scholarly journals P758 Should ECHO measurements be indexed to ideal BSA or actual BSA?

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
M Cases ◽  
T Zhu ◽  
U Jurt ◽  
D Brouillard ◽  
M Matangi

Abstract INTRODUCTION A patient with aortic stenosis with an AVA of 1.22 cm2 who stands 5’ 6" and weighs 145 lb has a BSA of 1.76m2 (AV area index = 0.69 cm2/m2). If the same patient weighs 200 lbs, the BSA increases to 2.09 m2 (AV area index 0.58 cm2/m2). Their calculated AV area index therefore changes from the moderate range to the severe range. PURPOSE To determine from our ECHO database the effect the current obesity epidemic has on all ECHO variables that are indexed to BSA. METHODS Our ECHO database was searched for all patients with the required data variables, gender, age, height (cm)and body weight (kg) were required. Duplicate patients with multiple ECHO studies were removed, only the first ECHO entry being included. Obvious data entry errors were removed (e.g. height 1866 cm, or weight 8.6 kg). Ideal weight was calculated using the Devine formula, ideal weight = Constant + 2.3x[height in inches-60], where constant= 50kg in males and 45.5kg in females. Body surface area in m2 was calculated = [√(height in cm x weight in Kg)/3600]. The paired t-test was used to determine differences between means. A p value of <0.05 was considered significant. RESULTS There were 47,761 ECHO studies entered into the database, of which 46,605 (98%) had all the required fields completed. Once duplicates were removed (-15,903) and erroneous data deleted (-158, 0.33%), 30,536 remained. There were 16,160 females aged 58.7 ± 19.2 years, with a mean height of 161.7 ± 7.2cm and 14,376 males aged 59.8 ± 19.2 years, with a mean height of 176.7 ± 7.6 cm. There were statistically significant differences in both men and women between actual and ideal weight and actual and ideal BSA, see Table 1. CONLUSIONS. For all ECHO measurements where the value is frequently indexed a decision needs to be made to either use the actual BSA or the ideal BSA. It may be more practical to use the ideal BSA which will remain consistent throughout follow up. Using our data any such measurement for females could be multiplied by 1.16 and for males 1.11 (i.e. actual BSA/ideal BSA). It is disappointing to find that, on average, females are 20 kilograms and males 18 kilograms above their ideal weight. Table 1. Weight females (kg) Weight males (kg) BSA females (m2) BSA males (m2) Number. 16,160 14,376 16,160 14,376 Actual. 73.2 ± 18.9 89.1 ± 19.3 1.80 ± 0.24 2.08 ± 0.24 Ideal. 53.4 ± 6.5 71.4 ± 6.9 1.55 ± 0.13 1.87 ± 0.3 P value. <0.0001 <0.0001 <0.0001 <0.0001 BSA = Body surface area.

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
M Cases ◽  
T Zhu ◽  
U Jurt ◽  
D Brouillard ◽  
M Matangi

Abstract INTRODUCTION The current obesity epidemic has an impact on calculated BSA. Obesity significantly increases the calculated BSA from what the ideal BSA would be if based on a patient’s ideal body weight. PURPOSE To determine the effect of ideal BSA on AV area index in patients with moderate aortic stenosis and normal left ventricular function. METHODS Our ECHO database was searched for all patients with an LVEF >50% and moderate aortic stenosis based on a mean aortic gradient of 20-39 mmHg and an AV area >1.00 cm2. Patients with more than mild aortic regurgitation, previous valvular repair or replacement, significant mitral valve disease or any LV wall motion abnormalities were excluded. Ideal weight was calculated using the Devine formula = Constant + 2.3 x [height in inches-60], where constant= 50Kg in males and 45.5Kg in females). Body surface area in m2 was calculated using the formula = [√ (height in cm x weight in Kg)/3600]. The paired t-test was used to determine differences between means and the Fisher’s exact test was used to determine differences between proportions. A p value of <0.05 was considered significant. RESULTS There were 210 females (mean age 75.4 ± 11.9 years, mean AV gradient 25.3 ± 4.8 mmHg, mean AVA 1.28 ± 0.27 cm2) and 385 males (mean age 72.7 ± 11.3 years, mean AV gradient 25.9 ± 5.2 mmHg, mean AVA 1.32 ± 0.28 cm2). Other important variables are seen in table 1. There were highly significant differences between actual and ideal measurements of weight, BSA and AV area index. Based on the actual BSA there were 151 of 385 male patients (39.2%) with severe aortic stenosis (<0.60 cm2/m2), which dropped to 66 of 385 patients (17.1%) when the ideal BSA was used in the calculation (P < 0.0001, Fisher’s exact test). For females there were 44 of 210 patients with severe aortic stenosis (21.0%) which dropped to 3 (1.4%) when the ideal BSA was used in the calculation (P < 0.0001, Fisher’s exact test). CONCLUSIONS Use of the ideal BSA, based on ideal weight, significantly reclassifies women in terms of AS severity and will be consistent throughout time. All mean aortic gradients and AV areas, by definition, and 98.6% of the ideal AV area indices being in the moderate AS range. The data is less compelling in males but is still significantly improved with 82.9% of AV area indices being correctly assigned. Table 1. Weight/kg (Females) Weight/kg (Males) BSA/m2 (Females) BSA/m2 (Males) AVAI (Females) AVAI (Males) Actual. 77.5 ± 21.4 90.1 ± 16.9 1.79 ± 0.23 2.04 ± 0.20 0.72 ± 0.16 0.65 ± 0.14 Ideal. 51.6 ± 6.2 69.3 ± 7.1 1.51 ± 0.12 1.83 ± 0.14 0.85 ± 0.17 0.73 ± 0.16 P value. <0.0001 <0.0001 <0.0001 <0.0001 <0.0001 <0.0001 AVAI = Aortic valve area index (cm2/m2). BSA = Body surface area (m2).


