scholarly journals Splenic abscess after arterial embolization: a rare cause of acute abdomen

2020 ◽  
Vol 2020 (6) ◽  
Author(s):  
Miguel A Moyon C ◽  
Gabriel A Molina ◽  
S Alexandra Valencia ◽  
Veronica M Basantes ◽  
R Alejandro Mecias ◽  
...  
Keyword(s):  
Rare Disease ◽  
Percutaneous Drainage ◽  
Splenic Abscess ◽  
Arterial Embolization ◽  
Medical Team ◽  
Aggressive Treatment ◽  
Diagnostic Challenge ◽  
Clinical Awareness ◽  
High Degree ◽  
Prompt Diagnosis

Abstract Splenic abscess is a rare disease and a diagnostic challenge for the medical team. Attributable to its high mortality, prompt diagnosis and treatment are essential. A high degree of clinical awareness is required in conjunction with aggressive treatment, as misleading symptoms may delay treatment and worsen the patient’s prognosis. The management of splenic abscess is based on medical therapy, antibiotics and splenectomy or percutaneous drainage. We present the case of a 58-year-old patient presented with a splenic abscess after arterial embolization. He underwent surgery and completely recovered.

Percutaneous Drainage of Splenic Abscess: Case Report and Review of Literature

PEDIATRICS ◽  
1987 ◽  
Vol 79 (6) ◽  
pp. 1029-1031
Author(s):  
MANNACHANALLUR R. RAMAKRISHNAN ◽  
T. K. PARTHA SARATHY ◽  
MANI BALU
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Percutaneous Drainage ◽  
Preoperative Diagnosis ◽  
Splenic Abscess ◽  
Pediatric Age ◽  
Review Of Literature ◽  
Autopsy Series ◽  
Clinical Awareness ◽  
High Degree

Splenic abscess is an uncommon entity, reported in 0.14% to 0.70% of several autopsy series. Untreated, the mortality approaches 100%.1 When the diagnosis is made preopenatively and treated by antibiotics and splenectomy, there is a 17% mortality, but preoperative diagnosis was made only in 33% of the cases in one review.2 High degree of clinical awareness and aggressive diagnostic approach are essential for early diagnosis. percutaneous drainage of splenic abscess has been demonstrated to be a safe and effective method of treatment in adults in eight cases,3-5 without mortality or significant complications. We present the first pediatric age patient who was successfully treated by percutaneous drainage.

scholarly journals A Case of Celiac Disease Presenting with Recurrent Attacks of Quadriparesis

2017 ◽  
Vol 25 (2) ◽  
pp. 138-141
Author(s):  
Mohammad Zaid Hossain ◽  
Pratyay Hasan ◽  
Kainat Ferdous ◽  
Kazi Tuba E Mozazfia ◽  
Md Murad Hossain ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Rare Disease ◽  
Electrolyte Imbalance ◽  
Motor Weakness ◽  
Medical College ◽  
Malabsorption Syndromes ◽  
Bangladeshi Population ◽  
Atypical Presentations ◽  
High Degree ◽  
Prompt Diagnosis

Celiac disease, once considered a rare disease in Bangladeshi population, have recently been reported more frequently. Recognition of celiac disease is not easy and a high degree of suspicion in required. Although the disease presents usually with malabsorption syndromes, atypical presentations also may occur which may cause confusion in making a prompt diagnosis. We intend to report a case who presented primarily with flaccid type of quadriparesis who ultimately was proven to be a case of celiac disease. Although neurological symptoms have been associated with celiac disease, motor weakness is very uncommon. We have proposed that in our case electrolyte imbalance have caused or contributed in causing this motor weakness.J Dhaka Medical College, Vol. 25, No.2, October, 2016, Page 138-141

scholarly journals The Challenge of Diagnosing Constitutional Mismatch Repair Deficiency Syndrome in Brain Malignancies from Young Individuals

