Dermatological treatments

2020 ◽  
pp. 27-46
Keyword(s):  
Skin Disease ◽  
Adverse Reactions ◽  
Calcineurin Inhibitors ◽  
Body Site ◽  
Topical Corticosteroids ◽  
The Common ◽  
Topical Treatments ◽  
Skin Conditions ◽  
Scaly Skin ◽  
Systemic Therapies

Dermatological treatments cover the common topical treatments, including emollients, corticosteroids, calcineurin inhibitors, keratolytics, and psoriasis products, as well as adverse reactions to topical treatments and an overview of phototherapy (ultraviolet light) and systemic therapies for severe skin disease in children. A summary of the different bases used for topical medicaments is explained. The different potency of topical corticosteroids and which to choose based on body site and severity of inflammation is discussed, as well as appropriate quantities to use. A useful list of available preparations is included. Topical treatments for psoriasis are reviewed. Emollients for dry and scaly skin conditions are discussed and a list of common preparations in order of greasiness is included. Sunscreen options are explained and adverse reactions to topical therapies included. An overview of bandages used for wet wraps is summarized. There is a summary of the more commonly used systemic therapies for severe skin disease in children, including a brief mention of the use of biologics.

Management of skin disease

2020 ◽  
pp. 5761-5772
Author(s):  
Rod Sinclair
Keyword(s):  
Human Papillomavirus ◽  
Skin Disease ◽  
Topical Therapy ◽  
Local Treatment ◽  
Calcineurin Inhibitors ◽  
Immunomodulatory Drugs ◽  
Papillomavirus Infections ◽  
Basal Cell Carcinomas ◽  
Topical Treatments ◽  
Anti Inflammatory

Topical therapy of skin disease employs a vehicle (ointments, creams, lotions, gels) to deliver an active ingredient to the skin, to provide a protective barrier, or to hydrate and moisturize the skin. There are many types of topical treatments, including antipruritics, are used to relieve itching; keratolytics are used to remove hyperkeratotic skin; tars act by reducing the thickness of the epidermis; corticosteroids have anti-inflammatory and immunosuppressive effects that are useful in treating many skin disorders; calcipotriol reduces epidermal proliferation and is used in local treatment of plaque psoriasis; calcineurin inhibitors for eczema and other diseases; retinoids influence immune function and have some anti-inflammatory activity and are used in acne; immunomodulatory drugs such as imiquimod for some human papillomavirus infections, superficial basal cell carcinomas, and other diseases.

scholarly journals “The role of Tulsi plant in management of Alasaka kushtha – A literature review.”

2021 ◽  
Vol 5 (02) ◽  
Author(s):  
Eshwari S. Paratkar ◽  
Suryaprakash K. Jaisal ◽  
M.S. Jaiswal
Keyword(s):  
Skin Disease ◽  
Skin Diseases ◽  
Healthy Lifestyle ◽  
Ocimum Sanctum ◽  
Regular Consumption ◽  
Complex Chemical Composition ◽  
The Common ◽  
Chronic Skin ◽  
Skin Conditions

There are many skin disease which is most common among all skin diseases worldwide. Chronic skin conditions are typically not curable, but they can be managed using proper drugs and by paying close attention to lifestyle. Ayurveda focuses on healthy lifestyle practices and regular consumption of adaptogenic herbs. This study is focusing on getting knowledge of the role of Tulsi plant in Alasaka kushta by review of samhitas, research articles, published articles, and websites. In Ayurved samhitas various skin diseases are comes under different classification. Some skin diseases are comes under kshudra kushtha. Alasaka kushtha comes under kshudra kushta in some Ayurvedic  samhitas. Dravya guna is one of the pharmaco-therapeutic branch of Ayurveda deals with herbal drugs. The plant Ocimum sanctum better known as Tulsi or Holy basil can be used for everything from the common cold to heart disorder due to its highly complex chemical composition. Perhaps best known of many active compounds that have been identified and extracted from the Tulsi plant. Tulsi herb can also cure variety of skin disease. Therefore called as “Herb for all reason”.

