The Role of Aromatherapy in the Treatment of Substance Use and Co-Occurring Disorders

Author(s):  
Cathy Skipper ◽  
Florian Birkmayer

Aromatherapy can be an important tool in the treatment of substance abuse and co-occurring disorders. When used by trained specialists, essential oils are safe, simple, and effective both in alleviating symptoms as well as helping increase self-awareness and transform consciousness. Olfaction is a powerful sensory modality, and olfactory receptors have been found in nearly every tissue of the body and parts of the Central Nervous System (CNS) relevant to addiction and motivation. Essential oils are widely used to support and alleviate nervous symptom disorders such as those triggered by addiction (i.e., anxiety, sleep problems, panic attacks, depression, stress etc.). The available scientific literature supports the traditional uses of the most common essential oils in this domain and is encouraging for the continued development of these powerful plants extracts for addiction support.

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Alessandra Berry ◽  
Erika Bindocci ◽  
Enrico Alleva

Nerve Growth Factor (NGF) was initially studied for its role as a key player in the regulation of peripheral innervations. However, the successive finding of its release in the bloodstream of male mice following aggressive encounters and its presence in the central nervous system led to the hypothesis that variations in brain NGF levels, caused by psychosocial stressor, and the related alterations in emotionality, could be functional to the development of proper strategies to cope with the stressor itself and thus to survive. Years later this vision is still relevant, and the body of evidence on the role of NGF has been strengthened and expanded from trophic factor playing a role in brain growth and differentiation to a much more complex messenger, involved in psychoneuroendocrine plasticity.


2019 ◽  
Author(s):  
Johanna Bischof ◽  
Margot E. Day ◽  
Kelsie A. Miller ◽  
Joshua LaPalme ◽  
Michael Levin

AbstractThe coordination of tissue-level polarity with organism-level polarity is crucial in development, disease, and regeneration. Exploiting the flexibility of the body plan in regenerating planarians, we used mirror duplication of the primary axis to show how established tissue-level polarity adapts to new organism-level polarity. Tracking of cilia-driven flow to characterize planar cell polarity of the epithelium revealed a remarkable reorientation of tissue polarity in double-headed planarians. This reorientation is driven by signals produced by the intact brain and is not hampered by radiation-induced removal of stem cells. The nervous system itself adapts its polarity to match the new organismal anatomy in these animals as revealed by distinct regenerative outcomes driven by polarized nerve transport. Thus, signals from the central nervous system can dynamically control and re-orient tissue-level polarity to match the organism-level anatomical configuration, illustrating a novel role of the nervous system in the regulation of patterning.


2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Cividini A ◽  

At the beginning of 2020, Covid-19 pandemic has deeply and quickly changed healthcare transforming our hospitals and challenging health professionals both as clinicians and humans. We found ourselves fighting an invisible, unknown enemy, facing an unpredictable disease and had no choice but adapting and reacting to an overgrowing emergency situation. Whole hospitals were dedicated to Covid-19 patients and many specialized physicians had to quickly learn about treating Sars-Cov-2 infection. Over the last year better knowledge of pathophysiology and treatment as well as the establishment of redesigned organizational models have contributed to reduce the role of chance, fear and unexpected, but as the pandemic keeps unfolding, healthcare workers are still under pressure. As a result, they are exposed to a high risk of post-traumatic stress disorder as well as burn-out syndrome. As a neurosurgeon working in a Covid-converted hospital and an hypnologist I realized it was my duty to use my skills to help colleagues in need. I started offering hypnosis sessions to help colleagues to stay in-balance and react to this situation in a resilient way. In this letter I underline some features which I find to be peculiar to the Covid-19 pandemic (some of them more relevant to the first waves), describe their consequences on health professionals’ life and suggest the potential role of hypnosis as a tool to promote mental health. • Loss of anchors: entire hospitals or wards have been turned into Covid-dedicated areas, thus requiring professionals to change their daily habits, to quickly learn new skills and to be exposed to a constantly changing situation. The sudden and continuous loss of such anchors is deeply destabilizing. • Change in social engagement: self-quarantine, limiting of social activities, avoidance of close contacts and having to wear disposable equipment partially covering the face impact on the usual way of being socially involved. Paradoxically, family and community can’t offer a safe shelter in a moment of major need. • Identification: before vaccines became available, the high number of health professionals affected by the disease, the unfortunately common unavailability of proper personal protective equipment and the need for a constant monitoring of self health status, often lead to identification with patients or victims. • Lack of control: such a level of uncertainty and lack of knowledge is new to many young doctors who have been raised studying diagnosis and treatment of mostly well-defined and known conditions. • Social media impact: being connected inevitably exposes users to a constant flow of bad or fake news. Besides being a reason to recall a healthier digital lifestyle, this leads to rumination and prevents people from using spare time to fully recover from the fatigue. Carers who asked for hypnosis sessions mainly complained about sleep-related problems, panic attacks, rumination, anxiety and fear (of dying alone, of not being able to make plans for the future, of not being able to reconnect with loved ones, of transmitting the disease to family members or colleagues, of not being able to breathe). The reiteration of such symptoms puts health professionals on the dangerous road to burn-out and eventually PTSD. Hypnosis, as well as all disciplines aimed at improving mental health (mind-body techniques, mindfulness, meditation, yoga, deep relaxation..) may offer help in preventing them. Healthcarers who required hypnosis sessions were invited to join after or before their shift. I treated clinicians and nurses, aged 25-55 yo, mainly female. A short introductory talk was aimed at identifying their perception of the situation and potential topics to work on during the session. Being all the patients highly motivated in feeling better, almost none had difficulties in trance-induction. Sessions had a mean duration of 45-60’ and were held in the hospital facilities. I found the following techniques being particularly useful: • Focus on breathing: being Covid-19 disease mainly a respiratory illness and due to the need to work wearing uncomfortable masks, focus on breathing is crucial. Reconnecting people to their natural breath may help in keeping a healthy connection to the body and preventing panic attacks. • Safe place: visualizing and then anchoring a “safe place” help subjects to realize that they can actively choose to feel better going back to their safe place every time they need it. • Metaphors: the use of subject-tailored metaphors is particularly effective, giving immediate relief as well as working on a longer-lasting deeper level. • Temporal dissociation and retrieving happy memories: in difficult and uncertain times, reestablishing a connection with happy memories and with past achievements helps subjects to discover their own value, be self-confident and get rid of harmful helplessness feeling. • Future reorienting: for all the aforementioned reasons future reorienting techniques may be useful for those people feeling afraid of not being able to look beyond this challenging times All subjects were satisfied with the session, found it helpful and most of them asked to repeat the treatment. I hope this letter may contribute to increase institutions’ awareness on the need for measures aimed at maintaining and supporting mental health of all professionals involved in fighting the ongoing pandemic. Besides, it’s also addressed to professionals as a reminder to promptly identify stress-related red flags and ask for help. Hypnosis is a powerful, effective and safe tool.


