PSII-19 Stallion exposure fails to alter circulating LH concentrations or hasten ovulation in seasonally anestrous mares

Abstract Introduction of males to seasonally anestrous females has been shown to increase LH concentrations and hasten the first ovulation in ewes and does. Investigation of the male effect in mares has not been well-studied. The objective of this study was to determine if direct or indirect exposure to a stallion would result in a similar increase in LH and hasten first ovulation in anestrous mares. In late February, mares were stratified by parity and age and randomly assigned to 3 treatments (n = 7 per treatment): DXP (direct exposure; mares housed adjacent to stallion and allowed direct contact for 2 h on 3 d/wk by placing the stallion into a cage in the center of a tease pen), IXP (indirect exposure; mares housed adjacent to stallion but not allowed direct contact), and CON (control; mares housed away from stallion and not allowed direct or indirect exposure). During the first, third, and fifth days of treatment, blood was collected hourly for 8 h beginning just before treatment initiation for later analysis of LH. Concentrations of LH were analyzed for repeated measures and time from the first day of treatment to ovulation was analyzed using one-way ANOVA. The interval from treatment initiation to first ovulation did not differ (P > 0.05) among treatments: 36.3±6.7, 36.9±6.7, and 48.3±4.2 d for DXP, IXP, and CON, respectively. Although treatments did not affect (P > 0.05) LH concentration, a significant day effect (P < 0.05) was detected with LH concentrations being greater on the fifth treatment day compared with the first and third days. Results signify that stallion exposure to anestrous mares failed to elicit the same effects that have been observed in short-day breeders, thus indicating that stallion exposure may not be beneficial in the management of anestrous mares.

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Association between ibrutinib treatment and hypertension

Heart ◽

10.1136/heartjnl-2021-319110 ◽

2021 ◽

pp. heartjnl-2021-319110

Author(s):

Dae Hyun Lee ◽

Fahad Hawk ◽

Kieun Seok ◽

Matthew Gliksman ◽

Josephine Emole ◽

...

Keyword(s):

Blood Pressure ◽

Systolic Blood Pressure ◽

Repeated Measures ◽

Treatment Initiation ◽

Kinase Inhibitor ◽

Pressure Change ◽

Exact Test ◽

N 93 ◽

Pressure Changes ◽

Over Time

BackgroundIbrutinib is a tyrosine kinase inhibitor most commonly associated with atrial fibrillation. However, additional cardiotoxicities have been identified, including accelerated hypertension. The incidence and risk factors of new or worsening hypertension following ibrutinib treatment are not as well known.MethodsWe conducted a retrospective study of 144 patients diagnosed with B cell malignancies treated with ibrutinib (n=93) versus conventional chemoimmunotherapy (n=51) and evaluated their effects on blood pressure at 1, 2, 3 and 6 months after treatment initiation. Descriptive statistics were used to compare baseline characteristics for each treatment group. Fisher’s exact test was used to identify covariates significantly associated with the development of hypertension. Repeated measures analyses were conducted to analyse longitudinal blood pressure changes.ResultsBoth treatments had similar prevalence of baseline hypertension at 63.4% and 66.7%, respectively. There were no differences between treatments by age, sex and baseline cardiac comorbidities. Both systolic and diastolic blood pressure significantly increased over time with ibrutinib compared with baseline, whereas conventional chemoimmunotherapy was not associated with significant changes in blood pressure. Baseline hypertensive status did not affect the degree of blood pressure change over time. A significant increase in systolic blood pressure (defined as more than 10 mm Hg) was noted for ibrutinib (36.6%) compared with conventional chemoimmunotherapy (7.9%) at 1 month after treatment initiation. Despite being hypertensive at follow-up, 61.2% of patients who were treated with ibrutinib did not receive adequate blood pressure management (increase or addition of blood pressure medications). Within the ibrutinib group, of patients who developed more than 20 mm Hg increase in systolic blood pressure, only 52.9% had hypertension management changes.ConclusionsIbrutinib is associated with the development of hypertension and worsening of blood pressure. Cardiologists and oncologists must be aware of this cardiotoxicity to allow timely management of blood pressure elevations.