2013 ◽  
Vol 26 (7) ◽  
pp. 724-733 ◽  
Author(s):  
Kyota Fukazawa ◽  
Yoshitsugu Yamada ◽  
Seigo Nishida ◽  
Taizo Hibi ◽  
Kris L. Arheart ◽  
...  

2010 ◽  
Vol 18 (2) ◽  
pp. 216-225 ◽  
Author(s):  
Kyota Fukazawa ◽  
Seigo Nishida ◽  
Alex Volsky ◽  
Andreas G. Tzakis ◽  
Ernesto A. Pretto

2021 ◽  
Author(s):  
Solomon Demissie ◽  
Prasad Mergu ◽  
Teshale Fikadu ◽  
Tadios Hailu ◽  
Getachew Abebe ◽  
...  

Abstract Introduction: The spleen is a vital lymphoid soft organ that demands constant attention from the clinical point of view. It is multi-dimensional organs that enlarge in all dimensions in disease conditions. The detection of the spleen by palpation on physical examination is not an approval of an enlarged spleen because an unenlarged spleen may palpable. Therefore, this study aimed to assess the Morphometry of spleen dimensions and its correlates among individuals living in Arba Minch Town by sonographic examinations.Methods and Materials: Community-based cross-sectional study was conducted in Arba Minch town from February 1 to March 30, 2020. A multi-stage systematic and simple random sampling technique was applied to select study participants. Data was entered into Epi-Data version 3.1software and exported to SPSS version 20 software for analysis.Result: A total of 708 individuals, 390 (55.1%) males and 318 (44.9 %) females were included in the current study. The mean splenic length, width, thickness and volume were 10.24 cm, 4.79 cm, 3.93 cm, and 109.34 cm³, respectively. The mean spleen length, width, thickness and volumes among males were 10.64 cm, 4.92 cm, 4.05 cm and 119.81 cm³ and among females were 9.75 cm, 4.63 cm, 3.78 cm and 96.50 cm³ respectively. Significant negative correlations were found between age and spleen dimensions. Significant positive correlations were observed between spleen dimensions and height, weight, Body Mass Index, and Body Surface area. But, the correlation between width and body mass index was non-significant (p-value > 0.05).Conclusion and Recommendations: The spleen dimensions were higher in males than females and have a significant positive correlation with height, weight, Body Mass Index and Body Surface Area except for the width. Further studies in different parts of the country have to be done to have normative data on the dimension of Spleen in Ethiopia.


1996 ◽  
Vol 76 (05) ◽  
pp. 682-688 ◽  
Author(s):  
Jos P J Wester ◽  
Harold W de Valk ◽  
Karel H Nieuwenhuis ◽  
Catherine B Brouwer ◽  
Yolanda van der Graaf ◽  
...  

