PSIX-30 Modulating action of fish oil on serum profiles of pigs exposed to prenatal inflammatory signals

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 500-501
Author(s):  
Haley E Rymut ◽  
Marissa R Keever ◽  
Olivia Perez ◽  
Laurie A Rund ◽  
Rodney W Johnson ◽  
...  

Abstract Inflammatory signals elicited in response to stressors during gestation can affect fetal development and can have prolonged postnatal effects in the offspring. The objectives of the present study were to assess the effects of viral infection during gestation on nursed piglets, and to investigate possible modulating effects of fish oil. A total of 36 pigs were studied, distributed across three gilt treatment groups and sexes within treatment group. One-third of the piglets served as reference, being born from gilts that were not exposed to viral infection and receiving a non-supplemented diet. Another third of the piglets were born from gilts that were challenged with porcine reproductive and respiratory virus during the last third of gestation and receiving a non-supplemented diet. The remaining piglets were born from gilts that were challenged with the virus and were supplemented with fish oil (2.5 g of docosahexaenoic acid and eicosapentaeonic acid). All gilts received diets that met nutritional requirements during gestation and lactation (~90% corn and soybean meal). The piglets remained with the gilts and nursed until 22 d of age at which time blood was drawn and the levels of metabolic parameters were measured. The immune challenge during gestation had a significant effect on the level of globulin (P < 0.02). The globulin levels were higher in female piglets from gilts infected during gestation relative to control gilts. The blood level of triglycerides was similar between piglets from reference gilts and viral-infected gilts supplemented with fish oil, and lower than in piglets from non-supplemented infected gilts. Our results demonstrate that fish oil supplementation can modulate effects of infection during gestation on the piglet. This study is supported by USDA NIFA AFRI, grant number 2018-67015-27413.

2019 ◽  
Vol 17 (1) ◽  

Background: Commercial broiler is a rapidly growing sector in Bangladesh. The broilers are supplied with the balanced ration prepared from a number of ingredients which are not available uniformly throughout the years. On the other hands, manufactured feeds are costly and inconvenient for the rural farmers. This study is undertaken to use unconventional feed ingredients aiming to decrease the broiler production cost. Method: A total of ninety-nine day- old broiler chicks (Hubbard) of either sex were used in this study in 3 treatment groups to assess processed unconventional feed item (shoti, blood meal, poultry dropping and molasses) on growth and profitability upon rearing for 60 days. Broilers were reared in dip litter system and were fed ad libitum on conventional and unconventional diet dividing into 3 treatment diets namely, treatment diet 1 (T1: Conventional as control), treatment diet 2 (T2: unconventional with blood meal and shoti), and treatment diet 3 (T3: unconventional with blood meal, shoti, poultry droppings and molasses) throughout the trial period. Treatment group 1 (T1) was used as control. Results: Broilers fed on control diet (conventional feed) achieved higher (P<0.01) body weight, while the broilers offered diets with the highest amount of unconventional feed had the lowest body weight. Increased (P<0.01) feed intake was observed during 21days and 49 days of age when broilers fed diets with the supplementation, but no significant differences were found among the groups in terms of feed consumption during 33 day of age. FCR differed significantly (P<.01) throughout the trial period with the broilers fed diets without supplementation of unconventional feed item had the superior FCR than the others. Mortality rate was 6.06%,9.09%, and 9.09% in treatment group I, treatment group II, and treatment group III respectively while live weights, feed conversion and feed consumption was unaffected by all the dietary groups with/without incorporation of unconventional feed item up to day 60 days of age. Statistically significant (P<0.01) decreased live weight was observed among the treatment groups in 60-day-old birds. Productivity and cost-benefit analysis were performed. Conclusion: Use of unconventional feed ingredients in broiler production greatly reduces the feed cost with little hampering the growth rate and hence, it is profitable for the farmers.