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Forefoot Striking Is More Effective in Reducing Loadrates than Increasing Cadence in Runners

Foot & Ankle Orthopaedics ◽

10.1177/2473011418s00054 ◽

2018 ◽

Vol 3 (3) ◽

pp. 2473011418S0005

Author(s):

Erin Futrell ◽

Irene Davis

Keyword(s):

Repeated Measures ◽

Auditory Signal ◽

Gait Retraining ◽

Loading Rates ◽

Impact Forces ◽

Running Injuries ◽

Main Effects ◽

Wireless Accelerometer ◽

One Way Anova ◽

Vertical Impact

Category: Sports Introduction/Purpose: Vertical impact forces are highly influenced by the way the foot contacts the ground. These impact forces are associated with high loading rates which have been related to running injuries. As a result, clinicians have begun to use gait retraining interventions to reduce loadrates and prevent future impact-related injuries. Two types of gait retraining techniques have been promoted to reduce excessive running impacts. The first involves increasing cadence (CAD), or number of steps per minute, by 5-10%, thereby reducing stride length. The second type of gait retraining involves landing on the ball of the foot at ground contact, or using a forefoot strike (FFS). Both of these gait-retraining styles have been reported to reduce impacts, but they have not been compared with each other. Methods: 33 healthy runners (9M, 24F), running 5-15 mpw, with a rearfoot strike pattern with cadence < 170 steps/min were recruited. Subjects were randomly allocated to either FFS or CAD retraining. All subjects underwent an 8-session gait retraining program (over 2-3 wks) with auditory feedback on a treadmill. The CAD group ran to a digital metronome to increase cadence by 7.5%. The FFS group wore a wireless accelerometer that provided an auditory signal on footstrike pattern. A gait analysis was conducted at baseline, 1 wk, 1 month, and 6 months. Variables included vertical average and instantaneous load rates (VALR, VILR). A 2 x 4 repeated measures ANOVA was used to compare differences within and between the CAD and FFS groups at baseline, 1 week, 1 month and 6 months post retraining. For variables with significant interactions, simple main effects of group, as well as time were further explored using one-way ANOVA Results: There were significant interaction effects of time*group for VALR (p= 0.001), VILR (p=0.001) and foot angle (p< 0.001), but not cadence. For the simple main effects for the CAD group, VALR reduced by 14%, 7% and 16% at 1 week, 1 month, and 6 months post gait retraining respectively, compared with baseline (Figure 1). However, these reductions were not significant. For the FFS group, VALR was significantly reduced by 50%, 51% and 51% at 1 week, 1 month, and 6 months post gait retraining respectively. Interestingly, both the CAD and FFS groups increased cadence by similar amounts. Conclusion: Transitioning to a FFS pattern is significantly more effective than increasing CAD when reducing vertical loadrate (both VALR and VILR) is the goal. These changes persisted out to 6 months post gait retraining, suggesting permanence of the new pattern.

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Depth-Related Curing Potential of Ormocer- and Dimethacrylate-Based Bulk-Fill Composites

Materials ◽

10.3390/ma14226753 ◽

2021 ◽

Vol 14 (22) ◽

pp. 6753

Author(s):

Ramona S. Oltramare ◽

Reto Odermatt ◽

Phoebe Burrer ◽

Thomas Attin ◽

Tobias T. Tauböck

Keyword(s):

