Dermatology

2016 ◽  
Keyword(s):  
Hidradenitis Suppurativa ◽  
Clinical Observation ◽  
Skin Diseases ◽  
Evidence Base ◽  
Rapid Progression ◽  
Cutaneous Infection ◽  
The Past ◽  
Skin Conditions ◽  
Skin Biology

Over the past 50 years, there have been great advances in our understanding of skin biology and the aetiopathogenesis of skin diseases, and in the development of treatments for these. Immunosuppression for use in cutaneous infection, the use of antibiotics and corticosteroids in the reduction of morbidities in skin conditions, and an increasing understanding of molecular pathways, among a range of other developments, have allowed for rapid progression in the treatment of dermatological conditions. Carefully designed studies have been vital in the development of treatment; however, clinical observation continues to have a role. The increasing number of therapeutic options for skin conditions brings with it a need for better evidence of relative efficacy, acceptability, and long-term safety. Moreover, there are still many skin conditions for which limited effective treatments are available such as vitiligo, hidradenitis suppurativa, and viral warts. This chapter highlights the evidence base for some major advances in dermatology.

Chronisch-entzündliche Hauterkrankungen und psychische Erkrankungen - Zusammenhänge beachten und daran denken

2019 ◽  
Vol 7 (1) ◽  
pp. 16-17
Author(s):  
Sandra Philipp
Keyword(s):  
Affective Disorders ◽  
Hidradenitis Suppurativa ◽  
Skin Diseases ◽  
Depression And Anxiety ◽  
Inflammatory Skin Diseases ◽  
Depressive Symptomology ◽  
The Past ◽  
Inflammatory Processes ◽  
Chronisch Entzündliche

The prevalence of affective disorders such as depression and anxiety is particularly high in patients with autoimmune diseases, including inflammatory skin diseases such as psoriasis, atopic dermatitis, and hidradenitis suppurativa. A dysregulated immune response has been linked to the precipitation of depression in many patient populations. However, studies examining the extent to which the underlying skin disease inflammatory processes contribute to depression and a subsequent decline in quality of life are limited. The published literature over the past 5 years was reviewed for evidence of a relationship between depression and inflammatory processes in the context of skin pathology. The findings, particularly the evidence from interventional clinical trials of targeted anti-cytokine therapies, suggest that proinflammatory cytokines associated with several skin diseases may be causally linked with the coexistent depressive symptomology.

Ending Homelessness?

2020 ◽  
Author(s):  
Mike Allen ◽  
Lars Benjaminsen ◽  
Eoin O'Sullivan ◽  
Nicholas Pleace
Keyword(s):  
Research Evidence ◽  
Detailed Comparison ◽  
Evidence Base ◽  
Policy Objective ◽  
The Past ◽  
What Works ◽  
Time Period ◽  
Support Mechanisms ◽  
Key Driver

In recent years, across Europe, North America and the Antipodes, a significant number of countries, states and regions have devised strategies that aim to end long-term homelessness and the need to sleep rough. Long considered an intractable or ‘wicked’ social problem, the notion that homelessness could be ended represents a significant sea change in conceptualising and responding to homelessness. A key driver for states, regions and municipalities to devise plans to end homelessness, and an optimism that this policy objective can be achieved, is that there is an increasing research evidence base on what works to end homelessness. This increasingly sophisticated research evidence covers both the prevention of homelessness in the first instance and the support mechanisms that can ensure sustainable exits and stable, secure accommodation for people who have experienced homelessness. This book explores these issues through a detailed comparison of the experiences of Denmark, Finland and Ireland over the past decade. From 2008 to the end of 2018, the numbers living rough and in temporary and emergency accommodation showed a decline of 72 per cent in Finland, while the number of households in emergency accommodation increased by 300 per cent in Ireland; in Denmark, the number of adults in emergency accommodation increased by 12 per cent over the shorter time period of 2009–17. The purpose of this book is to offer explanations for stark variations in these outcomes despite similar starting points.

scholarly journals Atypical Mycobacterial Infection Arising Amid Corticosteroid Therapy for Livedoid Vasculopathy

