scholarly journals Fish Oil–Enriched Nutritional Supplement Attenuates Progression of the Acute-Phase Response in Weight-Losing Patients with Advanced Pancreatic Cancer

1999 ◽  
Vol 129 (6) ◽  
pp. 1120-1125 ◽  
Author(s):  
Matthew D. Barber ◽  
James A. Ross ◽  
Tom Preston ◽  
Alan Shenkin ◽  
Kenneth C. H. Fearon
Keyword(s):  
Pancreatic Cancer ◽  
Fish Oil ◽  
Acute Phase ◽  
Acute Phase Response ◽  
Advanced Pancreatic Cancer ◽  
Nutritional Supplement ◽  
Phase Response

Supplemental fish oil does not alter immune competence or the pathophysiological response to an intramammary infusion of endotoxin in peri-partum multiparous Holstein cows

2009 ◽  
Vol 76 (2) ◽  
pp. 165-172 ◽  
Author(s):  
Michael A Ballou ◽  
Rodrigo C Gomes ◽  
Edward J DePeters
Keyword(s):  
Antimicrobial Activity ◽  
Fish Oil ◽  
Acute Phase ◽  
Whole Blood ◽  
Acute Phase Response ◽  
Post Partum ◽  
Interferon Γ ◽  
Phase Response ◽  
Holstein Cows ◽  
Immune Competence

The objective was to determine the effects of supplementing the diet with fish oil during the peri-partum period on the immune competence and the pathophysiological response to a lipopolysaccharide-induced mastitis challenge. Multiparous Holstein cows (n=30) were completely randomized to one of two treatments at 3 weeks pre-partum. Treatments differed only in the source of supplemental lipid and included either Energy Booster® or fish oil. Treatment diets were fed from −21 d relative to expected date of parturition until 10 d post partum. Treatments were fed as a bolus prior to the a.m. feeding. The dose of lipid during the pre-partum period was 250 g/d, whereas the amount of lipid supplemented post partum was adjusted to the level of intake, approximately 0·92% of the previous day's dry matter intake. Ex-vivo analyses of immune competence were measured including the antimicrobial activity of whole blood against Escherichia coli, Salmonella typhimurium and Candida albicans as well as the production of interferon-γ by peripheral blood mononuclear cultures. At 7 days in milk cows were infused with 100 μg of Esch. coli lipopolysaccharide into one rear quarter. Supplementing fish oil increased plasma concentrations of eicosapentaenoic and docosahexaenoic acids, but had no affect on the proportions of arachidonic acid at calving. Fish oil did not influence the production of interferon-γ or the antimicrobial activity of whole blood against any of the microorganisms. Furthermore, fish oil had no ameliorative effect on either the local or the systemic acute phase response following an intramammary lipopolysaccharide challenge in early lactating Holstein cows. Supplementing fish oil in the diet of peri-partum cows will not protect them from deleterious effects of an excessive acute phase response.

scholarly journals PSX-6 Effect of dietary microalgae and fish oil on the nursery pig acute-phase response.

2018 ◽  
Vol 96 (suppl_3) ◽  
pp. 491-492
Author(s):  
A Lee ◽  
L You ◽  
Z Li ◽  
S Oh ◽  
M Alcorn ◽  
...  
Keyword(s):  
Fish Oil ◽  
Acute Phase ◽  
Acute Phase Response ◽  
Phase Response ◽  
Nursery Pig

Resting energy expenditure, the acute phase response and cytokines in weight-losing patients with pancreatic cancer

1993 ◽  
Vol 12 ◽  
pp. 22
Author(s):  
J.S. Falconer ◽  
C.E. Plester ◽  
J.A. Ross ◽  
M.G. O'Riordain ◽  
D.C. Carter ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Energy Expenditure ◽  
Acute Phase ◽  
Acute Phase Response ◽  
Resting Energy Expenditure ◽  
Phase Response ◽  
Resting Energy

scholarly journals Cytokines, the Acute-Phase Response, and Resting Energy Expenditure in Cachectic Patients with Pancreatic Cancer

1994 ◽  
Vol 219 (4) ◽  
pp. 325-331 ◽  
Author(s):  
J. Stuart Falconer ◽  
Kenneth C. H. Fearon ◽  
Claire E. Plester ◽  
James A Ross ◽  
David C. Carter
Keyword(s):  
Pancreatic Cancer ◽  
Energy Expenditure ◽  
Acute Phase ◽  
Acute Phase Response ◽  
Resting Energy Expenditure ◽  
Phase Response ◽  
Resting Energy

scholarly journals Modifying the Acute Phase Response of Jersey Calves by Supplementing Milk Replacer with Omega-3 Fatty Acids from Fish Oil

2008 ◽  
Vol 91 (9) ◽  
pp. 3478-3487 ◽  
Author(s):  
M.A. Ballou ◽  
G.D. Cruz ◽  
W. Pittroff ◽  
D.H. Keisler ◽  
E.J. DePeters
Keyword(s):  
Fatty Acids ◽  
Fish Oil ◽  
Acute Phase ◽  
Acute Phase Response ◽  
Phase Response ◽  
Milk Replacer ◽  
Omega 3 Fatty Acids ◽  
Omega 3