Double Bond ◽

Repeated Measures ◽

In Vitro Study ◽

High Viscosity ◽

Degree Of Conversion ◽

Double Bond Conversion ◽

Nanohybrid Composite ◽

Post Hoc ◽

One Way Anova

The aim of this in vitro study was to investigate the degree of C=C double bond conversion of high-viscosity dimethacrylate- or ormocer-based bulk-fill composites as a function of measurement depth. Four bulk-fill composites (Tetric EvoCeram Bulk Fill, x-tra fil, SonicFill, and Bulk Ormocer) and the conventional nanohybrid composite Tetric EvoCeram were applied in standardized Class II cavities (n = 6 per group) and photoactivated for 20 s at 1350 mW/cm2. The degree of conversion of the composites was assessed using Fourier-transform infrared spectroscopy at seven measurement depths (0.15, 1, 2, 3, 4, 5, 6 mm). Data were analyzed using repeated measures ANOVA and one-way ANOVA with Bonferroni post-hoc tests (α = 0.05). The investigated bulk-fill composites showed at least 80% of their maximum degree of conversion (80% DCmax) up to a measuring depth of at least 4 mm. Tetric EvoCeram Bulk Fill and Bulk Ormocer achieved more than 80% DCmax up to a measuring depth of 5 mm, x-tra fil up to 6 mm. The conventional nanohybrid composite Tetric EvoCeram achieved more than 80% DCmax up to 3 mm. In contrast to the conventional composite, the investigated ormocer- and dimethacrylate-based bulk-fill composites can be photo-polymerized in thick layers of up to at least 4 mm with regard to their degree of C=C double bond conversion.

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Evaluation of an Innovative Digital Assessment Tool in Dental Anatomy

The Journal of Contemporary Dental Practice ◽

10.5005/jp-journals-10024-1691 ◽

2015 ◽

Vol 16 (5) ◽

pp. 366-371 ◽

Cited By ~ 4

Author(s):

Matt T Lam ◽

So Ran Kwon ◽

Fang Qian ◽

Gerald E Denehy

Keyword(s):

Gold Standard ◽

Repeated Measures ◽

Assessment Tool ◽

T Test ◽

Pearson’S Correlation ◽

Digital Assessment ◽

Dental Anatomy ◽

Significant Difference ◽

Pearson's Correlation ◽

One Way Anova

ABSTRACT Aim The E4D Compare software is an innovative tool that provides immediate feedback to students’ projects and competencies. It should provide consistent scores even when different scanners are used which may have inherent subtle differences in calibration. This study aimed to evaluate potential discrepancies in evaluation using the E4D Compare software based on four different NEVO scanners in dental anatomy projects. Additionally, correlation between digital and visual scores was evaluated. Materials and methods Thirty-five projects of maxillary left central incisors were evaluated. Among these, thirty wax-ups were performed by four operators and five consisted of standard dentoform teeth. Five scores were obtained for each project: one from an instructor that visually graded the project and from four different NEVO scanners. A faculty involved in teaching the dental anatomy course blindly scored the 35 projects. One operator scanned all projects to four NEVO scanners (D4D Technologies, Richardson, TX, USA). The images were aligned to the gold standard, and tolerance set at 0.3 mm to generate a score. The score reflected percentage match between the project and the gold standard. One-way ANOVA with repeated measures was used to determine whether there was a significant difference in scores among the four NEVO scanners. Paired-sample t-test was used to detect any difference between visual scores and the average scores of the four NEVO scanners. Pearson's correlation test was used to assess the relationship between visual and average scores of NEVO scanners. Results There was no significant difference in mean scores among four different NEVO scanners [F(3, 102) = 2.27, p = 0.0852 one-way ANOVA with repeated measures]. Moreover, the data provided strong evidence that a significant difference existed between visual and digital scores (p = 0.0217; a pairedsample t-test). Mean visual scores were significantly lower than digital scores (72.4 vs 75.1). Pearson's correlation coefficient of 0.85 indicated a strong correlation between visual and digital scores (p < 0.0001). Conclusion The E4D Compare software provides consistent scores even when different scanners are used and correlates well with visual scores. Clinical significance The use of innovative digital assessment tools in dental education is promising with the E4D Compare software correlating well with visual scores and providing consistent scores even when different scanners are used. How to cite this article Lam MT, Kwon SR, Qian F, Denehy GE. Evaluation of an Innovative Digital Assessment Tool in Dental Anatomy. J Contemp Dent Pract 2015;16(5):366-371.