2020 ◽  
Vol 5 (2) ◽  
pp. 309-318
Author(s):  
Ihwan Ihwan ◽  
◽  
Rahmatia Rahmatia ◽  
Khildah Khaerati ◽  

Teratogenic is an abnormal development on embryo and is the cause of congenital defect or birth defect. This study aims to determine the effect of the addition of Dioscorea alata L. ethanol extracts to the embryo development on pregnant mice whose given orally to 24 mice which divided to 4 treatment groups, they are the normal group (NG) with NaCMC 0.5%; 28 mg/KgBB treatment group; 35 mg/KgBB; 42 mg/Kg BB. The addition of Dioscorea alata L ethanol extracts was done on the sixth day until the 15th day of pregnancy. On the 18th day of pregnancy, Laparaktomi was done to the pregnant mice and the embryo was taken out of the uterus. The observation was done to the fetus numbers, weight weighing of the fetus's body, dan length measurement of the fetus's body. Another observation is the observation of the external organ defect of the embryo. The study results that the addition of Dioscorea alata L ethanol extracts with various doses have no significant effect (P>0.5) to the mice external fetus development. On the examination of the fetus, we can conclude that Dioscorea alata L ethanol extracts don’t give any effect that may cause the defect of the fetus’ external organ.


2012 ◽  
Vol 8 (3) ◽  
pp. 196-205
Author(s):  
Massimo F.L. Pomponi ◽  
Massimiliano Pomponi ◽  
Giovanni Gambassi

2019 ◽  
Vol 8 (6) ◽  
pp. 823
Author(s):  
Hsiao-Fen Hsu ◽  
Chia-Chan Kao ◽  
Ti Lu ◽  
Jeremy C. Ying ◽  
Sheng-Yu Lee

The current study explored the differences in the effectiveness of first and second generation long-acting injections and orally administered antipsychotics in reducing the rehospitalization rate among patients with schizophrenia receiving home care services in a medical center in Southern Taiwan. Longitudinal data between 1 January 2006, and 31 December 2015, were collected retrospectively. Patients were classified into three treatment groups: First generation antipsychotic (FGA) long-acting injection (LAI), second generation antipsychotic long-acting injection (SGA) (LAI), and oral antipsychotics. The primary outcomes were the rehospitalization rate and the follow-up time (duration of receiving home care services) until psychiatric rehospitalization. A total of 78 patients with schizophrenia were recruited. The average observation time was about 40 months. The oral treatment group tended to be older with a higher number of female patients and a lower level of education. The FGA treatment group tended to have a higher frequency and duration of hospitalization before receiving home care services. We found no significant differences in the follow-up time or psychiatric rehospitalization rate after receiving home care services among the three treatment groups. We propose that oral and LAI antipsychotics were equally effective when patients received home care services. Our results can serve as a reference for the choice of treatment for patients with schizophrenia in a home care program.


1989 ◽  
Vol 44 (1) ◽  
pp. 17-23
Author(s):  
E. Rillaerts ◽  
K. Van Camp ◽  
M.F. Vandewoude ◽  
F. Rademakers ◽  
I. De Leeuw

2021 ◽  
Author(s):  
Laerke Sass ◽  
Elín Bjarnadóttir ◽  
Jakob Stokholm ◽  
Bo Chawes ◽  
Rebecca K. Vinding ◽  
...  

1999 ◽  
Vol 1999 ◽  
pp. 176-176
Author(s):  
A.R. Peters ◽  
L.A. Dwyer ◽  
A. Dawson ◽  
P.A. Canham ◽  
J.D. Mackinnon

The problem of seasonal infertility in pigs has been recognised for many years. The infertility complex can may be manifested by increased returns to service, prolonged weaning to oestrus intervals and decreased litter size. The purpose of this trial was to evaluate the effects of Buserelin treatment on fertility in sows and gilts during the seasonally infertile period.A total of 1231 mixed parity sows and gilts from five outdoor herds in East Anglia were randomly assigned to one of three treatment groups. Any sows not presented for service at first post weaning oestrus were excluded. All sows and gilts judged to be in adequate health and condition to be kept in a commercial breeding herd were included. Group C sows and gilts were given no treatment. Group R1 sows and gilts were injected i.m. with 8μg Buserelin (2.0ml Receptal; Hoechst Roussel Vet UK Ltd) on the day of service.


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