2018 ◽  
Vol 25 (4) ◽  
pp. 334-343 ◽  
Author(s):  
Lauren Rosko ◽  
Victoria N. Smith ◽  
Reiji Yamazaki ◽  
Jeffrey K. Huang

The human brain weighs approximately 2% of the body; however, it consumes about 20% of a person’s total energy intake. Cellular bioenergetics in the central nervous system involves a delicate balance between biochemical processes engaged in energy conversion and those responsible for respiration. Neurons have high energy demands, which rely on metabolic coupling with glia, such as with oligodendrocytes and astrocytes. It has been well established that astrocytes recycle and transport glutamine to neurons to make the essential neurotransmitters, glutamate and GABA, as well as shuttle lactate to support energy synthesis in neurons. However, the metabolic role of oligodendrocytes in the central nervous system is less clear. In this review, we discuss the energetic demands of oligodendrocytes in their survival and maturation, the impact of altered oligodendrocyte energetics on disease pathology, and the role of energetic metabolites, taurine, creatine, N-acetylaspartate, and biotin, in regulating oligodendrocyte function.


The significance of mitochondria in plant cells is a subject to which a great deal of attention has been paid in past years, and from the studies of many cytologists it has become apparent that these bodies are fundamentally concerned in the formation of many different substances in the cell. Fat droplets, anthocyanins, essential oils (28) and protein grains may all be quoted as examples of such substances (Cowdry, 5). Starch and other plastid products also appear to owe their origin indirectly to mitochondria; for it has been shown by various observers that plastids are in reality enlarged and transformed mitochondria, which take on the varying functions of the production of starch, chlorophyll, anthocyanins, fat, etc., according to whether they become amyloplasts, chloroplasts, chromoplasts, elaioplasts or other such protoplasmic structures. It seems, moreover, that these substances are originally formed within the mitochondria, which later enlarge to form the body of the plastids (Cowdry, 6). A suggested explanation of this productive activity of mitochondria is found in the eclectosome theory of Regaud (32), according to which mitochondria play the rôle of plasts, selecting materials from the cytoplasm, and fabricating them in their interior into various products. More in accord with known physicochemical processes, however, is the now generally accepted interpretation recently expressed by Cowdry (7), wherein the phase-boundary of the mitochondria and the surrounding cytoplasm is regarded as the seat of processes of elaboration, beginning with adsorption of the molecules of certain solutes, and ending with a series of chemical or physical interactions between the mitochondrial material and the incoming substances—such interactions leading to the building up of new compounds of widely different character.