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Αξιολόγηση της πρώιμης νευροεξελικτικής παρέμβασης στη νευροαναπτυξιακή πορεία πρόωρων νεογνών υψηλού κινδύνου

10.12681/eadd/28079 ◽

2012 ◽

Author(s):

Μαρία Κυριακίδου

Keyword(s):

Repeated Measures ◽

T Test ◽

Repeated Measures Anova ◽

Kolmogorov Smirnov ◽

One Way Anova

Τα ποσοστά θνητότητας των υψηλού κινδύνου πρόωρων νεογνών έχουν σταθεροποιηθεί και συνεπώς η μελέτη των στρατηγικών μείωσης των υψηλών ποσοστών νευροαναπτυξιακών διαταραχών είναι απαραίτητη. Τα υψηλού κινδύνου πρόωρα νεογνά πρέπει να συμμετέχουν σε προγράμματα πρώιμης παρέμβασης από πολύ νωρίς, λόγω της αυξημένης πλαστικότητας του αναπτυσσόμενου εγκεφάλου. Παρόλα αυτά, η αποτελεσματικότητα της παρέμβασης σε όλα τα ΥΚ πρόωρα νεογνά δεν είναι ξεκάθαρη. Έχει αποδειχτεί, ότι οι πρώιμες αναπτυξιακές παρεμβάσεις που ξεκινούν μετά την έξοδο από το νοσοκομείο, βελτιώνουν τη γνωστική ανάπτυξη των νεογνών αλλά το αποτέλεσμα αυτό δε διατηρείται στη σχολική ηλικία. Η απόδειξη των επιδράσεων της πρώιμης παρέμβασης στην κινητική ανάπτυξη είναι ελλιπής. Επομένως, στόχος της παρούσας μελέτης ήταν να αξιολογήσει την επίδραση της πρώιμης παρέμβασης με τη μέθοδο NDT στη γνωστική και κινητική έκβαση ΥΚ πρόωρων νεογνών, μέχρι τη διορθωμένη ηλικία των 18 μηνών αλλά και να συσχετίσει νεογνικούς και περιγεννηρικούς παράγοντες με τη γνωστική και κινητική έκβαση. Στη μελέτη εισήχθησαν νεογνά με ΔΚ≤32 εβδομάδων και ΒΓ≤1500 γραμμαρίων. Αποκλείστηκαν, νεογνά με χρωματοσωμικές ανωμαλίες, μείζονες συγγενείς ανωμαλίες και γενετικά σύνδρομα. Επίσης, αποκλείστηκαν τα νεογνά που στη διορθωμένη ηλικία των 18 μηνών διαγνώστηκαν με εγκεφαλική παράλυση. Συνολικά, 147 νεογνά πληρούσαν τα κριτήρια εισαγωγής και εφαρμόστηκε η δοκιμασία ΤΙΜΡ στη ΔΗ των 38-41 εβδομάδων. Από αυτά, 73 τυχαιοποιήθηκαν στην ομάδα παρέμβασης και 74 στην ομάδα ελέγχου. Η ομάδα παρέμβασης ακολούθησε πρόγραμμα φυσικοθεραπείας με τη μέθοδο NDT με συχνότητα 2 φορές την εβδομάδα, για ένα έτος ενώ η ομάδα ελέγχου εφάρμοσε πρόγραμμα οδηγιών στο σπίτι 2 φορές την εβδομάδα, για ένα έτος. Στη στατιστική ανάλυση χρησιμοποιήθηκε το t-test, η one-way ANOVA, ο έλεγχος χ² κατά Pearson, repeated measures ANOVA και ο έλεγχος κατά Greenhouse-Geisser. Επιπρόσθετα, χρησιμοποιήθηκε ο έλεγχος Kolmogorov-Smirnov. Το ΒΓ και η ΔΚ των νεογνών στις δύο ομάδες ήταν 1325,18 (±368,46) γρ και 30,55 (±1,6) εβδ, αντίστοιχα, στην ομάδα παρέμβασης και 1440,18 (±293,61) και 30,76 (±1,6) στην ομάδα ελέγχου, αντίστοιχα. Η διαφορά δεν ήταν στατιστικά σημαντική. Οι δύο ομάδες ήταν συγκρίσιμες ως προς τους περιγεννητικούς και νεογνικούς παράγοντες . Οι 2 ομάδες αξιολογήθηκαν στη διορθωμένη ηλικία των 3, 6, 12 και 18 μηνών. Οι δύο ομάδες είχαν στατιστικά σημαντική διαφορά στη διορθωμένη ηλικία των 3, 12 και 18 μηνών στη γνωστική και κινητική έκβαση με την ομάδα παρέμβασης να υπερέχει. Στη διορθωμένη ηλικία των 18 μηνών, η ομάδα παρέμβασης σημείωσε μέση βαθμολογία 108,83 (±9,39) στη γνωστική κλίμακα και 109,01 (±10,30) στην κινητική ενώ η ομάδα ελέγχου 99,18 (±7,31) στη γνωστική και 98,81 (±8,91) στην κινητική κλίμακα της δοκιμασίας Bayley III. Η φυσικοθεραπεία (p<0,0001), η IVH (p<0,0001), η πολυδυμία (p=0,008), η ΝΕΚ (p=0,001) και η διάρκεια χορήγησης Ο₂ (p=0,008) επηρέασαν σημαντικά στη βαθμολογία της γνωστικής έκβασης των πρόωρων νεογνών στη διορθωμένη ηλικία των 18 μηνών. Η φυσικοθεραπεία (p<0,0001), ήταν ο μοναδικός παράγοντας που επηρέασε σημαντικά τη βαθμολογία της κινητικής έκβασης των πρόωρων νεογνών στη διορθωμένη ηλικία των 18 μηνών. Τα ΥΚΠΝ επωφελούνται από το πρόγραμμα πρώιμης παρέμβασης με τη μέθοδο NDT, διότι βελτιώνουν την κινητική και γνωστική τους έκβαση μέχρι τη διορθωμένη ηλικία των 18 μηνών. Ως εκ τούτου, συστήνεται η εφαρμογή της μεθόδου κατά τη διάρκεια του 1ου έτους ζωής ως προληπτικό πρόγραμμα θεραπείας στα ΥΚΠΝ. Αδιαμφισβήτητα, μεγαλύτερης διάρκειας μακροχρόνιες παρακολουθήσεις απαιτούνται για να επιβεβαιώσουν ή να απορρίψουν τη διατήρηση των αποτελεσμάτων στην προσχολική ή σχολική ηλικία. Συστήνεται, ο παράγοντας φυσικοθεραπευτική παρέμβαση να συνυπολογίζεται στις πολυπαραγοντικές αναλύσεις διότι οδηγεί σε αξιόπιστη ερμηνεία των αποτελεσμάτων που αφορούν την έκβαση.

