scholarly journals Use of a Medical Records Linkage System to Enumerate a Dynamic Population Over Time: The Rochester Epidemiology Project

2011 ◽  
Vol 173 (9) ◽  
pp. 1059-1068 ◽  
Author(s):  
Jennifer L. St. Sauver ◽  
Brandon R. Grossardt ◽  
Barbara P. Yawn ◽  
L. Joseph Melton ◽  
Walter A. Rocca
BMJ Open ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. e032551 ◽  
Author(s):  
Graham Powell ◽  
John Logan ◽  
Victor Kiri ◽  
Simon Borghs

ObjectiveTo assess the evolution of antiepileptic drug (AED) treatment patterns and seizure outcomes in England from 2003 to 2016.Design, setting and participantsRetrospective cohort study of electronic medical records from Clinical Practice Research Datalink and National Health Service Digital Hospital Episode Statistics databases. Patients newly diagnosed with epilepsy were identified and followed until end of data availability. Three eras were defined starting 1 April 2003 (first National Institute for Health and Care Excellence (NICE) guideline); 1 September 2007 (Standard and New Antiepileptic Drugs publication); and 1 January 2012 (second NICE guideline).Outcome measuresTime from diagnosis to first AED; AED sequence; time from first AED to first 1-year remission period (no new AED attempts and no seizure-related healthcare events); time from first AED to refractoriness (third AED attempt regardless of reason); Kaplan-Meier analysis of time-to-event variables.Results4388 patients were included (mean follow-up: 6.8, 4.2 and 1.7 years by era). 84.6% of adults (≥16 years), 75.5% of children (<16) and 89.1% of elderly subgroup (65+) received treatment within 1 year; rates were generally stable over time. Treatment trends included reduced use of carbamazepine (adult first line, era 1: 34.9%; era 3: 10.7%) and phenytoin, earlier line and increased use of levetiracetam (adult first line, era 1: 2.6%; era 3: 26.2%) and lamotrigine (particularly in adults and elderly subgroup), and a larger number of different AEDs used. Valproate use shifted somewhat to later lines. Rates of 1-year remission within 2 years of starting treatment increased in adults (era 1: 71.9%; era 3: 81.4%) and elderly (era 1: 76.1%; era 3: 81.7%). Overall, 55.5% of patients relapsed after achieving 1-year remission. Refractoriness rates remained stable over time (~26% of adults within 5 years).ConclusionTreatment trends often were not aligned with era-relevant guidance. However, our results suggest a slight improvement in epilepsy treatment outcomes over the 13-year period.


2012 ◽  
Vol 87 (12) ◽  
pp. 1202-1213 ◽  
Author(s):  
Walter A. Rocca ◽  
Barbara P. Yawn ◽  
Jennifer L. St. Sauver ◽  
Brandon R. Grossardt ◽  
L. Joseph Melton

2020 ◽  
Author(s):  
Ana Carolina Cintra Nunes Mafra ◽  
João Luiz Miraglia ◽  
Fernando Antonio Basile Colugnati ◽  
Gilberto Soares Lourenço Padilha ◽  
Renata Rafaella Santos Tadeucci ◽  
...  

AbstractBackgroundThe quality of the patient’s medical records is strictly related to patient safety. Besides, its data are widely used in observational studies. However, the reliability of the information extracted from them is a matter of concern in audit processes to ensure inter-rater agreement (IRA). Thus, the objective of this study is to evaluate the IRA among members of the Patient’s Health Record Review Board (PHRRB), in routine auditing of medical records, and the impact of periodic discussions of results with raters.MethodsProspective longitudinal study conducted between July of 2015 and April of 2016 at Hospital Municipal Dr. Moysés Deutsch, a large public hospital in São Paulo. The PHRRB was composed of 12 physicians, 9 nurses and 3 physiotherapists, who audited medical records, monthly, with the number of raters changing throughout the study. It was carried out PHRRB meetings to reach a consensus on criteria that the members have to rate in the auditing process. It was created a review chart that raters should verify the registry of patient’s secondary diagnosis, chief complaint, history of presenting complaint, past medical history, medication history, physical exam and diagnostic testing. It was obtained the IRA every three months. The Gwet’s AC1 coefficient and Proportion of Agreement (PA) were calculated to evaluate the IRA for each item over time.ResultsThe study included 1884 items from 239 records with an overall full agreement among raters of 71.2%. A significant IRA increase by 16.5% (OR=1.17; 95% CI=1.03—1.32; p=0.014) was found in the routine PHRRB auditing, with no significant differences between the PA and the Gwet’s AC1, that showed a similar evolution over time. The PA decreased by 27.1% when at least one of the raters was absent from the review meeting (OR=0.73; 95% CI=0.53—1.00; p=0.048).ConclusionsMedical record quality has been associated with the quality of care and could be optimized and improved by targeted interventions. The PA and the Gwet’s AC1 are suitable agreement coefficients that are feasible to be incorporated in the routine of PHRRB evaluation process.


