The relationship between micronuclei in human lymphocytes and plasma levels of vitamin C, Vitamin E, Vitamin B12 and folic acid

Prophylaxis of severe forms of COVID-19 infection can be achieved by exercising, especially endurance, which stimulates mitochondrial biogenesis and improves their functionality, these organelles having a key role in the pathogenesis of the disease. Some drugs and supplements that stimulate mitochondrial biogenesis through exercise (6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox), ω3 fatty acids, vitamin C, zinc, vitamin B12, folic acid, magnesium, MitoQ) and others that inhibit it (acetylsalicylic acid, ibuprofen, acetaminophen).

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VITAMIN B12 AND FOLIC ACID VALUES IN PREMATURE INFANTS

PEDIATRICS ◽

10.1542/peds.50.4.584 ◽

1972 ◽

Vol 50 (4) ◽

pp. 584-589

Author(s):

Ambadas Pathak ◽

Herman A. Godwin ◽

Luis M. Prudent

Keyword(s):

Folic Acid ◽

Vitamin B12 ◽

Premature Infants ◽

Serum Vitamin ◽

Serum Folate ◽

Born Infant ◽

Low Concentrations ◽

Folate And Vitamin B12 ◽

Relationship Of ◽

The Relationship

The relationship of serum vitamin B12 and folic acid was studied in 24 premature infants. In 14 of the 24, low serum vitamin B12 values were found around 40 days of age. Serum folic acid concentrations were less frequently depressed and were usually associated with normal red cell folate values. No correlation between hematocrits and vitamin B12 or folate levels was found. It is suggested that low concentrations of serum folate and vitamin B12 result from low dietary intake coupled with increased demand by the prematurely born infant.

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Relationship of Nutritional Substance toward HB Content of Chronic Kidney Failure Patients which Running Hemodialysis

International Journal of Engineering and Advanced Technology - Regular Issue ◽

10.35940/ijeat.a1248.109119 ◽

2019 ◽

Vol 9 (1) ◽

pp. 1145-1450

Keyword(s):

Renal Failure ◽

Folic Acid ◽

Chronic Renal Failure ◽

Vitamin C ◽

Chronic Kidney Failure ◽

Cross Sectional Study ◽

Research Subjects ◽

Chi Square ◽

Cross Sectional ◽

The Relationship

Chronic Renal Failure (CRF) is a disease caused due to kidney damage or deterioration glomerulus filtrate rate (GFR/GFR/Glomerular Filtration Rate) <60 ml/min /1.73 m2 for ≥ 3 months. One of the complications that often appears in CRF is anemia or decrease of hemoglobin level in the blood that is related to the relationship intake of nutrients (protein, vitamin C, folic acid and iron). The purpose of this study was to determine the relationship Intake of nutrients (protein, vitamin C, folic acid and iron) on Hb levels of chronic renal failure patients undergoing hemodialysis in RSI Siti Khadijah Palembang. This type of research is an observational analytic with a cross-sectional study design. Population in this study were all outpatients with chronic renal failure undergoing hemodialysis in RSI Siti Khadijah Palembang with total research subjects were 50 subjects, taken using purposive sampling and analyzed using chi-square test. The result showed that there are 52% of patients with chronic renal failure are male more than female. The aged 50-64 years old is 44% and 30-49 years old are 32%. The percentage of outpatients who had an adequate intake of protein, vitamin C, folic acid and iron were 28%, 10%, 0%, and 18% respectively, meanwhile, most of the patients had low hemoglobin levels which were 94%. There was not a significant association between intake of nutrients (protein, vitamin C, folic acid and iron) on Hb levels of chronic renal failure patients undergoing hemodialysis in RSI Siti Khadijah Palembang. Based on these results, should be noted again nutrient intake (protein, vitamin C, folic acid and iron) outpatient before and after undergoing hemodialysis to support the optimal outcome of hemodialysis therapy.