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Limb venous tone and responsiveness in hypertensive humans

Journal of Applied Physiology ◽

10.1152/japplphysiol.90574.2008 ◽

2008 ◽

Vol 105 (3) ◽

pp. 894-901 ◽

Cited By ~ 17

Author(s):

Erin P. Delaney ◽

Colin N. Young ◽

Angela DiSabatino ◽

Michael E. Stillabower ◽

William B. Farquhar

Keyword(s):

Repeated Measures ◽

Muscle Tone ◽

Cold Pressor Test ◽

Cold Pressor ◽

Quadratic Regression ◽

Venous Compliance ◽

Venous Tone ◽

Venous Capacitance ◽

Regression Parameters ◽

One Way Anova

Hypertensive (HTN) animal models demonstrate lower venous compliance as well as increased venous tone and responsiveness compared with normotensive (NTN) controls. However, the extent to which findings in experimental animals can be extended to humans is unknown. Forearm and calf venous compliance were quantified in 9 NTN (23 ± 1 yr) and 9 HTN (24 ± 1 yr) men at baseline, after administration of nitroglycerin (NTG), during a cold pressor test (CP), and post-handgrip exercise ischemia (PEI). Individual pressure-volume relationships from a cuff deflation protocol (1 mmHg/s) were modeled with a quadratic regression. Regression parameters β1 and β2 were used to calculate compliance. A one-way ANOVA was used to compare the beta parameters and a repeated-measures ANOVA was used to compare volumes across all pressures (between groups at baseline and within groups during perturbations). Limb venous compliance was similar between groups (forearm: NTN β1 = 0.11 ± 0.01 and β2 = −0.00097 ± 0.0001, HTN β1 = 0.10 ± 0.01 and β2 = −0.00088 ± 0.0001; calf: NTN β1 = 0.12 ± 0.01 and β2 = −0.00102 ± 0.0001, HTN β1 = 0.11 ± 0.01 and β2 = −0.00090 ± 0.0001). However, at baseline, volume across all pressures (i.e., capacitance) was lower in the forearm ( P ≤ 0.01) and tended to be lower in the calf ( P = 0.08) in HTN subjects. Venous compliance was not altered by any perturbation in either group. Forearm volume was increased during NTG in HTN subjects only. While venous compliance was similar between NTN and HTN adults, HTN adults have lower forearm venous capacitance (volume) which is increased with NTG. These data suggest that young HTN adults may have augmented venous smooth muscle tone compared with NTN controls.

