The Relationship of Age with the Autism-Spectrum Quotient Scale in a Large Sample of Adults

2021 ◽  
Author(s):  
Jennifer Lodi-Smith ◽  
Jonathan D. Rodgers ◽  
Valeria Marquez Luna ◽  
Sarah Khan ◽  
Caleb J. Long ◽  
...  
Keyword(s):  
Autism Spectrum ◽  
Autism Spectrum Quotient ◽  
Large Sample ◽  
Relationship Of ◽  
The Relationship

How matrix metalloproteinase (MMP)-9 (rs3918242) polymorphism affects MMP-9 serum concentration and associates with autism spectrum disorders: A case-control study in Iranian population

2021 ◽  
pp. 1-7
Author(s):  
Javid Rezaei Lord ◽  
Farhad Mashayekhi ◽  
Zivar Salehi
Keyword(s):  
Serum Concentration ◽  
Matrix Metalloproteinase ◽  
Serum Levels ◽  
Autism Spectrum ◽  
Enzyme Linked Immunosorbent Assay ◽  
Mmp9 Expression ◽  
Relationship Of ◽  
The Relationship ◽  
Metalloproteinase 9 ◽  
Control Study

Abstract The aim of this project was to evaluate the relationship of matrix metalloproteinase-9 (MMP-9) genetic variation and its serum concentration with autism spectrum disorder (ASD). One hundred ASD and 120 controls were enrolled in this study. Genomic DNA was extracted from blood and MMP-9 polymorphism was determined by polymerase chain reaction restriction fragment length polymorphism and serum levels were measured by enzyme-linked immunosorbent assay. The frequencies of CC, CT, and TT genotypes were 72%, 26%, and 2% in controls and 31%, 57%, and 12% in ASD, respectively. The frequencies of C and T alleles in ASD were 59.5% and 40.5%, and controls were 86% and 14%, respectively. There is a significant increase in serum MMP-9 levels in ASD as compared to controls. We have also shown that TT genotype is significantly associated with increase serum MMP-9 levels in patients (TT, CT, and CC serum levels were 91.77 ± 10.53, 70.66 ± 7.21, and 38.66 ± 5.52 and in controls were 55.55 ± 11.39, 42.66 ± 7.85, and 30.55 ± 6.34 ng/ml, respectively). It is concluded that there is a significant association between rs3918242 MMP-9 polymorphism and its serum concentration with autism. We also suggest that TT genotype is associated with increased MMP9 expression and may be a risk factor for ASD.

scholarly journals HUBUNGAN PENGGUNAAN DIAPERS DENGAN KEMAMPUAN TOILETING PADA ANAK

2018 ◽  
Vol 2 (1) ◽  
pp. 117
Author(s):  
Rendika Baharudin Abror ◽  
Cholik Harun Rosjidi ◽  
Rika Maya Sari
Keyword(s):  
Data Collection ◽  
Toilet Training ◽  
P Value ◽  
Developmental Tasks ◽  
Chi Square ◽  
Cross Sectional ◽  
Large Sample ◽  
Relationship Of ◽  
The Relationship

