scholarly journals A Case of Celiac Disease Presenting with Recurrent Attacks of Quadriparesis

2017 ◽  
Vol 25 (2) ◽  
pp. 138-141
Author(s):  
Mohammad Zaid Hossain ◽  
Pratyay Hasan ◽  
Kainat Ferdous ◽  
Kazi Tuba E Mozazfia ◽  
Md Murad Hossain ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Rare Disease ◽  
Electrolyte Imbalance ◽  
Motor Weakness ◽  
Medical College ◽  
Malabsorption Syndromes ◽  
Bangladeshi Population ◽  
Atypical Presentations ◽  
High Degree ◽  
Prompt Diagnosis

Celiac disease, once considered a rare disease in Bangladeshi population, have recently been reported more frequently. Recognition of celiac disease is not easy and a high degree of suspicion in required. Although the disease presents usually with malabsorption syndromes, atypical presentations also may occur which may cause confusion in making a prompt diagnosis. We intend to report a case who presented primarily with flaccid type of quadriparesis who ultimately was proven to be a case of celiac disease. Although neurological symptoms have been associated with celiac disease, motor weakness is very uncommon. We have proposed that in our case electrolyte imbalance have caused or contributed in causing this motor weakness.J Dhaka Medical College, Vol. 25, No.2, October, 2016, Page 138-141

scholarly journals Splenic abscess after arterial embolization: a rare cause of acute abdomen

2020 ◽  
Vol 2020 (6) ◽  
Author(s):  
Miguel A Moyon C ◽  
Gabriel A Molina ◽  
S Alexandra Valencia ◽  
Veronica M Basantes ◽  
R Alejandro Mecias ◽  
...  
Keyword(s):  
Rare Disease ◽  
Percutaneous Drainage ◽  
Splenic Abscess ◽  
Arterial Embolization ◽  
Medical Team ◽  
Aggressive Treatment ◽  
Diagnostic Challenge ◽  
Clinical Awareness ◽  
High Degree ◽  
Prompt Diagnosis

Abstract Splenic abscess is a rare disease and a diagnostic challenge for the medical team. Attributable to its high mortality, prompt diagnosis and treatment are essential. A high degree of clinical awareness is required in conjunction with aggressive treatment, as misleading symptoms may delay treatment and worsen the patient’s prognosis. The management of splenic abscess is based on medical therapy, antibiotics and splenectomy or percutaneous drainage. We present the case of a 58-year-old patient presented with a splenic abscess after arterial embolization. He underwent surgery and completely recovered.

scholarly journals Hubert Maitland Turnbull, 1875-1955

1957 ◽  
Vol 3 ◽  
pp. 289-304 ◽  
Keyword(s):  
Original Work ◽  
Medical Schools ◽  
Medical College ◽  
Hospital Medical ◽  
London Hospital ◽  
The Subject ◽  
Morbid Anatomy ◽  
High Degree ◽  
Attention To Detail

Hubert Maitland Turnbull, who died on 29 September 1955 some eight years after retirement from the Chair of Morbid Anatomy at the London Hospital Medical College, occupied a position of eminence in British pathology. Not only was he greatly esteemed by his colleagues at the London but his influence extended widely throughout the medical schools of this and other countries of the Commonwealth. This was due not so much to his ability as an initiator and director of research, even though he was responsible for a considerable amount of valuable original work during his forty years at the London Hospital, but to a particular genius for accuracy of observation and meticulous attention to detail which he possessed in high degree and applied with almost religious fervour to everything that he did. Entering pathology at a time when many in this country held that morbid anatomy was a dead subject, Virchow, in their opinion, having left little new territory to be explored, Turnbull set himself to revolutionize morbid anatomical practice and to raise the subject to the level of a science. And so well did he succeed that he proved a source of inspiration not only to his fellow pathologists and those young graduates who chose to emulate him, but also to the much wider circle of clinicians who sought the privilege of working for a time in his department as a prelude to specialization in some other branch of medicine.

scholarly journals Cerebral malaria in children : an update

2015 ◽  
Vol 6 (2) ◽  
pp. 45-47
Author(s):  
Mirza Md Ziaul Islam ◽  
M Mizanur Rahman
Keyword(s):  
Cerebral Malaria ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Medical Emergency ◽  
Care Hospital ◽  
Medical College ◽  
Antimalarial Therapy ◽  
Neurological Presentation ◽  
Supportive Management ◽  
Prompt Diagnosis