2020 ◽  
Vol 18 ◽  
Author(s):  
Hai-Jian Sun ◽  
Zhi-Yuan Wu ◽  
Xiao-Wei Nie ◽  
Jin-Song Bian

: Hydrogen sulfide (H2S) and hydrogen polysulfides are recognized as important signaling molecules that are generated physiologically in the body, including the central nervous system (CNS). Studies have shown that these two molecules are involved in cytoprotection against oxidative stress and inflammatory response. In the brain system, H2S and polysulfides exert multiple functions in both health and diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington's disease (HD), memory decline, and glioma. Mechanistically, S-Persulfidation (also known as S-sulfuration or S-sulfhydration) of target proteins is believed to be a fundamental mechanism that underlies H2S-regulated signaling pathways. Cysteine S-Persulfidation is an important paradigm of post-translational protein modification in the process of H2S signaling. This model is established as a critical redox mechanism to regulate numerous biological functions, especially in H2S-mediated neuroprotection and neurogenesis. Although the current research of S-Persulfidation is still in its infancy, accumulative evidence suggests that protein S-Persulfidation may share similar characteristics with protein S-nitrosylation. In this review, we will provide a comprehensive insight into the S-Persulfidation biology of H2S and polysulfides in neurological ailments and presume potential avenues for therapeutic development in these disorders based on S-Persulfidation of target proteins.


2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Khushi Bruta ◽  
Vanshika ◽  
Kishnoor Bhasin ◽  
Bhawana

AbstractSerotonin or 5-hydroxytryptamine (5-HT)- a neurotransmitter of both the Enteric Nervous System and the Central Nervous System is synthesized by the hydroxylation of L- tryptophan to 5-hydroxytryptophan.Serotonin has been associated with gut functions like assimilation and absorption, alongside the regulation of particle transport and fluid discharge in the gastrointestinal tract and its deficiency is found to be a prominent factor in the prevalence of gut disorders like Irritable Bowel Syndrome.For this review, we assessed the conventional treatment methods of common drugs, with the recently accredited treatment options like dietary regulation, exercise, meditation, and acupuncture. Having found that the most commonly used drugs exhibited various side effects like nausea, fatigue, rash, and dizziness, an in-depth evaluation of different Indian dietary patterns and their respective effects on tryptophan levels has been highlighted to formulate an ideal diet for patients with Irritable Bowel Syndrome (IBS). This review seeks to explore the numerous studies conducted to link IBS with the lack of serotonin production in the body, alongside exploring the evidence associating certain foods with raised tryptophan levels to hypothesize a suitable Indian diet.This review, in its essence, stresses the crucial need for further research on the dietary implications of common Indian foods and their FODMAP (Fermented Oligosaccharides, Disaccharides, Monosaccharides, And Polyols) contents, while underscoring the benefits of using unconventional and natural methods for the treatment of tryptophan-related gut disorders.


2021 ◽  
Vol 11 (3) ◽  
pp. 284
Author(s):  
Grazia Fernanda Spitoni ◽  
Giorgio Pireddu ◽  
Valerio Zanellati ◽  
Beatrice Dionisi ◽  
Gaspare Galati ◽  
...  

Several studies have found in the sense of touch a good sensory modality by which to study body representation. Here, we address the “metric component of body representation”, a specific function developed to process the discrimination of tactile distances on the body. The literature suggests the involvement of the right angular gyrus (rAG) in processing the tactile metricity on the body. The question of this study is the following: is the rAG also responsible for the visual metric component of body representation? We used tDCS (anodal and sham) in 20 subjects who were administered an on-body distance discrimination task with both tactile and visual stimuli. They were also asked to perform the same task in a near-body condition. The results allow us to confirm the role of rAG in the estimation of tactile distances. Further, we also showed that rAG might be involved in the discrimination of distances on the body not only in tactile but also in visual modality. Finally, based on the significant effects of anodal stimulation even in a near-body visual discrimination task, we proposed a higher-order function of the AG in terms of a supramodal comparator of quantities.


Pharmaceutics ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1700
Author(s):  
Rafael Alves da Silva ◽  
Flávia Maria Pinto Monteiro Antonieti ◽  
Denise Von Dolinger de Brito Röder ◽  
Reginaldo dos Santos Pedroso

Candida is a common agent of infection in humans, which has a wide distribution and is a colonizer fungus of the body, occasionally assuming the role of a pathogen. The type of treatment depends on the site of infection and the clinical condition of the patient. Superficial infections, such as mucosal infections, can be treated with topical medications. So-called alternative therapies have rarely been studied, although the literature records the effectiveness of some treatments, especially as complementary therapy. The aims of this review were to analyze evidence of the anti-Candida inhibitory activity of essential oils of the Citrus, Cupressus, Litsea, and Melaleuca species; in addition to addressing the chemical composition, probable mechanisms of antifungal action and studies of toxicity, cytotoxicity, and genotoxicity were included. The literature from Medline/PubMed, Science Direct, Scopus, Web of Science, and the Brazilian database Periodic Capes was reviewed. Thirty-eight articles were selected, which included two articles on Litsea spp., seven on Cupressus spp., thirteen articles on Citrus spp., and twenty-one articles on Melaleuca spp. In conclusion, this study showed in vitro evidence for the use of essential oils of the plant species evaluated for the treatment of infections caused by different Candida species.


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