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
John R. Edminister ◽  
Nicole Dominiak ◽  
Lorie D. Gottwald
Keyword(s):  
Corticosteroid Therapy ◽  
Skin Diseases ◽  
Mycobacterial Infection ◽  
Definitive Treatment ◽  
Cutaneous Infection ◽  
Randomized Controlled ◽  
Atypical Mycobacterial Infection ◽  
Livedoid Vasculopathy ◽  
Skin Nodules

Patients who suffer from rare skin diseases may try numerous therapies with many potential side effects before achieving remission. Livedoid vasculopathy (LV) is one such rare disease that lacks a definitive treatment as evidenced by randomized controlled trials. Although corticosteroids help reduce the pain flares associated with LV, they come at the risk of immunosuppression. We present a case of disseminated cutaneous infection of M. chelonae/abscessus arising in a diabetic patient on long-term corticosteroid therapy. This patient required an intensive antibiotic regimen and potentially lifelong antibiotic suppression pending improvement of her disseminated cutaneous infection. We report this case to increase awareness of the diagnostic consideration of atypical, rapidly growing mycobacterial (RGM) infection when encountering patients with a diffuse onset of ulcerative skin nodules amid a background of diabetes and long-term corticosteroid use.

scholarly journals Quality of Life in Patients with Skin Disease and Their Cohabitants

2021 ◽  
Author(s):  
Trinidad Montero-Vílchez ◽  
Manuel Sánchez-Díaz ◽  
Antonio Martínez-López ◽  
Salvador Arias-Santiago
Keyword(s):  
Quality Of Life ◽  
Hidradenitis Suppurativa ◽  
Skin Diseases ◽  
Life Quality ◽  
Related Quality ◽  
Health Related ◽  
Chronic Skin ◽  
Skin Conditions ◽  
Chronic Skin Diseases

Health evaluation implies assess multidimensional aspects of a person’s development, such as physical, social, psychological, and emotional features. It is important to consider all these factors to apply a needs-oriented each patient approach. Chronic skin diseases have a great impact on quality of life, even more than other chronic conditions. For example, hidradenitis suppurativa is estimated to impair quality of life more than cardiovascular disease, lung disease or endocrine diseases. Multiple tools have been developed to measure health-related quality of life in patient, being the Dermatology Life Quality Index (DLQI) the most used. Psoriasis, hidradenitis suppurativa, acne, atopic dermatitis and hair disorders are those with the greatest impact on patients’ quality of life. Moreover, chronic skin conditions impair not only patients’ quality of life, but also cohabitants. Nevertheless, there is scarce information regarding the impact on their cohabitants. So, the objective of this chapter is to review the literature to assess the psychological and social effects of dermatological conditions both on patients and cohabitants.

Investigating Personality and Psychopathology in Patients With Psoriasis

2017 ◽  
Vol 38 (2) ◽  
pp. 87-107 ◽  
Author(s):  
Chiara Vari ◽  
Patrizia Velotti ◽  
Alessandro Crisi ◽  
Silvana Carlesimo ◽  
Antonio G. Richetta ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Clinical Importance ◽  
Self Report ◽  
Psychological Issues ◽  
Self Evaluation ◽  
Affective Quality ◽  
Millon Clinical Multiaxial Inventory ◽  
Study Results ◽  
Completion Test ◽  
Skin Conditions

Abstract. A broad range of literature reported higher rates of psychopathology and personality disorders among patients affected by skin conditions. Specifically, depression, anxiety, and suicidal ideations are more frequently reported by patients affected by skin diseases. This study aimed to examine psychopathology and personality in a group of patients affected by psoriasis by means of a self-report measure (Millon Clinical Multiaxial Inventory – MCMI-III) and a performance-based technique (Wartegg Drawing Completion Test [WDCT], CWS). Study results showed a higher rate of passive-aggressiveness and paranoia among psoriatic patients (MCMI-III). When assessing patients through the performance-based technique (WDCT, CWS), a higher rate of global rejection (GR) – linked by previous literature to suicidal ideation – and a lower affective quality of the drawings emerged. We discuss the clinical importance of detecting psychological issues in dermatology patients by means of a multimethod assessment that goes beyond patients’ self-evaluation of their symptoms and emotions.

