scholarly journals Development of a Staff Informant Measure of Lucidity

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 48-48
Author(s):  
Jeanne Teresi ◽  
José Luchsinger ◽  
Mildred Ramirez ◽  
Stephanie Silver ◽  
Davangere Devanand ◽  
...  
Keyword(s):  
Thematic Analysis ◽  
Reduction Method ◽  
Measure Development ◽  
Time Of Day ◽  
Semantic Relationship ◽  
Conceptual Content ◽  
Web Based ◽  
Group Type ◽  
Relationship Of ◽  
Qualitative Analyses

Abstract Lucidity Measure Development: An existing questionnaire measuring lucidity length, degree, content, coinciding circumstances, and time from lucid episode to death was expanded to include time of day, expressive and receptive communication and speech the month prior to and during the lucid event. Pilot Study: 33 interviews with staff were conducted; 73% reported ever witnessing paradoxical lucidity. Among 29 events reported, 31% lasted several days, 20.7%, 1 day, and 24.1% less. In 78.6% the patient engaged in unexpected activity. 20% died within 3 days and 17% within 3 months after the event. Qualitative Analyses: To refine the measure, 10 family caregivers and 20 LTSS staff caregivers completed a web-based focus-group type exercise using QualtricsXM. A content-thematic analysis with an inductive approach was applied to make qualitative inferences by analyzing the meaning and semantic relationship of words, phrases, and concepts. Using the reduction method of selection, conceptual content categories will be developed.

ACCESS TO AND CONTROL OVER LAND AS GENDERED: CONTEXTUALIZING WOMEN’S ACCESS AND OWNERSHIP RIGHTS OF LAND IN RURAL GHANA

2016 ◽  
Vol 45 (2) ◽  
pp. 28-48 ◽  
Author(s):  
Isaac Dery
Keyword(s):  
Thematic Analysis ◽  
Rural Women ◽  
Rural Poor ◽  
Rural Ghana ◽  
Secure Access ◽  
Key Factor ◽  
Access Rights ◽  
Ownership Rights ◽  
And Control ◽  
Relationship Of

Women’s access to and control over productive resources, including land, has increasingly been recognized in global discussions as a key factor in reducing poverty, ensuring food security and promoting gender equality. Indeed, this argument has been widely accepted by both feminists and development theorists since the 1980s. Based on qualitative research with 50 purposively selected men and women, this study explored the complexity of women’s access to and control over land within a specific relationship of contestations, negotiations, and manipulations with men. Data were analyzed using thematic analysis. While theoretically, participants showed that women’s [secure] access to and control over land has beneficial consequences to women themselves, households and the community at large, in principle, women's access and control status was premised in the traditional framework which largely deprives women, equal access and/or control over the land. The study indicates that even though land is the most revered resource and indeed, the dominant source of income for the rural poor, especially women, gender-erected discrimination and exclusion lie at the heart of many rural women in gaining access to land. This study argues that women's weak access rights and control over land continue to perpetuate the feminization of gender inequality–while men were reported to possess primary access and control over land as the heads of households, women were argued to have secondary rights due to their ‘stranger statuses’ in their husbands’ families. Overall, the degree of access to land among women was reported to be situated within two broad contexts–marriage and inheritance.

scholarly journals Multiomics Analysis Reveals that GLS and GLS2 Differentially Modulate the Clinical Outcomes of Cancer

2019 ◽  
Vol 8 (3) ◽  
pp. 355 ◽  
Author(s):  
Subbroto Saha ◽  
S.M. Islam ◽  
M. Abdullah-AL-Wadud ◽  
Saiful Islam ◽  
Farman Ali ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Methylation Status ◽  
Prognostic Biomarkers ◽  
Functional Protein ◽  
Poor Overall Survival ◽  
Web Based ◽  
Human Cancers ◽  
Multivariate Survival ◽  
Protein Partners ◽  
Relationship Of

Kidney-type glutaminase (GLS) and liver-type glutaminase (GLS2) are dysregulated in many cancers, making them appealing targets for cancer therapy. However, their use as prognostic biomarkers is controversial and remains an active area of cancer research. Here, we performed a systematic multiomic analysis to determine whether glutaminases function as prognostic biomarkers in human cancers. Glutaminase expression and methylation status were assessed and their prominent functional protein partners and correlated genes were identified using various web-based bioinformatics tools. The cross-cancer relationship of glutaminases with mutations and copy number alterations was also investigated. Gene ontology (GO) and pathway analysis were performed to assess the integrated effect of glutaminases and their correlated genes on various cancers. Subsequently, the prognostic roles of GLS and GLS2 in human cancers were mined using univariate and multivariate survival analyses. GLS was frequently over-expressed in breast, esophagus, head-and-neck, and blood cancers, and was associated with a poor prognosis, whereas GLS2 overexpression implied poor overall survival in colon, blood, ovarian, and thymoma cancers. Both GLS and GLS2 play oncogenic and anti-oncogenic roles depending on the type of cancer. The varying prognostic characteristics of glutaminases suggest that GLS and GLS2 expression differentially modulate the clinical outcomes of cancers.