Cerebral malaria (CM) is the most severe neurological presentation of acute falciparum malaria. It is a medical emergency, the hallmark of which is the presence of coma probably due to diffuse encephalopathy. A compromised microcirculation with sequestration of parasitized erythrocytes is central to the pathogenesis of cerebral malaria. The death is unacceptably high even with effective antimalarials in tertiary care hospital. The mainstay of treatment of cerebral malaria include prompt diagnosis and early institution of effective antimalarial therapy, recognition of complications, and appropriate supportive management in an ICU. Neurological sequlae are increasingly recognized, but further research on the pathogenesis of coma and neurological damage is required to develop other ancillary treatmentsNorthern International Medical College Journal Vol.6(2) 2015: 45-47

scholarly journals Changes in the oral cavity caused by scurvy

2003 ◽  
Vol 60 (6) ◽  
pp. 753-756 ◽  
Author(s):  
Dragana Dakovic ◽  
Besir Ljuskovic ◽  
Ivan Mileusnic ◽  
Vesna Tepsic
Keyword(s):  
Vitamin C ◽  
Oral Cavity ◽  
Rare Disease ◽  
Clinical Examination ◽  
Psychiatric Patient ◽  
Clinical Signs ◽  
Complete Recovery ◽  
Vitamin C Deficiency ◽  
Plaque Control ◽  
Prompt Diagnosis

This report presents a case of a psychiatric patient with scurvy. Upon the clinical examination of the oral cavity, dry and pale lips were noted. Gingiva was highly edematous, soft, purple blue with ulcerated margins. Bleeding was noted upon slightest provocation. Teeth were also affected by the vitamin C deficiency with multiple caries. The patient was asthenic and adynamic. Petechial bleeding and hematomas were present on the skin of extremities. Therapy consisted of rehydration and vitamin C compensation - 2 g daily i.v. during 10 days period, and 1.5 g daily orally during the following 2 months. The patient maintained only partial plaque control, and complete recovery of the oral cavity was not established because the patient didn?t comply. Concerning that scurvy is a rare disease nowadays, it is very important to recognize its clinical signs, and to establish a valid and prompt diagnosis, because, when untreated, scurvy can have severe consequences on the entire organism.

scholarly journals Salmonella Hepatitis in Children : An Update

2020 ◽  
Vol 10 (2) ◽  
pp. 397-399
Author(s):  
Sadika Kadir ◽  
Tamanna Begum ◽  
Md Rafiqul Islam ◽  
Golam Nabi ◽  
Md Ashraful Haque ◽  
...  
Keyword(s):  
Typhoid Fever ◽  
Enteric Fever ◽  
Clinical Course ◽  
Clinical Importance ◽  
Positive Culture ◽  
Reticuloendothelial System ◽  
Bleeding Diathesis ◽  
Medical College ◽  
Time Index ◽  
Atypical Presentations

Salmonella hepatitis is one of the atypical presentations of typhoid fever and can be defined as reversible involvement of liver during the course of typhoid fever. There have been more than 150 cases of salmonella hepatitis reported both in developed and developing countries. The documented incidence varies widely from 1 to 26% of patients with Typhoid fever. It presents with jaundice and tender hepatosplenomegaly. Investigation shows slightly raised transaminase levels with or without 5 adenosine neucleosidase and or decreased prothombin time index. It complicates into hepatic encephalopathy and bleeding diathesis. A positive culture for Salmonella from blood or stool is essential to differentiate Salmonella hepatitis from other causes of acute hepatitis. Hepatic pathology is characterized by the presence of typhoid nodules with marked hyperplasia of reticuloendothelial system. The ALT/LDH ratio < 9 is suggestive of Salmonella hepatitis which is > 9 in viral hepatitis. The prognosis is usually good as Salmonella hepatitis responses with specific antibiotic therapy and jaundice resolves with clinical improvement. The clinical course can be severe with high mortality (20%) sometime. In our country where enteric fever is endemic, the recognition of Salmonella hepatitis is of clinical importance . Northern International Medical College Journal Vol.10 (2) Jan 2019: 397-399

scholarly journals Histomorphometric Study of the Glomeruli of the Kidney in Bangladeshi Population

2015 ◽  
Vol 9 (1) ◽  
pp. 11-16
Author(s):  
Fatema Johora ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Sunjida Shahriah ◽  
Rukshana Ahmed ◽  
Shamim Ara
Keyword(s):  
Left Kidney ◽  
Age Groups ◽  
Population Based ◽  
Cross Sectional ◽  
Medical College ◽  
Histomorphometric Study ◽  
The Mean ◽  
Group 10 ◽  
Bangladeshi Population ◽  
The Right

