scholarly journals 475Machine learning approach: identifying the impact of heatwaves and air quality on children’s health

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Dimpalben Patel ◽  
Le Jian ◽  
JianGuo Xiao ◽  
Janis Jansz ◽  
Grace Yun ◽  
...  

Abstract Background Heatwaves, air pollution and their effects on children’s health can vary temporally and spatially. With the emergence of advanced methods such as machine learning, there is an opportunity to improve prediction of children’s health events associated with those exposures. Methods Daily records on emergency department attendances (EDA) for children <15 years, heatwaves, landscape fire burns and air pollutants (CO, SO2, NO2, O3, PM10, PM2.5) were collected for Western Australia, 2006-2015. Decision tree, random forest (RF) and geographical RF (GRF) were compared to predict EDA, identify important risk factors and locations at elevated risk. Validation was performed by comparing actual and predicted EDA. Results RF was the best model with the lowest root mean squared error (MSE). The best RF validation model had an r-squared (R2) =0.95. The percentage increase in MSE indicated that PM10 and PM2.5 were important predictors of EDA for all children. Number of burns was more important in 5-9 year age group than other groups. GRF models (R2 0.90-0.98) showed that heatwave and PM2.5 were the important predictors in southern part of the study area for all age groups. Conclusions The importance of risk factors to predict EDA was varied by age groups and locations. Such differences are important when developing targeted health promotion strategies tailored to age groups and geographical locations. Key messages RF predicted EDA better than other models. Evaluation of spatial variation of heatwave and air quality effects on EDA for children by GRF modelling is useful to identify at risk geographical locations.

2020 ◽  
Vol 1 (1) ◽  
pp. 84-92
Author(s):  
Andrii Shipko ◽  
Serhii Shklyar ◽  
Oleksii Demikhov ◽  
Henryk Dzwigol

This paper summarizes the arguments and counterarguments within the scientific discussion on the factors that influence public health service. The main purpose of this research is to determine the expected indicators of pathogenic and sanogenic effects on significant risk factors of pathology among children. For achieving the research goal, the authors substantiated the models of final results for the modification of risk factors. Investigation of antenatal and genealogical factors in healthy and ill children groups was performed using a specially compiled expert assessment card and parents’ interviews. The systemic population modeling methods were applied to develop and substantiate population health management models (early diagnosis and primary prevention). Evaluation of the expected effectiveness of the N-factor program of primary prevention was carried out on a set of genealogical and antenatal factors. Conducted logical analysis of the methodology of quantitative and qualitative determination of health and the gathered experience in that respect were taken into account in developing population models of preventive effects. This study provides the identified priority directions for realizing the regional and population programs to implement them further. The authors presented the example of calculating the expected effectiveness of children’s health management by eliminating the investigated factors. The authors determine the priority directions for realizing the regional and population programs pathology based on the influence on the various elements to improve the public health services system. An example of calculating the expected effectiveness of children’s health management by eliminating these factors is given. The obtained results could be used to further research the issues associated with a prospective assessment of the program’s effectiveness in reducing the impact of antenatal and genealogical factors on children’s health.


2021 ◽  
Author(s):  
Grainne Colligan ◽  
Ivelina Tsocheva ◽  
James Scales ◽  
Jasmine Chavda ◽  
Rosamund Dove ◽  
...  

AbstractIntroductionAir pollution harms health across the life course. Children are at particular risk of adverse effects during development, which may impact on health in later life. Interventions that improve air quality are therefore urgently needed not only to improve public health now, but to prevent longer-term increased vulnerability to chronic disease. Low Emission Zones are a public health policy intervention aimed at reducing traffic-derived contributions to urban air pollution, but evidence that they deliver clear health benefits is lacking. We established a natural experiment design study (CHILL: Children’s Health in London and Luton) to evaluate the impacts of the introduction of London’s Ultra Low Emission Zone (ULEZ) on children’s health.Methods and analysisCHILL is a prospective two-arm parallel longitudinal cohort study of children aged 6-9 years, attending primary schools in Central London (the focus of the first phase of the ULEZ) and Luton (a comparator site). The primary goal of the study is to examine the impact of changes in annual air pollutant exposures as oxides of nitrogen, nitrogen dioxide, particulate matter less than 2.5microns and 10microns (NOx, NO2, PM2.5, PM10 respectively) across the two sites on lung growth, measured as forced expiratory volume in one second (FEV1) and forced vital capacity (FVC), over four consecutive years. Secondary outcomes being investigated include a range of respiratory health indicators as well as inequality and health economic measures.Ethics and disseminationEthics approval has been given by Queen Mary University of London Research Ethics Committee (ref 2018/08). Dissemination will target audiences through a variety of channels, including research papers, conference and media presentations, web summaries and social media. CHILL is funded by National Institute for Health Research (NIHR) Public Health Research (Ref 16/139/09) with additional funding by Natural Environment Research Council, NIHR CLAHRC North Thames, NIHR ARC North Thames, and the Mayor of London. ClinicalTrials.gov: NCT04695093Strengths and limitations of this studyStrengthsCHILL uses a prospective parallel cohort design, allowing robust conclusions to be drawn on the impact of the ULEZ - a major city-wide air quality mitigation strategy - on air quality and children’s respiratory health.CHILL study cohorts include children from large and ethnically diverse populations living in urban areas characterised by poor air quality.LimitationsAttrition of study cohort population over time, although this has been accounted for in the original design of the study.Potential diminution of the ULEZ air pollution signal due to pre-compliance with ULEZ restrictions in the run up to the introduction of the scheme in Central London on the 8th April 2019, and minor impacts of other pollution mitigation measures.Added complexity of accounting for effects of COVID-19 and related lockdowns on traffic flows, air quality and children’s health.