2021 ◽  
Vol 22 (9) ◽  
pp. 4629
Author(s):  
Cristina Carrato ◽  
Carolina Sanz ◽  
Ana María Muñoz-Mármol ◽  
Ignacio Blanco ◽  
Marta Pineda ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Mismatch Repair ◽  
Rare Event ◽  
Deficiency Syndrome ◽  
Mismatch Repair Deficiency ◽  
Malignant Brain Tumors ◽  
Repair Deficiency ◽  
Clinical Awareness ◽  
High Degree ◽  
Constitutional Mismatch Repair Deficiency

Biallelic germline mismatch repair (MMR) gene (MLH1, MSH2, MSH6, and PMS2) mutations are an extremely rare event that causes constitutional mismatch repair deficiency (CMMRD) syndrome. CMMRD is underdiagnosed and often debuts with pediatric malignant brain tumors. A high degree of clinical awareness of the CMMRD phenotype is needed to identify new cases. Immunohistochemical (IHC) assessment of MMR protein expression and analysis of microsatellite instability (MSI) are the first tools with which to initiate the study of this syndrome in solid malignancies. MMR IHC shows a hallmark pattern with absence of staining in both neoplastic and non-neoplastic cells for the biallelic mutated gene. However, MSI often fails in brain malignancies. The aim of this report is to draw attention to the peculiar IHC profile that characterizes CMMRD syndrome and to review the difficulties in reaching an accurate diagnosis by describing the case of two siblings with biallelic MSH6 germline mutations and brain tumors. Given the difficulties involved in early diagnosis of CMMRD we propose the use of the IHC of MMR proteins in all malignant brain tumors diagnosed in individuals younger than 25 years-old to facilitate the diagnosis of CMMRD and to select those neoplasms that will benefit from immunotherapy treatment.

scholarly journals Renal Leiomyosarcoma: A Diagnostic Challenge

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Jose R. Valery ◽  
Winston Tan ◽  
Cherise Cortese
Keyword(s):  
Renal Mass ◽  
Early Stage ◽  
Flank Pain ◽  
Bone Lesions ◽  
Brush Cytology ◽  
Diagnostic Challenge ◽  
Male Smoker ◽  
Initial Biopsy ◽  
Pathologic Analysis ◽  
Prompt Diagnosis

Renal leiomyosarcoma is a very rare tumor that clinically and radiographically mimics more common renal malignancies. The infrequency of the condition makes it very difficult to diagnose. A 70-year-old male smoker presented with months of hematuria, right-sided flank pain, and weight loss. Imaging revealed a 3.8-centimeter renal mass that had characteristics similar to renal cell carcinoma. Initial biopsy of the mass was negative for malignancy. Two months later, subsequent imaging revealed what appeared to be metastatic bone lesions. Again, a biopsy of one of the lesions was negative for malignancy. Subsequent ureteral pyeloscopy, ureteroscopic renal pelvis biopsy, and brush cytology were negative for malignancy as well. The decision was made to perform nephrectomy for the removal of the mass. Pathologic analysis revealed renal leiomyosarcoma. This case illustrates the difficulty in diagnosing renal leiomyosarcoma. Repeated pathologic sampling was negative because of the tumor heterogeneity. Prompt diagnosis and treatment are very significant as surgical resection at an early stage offers the best prognosis.

scholarly journals Changes in the oral cavity caused by scurvy

2003 ◽  
Vol 60 (6) ◽  
pp. 753-756 ◽  
Author(s):  
Dragana Dakovic ◽  
Besir Ljuskovic ◽  
Ivan Mileusnic ◽  
Vesna Tepsic
Keyword(s):  
Vitamin C ◽  
Oral Cavity ◽  
Rare Disease ◽  
Clinical Examination ◽  
Psychiatric Patient ◽  
Clinical Signs ◽  
Complete Recovery ◽  
Vitamin C Deficiency ◽  
Plaque Control ◽  
Prompt Diagnosis

