat ◽  
Julian R. Jones ◽  
Larry L. Hench
Keyword(s):  
Polyvinyl Alcohol ◽  
Bioactive Glass ◽  
Mechanical Behavior ◽  
Sol Gel ◽  
Precursor Solution ◽  
High Porosity ◽  
Soft Tissue Regeneration ◽  
Sol Gel Process ◽  
Potential Applications ◽  
Hybrid Foams

The possibility of enhancing mechanical properties by incorporation of polymeric components to sol-gel derived materials is extremely attractive to prepare macroporous scaffolds, leading to materials with potential applications in both hard and soft tissue regeneration. In this work bioactive glass-polyvinyl alcohol hybrids were developed and their mechanical behavior was evaluated. Hybrids were synthesized by adding polyvinyl alcohol to a sol-gel precursor solution, which was then foamed with the addition of a surfactant and vigorous agitation. The foams were cast, aged and dried at 40°C. A cleaning step to decrease the acidic character of the obtained hybrids was undertaken by immersion in a NH4OH solution. The mechanical behavior of the hybrids was evaluated in compression using both stress and strain control tests. Hybrid foams had a high porosity varying from 60-90% and the macropore diameter ranged from 10 to 600 µm. The modal macropore diameter varied with the inorganic phase composition and with the polymer content in the hybrid. The strain at fracture of the as prepared hybrid foams was substantially greater than pure gel-glass foams. The cleaned hybrids presented a slightly higher strength and lower deformation than the as prepared foams.

scholarly journals Electrospun polyvinyl alcohol-honey nanofibers

2013 ◽  
Vol 17 (5) ◽  
pp. 1549-1550 ◽  
Author(s):  
Ping Wang ◽  
Ji-Huan He
Keyword(s):  
Polyvinyl Alcohol ◽  
Environmentally Friendly ◽  
Potential Applications ◽  
Wide Potential

This paper sugeests a method for fabrication of polyvinyl alcohol-honey nanofibers by electrospinning. Polyvinyl alcohol and honey are all biocompatible and environmentally friendly materials. This combination will lead to wide potential applications in various engineering fields.

scholarly journals Functional Cross-Linked Electrospun Polyvinyl Alcohol Membranes and Their Potential Applications

2017 ◽  
Vol 302 (8) ◽  
pp. 1700024 ◽  
Author(s):  
Yen Bach Truong ◽  
Jonghyun Choi ◽  
James Mardel ◽  
Yuan Gao ◽  
Sabrina Maisch ◽  
...  
Keyword(s):  
Polyvinyl Alcohol ◽  
Potential Applications

scholarly journals Silica hybrid biomaterials containing gelatin synthesized by sol-gel method

2010 ◽  
Vol 8 (4) ◽  
pp. 870-876 ◽  
Author(s):  
Georgi Chernev ◽  
Borislava Borisova ◽  
Lyudmila Kabaivanova ◽  
Isabel Salvado
Keyword(s):  
Sol Gel ◽  
Bacterial Cells ◽  
Bet Analysis ◽  
Structure Surface ◽  
Potential Applications ◽  
Ft Ir ◽  
Degradation Activity ◽  
Sol Gel Synthesis ◽  
Hybrid Biomaterials ◽  
Silica Hybrid

AbstractThis work reports the sol-gel synthesis of silica hybrids. We determined the effect of the type and quantity of silica precursors and organic compounds on the resulting structure, surface area, nanostructure design and size, and potential applications. The structure of the synthesized hybrids was analyzed using FT-IR, XRD, BET-Analysis, SEM, and AFM. We demonstrate the immovilization of whole living thermophilic bacterial cells with cyanocompound degradation activity in the synthesized silica hybrid biomaterials by entrapment, chemical binding, and adsorption.

scholarly journals A freeze–thaw PVA hydrogel loaded with guava leaf extract: physical and antibacterial properties

RSC Advances ◽  
2021 ◽  
Vol 11 (48) ◽  
pp. 30156-30171
Author(s):  
William Xaveriano Waresindo ◽  
Halida Rahmi Luthfianti ◽  
Dhewa Edikresnha ◽  
Tri Suciati ◽  
Fatimah Arofiati Noor ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Polyvinyl Alcohol ◽  
Wound Dressing ◽  
Leaf Extract ◽  
Antibacterial Properties ◽  
Freeze Thaw ◽  
Good Antibacterial Activity ◽  
Potential Applications ◽  
Guava Leaf ◽  
Pva Hydrogel

A polyvinyl alcohol (PVA) hydrogel loaded with guava leaf extract (GLE) has potential applications as a wound dressing with good antibacterial activity.