Author(s):  
Lilian Messias Sampaio Brito ◽  
Luis Paulo Gomes Mascarenhas ◽  
Deise Cristiane Moser ◽  
Ana Cláudia Kapp Titski ◽  
Monica Nunes Lima Cat ◽  
...  

DOI: http://dx.doi.org/10.5007/1980-0037.2016v18n6p678 The aim of this study was to investigate the impact of physical activity (PA) and cardiorespiratory fitness (CRF) levels on the prevalence of overweight and high blood pressure levels in adolescents. In this observational, cross-sectional study, 614 boys aged 10-14 years were assessed for height, body mass, body mass index (BMI), waist circumference (WC) and blood pressure (BP). CRF was assessed using a run test (Léger Test) and subjects were then grouped according to their CRF level. PA level was assessed through a questionnaire (The Three Day Physical Activity Recall) and classified into two groups, namely > 300 minutes of PA/week and < 300 minutes of PA/week. Maturational stage was evaluated according to the development of pubic hair (self-assessment) as proposed by Tanner. We used statistical descriptive analysis, univariate and multivariate analyses in the total participants and subjects were divided by age. Fifty percent of the sample performed < 300 minutes of PA/week and 67.6% had unsatisfactory CRF levels. There was a higher prevalence of unsatisfactory CRF levels among subjects with altered BMI (overweight), WC (abdominal obesity) or BP (high blood pressure) for all age groups. PA history, however, did not show any significance. A total of 31% of participants were overweight, 24.8% had abdominal obesity and 15.4% had increased BP. Unsatisfactory CRF levels were found to be a better predictor for the diagnosis of cardiovascular diseases (CV) risk factors than PA history, regardless of age group. 


2021 ◽  
Vol 1 (2) ◽  
pp. 045-055
Author(s):  
Maria Saridi ◽  
Aikaterini Toska ◽  
Dimitra Latsou ◽  
Sofia Karakousi ◽  
Eleni Albani ◽  
...  

Aim: The aim of the study was to investigate the effect of physical activity and indoor environment on preschool children’s health. Subject and Methods: The final sample comprised 126 parents of children of preschool age. An anonymous questionnaire was used in order to investigate the impact of indoor air pollution on the children's health. Data analysis was performed by using descriptive statistics and cross-tabulations with the SPSS 22.0. Results: The majority of the parents were female (87.3%) at an average age of 31-40 years (73%). Regarding the children, there were an almost equal number of boys and girls and their age ranged between 3 and 6 years old. The children had not shown any signs of emotional or behavioural problems or other issues regarding regular physical functions and they hadn’t shown any problems regarding recreational activities and interaction with friends (90.5%). Cough is a frequent symptom in the case of a common cold (85.7%). There were no statistically significant differences in the parents' responses as far as their children's health dimensions, concerning the availability of an air conditioner at home, the existence of pets and smoking habits in the family environment. Conclusions: Improving air quality is an extremely complicated issue, since pollutants may be created both indoors and outdoors, which makes it very difficult to decrease them. Yet it still is definitely necessary, given the negative effects of pollution on human health, especially on the more vulnerable groups, such as children.


2013 ◽  
Vol 58 (2) ◽  
pp. 239-247 ◽  
Author(s):  
Zhiwei Xu ◽  
Perry E. Sheffield ◽  
Hong Su ◽  
Xiaoyu Wang ◽  
Yan Bi ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Uta Düesberg ◽  
Julia Wosniok ◽  
Lutz Naehrlich ◽  
Patience Eschenhagen ◽  
Carsten Schwarz

Abstract Airway inflammation and chronic lung infections in cystic fibrosis (CF) patients are mostly caused by bacteria, e.g. Pseudomonas aeruginosa (PA). The role of fungi in the CF lung is still not well elucidated, but evidence for a harmful and complex role is getting stronger. The most common filamentous fungus in CF is Aspergillus fumigatus (AF). Age and continuous antibiotic treatment have been discussed as risk factors for AF colonisation but did not differentiate between transient and persistent AF colonisation. Also, the impact of co-colonisation of PA and AF on lung function is still under investigation. Data from patients with CF registered in the German Cystic Fibrosis Registry database in 2016 and 2017 were retrospectively analysed, involving descriptive and multivariate analysis to assess risk factors for transient or persistent AF colonisation. Age represented an independent risk factor for persistent AF colonisation. Prevalence was low in children less than ten years, highest in the middle age and getting lower in higher age (≥ 50 years). Continuous antibiotic lung treatment was significantly associated with AF prevalence in all age groups. CF patients with chronic PA infection had a lower lung function (FEV1%predicted), which was not influenced by an additional AF colonisation. AF colonisation without chronic PA infection, however, was significantly associated with a lower function, too. Older age up to 49 years and continuous antibiotic use were found to be the main risk factors for AF permanent colonisation. AF might be associated with decrease of lung function if not disguised by chronic PA infection.


2018 ◽  
Vol 93 ◽  
pp. 390-396
Author(s):  
Katie A. Ports ◽  
Whitney L. Rostad ◽  
Feijun Luo ◽  
Michelle Putnam ◽  
Elizabeth Zurick

Sign in / Sign up

Export Citation Format

Share Document