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The effects of vitamin C, vitamin B6, vitamin B12, folic acid, riboflavin, and thiamin on the breast milk and maternal status of well-nourished women at 6 months postpartum

American Journal of Clinical Nutrition ◽

10.1093/ajcn/33.10.2151 ◽

1980 ◽

Vol 33 (10) ◽

pp. 2151-2156 ◽

Cited By ~ 47

Author(s):

M R Thomas ◽

S M Sneed ◽

C Wei ◽

P A Nail ◽

M Wilson ◽

...

Keyword(s):

Folic Acid ◽

Breast Milk ◽

Vitamin C ◽

Vitamin B12 ◽

Vitamin B6 ◽

Maternal Status

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Vegetarian Diet: A Boon or Bane for Health?

Journal of Medical Research and Innovation ◽

10.15419/jmri.84 ◽

2017 ◽

Vol 2 (1) ◽

pp. e000084

Author(s):

Varshil Mehta

Keyword(s):

Folic Acid ◽

Cardiovascular Diseases ◽

Vitamin C ◽

Vitamin B12 ◽

Dietary Fiber ◽

Kidney Stones ◽

Vegetarian Diet ◽

Animal Origin ◽

Saturated Fats ◽

Vegetarian Diets

In recent times, there have been many scientific evidences which suggest that wholesome vegetarian diets offer significant advantages compared to diets containing meat and other foods of animal origin. The benefits ranges from lower intakes of cholesterol, saturated fats, animal proteins and higher intakes of dietary fiber, vitamin C and E, carotenoids, magnesium, folic acid, and other phytochemicals. However, it is often said that vegetarian diet lacks the nutrients like vitamin B12, proteins, zinc, calcium etc., but if an “Appropriate diet with proper planning” involving supplements is consumed, these deficiencies will never exist. Through the present editorial, I would like to show few benefits of having a vegetarian meal. Keywords: Vegetarian diet, Benefits, Cardiovascular diseases, Cataracts, Kidney stones, Hyperlipidemia, Obesity.

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Hyperhomocysteinaemia, low folate concentrations and MTHFR C677T mutation in abdominal aortic aneurysm

VASA ◽

10.1024/0301-1526/a000347 ◽

2014 ◽

Vol 43 (3) ◽

pp. 181-188 ◽

Cited By ~ 7

Author(s):

Hui Cao ◽

Xinhua Hu ◽

Qiang Zhang ◽

Jun Li ◽

Bing Liu ◽

...

Keyword(s):

Abdominal Aortic Aneurysm ◽

Folic Acid ◽

Aortic Aneurysm ◽

Vitamin B12 ◽

Gene Mutation ◽

Plasma Levels ◽

Mthfr C677t ◽

Mthfr Gene ◽

Abdominal Aortic ◽

C677t Mutation

Background: Homocysteine (Hcy) has been implicated in abdominal aortic aneurysm (AAA). However, the association of Hcy, vitamin B12, and folate in patients with AAA has not been studied in China. This study was conducted with the aim to evaluate the relationship of vitamin B12, folic acid, and Hcy levels in AAA. Patients and methods: 463 patients who had AAA were included in this study. 463 control subjects were age- and sex-matched with the patients. In all of the subjects, we evaluated total plasma levels Hcy, vitamin B12, folic acid and the distribution of the C677T methylenetetrahydrofolate reductase (MTHFR) gene mutation. Results: The mean plasma Hcy levels were significantly higher in patients with AAA compared with controls (18.37 ± 6.97 vs. 12.89 ± 4.08 μmol/L, P < 0.001). The frequency of homozygous (TT) genotype in MTHFR C677T mutation was significantly higher in patients with AAA than that in control subjects (19.4 % vs. 11.9 %, P = 0.002). The fasting Hcy correlated negatively with folate (A r = - 0.311, P < 0.01; Control: r = - 0.348, P < 0.01). The aneurysm size was significantly greater (P < 0.001) in patients with hyperhomocysteinemia than that in patients with normal Hcy plasma levels. The size of the AAA had a linear correlation with the plasma Hcy level (r = 0.286; P< 0.001). Conclusions: Serum folate deficiency and hyperhomocysteinemia were associated with an increased risk of AAA in Northeast China. The homozygous (TT) genotype of MTHFR gene mutation may be a crucial hereditary risk factor in AAA.

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