2012 ◽  
Vol 52 (5) ◽  
pp. 284
Author(s):  
Dewi Anggraini Wisnumurti

Background Congenital malformations are a global and continualissue, contributing to neonatal mortality. The incidence andprevalence, as well as distribution of congenital malformationsvary among countries.Objective To determine the 'prevalence, distribution, and trendsin congenital malformations which are important to develop plansto cope Mth the problem.Methods We reviewed all cases of congenital malformationsadmitted to the Neonatal Unit, Department of Child Health,Arifin Ahmad Hospital from 2008 to 2010. Data were collectedfrom medical records. Diagnoses of congenital malformationswere established by history-taking, physical examination,and specific laboratory tests. Trends in the distribution ofcongenital malformation types, as well as clinical outcomes werehighlighted.Results During the study period there were 2,317 infants admit-ted to the Neonatal Unit, 724 in 2008, 772 in 2009, and 821 in2010. Most patients were referred by other hospitals, at the ageof 0-3 days. Most patients had normal birth weight and were de-livered vaginally. Of the 2,317 infants, 302 were diagnosed withcongenital malformations; the most common congenital malfor-mations were of the digestive tract. The distribution of anomalytypes was relatively constant over time, but the proportion ofpatients Mth congenital malformations discharged alive increasedin the latter two years of the 3-year period studied.Conclusion Most infants in our study had congenital malforma-tions involving the gastrointestinal tract. Distribution trendswere constant over time. Further efforts should be made to bettermanage future cases. [Paediatr lndones. 2012;52:284,8].


2020 ◽  
Author(s):  
Jackson Steinkamp ◽  
Abhinav Sharma ◽  
Wasif Bala ◽  
Jacob J Kantrowitz

BACKGROUND Clinicians spend large amounts of their workday using electronic medical records (EMRs). Poorly designed documentation systems contribute to the proliferation of out-of-date information, increased time spent on medical records, clinician burnout, and medical errors. Beyond software interfaces, examining the underlying paradigms and organizational structures for clinical information may provide insights into ways to improve documentation systems. In particular, our attachment to the <i>note</i> as the major organizational unit for storing unstructured medical data may be a cause of many of the problems with modern clinical documentation. Notes, as currently understood, systematically incentivize information duplication and information scattering, both within a single clinician’s notes over time and across multiple clinicians’ notes. Therefore, it is worthwhile to explore alternative paradigms for unstructured data organization. OBJECTIVE The aim of this study is to demonstrate the feasibility of building an EMR that does not use notes as the core organizational unit for unstructured data and which is designed specifically to disincentivize information duplication and information scattering. METHODS We used specific design principles to minimize the incentive for users to duplicate and scatter information. By default, the majority of a patient’s medical history remains the same over time, so users should not have to redocument that information. Clinicians on different teams or services mostly share the same medical information, so all data should be collaboratively shared across teams and services (while still allowing for disagreement and nuance). In all cases where a clinician must state that information has remained the same, they should be able to <i>attest</i> to the information without redocumenting it. We designed and built a web-based EMR based on these design principles. RESULTS We built a medical documentation system that does not use notes and instead treats the chart as a single, dynamically updating, and fully collaborative workspace. All information is organized by clinical topic or problem. Version history functionality is used to enable granular tracking of changes over time. Our system is highly customizable to individual workflows and enables each individual user to decide which data should be structured and which should be unstructured, enabling individuals to leverage the advantages of structured templating and clinical decision support as desired without requiring programming knowledge. The system is designed to facilitate real-time, fully collaborative documentation and communication among multiple clinicians. CONCLUSIONS We demonstrated the feasibility of building a non–note-based, fully collaborative EMR system. Our attachment to the <i>note</i> as the only possible atomic unit of unstructured medical data should be reevaluated, and alternative models should be considered.


2019 ◽  
Vol 81 (03) ◽  
pp. 244-250
Author(s):  
Randall G. Krug ◽  
Elizabeth A. Bradley ◽  
Jamie J. Van Gompel

Background There is no consensus exists regarding which reconstructive approach, if any, should be used after performing transcranial lateral orbital wall resections. Rigid reconstruction is often done to prevent enophthalmos; however, it is not clear if this is a risk with extensive orbital wall resections for transcranial surgery. Objective To assess globe position dynamics in patients that underwent transcranial lateral and superior orbital wall resections without rigid reconstruction to determine if enophthalmos is a significant risk. Methods Preoperative (PO) and postoperative data were retrospectively collected from the electronic medical records of 55 adult patients undergoing lateral and superior orbital wall resections as part of a skull base approach. The globe positions were assessed radiologically at all available time points and used to track relative globe displacements over time. Results An evaluation of PO variables identified a relationship between maximum lesion diameters and globe positions dynamics. The composition of globe position presentations in the population remained relatively stable over time, with only 1 out of 55 patients (1.81%) developing postoperative enophthalmos. An assessment of mean globe displacements revealed improvements in the patients presenting with PO exophthalmos, and stability in the patients presenting with normal PO globe positions. Conclusions Excellent results in long-term postoperative globe position dynamics can be achieved without the use of rigid reconstruction after transcranial lateral and superior orbital wall resections, regardless of the PO globe positioning.


