scholarly journals PSIII-1 Activity of nucleolar organizers depending on genotype

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 235-236
Author(s):  
Pavel Klenovitskiy ◽  
Baylar S Iolchiev ◽  
Anastasia N Vetokh
Keyword(s):  
Higher Education ◽  
Venous Blood ◽  
Nucleolar Organizer ◽  
Endogenous Factors ◽  
Functional Load ◽  
Blood Smears ◽  
Nucleolar Organizers ◽  
Microscopic Studies ◽  
Nucleolar Apparatus ◽  
The Relationship

Abstract The level of protein proliferation and biosynthesis in various physiological and pathological processes depends on the functional activity in the nucleolar apparatus of cell. The activity degree of the nucleolar organizers varies depending on the level of functional load on the cells. It is associated with the exogenous and endogenous factors and the manifestation of polygenic traits, such as the synthesis intensity of subunits rRNA (18S and 28S) that enter the ribosome. The aim of this research was to study the relationship between the activity of nucleolar organizers and the animal genotype. The objects of study were goats with different genotypes divided by 3 groups of goats hybrids were used: group_I was 5 individuals of Karachay × F1(C.sibirica×C.hircus); group_II - 4 individuals of Boer × F1; group_III - 3 individuals of F2(C.sibirica×C.hircus) × F1. The material for the study was venous blood. Blood smears were fixed with Lillie’s solution and were stained using the Havel and Blake technique. Microscopic studies were performed using a Nikon Eclipse Ni equipped with Nikon DS-Qi2 camera (4908×3264). For statistical analysis of the obtained data, the SPSSv.23 was used. We used the average optical density AgNOR (DNOR) as an indicator reflecting the total amount of Ag bound to the argyrophilic proteins of the nucleolar organizer, It was found that in goats of the second group this indicator was 158.58±10.18, which was significantly inferior in terms of AgNOR to animals in group_I (211.10±3.62) and in group_III (206.77±4.43). No significant differences between the goats of groups I and III were found. Thus, the AgNOR criterion depends on the goat genotype to a certain extent and is of interest for assessing the activity of the nucleolar organizers in goats. Supported by RFBR project №20-016-00116А and the Ministry of Science and Higher Education of Russia (№АААА-А18-118021590132-9).

scholarly journals CYTOPLASMIC MALE STERILITY IN NICOTIANA, RESTORATION OF FERTILITY, AND THE NUCLEOLUS. II. N. DEBNEYI CYTOPLASM

Genetics ◽  
1978 ◽  
Vol 90 (1) ◽  
pp. 151-159
Author(s):  
J A Burns ◽  
D U Gerstel ◽  
S A Sand
Keyword(s):  
Cytoplasmic Male Sterility ◽  
Male Sterility ◽  
Pollen Fertility ◽  
Preceding Paper ◽  
Nucleolar Organizer ◽  
Nicotiana Species ◽  
Nucleolar Organizers ◽  
Nucleolar Apparatus ◽  
Mother Cells ◽  
Restoration Of Fertility

ABSTRACT Previously, it was shown that a fragment chromosome, apparently derived from the Nicotiana repanda chromosomal complement, restores to normal the morphology and fertility of the abortive and feminized anthers produced by plants that possess the N. tabacum genome in cytoplasm from N. repanda. Furthermore, that restorer chromosome organizes the nucleolus and inhibits the nucleolus-forming activity of the nucleolar organizers of N. tabacum chromosomes present in the same cells, particularly in pollen mother cells. To determine whether these relations are basic or only coincidental, restorer chromosomes for other cytoplasms are now being investigated. The present paper describes a study of a chromosome, presumably derived from N. debneyi, with partial restoring power. Acting in the cytoplasm of N. debneyi, it directs formation of morphologically normal anthers, without, however, restoring pollen fertility. We find that this chromosome also has a functioning nucleolar organizer, but only slightly inhibits the nucleolus-forming capacity of N. tabacum chromosomes. The suggestion of a relationship between the nucleolar apparatus and restoration of normal anthers is thus strengthened by the observation that restorers are found on nucleolus-forming chromosomes from two very distinct Nicotiana species, as well as in several comparable cases cited from the Triticinae. The manner in which the nucleolus, or its organizer, may direct defeminization and restoration of anther morphology is not known; suggestions were offered in the preceding paper in this series (Gerstel, Burns and Burk 1978).