AbstractEach child has a task that must be passed well, especially at the age of the child (12-36 months). One of the developmental tasks in toddlers is toilet training. Long-term use of diapers can cause toilet effects. This study aims to determine the relationship between diapers with the ability of toileting in children.The design of this research is Correlation with cross sectional approach. Large sample of 70 respondents. Sampling of the study using total sampling, data collection using questionnaires and calculations using Chi-square Correlation test using SPSS 16.0 error α 0.05.The results of the research variables The use of diapers in children interpreted most of the 47 children of respondents (67.1%) Did not use and almost half of the 23 respondents (32.9%) use. The ability of toileting in children is interpreted by most of the 42 respondents (60.0%) fulfilled, and almost half of 28 respondents (40.0%) are not met.Based on the calculation of Chi-square SPSS statistic shows that p value 0,000 <0,05) means that there is relationship of diaper usage with the ability of toileting in children with the closeness of cc relationship of 0.479 enough category.The results of this study concluded that almost half of them use diapers, and almost half of them do not meet the ability of toileting, the researcher suggests in the research place to put a picture or leaflet about the effect of Diaper Usage on Toileting Ability so that the wise mother in using Diapers.Keywords: diapers, toileting, children AbstrakSetiap anak mempunyai tugas perkembangan yang harus dilewati dengan baik, terlebih pada usia toddler (12-36 bulan). Salah satu tugas perkembangan pada anak usia toddler adalah toilet training. Pemakaian diapers dalam jangka panjang dapat menimbulkan efek yang berbahaya serta bisa menghambat kemampuan toilet training anak. Penelitian ini bertujuan untuk mengetahui Hubungan Penggunaan diapers dengan kemampuan toileting pada anakDesain penelitian ini adalah Korelasi dengan pendekatan cross sectional. Besar sampel 70 responden. Sampling penelitian menggunakan Total sampling, pengumpulan data menggunakan kuesioner dan perhitungan menggunakan uji Korelasi Chi-square dengan menggunakan SPSS 16.0 kesalahan α 0,05.Hasil penelitian variabel Penggunaan diapers pada anak diinterpretasikan sebagian besar 47 anak responden (67,1%) Tidak menggunakan dan hampir setengahnya 23 responden (32,9%) menggunakan. Pada kemampuan toileting pada anak diinterpretasikan sebagian besar 42 responden (60,0%) tercapai, dan hampir setengahnya 28 responden (40,0%) belum tercapai.Berdasarkan perhitungan uji statistik Chi-square SPSS menunjukkan p value 0,000< 0,05) artinya ada hubungan penggunaan diapers dengan kemampuan toileting pada anak dengan keeratan hubungan cc sebesar 0,479 kategori cukupHasil penelitian disimpulkan hampir setengahnya menggunakan diapers, dan hampir setengahnya belum tercapai kemampuan toileting maka peneliti menyarankan pada tempat penelitian untuk memasang gambar atau leaflet tentang dampak Penggunaan Diapers Terhadap Kemampuan Toileting, sehingga ibu bijak dalam menggunakan Diapers.Kata kunci: Diapers, Toileting, Anak.

scholarly journals Patterns of Contagious Yawning and Itching Differ Amongst Adults With Autistic Traits vs. Psychopathic Traits

2021 ◽  
Vol 12 ◽  
Author(s):  
Molly S. Helt ◽  
Taylor M. Sorensen ◽  
Rachel J. Scheub ◽  
Mira B. Nakhle ◽  
Anna C. Luddy
Keyword(s):  
Eye Gaze ◽  
Autistic Traits ◽  
Autism Spectrum ◽  
Psychopathic Traits ◽  
Reactivity Index ◽  
Autism Spectrum Quotient ◽  
Contagious Yawning ◽  
Different Types ◽  
The Relationship ◽  
Underlying Processes

Both individuals with diagnosed with Autism Spectrum Disorder (ASD) and individuals high in psychopathic traits show reduced susceptibility to contagious yawning; that is, yawning after seeing or hearing another person yawn. Yet it is unclear whether the same underlying processes (e.g., reduced eye gaze) are responsible for the relationship between reduced contagion and these very different types of clinical traits. College Students (n = 97) watched videos of individuals yawning or scratching (a form of contagion not reliant on eye gaze for transmission) while their eye movements were tracked. They completed the Interpersonal Reactivity Index (IRI), the Autism-Spectrum Quotient (AQ), the Psychopathy Personality Inventory-Revised (PPI-R), and the Adolescent and Adult Sensory Processing Disorder Checklist. Both psychopathic traits and autistic traits showed an inverse relationship to contagious yawning, consistent with previous research. However, the relationship between autistic (but not psychopathic) traits and contagious yawning was moderated by eye gaze. Furthermore, participants high in autistic traits showed typical levels of contagious itching whereas adults high in psychopathic traits showed diminished itch contagion. Finally, only psychopathic traits were associated with lower overall levels of empathy. The findings imply that the underlying processes contributing to the disruptions in contagious yawning amongst individuals high in autistic vs. psychopathic traits are distinct. In contrast to adults high in psychopathic traits, diminished contagion may appear amongst people with high levels of autistic traits secondary to diminished attention to the faces of others, and in the absence of a background deficit in emotional empathy.

scholarly journals Therianthropy: Wellbeing, Schizotypy, and Autism in Individuals Who Self-Identify as Non-Human