Background: Controversies still prevail on glomerular changes of kidney whether due to normal aging or its association with diseases Objective: The aim of the present study was to see the variation in number and size of the glomeruli of kidney with increasing age in a Bangladeshi population based on autopsy. Methods: This cross-sectional, descriptive study was done in the Department of Anatomy, Dhaka Medical College, Dhaka, from July 2008 to June 2009, based on collection of 140 post mortem human kidneys collected from 70 unclaimed dead bodies from the morgue. All the samples were divided into three age-groups: 10-19 years, 20-39 years and 40-59 years. Histological slides were prepared by using routine Harris’ Haematoxylin and Eosin (H & E) stain. The number of glomeruli was measured by point counting technique, while the size (diameter) was measured by using ocular and stage micrometer. Results: The mean ± SE number of glomeruli per sq. mm found in the right and left kidney were 8.45±0.52 and 8.67±0.80 in group 10-19 years, 9.90±0.42 and 9.92±0.47 in 20-39 years, and 8.52±0.18 and 8.55±0.16 in 40-59 years respectively. Besides, the size (mean ± SE diameter) of glomeruli was found in the right and left kidney were 43.96±3.01ìm and 143.92±2.90ìm in group 10-19 years, 153.69±5.18ìm and 153.61±5.24ìm in 20-39 years, and 140.48±0.95ìm and 140.78±0.88ìm in 40-59 years respectively. Conclusion: No difference was found in number and size of glomeruli between right and left kidney in any group. Similarly, no difference was also evident among different age groups. DOI: http://dx.doi.org/10.3329/jbsp.v9i1.22788 Bangladesh Soc Physiol. 2014, June; 9(1): 11-16

scholarly journals Case Report on a Rare Disease in Lithuania: Congenital Chloride Diarrhea

2018 ◽  
Vol 08 (01) ◽  
pp. 024-026 ◽  
Author(s):  
Olga Liaugaudiene ◽  
Dalia Stoniene ◽  
Ruta Kucinskiene ◽  
Christophe Buffat ◽  
Virginija Asmoniene
Keyword(s):  
Rare Disease ◽  
Molecular Genetic ◽  
Electrolyte Imbalance ◽  
Secretory Diarrhea ◽  
Watery Diarrhea ◽  
Founder Mutations ◽  
Adequate Treatment ◽  
Surgical Interventions ◽  
Congenital Chloride Diarrhea ◽  
Long Term Prognosis

AbstractCongenital chloride diarrhea (CCD) is a rare disease, manifesting with secretory diarrhea and life-threatening electrolyte imbalance during infancy. The early diagnosis of CCD is therefore necessary for the adequate treatment. The long-term prognosis of properly managed CCD is favorable. We present a case of complicated CCD with necrotizing enterocolitis. The child was born to nonconsanguineous parents of Lithuanian origin. CCD was suspected due to watery diarrhea, progressive hypochloremia, and high fecal chlorides. Despite oral electrolytes being prescribed, volvulus of small intestine developed requiring several surgical interventions. The clinical diagnosis of CCD was confirmed by molecular genetic testing of SLC26A3, which revealed two Polish founder mutations in the DNA of the patient. The prevalence of CCD in Lithuanian neighbor Poland is approximately 1 in 200,000 live births. This is the first described case of CCD in Lithuania to our knowledge, leading to the suggestion that this disease may be underdiagnosed.

scholarly journals Acute neuromuscular weakness associated with dengue infection

2012 ◽  
Vol 03 (01) ◽  
pp. 36-39 ◽  
Author(s):  
Harmanjit Singh Hira ◽  
Amandeep Kaur ◽  
Anuj Shukla
Keyword(s):  
Dengue Virus ◽  
Dengue Infection ◽  
Neurological Complications ◽  
Electrolyte Imbalance ◽  
Guillain Barre Syndrome ◽  
Motor Weakness ◽  
Presenting Symptoms ◽  
Guillain Barré Syndrome ◽  
Serotype 1 ◽  
Guillain Barré

ABSTRACT Background: Dengue infections may present with neurological complications. Whether these are due to neuromuscular disease or electrolyte imbalance is unclear. Materials and Methods: Eighty-eight patients of dengue fever required hospitalization during epidemic in year 2010. Twelve of them presented with acute neuromuscular weakness. We enrolled them for study. Diagnosis of dengue infection based on clinical profile of patients, positive serum IgM ELISA, NS1 antigen, and sero-typing. Complete hemogram, kidney and liver functions, serum electrolytes, and creatine phosphokinase (CPK) were tested. In addition, two patients underwent nerve conduction velocity (NCV) test and electromyography. Results: Twelve patients were included in the present study. Their age was between 18 and 34 years. Fever, myalgia, and motor weakness of limbs were most common presenting symptoms. Motor weakness developed on 2 nd to 4 th day of illness in 11 of 12 patients. In one patient, it developed on 10 th day of illness. Ten of 12 showed hypokalemia. One was of Guillain-Barré syndrome and other suffered from myositis; they underwent NCV and electromyography. Serum CPK and SGOT raised in 8 out of 12 patients. CPK of patient of myositis was 5098 IU. All of 12 patients had thrombocytopenia. WBC was in normal range. Dengue virus was isolated in three patients, and it was of serotype 1. CSF was normal in all. Within 24 hours, those with hypokalemia recovered by potassium correction. Conclusions: It was concluded that the dengue virus infection led to acute neuromuscular weakness because of hypokalemia, myositis, and Guillain-Barré syndrome. It was suggested to look for presence of hypokalemia in such patients.

Celiac disease—not a rare disease after all!

2004 ◽  
Vol 144 (5) ◽  
pp. A1
Author(s):  
William F Balistreri
Keyword(s):  
Celiac Disease ◽  
Rare Disease
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