Ultrastructure and the relationship between the nucleolus and the nucleolar organizer region in Orthoptera male germ cells

1985 ◽  
Vol 27 (2) ◽  
pp. 186-191 ◽  
Author(s):  
P. Esponda ◽  
J. S. Rufas ◽  
S. Fonzo ◽  
J. Gosálvez
Keyword(s):  
Germ Cells ◽  
Organizer Region ◽  
Nucleolar Organizer Region ◽  
Nucleolar Organizer ◽  
Serial Sections ◽  
Male Germ Cells ◽  
Fibrillar Center ◽  
Nucleolar Organizers ◽  
The Relationship

The ultrastructure of the nucleolus and the nucleolar organizer region, together with the relationships they maintain, are described in male germ cells of two species of grasshoppers. The nucleolus is multiple and appears related to a fibrillar center which seems to represent only a nontranscribing part of the organizer region. By means of serial sections, a particular relationship among the fibrillar center, the rDNA loops, and the nucleolar masses is suggested.Key words: ultrastructure, nucleolar organizers, nucleolus, Orthoptera.

The next generation: Experiences of higher educated Turkish-Dutch on The Hague labour market

2014 ◽  
Vol 11 (2) ◽  
pp. 206-217
Author(s):  
Karijn G. Nijhoff
Keyword(s):  
Higher Education ◽  
Qualitative Study ◽  
Labour Market ◽  
Education System ◽  
Minority Groups ◽  
Personal Characteristics ◽  
Market Positioning ◽  
The Hague ◽  
The Relationship ◽  
Dutch City

This paper explores the relationship between education and labour market positioning in The Hague, a Dutch city with a unique labour market. One of the main minority groups, Turkish-Dutch, is the focus in this qualitative study on higher educated minorities and their labour market success. Interviews reveal that the obstacles the respondents face are linked to discrimination and network limitation. The respondents perceive “personal characteristics” as the most important tool to overcoming the obstacles. Education does not only increase their professional skills, but also widens their networks. The Dutch education system facilitates the chances of minorities in higher education through the “layering” of degrees. 

1. The Neoliberal Logic of Service-Learning

2020 ◽  
Vol 2 (1) ◽  
pp. 1-18 ◽  
Author(s):  
Megan Snider Bailey
Keyword(s):  
Higher Education ◽  
Service Learning ◽  
Teaching And Learning ◽  
Community Partnerships ◽  
Market Forces ◽  
Community Based ◽  
University Partnerships ◽  
Economic Changes ◽  
The Public ◽  
The Relationship

<?page nr="1"?>Abstract This article investigates the ways in which service-learning manifests within our neoliberal clime, suggesting that service-learning amounts to a foil for neoliberalism, allowing neoliberal political and economic changes while masking their damaging effects. Neoliberalism shifts the relationship between the public and the private, structures higher education, and promotes a façade of community-based university partnerships while facilitating a pervasive regime of control. This article demonstrates that service-learning amounts to an enigma of neoliberalism, making possible the privatization of the public and the individualizing of social problems while masking evidence of market-based societal control. Neoliberal service-learning distances service from teaching and learning, allows market forces to shape university-community partnerships, and privatizes the public through dispossession by accumulation.

A University Education

2017 ◽  
Author(s):  
David Willetts
Keyword(s):  
Higher Education ◽  
Modern Society ◽  
University Education ◽  
Modern World ◽  
Controversial Issues ◽  
The Us ◽  
The Individual ◽  
The University ◽  
First Time ◽  
The Relationship

Universities have a crucial role in the modern world. In England, entrance to universities is by nation-wide competition which means English universities have an exceptional influence on schools--a striking theme of the book. This important book first investigates the university as an institution and then tracks the individual on their journey to and through university. In A University Education, David Willetts presents a compelling case for the ongoing importance of the university, both as one of the great institutions of modern society and as a transformational experience for the individual. The book also makes illuminating comparisons with higher education in other countries, especially the US and Germany. Drawing on his experience as UK Minister for Universities and Science from 2010 to 2014, the author offers a powerful account of the value of higher education and the case for more expansion. He covers controversial issues in which he was involved from access for disadvantaged students to the introduction of L9,000 fees. The final section addresses some of the big questions for the future, such as the the relationship between universities and business, especially in promoting innovation.. He argues that the two great contemporary trends of globalisation and technological innovation will both change the university significantly. This is an authoritative account of English universities setting them for the first time in their new legal and regulatory framework.