2019 ◽  
Vol 27 (4) ◽  
pp. 403-426
Author(s):  
Helen Clegg ◽  
Roz Collings ◽  
Elizabeth C. Roxburgh
Keyword(s):  
Social Relationships ◽  
Social Factors ◽  
Protective Factor ◽  
Autism Spectrum ◽  
Cognitive Factors ◽  
Psychological Wellbeing ◽  
Autism Spectrum Quotient ◽  
Health And Wellbeing ◽  
Human Animal ◽  
The Relationship

AbstractTherianthropy is the belief that one is at least part non-human animal. This study aimed to address the dichotomization surrounding therianthropy in relation to mental health and wellbeing. One hundred and twelve therians and 265 non-therians completed Ryff’s Scales of Psychological Wellbeing, the O-LIFE questionnaire, and the Autism Spectrum Quotient. The results showed that therians scored lower on variables that are associated with positive social relationships. Such findings may be explained by cognitive factors and/or social factors that are associated with the stigmatization of cross-species identities. However, being a therian moderated the relationship between both autism and introverted anhedonia in relation to autonomy. Thus, a therian identity may act as a protective factor for those experiencing higher levels of autism and schizotypy.

scholarly journals The relationship of Rett syndrome and MECP2 disorders to autism

2012 ◽  
Vol 14 (3) ◽  
pp. 253-262 ◽  
Keyword(s):  
Rett Syndrome ◽  
Neurodevelopmental Disorder ◽  
Autism Spectrum ◽  
Protein Product ◽  
The Many ◽  
Clinical Conditions ◽  
Relationship Of ◽  
The Relationship ◽  
Clinical Problems ◽  
Insight Into

Rett syndrome (RTT, MIM#312750) is a neurodevelopmental disorder that is classified as an autism spectrum disorder. Clinically, RTT is characterized by psychomotor regression with loss of volitional hand use and spoken language, the development of repetitive hand stereotypies, and gait impairment. The majority of people with RTT have mutations in Methyl-CpG-binding Protein 2 (MECP2), a transcriptional regulator. Interestingly, alterations in the function of the protein product produced by MECP2, MeCP2, have been identified in a number of other clinical conditions. The many clinical features found in RTT and the various clinical problems that result from alteration in MeCP2 function have led to the belief that understanding RTT will provide insight into a number of other neurological disorders. Excitingly, RTT is reversible in a mouse model, providing inspiration and hope that such a goal may be achieved for RTT and potentially for many neurodevelopmental disorders.

The Relationship of Symptom Severity and Pretend Play in Children With Autism Spectrum Disorder (ASD)

2020 ◽  
Vol 74 (4_Supplement_1) ◽  
pp. 7411500049p1
Author(s):  
Yu-Ling Chen ◽  
I-Ning Fu ◽  
Meng-Ru Liu ◽  
Yen-Ting Yu ◽  
Hsing-Jung Li ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Symptom Severity ◽  
Pretend Play ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Relationship Of ◽  
The Relationship

Relationship Between Autism Spectrum Disorder Characteristics and Humor Appreciation in Typically Developing Individuals

2018 ◽  
Vol 122 (6) ◽  
pp. 2282-2297
Author(s):  
Kai Nagase
Keyword(s):  
Autism Spectrum Disorder ◽  
Autistic Traits ◽  
Japanese Version ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Autism Spectrum Quotient ◽  
Typically Developing ◽  
Attention Switching ◽  
Humor Appreciation ◽  
The Relationship

Extant research regarding humor appreciation in individuals with autism spectrum disorder has been equivocal. This study aims to clarify the relationship between the severity of autism spectrum disorder characteristics and humor appreciation in typically developing individuals. We hypothesized that the severity of autistic traits would have a U-shaped linear relationship with humor appreciation. Eighty typically developing undergraduates between the ages of 18 and 22 years ( Mage = 20.20; SDage = 1.08) were recruited for this study. They were asked to answer 24 statements, devised to measure humor appreciation, in response to a joke stimulus comprising 12 typically funny daily life occurrences (two statements per episode). The participants also responded to the Japanese version of the Autism-Spectrum Quotient. A significant U-shaped relationship was observed between the severity of autistic traits and appreciation of humor. A similar significant U-shaped relationship was seen between humor appreciation and the Autism-Spectrum Quotient subscales of attention switching, communication, and imagination. Humor appreciation showed no significant U-shaped relationship with the Autism-Spectrum Quotient subscales of social skills and local details. This study identified ways that autistic traits may influence how people appreciate humor. These findings are discussed in relation to cognitive processes underlying humor appreciation.

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