Cosmetic Allergen in the Past and Present

2017 ◽  
Vol 2 (3) ◽  
Keyword(s):  
World War Ii ◽  
20Th Century ◽  
Normal Skin ◽  
World War ◽  
Patch Tests ◽  
The Past ◽  
Skin Conditions ◽  
Cosmetic Dermatitis ◽  
Facial Dermatitis ◽  
International Research Project

For almost 20 years after the end of World War II, many Japanese women were challenged by a dark secondary hyper pigmentation on their faces. The causation of this condition was unknown and incurable at the time. However this symptom became curable after a number of new cosmetic allergens were discovered through patch tests and as an aftermath, various cosmetics and soaps that eliminated all these allergens were put into production to be used exclusively for these patients. An international research project conducted by seven countries was set out to find out the new allergens and discover non-allergic cosmetic materials. Due to these efforts, two disastrous cosmetic primary sensitizers were banned and this helped to decrease allergic cosmetic dermatitis. Towards the end of the 20th century, the rate of positives among cosmetic sensitizers decreased to levels of 5% - 8% and have since maintained its rates into the 21th century. Currently, metal ions such as the likes of nickel have been identified as being the most common allergens found in cosmetics and cosmetic instruments. They often produce rosacea-like facial dermatitis and therefore allergen controlled soaps and cosmetics have been proved to be useful in recovering normal skin conditions.

Enabling Community Well-being Self-Monitoring in the Context of Mining: The Naskapi Nation of Kawawachikamach

2016 ◽  
Vol 1 (2) ◽  
Author(s):  
Robert Klinck ◽  
Ben Bradshaw ◽  
Ruby Sandy ◽  
Silas Nabinacaboo ◽  
Mannie Mameanskum ◽  
...  
Keyword(s):  
Indigenous Peoples ◽  
Well Being ◽  
Aboriginal Community ◽  
Self Monitoring ◽  
Community Engaged Research ◽  
The Past ◽  
Mineral Development ◽  
Iron Deposits ◽  
Term Monitoring

The Naskapi Nation of Kawawachikamach is an Aboriginal community located in northern Quebec near the Labrador Border. Given the region’s rich iron deposits, the Naskapi Nation has considerable experience with major mineral development, first in the 1950s to the 1980s, and again in the past decade as companies implement plans for further extraction. This has raised concerns regarding a range of environmental and socio-economic impacts that may be caused by renewed development. These concerns have led to an interest among the Naskapi to develop a means to track community well-being over time using indicators of their own design. Exemplifying community-engaged research, this paper describes the beginning development of such a tool in fall 2012—the creation of a baseline of community well-being against which mining-induced change can be identified. Its development owes much to the remarkable and sustained contribution of many key members of the Naskapi Nation. If on-going surveying is completed based on the chosen indicators, the Nation will be better positioned to recognize shifts in its well-being and to communicate these shifts to its partners. In addition, long-term monitoring will allow the Naskapi Nation to contribute to more universal understanding of the impacts of mining for Indigenous peoples.

Courting the Youth Vote in 2008: The Obama Effect

2009 ◽  
Vol 5 ◽  
Author(s):  
Lindsey C Bohl
Keyword(s):  
Presidential Elections ◽  
Voter Registration ◽  
The Internet ◽  
The Past ◽  
Several Variables ◽  
High Turnout ◽  
Short And Long Term ◽  
Use Of The Internet ◽  
Youth Vote

This paper examines a few of the numerous factors that may have led to increased youth turnout in 2008 Election. First, theories of voter behavior and turnout are related to courting the youth vote. Several variables that are perceived to affect youth turnout such as party polarization, perceived candidate difference, voter registration, effective campaigning and mobilization, and use of the Internet, are examined. Over the past 40 years, presidential elections have failed to engage the majority of young citizens (ages 18-29) to the point that they became inclined to participate. This trend began to reverse starting in 2000 Election and the youth turnout reached its peak in 2008. While both short and long-term factors played a significant role in recent elections, high turnout among youth voters in 2008 can be largely attributed to the Obama candidacy and campaign, which mobilized young citizens in unprecedented ways.

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