scholarly journals Dietary Modulation of Omega-3/Omega-6 Polyunsaturated Fatty Acid Ratios in Patients With Breast Cancer

1997 ◽  
Vol 89 (15) ◽  
pp. 1123-1131 ◽  
Author(s):  
D. Bagga ◽  
S. Capone ◽  
H.-J. Wang ◽  
D. Heber ◽  
M. Lill ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Omega 3 ◽  
Dietary Modulation ◽  
Omega 6 ◽  
3 Omega

scholarly journals Karakteristik dan Profil Asam Lemak Kombinasi Minyak Ikan Patin dan Minyak Hati Ikan Hiu

2021 ◽  
Vol 24 (1) ◽  
pp. 122-130
Author(s):  
M Lamudin Noor ◽  
Andarini Diharmi ◽  
Rahman Karnila
Keyword(s):  
Fatty Acid ◽  
Saturated Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Unsaturated Fatty Acid ◽  
Omega 3 ◽  
Omega 6

Minyak ikan patin mengandung kadar asam lemak omega-9, tetapi rendah asam lemak omega 3 Minyak hati ikan hiu memiliki kandungan asam lemak omega 3 relatif tinggi. Penelitian ini bertujuan untuk menentukan karakteristik dan sifat kimia minyak ikan patin dan profil asam lemak kombinasi minyak ikan patin dengan hati kan hiu. Metode penelitian eksperimen dengan melakukan ekstraksi lemak perut ikan patin secara dry rendering dihasilkan minyak kasar dan dimurnikan. Minyak ikan patin murni dilakukan pencampuran dengan minyak hati ikan hiu. dengan perbandingan 1:1, 2:1 dan 2:1. Parameter analisis terdiri atas karakteristik kimia (bilangan asam lemak bebas (ALB),bilangan  asam, peroksida, iod,  p-anisidin, penyabunan, total oksida/totox), dan profil asam lemak. Hasil penelitian menunjukkan bahwa kombinasi  minyak patin dan hati ikan hiu dihasilkan karakteristik kimia terdiri atas asam lemak bebas sebesar 1,59-2,19%, bilangan asam 2,86-3,00 mg KOH/g, peroksida 15,50-18,32 meq/kg, iod 63,46-84,42 gI2/100g), p-anisidin 21,53-24,16, penyabunan 142,21-162,28 mg KOH/g dan TOTOX 53,33-69,43. Hasil analisis komposisi asam lemak jenuh (saturated fatty acid/SAFA) dihasilkan  asam palmitat tertinggi,  asam lemak tak jenuh tunggal  (mono unsaturated fatty acid/MUFA)  asam oleat,  dan asam lemak tak jenuh ganda (polyunsaturated fatty acid/PUFA)  asam linoleat. Hasil analisis karakteristik kimia kombinasi  minyak ikan patin dan hati ikan hiu sesuai dengan standar IFOMA. Kombinasi minyak hati ikan hiu dan ikan patin dengan perbandingan (2:1) dihasilkan kandungan omega 3 dan omega 6 sebesar 2,59 % dan 29,75%.

scholarly journals Aryl Hydrocarbon Receptor-Dependent inductions of omega-3 and omega-6 polyunsaturated fatty acid metabolism act inversely on tumor progression

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Sara Huerta-Yepez ◽  
Ana Tirado-Rodriguez ◽  
Mayra R. Montecillo-Aguado ◽  
Jun Yang ◽  
Bruce D. Hammock ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Tumor Progression ◽  
Aryl Hydrocarbon Receptor ◽  
Polyunsaturated Fatty Acid ◽  
Fatty Acid Metabolism ◽  
Acid Metabolism ◽  
Omega 3 ◽  
Aryl Hydrocarbon ◽  
Omega 6

scholarly journals Effect of different dietary omega-3/omega-6 fatty acid ratios on reproduction in male rats

2013 ◽  
Vol 12 (1) ◽  
pp. 33 ◽  
Author(s):  
Lin Yan ◽  
Xiao-long Bai ◽  
Zheng-feng Fang ◽  
Lian-qiang Che ◽  
Sheng-yu Xu ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Male Rats ◽  
Omega 3 ◽  
Omega 6 ◽  
3 Omega

scholarly journals Adipose Tissue Omega-3 and Omega-6 Fatty Acid Content and Breast Cancer in the EURAMIC Study

1998 ◽  
Vol 147 (4) ◽  
pp. 342-352 ◽  
Author(s):  
N. Simonsen ◽  
P. v. Veer ◽  
J. J. Strain ◽  
J. M. Martin-Moreno ◽  
J. K. Huttunen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adipose Tissue ◽  
Fatty Acid ◽  
Acid Content ◽  
Fatty Acid Content ◽  
Omega 3 ◽  
Omega 6

Relationship between omega-3 and omega-6 fatty acid ratios and breast cancer

Nutrition ◽  
1997 ◽  
Vol 13 (9) ◽  
pp. 822-824 ◽  
Author(s):  
Stefani L. Capone ◽  
Dilprit Bagga ◽  
John A. Glaspy
Keyword(s):  
Breast Cancer ◽  
Fatty Acid ◽  
Omega 3 ◽  
Omega 6

scholarly journals Monohydroxylated fatty acid substrate specificity of human leukocyte 5-lipoxygenase and ω-hydroxylase

1988 ◽  
Vol 256 (3) ◽  
pp. 879-883 ◽  
Author(s):  
M Guichardant ◽  
M Lagarde
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Substrate Specificity ◽  
Calcium Ionophore ◽  
Hydroxy Derivative ◽  
Ionophore A23187 ◽  
Omega 3 ◽  
Double Bonds ◽  
Omega 6 ◽  
3 Omega

Various monohydroxylated fatty acids were synthesized from eicosapolyenoic acids, namely arachidonic (20:4 omega-6), timnodonic (20:5 omega-3), dihomogammalinolenic (20:3 omega-6) and mead (20:3 omega-9) acids. 12-Hydroxy derivatives, as well as 12-hydroxy-5,8,10-heptadecatrienoic acid (HHT), were produced with platelets as the enzyme source, and 15-hydroxy derivatives were produced by soya bean lipoxygenase treatment. Each monohydroxylated fatty acid was incubated with human leukocytes in the presence or absence of the calcium ionophore A23187, and dihydroxylated products were analysed by h.p.l.c. 12-Hydroxy derivatives of 20:4 omega-6, 20:5 omega-3 and 20:3 omega-9 were similarly oxygenated by both the 5-lipoxygenase and the omega-hydroxylase. As expected, the 12-hydroxy derivative of 20:3 omega-6 was not a substrate for 5-lipoxygenase, but surprisingly, omega-6 oxygenated products, like 15-OH-20:4 or HHT, were not converted by the enzyme, although being potential substrates because of the presence of two double bonds at C-5 and C-8. omega-6 oxygenated derivatives were also poorly converted by leukotriene B4 omega-hydroxylase, a cytochrome P-450-dependent enzyme. It is concluded that both leukocyte 5-lipoxygenase and omega-hydroxylase exhibit a substrate specificity towards monohydroxylated fatty acids with respect to their double bonds and/or the carbon position of the alcohol function.

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