scholarly journals Daily Physical Activity Patterns: A Window on Cognitive Decline in the Baltimore Longitudinal Study of Aging (BLSA)

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 445-445
Author(s):  
Fangyu Liu ◽  
Hang Wang ◽  
Jacek Urbanek ◽  
Yang An ◽  
Eleanor Simonsick ◽  
...  

Abstract Gradual disengagement from essential daily physical activity (PA) necessary for independent living could signal present or emerging mild cognitive impairment (MCI) or Alzheimer’s disease (AD). We used BLSA data to examine whether PA patterns including: 1) total activity counts/day, 2) minutes/day spent active, and 3) activity fragmentation (reciprocal of the mean active bout length) differs between participants with adjudicated normal cognition (n=498) and MCI/AD diagnoses (n=32). Linear models were used and adjusted for demographics, APOE-e4 status, morbidity, and gait speed. Compared to those with normal cognition, those with MCI/AD had 3.0% higher activity fragmentation (SE=1.1%, p=0.006) but similar mean total activity counts/day (p=0.08) and minutes/day spent active (p=0.19). Results suggest that activity fragmentation may arise as a compensatory strategy in the absence of reduced activity in MCI and early AD and that activity monitoring may be potentially useful for detecting MCI and AD at an earlier stage.

2021 ◽  
pp. 204589402199995
Author(s):  
Layse Nakazato Lima ◽  
Felipe Mendes ◽  
Ilma Paschoal ◽  
Daniela Oliveira ◽  
Marcos Mello Moreira ◽  
...  

Pulmonary arterial hypertension (PAH) impairs exercise tolerance and daily physical activity (PA). Aside from the hemodynamic limitations, physical, cognitive and emotional factors may play a relevant and as yet unexplored role. We investigated whether there is an association between the PA level and psychological disorders, health-related quality of life, and daily activities. We also searched for an association of the PA level with clinical factors and functional capacity. This was an analytical, cross-sectional, observational study conducted in a Brazilian University Hospital. Twenty stable PAH subjects wore an accelerometer for a week and completed an activity diary. They answered the quality of life questionnaire (SF-36), as well as the anxiety and depression scale (HADS), and the Manchester Respiratory Activities of Daily Living questionnaire (MRADL). Transthoracic echocardiography, the 6-Minute walk test (6MWT), the 1-minute sit-to-stand test (STST), and spirometry were performed. For statistical analysis we used Chi-square tests or Fisher's test as appropriate and the Mann-Whitney test to compare numerical values between two groups. The relationship between the parameters was assessed using the Spearman correlation test. The mean age was 44.3 years, 80% were women, 80% had idiopathic PAH, and 20% had connective tissue disease . The mean daily step count was 4,280 ± 2,351, and the mean activity time was 41.6 ± 19.3 minutes. The distance covered (6MWT) was 451.5 m, and the number of movements (1-STST) was 23.8. Thirty percent scored positive for anxiety, and 15% for depression (HADS). There was a significant correlation between accelerometer data and walking distance (6MWT), number of movements (1-STST), level of daily physical activity (MRADL), and depression symptoms. Our findings support the hypothesis that other aspects beyond physical and hemodynamic ones might impact the daily physical activity of patients with PAH.


2012 ◽  
Vol 42 (2) ◽  
pp. 222-229 ◽  
Author(s):  
Nanna Yr Arnardottir ◽  
Annemarie Koster ◽  
Dane R. Van Domelen ◽  
Robert J. Brychta ◽  
Paolo Caserotti ◽  
...  