scholarly journals Migraine progression in subgroups of migraine based on comorbidities

Neurology ◽  
2019 ◽  
Vol 93 (24) ◽  
pp. e2224-e2236 ◽  
Author(s):  
Richard B. Lipton ◽  
Kristina M. Fanning ◽  
Dawn C. Buse ◽  
Vincent T. Martin ◽  
Lee B. Hohaia ◽  
...  
Keyword(s):  
Chronic Migraine ◽  
Episodic Migraine ◽  
Study Data ◽  
Continuous Variables ◽  
Web Based ◽  
Symptom Severity Scale ◽  
Hazard Ratios ◽  
Cutaneous Allodynia ◽  
Risk Of Progression ◽  
Relationship Of

ObjectiveTo test the hypothesis that statistically defined subgroups of migraine (based on constellations of comorbidities and concomitant conditions; henceforth comorbidities), previously identified using Chronic Migraine Epidemiology and Outcomes (CaMEO) Study data, differ in prognosis, as measured by rates of progression from episodic migraine (EM) to chronic migraine (CM).MethodsThe onset of CM was assessed up to 4 times over 12 months in individuals with EM and ≥1 comorbidity at baseline, based on constellations of comorbidities (comorbidity classes). The “fewest comorbidities” class served as reference. Individuals completing ≥1 follow-up survey from the web-based CaMEO Study were included. Covariates included sociodemographic variables and headache characteristics. Sex, income, cutaneous allodynia, and medication overuse were modeled as binary variables; age, body mass index, headache-related disability (Migraine Disability Assessment [MIDAS]), and Migraine Symptom Severity Scale as continuous variables. CM onset was assessed using discrete time analysis.ResultsIn the final sociodemographic model, all comorbidity classes had significantly elevated hazard ratios (HRs) for risk of progression to CM from EM, relative to fewest comorbidities. HRs for CM onset ranged from 5.34 (95% confidence interval [CI] 3.89–7.33; p ≤ 0.001) for most comorbidities to 1.53 (95% CI 1.17–2.01; p < 0.05) for the respiratory class. After adjusting for headache covariates independently, each comorbidity class significantly predicted CM onset, although HRs were attenuated.ConclusionsSubgroups of migraine identified by comorbidity classes at cross-section predicted progression from EM (with ≥1 comorbidity at baseline) to CM. The relationship of comorbidity group to CM onset remained after adjusting for indicators of migraine severity, such as MIDAS.Clinicaltrials.gov identifierNCT01648530.

scholarly journals Experiences of Obsessive-Compulsive Disorder

2016 ◽  
Vol 26 (14) ◽  
pp. 2009-2023 ◽  
Author(s):  
Olivia Knapton
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Thematic Analysis ◽  
The Body ◽  
The Self ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Qualitative Thematic Analysis ◽  
Relationship Of ◽  
The Relationship

Obsessive-compulsive disorder (OCD) is a mental health problem characterized by persistent obsessions and compulsions. This article provides insights into experiences of OCD through a qualitative, thematic analysis performed on a set of interviews with people with OCD. Four themes were found as central in the participants’ descriptions of OCD episodes: (a) space, (b) the body, (c) objects, and (d) interactions. The findings also show that episodes of OCD can be grouped into three broad categories: (a) activity episodes, which revolve around everyday tasks; (b) state episodes, which are concerned with the self and identity; and (c) object episodes, which are concerned with the effects of objects on the self. The relationship of this three-way classification of OCD episodes to existing cognitive models of OCD is discussed. The study also demonstrates the value of categorizing episodes, rather than people, into subtypes of OCD so that intra-participant variation can be highlighted.

The Violent Victimization of Children, Adolescents, Adults, and the Elderly: Situational Characteristics and Victim Injury

2017 ◽  
Vol 32 (2) ◽  
pp. 342-361
Author(s):  
James D. Kelsay ◽  
Marie Skubak Tillyer ◽  
Rob Tillyer ◽  
Jeffrey T. Ward
Keyword(s):  
Reporting System ◽  
Age Groups ◽  
The Elderly ◽  
Time Of Day ◽  
Violent Victimization ◽  
Situational Characteristics ◽  
Relationship Of

This study explores the nature and outcome of violent incidents experienced by child, adolescent, adult, and elderly victims. Data from the National Incident-Based Reporting System (NIBRS) are used to determine whether there are differences in the situational characteristics—including location, time of day, weapons, and the victim–offender relationship—of violent victimization experiences across the 4 age groups, including whether situational characteristics influence the likelihood of victim injury. Results indicate that victim injury is most prevalent among adult victims and that the situational characteristics of violent incidents vary by victim age, as do the correlates of victim injury. These findings suggest that of the nature of violent victimization should be examined within the context of victim age, and supports research by scholars who have proposed a model of developmental victimology to identify age-specific victimization patterns.