2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Mauro H. Schenone ◽  
Dorothy Miller ◽  
Jacques E. Samson ◽  
Giancarlo Mari

Objective. To describe the trends in incidence, characteristics, and outcomes of women with eclampsia.Methods. We reviewed and abstracted data from medical records of all women diagnosed with eclampsia in our institution from August 1998 to April 2011. In addition to overall characteristics and outcomes, the cases were stratified by onset: antenatal versus postnatal and early (<32 weeks of gestation) versus late antenatal cases (≥32 weeks of gestation). Comparisons were made using chi-square, Fisher's exact, Mann-WhitneyU, andt-tests. A two-sidedP<0.05was considered statistically significant.Results. We identified 87 eclampsia cases out of 59,388 deliveries; 62 cases were diagnosed before delivery, and 25 had a postnatal onset. Among the 62 antenatal cases, 41 were diagnosed before 32 weeks and 21 at or after 32 weeks of gestation. Antenatal cases had higher systolic (P=0.03) and diastolic (P=0.01) blood pressures, more abnormal dipstick-test proteinuria (P=0.002), and lower platelet counts (P≤0.001) than postnatal cases. Early eclampsia cases were complicated more often with HELLP syndrome than late eclampsia cases (P=0.007).Conclusion. The occurrence of eclampsia has decreased over time. The earlier the onset is, the worse the outcome appears to be.


2011 ◽  
Vol 26 (S2) ◽  
pp. 1017-1017
Author(s):  
J.M. Garcia Tellez ◽  
L. Gonzalez Saavedra ◽  
J.M. Sanchez-Moyano Lea

OjectiveBorderline Personality disorder is a well recognised syndrome. These patients show a clear emotional unstability, lack of control impulse, unpredictible auto and heteroaggresive behaviour, poor interpersonal realitionships and self image as well as brief psychotic episodes.The unspecific symtomatology and diagnostic difficulty derived from different nosographic frames makes their diagnosis and treatment a challenge. Through the analysis of their medical records we aim to know the age they sought specialized help, the symptomatology at first consultation, the treatment given and the outcome after years of therapy.MethodologySystematic review of all BPD patient's medical records treated in our Unit with a particular reference to age and symptoms at the start of treatment and at present. Medical records from the Childhood and Adolescence Psychiatric Unit were also reviewed to determine the most prominent symptoms at that time.ResultsWe found that the vast majority of cases contacted the psychiatric services in their adolescence and early adulthood, probably in relation to demands of daily life at that age. The most relevant symptoms at onset of illness were depressive mood and anxiety. As time went on depressive symptoms were the main complaint. The clinical state remained fairly stable over time.ConclusionsThere is a clear early onset of symptoms, in particular, affective ones (depression and anxiety) being prominent in childhood and preadolescence. Also there is a stable psychopathology over time which keep the patients on long term follow ups. This medical demand seemed to diminish at their fifth decade.


2018 ◽  
Vol 47 (2) ◽  
pp. 368-368j ◽  
Author(s):  
Walter A Rocca ◽  
Brandon R Grossardt ◽  
Scott M Brue ◽  
Cynthia M Bock-Goodner ◽  
Alanna M Chamberlain ◽  
...  

1995 ◽  
Vol 25 (5) ◽  
pp. 1065-1071 ◽  
Author(s):  
T. J. Soundy ◽  
A. R. Lucas ◽  
V. J. Suman ◽  
L. J. Melton

SYNOPSISNumerous studies have estimated the frequency of bulimia nervosa among high school girls and college women, but population-based trends in incidence in a community have not been reported.In this study we determined the incidence of bulimia nervosa by identifying persons residing in the community of Rochester, Minnesota, who had the disorder initially diagnosed during the 11-year period from 1980 to 1990. Using our comprehensive population-based data resource (the Rochester Epidemiology Project), we identified cases by screening 777 medical records with diagnoses of bulimia; feeding disturbance; rumination syndrome; adverse effects of cathartics, emetics, or diuretics; polyphagia; sialosis; or vomiting.We identified 103 Rochester residents (100 female and 3 male) who fulfilled DSM-III-R diagnostic criteria for bulimia nervosa during the 11-year study period. Mean ± S.D. age for females at the time of diagnosis was 23·0 ± 6·1 years (range, 14·4 to 40·2 years). Yearly incidence in females rose sharply from 7·4 per 100000 population in 1980 to 49·7 in 1983, and then remained relatively constant around 30 per 100000 population. The annual age-adjusted incidence rates were 26·5 per 100000 population for females and 0·8 per 100000 population for males. The overall age-and sex-adjusted annual incidence was 13·5 per 100000 population.Bulimia nervosa is a common disorder in adolescent girls and young women from 15 to 24 years of age. Histories of alcohol or drug abuse, depression, or anorexia nervosa were higher than expected in the general population.


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