Sensors ◽  
2018 ◽  
Vol 18 (9) ◽  
pp. 3056 ◽  
Author(s):  
Ying Cheung ◽  
Pei-Yun Hsueh ◽  
Ipek Ensari ◽  
Joshua Willey ◽  
Keith Diaz

Owing to advances in sensor technologies on wearable devices, it is feasible to measure physical activity of an individual continuously over a long period. These devices afford opportunities to understand individual behaviors, which may then provide a basis for tailored behavior interventions. The large volume of data however poses challenges in data management and analysis. We propose a novel quantile coarsening analysis (QCA) of daily physical activity data, with a goal to reduce the volume of data while preserving key information. We applied QCA to a longitudinal study of 79 healthy participants whose step counts were monitored for up to 1 year by a Fitbit device, performed cluster analysis of daily activity, and identified individual activity signature or pattern in terms of the clusters identified. Using 21,393 time series of daily physical activity, we identified eight clusters. Employment and partner status were each associated with 5 of the 8 clusters. Using less than 2% of the original data, QCA provides accurate approximation of the mean physical activity, forms meaningful activity patterns associated with individual characteristics, and is a versatile tool for dimension reduction of densely sampled data.


2017 ◽  
Vol 6 ◽  
Author(s):  
D. G. Thomas ◽  
M. Post ◽  
G. Bosch

AbstractObesity levels in cats are increasing and the main causative factor is higher energy intake v. energy expenditure over time. Therefore, altering energy expenditure by enhancing physical activity of the cat could be a strategy to reduce obesity. Hydrating commercial dry diets with water increased activity in cats; however, no study has compared this approach with feeding high-moisture canned diets. Eight healthy male neutered domestic shorthair cats were fed four different dietary treatments in a Latin square design. Treatments were a canned diet ‘as is’ (82 % moisture) and freeze-dried (4 %), a dry diet ‘as is’ (3 %) and with added water (70 %). Cat activity was measured continuously using Actical® accelerometers. Cats were group housed during the first 14 d of each period and then moved to individual cages for 7 d with faecal and urine production measured over the final 4 d. Intake was similar for each diet. The average activity over 24 h was not different between treatments (P > 0·05). However, the ratio between average activity during the day v. at night was higher when cats were fed the dry diet (P = 0·030). Total water intake and urine volume increased when the canned diet was fed (P < 0·001). The similarity in total activity of the cats on the treatments indicates that dietary moisture or diet type did not have a major effect on these cats. However, the stronger diurnal activity patterns observed in the cats when they were fed the dry diet are intriguing and require further study.


2000 ◽  
Vol 32 (Supplement) ◽  
pp. S481-S488 ◽  
Author(s):  
GREGORY J. WELK ◽  
JEROME A. DIFFERDING ◽  
RAYMOND W. THOMPSON ◽  
STEVEN N. BLAIR ◽  
JIM DZIURA ◽  
...  

1991 ◽  
Vol 3 (4) ◽  
pp. 300-309 ◽  
Author(s):  
Chris Riddoch ◽  
Craig Mahoney ◽  
Niamh Murphy ◽  
Colin Boreham ◽  
Gordon Cran

The aim of this study was to provide objective data on the cardiopulmonary fitness and physical activity patterns of Northern Irish postprimary schoolchildren. Forty-five children (23 boys, 22 girls), ages 11-16 years, took part in this study. Each child performed a laboratory test of peak aerobic power (PVO2) and had his/her heart rate monitored for up to 4 school days. The mean values of PVO2 in both boys and girls were in keeping with previous literature. No significant difference was observed between boys and girls in terms of total activity (>50% PVO2), but boys engaged in significantly more vigorous activity (>70% PVO2 than girls did (p<0.05). Younger boys engaged in significantly more vigorous activity than both older boys (p<0.01) and younger girls (p<0.05). A significant negative correlation was found between age and total activity for boys (r= −0.476, p<0.05), but not for girls (r= -0.173, n.s.). The surprisingly low levels of physical activity on the part of older children of both sexes are a cause for concern.


2016 ◽  
Vol 37 (10) ◽  
pp. 1852-1861 ◽  
Author(s):  
E J Shiroma ◽  
M A Schepps ◽  
J Harezlak ◽  
K Y Chen ◽  
C E Matthews ◽  
...  

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