Temporal dependency and the syntax of subjects

2001 ◽  
Vol 37 (2) ◽  
pp. 287-312 ◽  
Author(s):  
ELLEN THOMPSON
Keyword(s):  
Natural Language ◽  
Relative Clauses ◽  
Semantic Representation ◽  
Main Clause ◽  
Semantic Relationship ◽  
Main Claim ◽  
Syntactic Position ◽  
Relationship Of ◽  
Reconstruction Effects

This article explores the interface between the syntactic and semantic representation of natural language with respect to the interpretation of time. The main claim of the paper is that the semantic relationship of temporal dependency requires syntactic locality at LF. Based on this claim, I explore the syntax and semantics of gerundive relative clauses. I argue that since gerundive relatives are temporally dependent on the tense of the main clause, they need to be local with a temporal element of the main clause at LF. I show that gerundive relatives receive different temporal interpretations depending on their syntactic position at LF. This analysis sheds light on the behavior of gerundive relatives in constructions involving coordination, existential there, scope of quantificational and cardinality adverbials, extraposition, presuppositionality effects and binding-theoretic reconstruction effects.

scholarly journals Sequential Voicing in Old Japanese

2020 ◽  
Vol 12 (5) ◽  
pp. 239
Author(s):  
Wenchao Li
Keyword(s):  
Semantic Relationship ◽  
Compound Nouns ◽  
Old Japanese ◽  
Relationship Of

This study tackles sequential voicing in Old Japanese with a focus on three matters: (a) the interaction of the eight vowels and aspirated consonants; (b) the association of the written system and sequential voicing; and (c) the interaction between the combinationality of each constituent and sequential voicing. Four hundred and seventy-two compound nouns of Old Japanese were collected from the corpus ‘The Japanese Lexicon: A Rendaku Encyclopedia’ by NINJAL. The findings reveal that (i) /k/ has the largest token number of sequential voicing and /p/ has the second largest token number, followed by /s/ and /t/; (ii) regarding the eight vowels /a/, /e1/, /e2/, /i1/, /i2/, /o1/, /o2/ and /u/, /a/ is most likely to form a [N1-N2] whose initial consonant is /k/, /p/ and /t/. It is not likely for the vowel /a/ to invite a voiced ‘/s/-initial’ N1’; /o1/ and /o2/ are both likely to combine with a voiced consonant /k/; /t/ and are less likely to yield a voiced /s/; /e1/ is more likely to invite a voiced consonant than /e2/, but /e1/ does not invite a voiced /p/; /e2/ does not yield a voiced /s/; and /i1/ is likely to take a voiced consonant than /i2/. /k/ and /t/ are the two consonants that are most likely to be voiced when forming a N-N with N1 ends with /i1/. /i2/ does not invite a voiced /p/, /s/ or /t/; /u/ never results in a voiced /s/; (iii) there is a split in the characters that renders a voiced phoneme or an unvoiced phoneme; and (iv) the semantic relationship of N1 and N2 in [N1-N2] that bears sequential voicing is of six types, of which the most frequent relationship of N1 and N2 is [Modifier - N2]. The [prefix-N2] construction is not subject to sequential voicing. 

scholarly journals Player-Character Relationship and Game Satisfaction in Narrative Game: Focus on Player Experience of Character Switch in The Last of Us Part II

2021 ◽  
Vol 12 ◽  
Author(s):  
Valérie Erb ◽  
Seyeon Lee ◽  
Young Yim Doh
Keyword(s):  
Thematic Analysis ◽  
Player Experience ◽  
Meaningful Connections ◽  
Relationship Of ◽  
Depth Interviews

While player characters (PCs) are the key element in engaging players in narrative games, the experience and relationship of the player with the PC have received scarce attention from the perspective of the subjective player experience. The diversity of players and the importance of the PC in the game suggests meaningful connections between how players relate to their PC and the resulting satisfaction with the game. We, therefore, investigated in this study how the player-character relationship influences satisfaction of the player with the game. We performed semi-structured in-depth interviews with 12 players of The Last of Us Part II, a game that has elicited highly polarized reactions in relation to how players responded to a switch of the PC in the game. Through thematic analysis, three themes were found, illustrating the connection between aspects of the player-character relationship and the overall game satisfaction. The themes are “Tolerance of forced character switch”, “Malleability of character image” and “Flexibility of character attachment”. We discuss how those findings should be taken into consideration when designing diverse and meaningful gaming experiences.

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