Synthesis and Characterization of Photopolymerized Poly(acrylic)/Monodispersed Colloidal Silica Hybrid Thin Films

2008 ◽  
Vol 47-50 ◽  
pp. 662-665
Author(s):  
Wen Chen Chien ◽  
Yang Yen Yu ◽  
Shih Yu Chen
Keyword(s):  
Thin Films ◽  
Silica Particle ◽  
Colloidal Silica ◽  
Silica Content ◽  
Hybrid Films ◽  
Coverage Area ◽  
Acrylic Polymer ◽  
Potential Applications ◽  
Hybrid Thin Films ◽  
Silica Hybrid

In this study, poly(acrylic)/silica hybrid thin films were prepared from various acrylic monomers and monodispersed colloidal silica with a coupling agent MSMA. The silica content in the hybrid thin films was varied from 0 to 50 wt%. The experimental results showed that the coverage area of silica particle by the MSMA decreased with increasing silica content and resulted in the aggregation of silica particle in the hybrid films. Thus, the silica domain in the hybrid films was varied from 20 to 35 nm by the different mole ratios of MSMA to silica. The results of SEM, TEM, and EA supported the above results. The analysis of FTIR and Raman spectra indicated that the degree of photopolymerization was very high. The prepared hybrid films from the crosslinked acrylic polymer moiety showed much better film uniformity, thermal stability and mechanical properties than those obtained from poly(methyl methacrylate). The refractive index decreased linearly with increasing the silica fraction in the hybrid films. Excellent optical transparency was obtained in the prepared hybrid films. These results showed that the prepared hybrid thin films had potential applications as passive films for optical devices.

scholarly journals Novel PVA-Based Microspheres Co-Loaded with Photothermal Transforming Agent and Chemotherapeutic for Colorectal Cancer Treatment

Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 984
Author(s):  
Yao Zhang ◽  
Zirui He ◽  
Fan Yang ◽  
Changqing Ye ◽  
Xia Xu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Polyvinyl Alcohol ◽  
Laser Irradiation ◽  
Near Infrared ◽  
Photothermal Effect ◽  
Tumor Treatment ◽  
Mos2 Nanosheets ◽  
Potential Applications ◽  
Conversion Performance ◽  
Stability Results

Background: We previously designed an electrospinning chitosan (CS) nanofiber-based carrier, using polyvinyl alcohol (PVA) as an adjuvant to deliver doxorubicin (DOX) and MoS2 nanosheets for postoperative tumor re-occurrence inhibition. However, owing to that the nanofibrous mat is un-injectable, this composite nanofiber is far from being clinically applicable. Materials and Methods: Via modulating the electrospray parameters, polyvinyl alcohol (PVA) beads string doped with DOX and MoS2 (PVA/MoS2/DOX microspheres) were prepared, which were further crosslinked with glutaraldehyde to obtain the water-stability. Results: Under the 808-nm laser irradiation, MoS2 nanosheets rendered the prepared PVA/MoS2/DOX microspheres an excellent light-to-heat conversion performance with η of 23.2%. Besides, the heat generated by near-infrared laser irradiation can improve the effect of chemotherapy by promoting the release rate of DOX. HT29 cell and tumor-bearing nude mice were used to systematically study the combined tumor treatment efficiency of composite nanospheres. Conclusion: PVA/MoS2/DOX nanospheres have excellent photothermal effect and chemotherapy effect, which can completely suppress the tumor recurrence. Therefore, the PVA/MoS2/DOX nanospheres are anticipated to find potential applications in the treatment of local colorectal cancer.

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