The Effects of Religion and Modernization on Egyptian Women’s IPV Attitudes

2021 ◽  
pp. 107780122097880
Author(s):  
Golshan Golriz ◽  
Skye Miner
Keyword(s):  
Higher Education ◽  
Intimate Partner Violence ◽  
Latent Class Analysis ◽  
Significant Relationship ◽  
Partner Violence ◽  
Latent Class ◽  
Intimate Partner ◽  
Wife Beating ◽  
Multinomial Regression ◽  
The Relationship

This article uses the 2008 Egypt Demographic and Health Survey to explore the relationship between religion and women’s attitudes toward intimate partner violence (IPV). It also asks whether modernization, as measured by having a higher education or living in an urban area, can mediate or moderate this relationship. Using latent class analysis to create categories of women’s wife-beating attitudes, and multinomial regression to explore the relationship between religion, education, and urbanity, we find no significant relationship between being Muslim and justifying wife beating. Our data further suggest that neither education nor urbanity mediate or moderate this relationship.

scholarly journals Relationship between 24-h venous blood glucose variation and mortality among patients with acute respiratory failure

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xiaoling Zhang ◽  
Jingjing Zhang ◽  
Jiamei Li ◽  
Ya Gao ◽  
Ruohan Li ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Respiratory Failure ◽  
Hospital Mortality ◽  
Acute Respiratory Failure ◽  
Venous Blood ◽  
Sensitivity Analyses ◽  
Icu Mortality ◽  
Logistic Regression Models ◽  
The Mean ◽  
The Relationship

AbstractEvidence indicates that glucose variation (GV) plays an important role in mortality of critically ill patients. We aimed to investigate the relationship between the coefficient of variation of 24-h venous blood glucose (24-hVBGCV) and mortality among patients with acute respiratory failure. The records of 1625 patients in the Multiparameter Intelligent Monitoring in Intensive Care II (MIMIC II) database were extracted. The 24-hVBGCV was calculated as the ratio of the standard deviation (SD) to the mean venous blood glucose level, expressed as a percentage. The outcomes included ICU mortality and in-hospital mortality. Participants were divided into three subgroups based on tertiles of 24-hVBGCV. Multivariable logistic regression models were used to evaluate the relationship between 24-hVBGCV and mortality. Sensitivity analyses were also performed in groups of patients with and without diabetes mellitus. Taking the lowest tertile as a reference, after adjustment for all the covariates, the highest tertile was significantly associated with ICU mortality [odds ratio (OR), 1.353; 95% confidence interval (CI), 1.018–1.797] and in-hospital mortality (OR, 1.319; 95% CI, 1.003–1.735), especially in the population without diabetes. The 24-hVBGCV may be associated with ICU and in-hospital mortality in patients with acute respiratory failure in the ICU, especially in those without diabetes.

Higher education, post-conflict democratization and the legacies of authoritarian rule: The Tripoli University Programme for Rebuilding Libya

2021 ◽  
pp. 174619792098136
Author(s):  
Sansom Milton
Keyword(s):  
Higher Education ◽  
Middle East ◽  
Civic Education ◽  
Authoritarian Rule ◽  
Post Conflict ◽  
Transitional Processes ◽  
The Arab Spring ◽  
The Relationship

In this paper, the role of higher education in post-uprising Libya is analysed in terms of its relationship with transitional processes of democratization and civic development. It begins by contextualising the Libyan uprising within the optimism of the ‘Arab Spring’ transitions in the Middle East. Following this, the relationship between higher education and politics under the Qadhafi regime and in the immediate aftermath of its overthrow is discussed. A case-study of a programme designed to support Tripoli University in contributing towards democratisation will then be presented. The findings of the case-study will be reflected upon to offer a set of recommendations for international actors engaging in political and civic education in conflict-affected settings, in particular in the Middle East.

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