Summary Objective: Identification of risk factors for bleeding and prospective evaluation of two bleeding risk scores in the treatment of acute venous thromboembolism. Design: Secondary analysis of a prospective, randomized, assessor-blind, multicenter clinical trial. Setting: One university and 2 regional teaching hospitals. Patients: 188 patients treated with heparin or danaparoid for acute venous thromboembolism. Measurements: The presenting clinical features, the doses of the drugs, and the anticoagulant responses were analyzed using univariate and multivariate logistic regression analysis in order to evaluate prognostic factors for bleeding. In addition, the recently developed Utrecht bleeding risk score and Landefeld bleeding risk index were evaluated prospectively. Results: Major bleeding occurred in 4 patients (2.1%) and minor bleeding in 101 patients (53.7%). For all (major and minor combined) bleeding, body surface area ≤2 m2 (odds ratio 2.3, 95% Cl 1.2-4.4; p = 0.01), and malignancy (odds ratio 2.4, 95% Cl 1.1-4.9; p = 0.02) were confirmed to be independent risk factors. An increased treatment-related risk of bleeding was observed in patients treated with high doses of heparin, independent of the concomitant activated partial thromboplastin time ratios. Both bleeding risk scores had low diagnostic value for bleeding in this sample of mainly minor bleeders. Conclusions: A small body surface area and malignancy were associated with a higher frequency of bleeding. The bleeding risk scores merely offer the clinician a general estimation of the risk of bleeding. In patients with a small body surface area or in patients with malignancy, it may be of interest to study whether limited dose reduction of the anticoagulant drug may cause less bleeding without affecting efficacy.


Author(s):  
Shirazu I. ◽  
Theophilus. A. Sackey ◽  
Elvis K. Tiburu ◽  
Mensah Y. B. ◽  
Forson A.

The relationship between body height and body weight has been described by using various terms. Notable among them is the body mass index, body surface area, body shape index and body surface index. In clinical setting the first descriptive parameter is the BMI scale, which provides information about whether an individual body weight is proportionate to the body height. Since the development of BMI, two other body parameters have been developed in an attempt to determine the relationship between body height and weight. These are the body surface area (BSA) and body surface index (BSI). Generally, these body parameters are described as clinical health indicators that described how healthy an individual body response to the other internal organs. The aim of the study is to discuss the use of BSI as a better clinical health indicator for preclinical assessment of body-organ/tissue relationship. Hence organ health condition as against other body composition. In addition the study is `also to determine the best body parameter the best predict other parameters for clinical application. The model parameters are presented as; modeled height and weight; modelled BSI and BSA, BSI and BMI and modeled BSA and BMI. The models are presented as clinical application software for comfortable working process and designed as GUI and CAD for use in clinical application.


2015 ◽  
Vol 18 (3) ◽  
pp. 098
Author(s):  
Cem Arıtürk ◽  
Serpil Ustalar Özgen ◽  
Behiç Danışan ◽  
Hasan Karabulut ◽  
Fevzi Toraman

<p class="p1"><span class="s1"><strong>Background:</strong> The inspiratory oxygen fraction (FiO<sub>2</sub>) is usually set between 60% and 100% during conventional extracorporeal circulation (ECC). However, this strategy causes partial oxygen pressure (PaO<sub>2</sub>) to reach hyperoxemic levels (&gt;180 mmHg). During anesthetic management of cardiothoracic surgery it is important to keep PaO<sub>2</sub> levels between 80-180 mmHg. The aim of this study was to assess whether adjusting FiO<sub>2</sub> levels in accordance with body temperature and body surface area (BSA) during ECC is an effective method for maintaining normoxemic PaO<sub>2</sub> during cardiac surgery.</span></p><p class="p1"><span class="s1"><strong>Methods:</strong> After approval from the Ethics Committee of the University of Acıbadem, informed consent was given from 60 patients. FiO<sub>2</sub> adjustment strategies applied to the patients in the groups were as follows: FiO<sub>2</sub> levels were set as 0.21 × BSA during hypothermia and 0.21 × BSA + 10 during rewarming in Group I; 0.18 × BSA during hypothermia and 0.18 × BSA + 15 during rewarming in Group II; and 0.18 × BSA during hypothermia and variable with body temperature during rewarming in Group III. Arterial blood gas values and hemodynamic parameters were recorded before ECC (T1); at the 10th minute of cross clamp (T2); when the esophageal temperature (OT) reached 34°C (T3); when OT reached 36°C (T4); and just before the cessation of ECC (T5).</span></p><p class="p1"><span class="s1"><strong>Results:</strong> Mean PaO<sub>2</sub> was significantly higher in Group I than in Group II at T2 and T3 (<em>P</em> = .0001 and <em>P</em> = .0001, respectively); in Group I than in Group III at T1 (<em>P</em> = .02); and in Group II than in Group III at T2, T3, and T4 <br /> (<em>P</em> = .0001 for all). </span></p><p class="p1"><span class="s1"><strong>Conclusion: </strong>Adjustment of FiO<sub>2</sub> according to BSA rather than keeping it at a constant level is more appropriate for keeping PaO<sub>2</sub> between safe level limits. However, since oxygen consumption of cells vary with body temperature, it would be appropriate to set FiO<sub>2</sub> levels in concordance with the body temperature in the <br /> rewarming period.</span></p>


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