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Metabolomics and Their Ability to Distinguish Thyroid Disorders: A Retrospective Pilot Study

Hormone and Metabolic Research ◽

10.1055/a-0850-9691 ◽

2019 ◽

Vol 51 (04) ◽

pp. 256-260 ◽

Cited By ~ 1

Author(s):

Tristan Struja ◽

Andreas Eckart ◽

Alexander Kutz ◽

Peter Neyer ◽

Marius Kraenzlin ◽

...

Keyword(s):

Treatment Initiation ◽

Disease Type ◽

Thyroid Disorders ◽

Thyroid Disorder ◽

Metabolomic Profile ◽

Anova Analysis ◽

Classical Parameters ◽

Toxic Goiter ◽

Distinct Separation ◽

One Way Anova

AbstractEarly diagnosis of thyroid disorders is key to further treatment. We assessed the ability of a high-throughput proton NMR metabolomic profile to distinguish disease type amongst of Graves’ disease (n=87), Hashimoto’s thyroiditis (n=17), toxic goiter (n=11), and autoimmune thyroiditis [i. e., subacute thyroiditis (n=4), postpartum thyroiditis (n=1)]. This observational study was conducted investigating patients presenting with a thyroid disorder at a Swiss hospital endocrine referral center and an associated endocrine outpatient clinic. The main outcome was diagnosis of thyroid disorder based on classical parameters. Blood draws took place as close as possible to treatment initiation. We performed one-way ANOVA and partial least squares discriminant analysis (PLS-DA) as multivariate classification and feature ranking method. One-way ANOVA analysis yielded following significantly different metabolites, triglycerides in small VLDL, triglycerides in very small VLDL, and triglycerides in large LDL (FDR=0.04). There was no distinct separation of any of the 4 diagnoses by PLS-DA. We did not find a metabolomic biomarker combination capable of predicting diagnosis. Preanalytical issues might have influenced our results. We strongly suggest replicating our work in another cohort.

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Exposure to genocide and the risk of schizophrenia: a population-based study

Psychological Medicine ◽

10.1017/s0033291715002354 ◽

2015 ◽

Vol 46 (4) ◽

pp. 855-863 ◽

Cited By ~ 18

Author(s):

S. Z. Levine ◽

I. Levav ◽

Y. Goldberg ◽

I. Pugachova ◽

Y. Becher ◽

...

Keyword(s):