This report presents a case of a psychiatric patient with scurvy. Upon the clinical examination of the oral cavity, dry and pale lips were noted. Gingiva was highly edematous, soft, purple blue with ulcerated margins. Bleeding was noted upon slightest provocation. Teeth were also affected by the vitamin C deficiency with multiple caries. The patient was asthenic and adynamic. Petechial bleeding and hematomas were present on the skin of extremities. Therapy consisted of rehydration and vitamin C compensation - 2 g daily i.v. during 10 days period, and 1.5 g daily orally during the following 2 months. The patient maintained only partial plaque control, and complete recovery of the oral cavity was not established because the patient didn?t comply. Concerning that scurvy is a rare disease nowadays, it is very important to recognize its clinical signs, and to establish a valid and prompt diagnosis, because, when untreated, scurvy can have severe consequences on the entire organism.

scholarly journals Management of Splenic Abscess after Splenic Arterial Embolization in Severe Acute Pancreatitis: A 5-Year Single-Center Experience

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Gang Li ◽  
Lin Gao ◽  
Jing Zhou ◽  
Bo Ye ◽  
Jingzhu Zhang ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Minimally Invasive ◽  
Severe Acute Pancreatitis ◽  
Splenic Artery ◽  
Pancreatic Necrosis ◽  
Splenic Abscess ◽  
Arterial Embolization ◽  
Massive Bleeding ◽  
Massive Hemorrhage ◽  
Single Center Experience

Objective. To describe the management and prognosis of splenic abscess after splenic arterial embolization in severe acute pancreatitis (SAP) patients.Methods. This is a retrospective observational study. From August 2012 to August 2017, SAP patients with infected pancreatic necrosis (IPN) who underwent splenic arterial embolization after massive hemorrhage of the splenic artery were screened and those who developed splenic abscess were included for analysis. The demographic characteristics, etiology, treatment of splenic abscess, and clinical outcomes of these cases were collected and analyzed.Results. A total of 18 patients with splenic abscess formed after splenic arterial embolization were included for data analysis. The median age of the 18 patients was 46 years. The etiologies included biliary AP, hypertriglyceridemic AP (HTG-AP), and other causes. Ten patients underwent minimally invasive percutaneous drainage only for splenic abscess while the other eight patients received splenectomy. One patient died due to uncontrolled infection and another patient died due to massive bleeding, and the remaining sixteen patients survived.Conclusion. The incidence of splenic abscess was high in patients requiring splenic arterial embolization due to massive bleeding. Our data showed that most splenic abscess could be successfully managed with minimally invasive interventions, and traditional splenectomy should serve as a backup treatment.

scholarly journals Postoperative hemorrhage from racemose hemangioma of the bronchial artery after esophageal cancer surgery

2017 ◽  
Author(s):  
Katsushi Takebayashi ◽  
Yasuhiro Tsubosa ◽  
Satoru Matsuda ◽  
Keisuke Kawamorita ◽  
Masahiro Niihara ◽  
...  
Keyword(s):  
Rare Disease ◽  
Bronchial Artery ◽  
Arterial Embolization ◽  
Postoperative Hemorrhage ◽  
Bronchial Artery Embolization ◽  
Artery Embolization ◽  
Endoscopic Screening ◽  
Cervical Incision ◽  
The Right ◽  
Racemose Hemangioma