N-3 polyunsaturated fatty acids do not affect cytokine response to strenuous exercise

2000 ◽  
Vol 89 (6) ◽  
pp. 2401-2406 ◽  
Author(s):  
Anders Dyhr Toft ◽  
Mette Thorn ◽  
Kenneth Ostrowski ◽  
Sven Asp ◽  
Kirsten Møller ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Fish Oil ◽  
Acute Phase ◽  
Acute Phase Response ◽  
Phase Response ◽  
Strenuous Exercise ◽  
Control Group ◽  
Fish Oil Supplementation ◽  
To Receive

The aim of the present study was to investigate whether fish oil supplementation was able to modulate the acute-phase response to strenuous exercise. Twenty male runners were randomized to receive supplementation ( n = 10) with 6.0 g fish oil daily, containing 3.6 g n-3 polyunsaturated fatty acids (PUFA), for 6 wk or to receive no supplementation ( n = 10) before participating in The Copenhagen Marathon 1998. Blood samples were collected before the race, immediately after, and 1.5 and 3 h postexercise. The fatty acid composition in blood mononuclear cells (BMNC) differed between the fish oil-supplemented and the control group, showing incorporation of n-3 PUFA and less arachidonic acid in BMNC in the supplemented group. The plasma levels of tumor necrosis factor-α, interleukin-6, and transforming growth factor-β1 peaked immediately after the run, the increase being 3-, 92-, and 1.1-fold, respectively, compared with resting samples. The level of interlukin-1 receptor antagonist peaked 1.5 h after exercise, with the increase being 87-fold. However, the cytokine levels did not differ among the two groups. Furthermore, supplementation with fish oil did not influence exercise-induced increases in leucocytes and creatine kinase. In conclusion, 6 wk of fish oil supplementation had no influence on the acute-phase response to strenuous exercise.

Pancreatic Cancer as a Model: Inflammatory Mediators, Acute-phase Response, and Cancer Cachexia

1999 ◽  
Vol 23 (6) ◽  
pp. 584-588 ◽  
Author(s):  
Kenneth C.H. Fearon ◽  
Matthew D. Barber ◽  
J.S. Falconer ◽  
Donald C. McMillan ◽  
James A. Ross ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Acute Phase ◽  
Inflammatory Mediators ◽  
Acute Phase Response ◽  
Cancer Cachexia ◽  
Phase Response

scholarly journals Health Benefits of Supplementing Nursery Pig Diets with Microalgae or Fish Oil

Animals ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 80 ◽  
Author(s):  
Alison Lee ◽  
Lan You ◽  
Se-Young Oh ◽  
Ziwei Li ◽  
Alexandra Code ◽  
...  
Keyword(s):  
Fish Oil ◽  
Acute Phase ◽  
Acute Phase Response ◽  
Health Benefits ◽  
Phase Response ◽  
Standard Diet ◽  
Omega 3 ◽  
Phase 3 ◽  
Total N ◽  
Lps Challenge

Weaning stress can negatively impact a pig’s performance; dietary supplementation with omega-3 polyunsaturated fatty acids (n-3 PUFA) reduces inflammatory stress and promotes nursery pig’s health and growth. Fish oil (FO) is a major source of n-3 PUFA; however, microalgae (AL) may provide an alternative source of n-3 PUFA. The aim of this study was to assess the health benefits of supplementing a plant protein-based nursery diet with 3.12% AL or 1.25% FO providing equal total n-3 PUFA compared to a control (CON) diet. Seventy-two pigs were fed experimental diets for three weeks (phases 1 and 2), followed by a common standard diet for three weeks (phase 3). Following phase 2, 8 pigs per treatment underwent a lipopolysaccharide (LPS) immune stress challenge to assess the acute-phase response and 8 pigs per treatment were vaccinated with novel antigens to assess acquired immunity. No significant differences in piglets’ growth were observed, despite decreased feed intake in FO piglets compared to AL piglets in phase 3. AL supplementation tended to reduce, and FO supplementation significantly reduced the LPS-induced fever response. The AL pigs had significantly reduced cortisol responses, increased cytokine concentrations, and increased chromogranin A concentrations compared to FO and CON pigs following LPS challenge. Results suggest that AL or FO supplementation in nursery diets differentially modulate the acute-phase response, possibly due to different n-3 PUFA profiles between the two ingredients.

Albumin synthesis rates, cytokines and the acute phase response in pancreatic cancer

1994 ◽  
Vol 13 ◽  
pp. 33-34
Author(s):  
J.S. Faiconer ◽  
C. Slater ◽  
K.C.H. Fearon ◽  
J.A. Ross ◽  
D.C. McMillan ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Acute Phase ◽  
Acute Phase Response ◽  
Phase Response ◽  
Albumin Synthesis
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