Cox Regression ◽

Population Based ◽

In Utero ◽

Sensitivity Analyses ◽

Critical Periods ◽

Population Based Study ◽

Regression Modelling ◽

Direct Exposure ◽

The Holocaust ◽

Indirect Exposure

BackgroundNo evidence exists on the association between genocide and the incidence of schizophrenia. This study aims to identify critical periods of exposure to genocide on the risk of schizophrenia.MethodThis population-based study comprised of all subjects born in European nations where the Holocaust occurred from 1928 to 1945, who immigrated to Israel by 1965 and were indexed in the Population Register (N = 113 932). Subjects were followed for schizophrenia disorder in the National Psychiatric Case Registry from 1950 to 2014. The population was disaggregated to compare groups that immigrated before (indirect exposure: n = 8886, 7.8%) or after (direct exposure: n = 105 046, 92.2%) the Nazi or fascist era of persecutions began. The latter group was further disaggregated to examine likely initial prenatal or postnatal genocide exposures. Cox regression modelling was computed to compare the risk of schizophrenia between the groups, adjusting for confounders.ResultsThe likely direct group was at a statistically (p < 0.05) greater risk of schizophrenia (hazard ratio = 1.27, 95% confidence interval 1.06–1.51) than the indirect group. Also, the likely combined in utero and postnatal, and late postnatal (over age 2 years) exposure subgroups were statistically at greater risk of schizophrenia than the indirect group (p < 0.05). The likely in utero only and early postnatal (up to age 2 years) exposure subgroups compared with the indirect exposure group did not significantly differ. These results were replicated across three sensitivity analyses.ConclusionsThis study showed that genocide exposure elevated the risk of schizophrenia, and identified in utero and postnatal (combined) and late postnatal (age over 2 years) exposures as critical periods of risk.

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Effects of mechanical abrasion challenge on sound and demineralized dentin surfaces treated with SDF

Scientific Reports ◽

10.1038/s41598-020-77035-9 ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Mahmoud Sayed ◽

Yuka Tsuda ◽

Khairul Matin ◽

Ahmed Abdou ◽

Kim Martin ◽

...

Keyword(s):

Surface Roughness ◽

Surface Integrity ◽

Repeated Measures ◽

Color Change ◽

Antibacterial Properties ◽

Mechanical Abrasion ◽

Surface Loss ◽

One Way Anova ◽

Demineralized Dentin ◽

Bacterial Effect

AbstractThis study evaluated the effect of mechanical abrasion on the surface integrity, color change (ΔE) and antibacterial properties of demineralized and sound dentin surfaces treated with silver-diammine-fluoride (SDF). The dentin specimens were divided into two groups: sound and demineralized dentin, then divided into three sub-groups, control (no-treatment), SDF, and SDF + potassium-iodide (KI). Each sub-group was further divided into two groups, one exposed to mechanical brushing and the other without brushing. Specimens were analyzed for the ΔE, surface roughness/surface loss and antibacterial properties (CFU, optical density and fluorescent microscope). Repeated Measures ANOVA was used for statistical analysis of color change while one-way ANOVA was used for CFU analysis. SDF and SDI + KI groups showed significant reduction in ΔE with brushing in the sound dentin group unlike the demineralized group. The surface roughness values were higher for both SDF and SDF + KI groups but roughness values significantly decreased after brushing. Both SDF and SDF + KI groups revealed significantly less surface loss than control. The SDF group showed high anti-bacterial effect after brushing, unlike SDF + KI group. So, we concluded that mechanical brushing improved the esthetic outcome. While, SDF and SDF + KI could protect the dentin surface integrity. SDF-treated dentin possesses an antibacterial property even after mechanical brushing.

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Alpha absolute power: motor learning of practical pistol shooting

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2008000300010 ◽

2008 ◽

Vol 66 (2b) ◽

pp. 336-340 ◽

Cited By ~ 11

Author(s):

Clayton Amaral Domingues ◽

Sergio Machado ◽

Emerson Garcia Cavaleiro ◽

Vernon Furtado ◽

Mauricio Cagy ◽

...

Keyword(s):

Motor Learning ◽

Repeated Measures ◽

Healthy Subjects ◽

Learning Task ◽

Alpha Power ◽

Motor Execution ◽

Task Execution ◽

Post Hoc Analysis ◽

Post Hoc ◽

One Way Anova

The present study aimed at investigating changes in behavior (shooting precision) and electrophysiological variables (absolute alpha power) during the motor learning of practical pistol shooting. The sample was composed of 23 healthy subjects, right-handed, male, between 18 and 20 years of age. The task consisted of four learning blocks. A One-way ANOVA with repeated measures and a post hoc analysis were employed to observe modifications on behavioral and electrophysiological measures (p<0.05). The results showed significative differences between blocks according to motor learning, and a significant improvement in shooting's accuracy from both blocks. It was observed a decrease in alpha power in all electrodes examined during task execution when compared with baseline and learning control blocks. The findings suggest that alpha power decreases as the function of the motor learning task when subjects are engaged in the motor execution.

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