Abstract Introduction: Racemose hemangioma of the bronchial artery is a rare disease. The diagnosis of racemose hemangioma is difficult when affected patients are asymptomatic, and causes unexplained hemoptysis. Selective bronchial artery embolization has become the first-line treatment for this rare disease. However, feasibility and safety of bronchial artery embolization was not reported in the case with permanent tracheostomy. Case presentation: A 44-year-old woman underwent endoscopic screening during which a circular tumor was detected in the cervical esophagus, which was confirmed as squamous cell carcinoma on biopsy. She underwent cervical esophagectomy with pharyngolaryngectomy through a cervical incision. Reconstruction was performed by free jejunal transfer and permanent tracheostomy. Six weeks after surgery, hemoptysis from permanent tracheostomy was observed. Computed tomography (CT) scan revealed no bleeding around the tracheostomy, and bronchoscopy could not identify the origin of the bleeding due to a large amount of blood clots obscuring the visual field. Bronchial arteriography showed a bent, meandering and dilated bronchial artery, extending to the right bronchus with vascular hyperplasia. We diagnosed primary racemose hemangioma of the bronchial artery, which was successfully treated by transcatheter arterial embolization of the bronchial artery. After embolization, bronchoscopy revealed no bleeding. Conclusion: Findings from this case suggest that bronchial angiography is essential for diagnosis of this disease, and selective bronchial artery embolization appears to be effective in treating this disease in patients with permanent tracheostomy. Accumulation of similar cases will help to elucidate the optimal diagnosis and treatment strategy for this condition.

scholarly journals Pott's Spine with Bilateral Psoas Abscesses

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Sanjeevani Masavkar ◽  
Preeti Shanbag ◽  
Prithi Inamdar
Keyword(s):  
Lumbar Spine ◽  
Conservative Treatment ◽  
Early Diagnosis ◽  
Percutaneous Drainage ◽  
Imaging Studies ◽  
Antituberculous Treatment ◽  
Pott’S Disease ◽  
High Degree

A high degree of suspicion and appropriate imaging studies are required for the early diagnosis of Pott’s spine. We describe a 4-year-old boy with Pott’s disease of the lumbar spine with bilateral psoas abscesses. The child responded to conservative treatment with antituberculous treatment and ultrasonographically guided percutaneous drainage of the abscesses.

scholarly journals LethalClostridium difficileColitis Associated with Paclitaxel and Carboplatin Chemotherapy in Ovarian Carcinoma: Case Report and Review of the Literature

2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
V. Masciullo ◽  
S. Mainenti ◽  
D. Lorusso ◽  
P. A. Margariti ◽  
G. Scambia
Keyword(s):  
Antibiotic Use ◽  
Aggressive Treatment ◽  
Review Of The Literature ◽  
Serous Adenocarcinoma ◽  
Coffee Ground ◽  
Adenocarcinoma Of The Ovary ◽  
Life Threatening ◽  
Clostridium Difficile Colitis ◽  
Prompt Diagnosis ◽  
Prior Antibiotic Therapy

Clostridium difficile colitis, although rare, could represent a serious complication following chemotherapy. Prior antibiotic use has been considered the single most important risk factor in the development ofC. difficileinfection. Recently, the association between antineoplastic therapy andC. difficile-associated diarrhea in the absence of a prior antibiotic therapy has become more apparent. A 75-year-old woman with serous adenocarcinoma of the ovary developed lethal pancolitis caused byC. difficileafter five cycles of paclitaxel- and carboplatin-based chemotherapy. She presented with diarrhea, coffee-ground emesis, and oliguria and was hospitalized immediately for aggressive treatment. Despite all the medical efforts, her condition worsened and she died after twenty days. We describe the second case reported of a patient developing a severeC. difficilecolitis following chemotherapy without any recent antibiotic use and review the data of the literature, emphasizing the need to a prompt diagnosis and management that can significantly decrease the morbidity and life-threatening complications associated with this infection.

Management of splenic abscess in children by percutaneous drainage

2006 ◽  
Vol 41 (1) ◽  
pp. e53-e56 ◽  
Author(s):  
Roy Choudhury S. ◽  
Chadha Rajiv ◽  
Sonker Pitamber ◽  
Sharma Akshay ◽  
Singh Dharmendra
Keyword(s):  
Percutaneous Drainage ◽  
Splenic Abscess
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