Vitiligo: An Updated Narrative Review

2020 ◽  
Vol 16 ◽  
Author(s):  
Alexander K. C. Leung ◽  
Joseph M. Lam ◽  
Kin Fon Leong ◽  
Kam Lun Hon
Keyword(s):  
Present Article ◽  
English Literature ◽  
Disease Onset ◽  
Clinical Manifestations ◽  
Calcineurin Inhibitors ◽  
Ultraviolet B ◽  
Lower Limbs ◽  
Treatment Modalities ◽  
Topical Corticosteroids ◽  
Topical Calcineurin Inhibitors

Background: Vitiligo is a relatively common acquired pigmentation disorder that can cause significant psychological stress and stigmatism. Objective: This article aims to familiarize physicians with the clinical manifestations, evaluation, diagnosis, and management of vitiligo. Methods: A Pubmed search was conducted in Clinical Queries using the key term "vitiligo". The search included metaanalyses, randomized controlled trials, clinical trials, observational studies, and reviews. The search was restricted to the English literature. The information retrieved from the above search was used in the compilation of the present article. The information retrieved from the above search was used in the compilation of the present article. Results: Approximately one quarter of patients with vitiligo have the onset before 10 years of age. Genetic, immunological, neurogenic and environmental factors may have a role to play in the pathogenesis. Vitiligo typically presents as acquired depigmented, well-demarcated macules/patches that appear milk- or chalk-white in color. Lesions tend to increase in number and enlarge centrifugally in size with time. Sites of predilection include the face, followed by the neck, lower limbs, trunk, and upper limbs. The clinical course is generally unpredictable. In children with fair skin, no active treatment is usually necessary other than the use of sunscreens and camouflage cosmetics. If treatment is preferred for cosmesis, topical corticosteroids, topical calcineurin inhibitors, and narrowband ultraviolet B phototherapy are the mainstays of treatment. Conclusion: The therapeutic effect of all the treatment modalities varies considerably from individual to individual. As such, treatment must be individualized. In general, the best treatment response is seen in younger patients, recent disease onset, darker skin types, and head and neck lesions. Topical corticosteroids and calcineurin inhibitors are the treatment of choice for those with localized disease. Topical calcineurin inhibitors are generally preferred for lesions on genitalia, intertriginous areas, face, and neck. Narrowband ultraviolet B phototherapy should be considered in patients who have widespread vitiligo or those with localized vitiligo associated with a significant impact on the quality of life who do not respond to treatment with topical corticosteroids and calcineurin inhibitors.

scholarly journals ‘Not just a piece of skin in front of you’—a qualitative exploration of the experiences of adolescents with eczema and psoriasis with healthcare professionals

BMJ Open ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. e041108
Author(s):  
Isabella Joy de Vere Hunt ◽  
Abigail McNiven ◽  
Amanda Roberts ◽  
Himesh Parmar ◽  
Tess McPherson
Keyword(s):  
Young People ◽  
Skin Disease ◽  
Healthcare Professionals ◽  
Healthcare Delivery ◽  
Healthcare Providers ◽  
Secondary Analysis ◽  
Emotional Impact ◽  
Skin Conditions ◽  
The Uk ◽  
Qualitative Exploration

BackgroundThere is little qualitative research in the UK focussing on adolescents’ experience of their healthcare providers, and inflammatory skin conditions are a common heath problem in adolescence.AimTo explore the experiences of adolescents with eczema and psoriasis with healthcare professionals, and to distil the participants’ key messages for their healthcare providers.DesignThis is a secondary thematic analysis of interviews with adolescents with eczema or psoriasis.ParticipantsThere were a total of 41 text transcripts of interviews with young people with eczema or psoriasis who had given permission for secondary analysis; 23 of the participants had eczema, and 18 psoriasis. Participants were living in the UK at time of interview, and aged 15–24 years old.ResultsWe have distilled the following key messages from young people with eczema and psoriasis for healthcare providers: (1) address the emotional impact; (2) give more information, with the subtheme and (3) appreciate patient research. We identified the following eczema-specific themes: (ECZ-4) ‘It’s not taken seriously’; (ECZ-5) offer choice in treatment and (ECZ-6) lack of structure/conflicting advice. Two psoriasis-specific themes were identified: (PSO-4) feeling dehumanised/treat me as a person; and (PSO-5) think about how treatments will affect daily life.ConclusionThis qualitative data analysis highlights the need for greater recognition of the emotional impact of skin disease in adolescence, and for more comprehensive provision of information about the conditions. We call for greater sensitivity and flexibility in our approach to adolescents with skin disease, with important implications for healthcare delivery to this group.

scholarly journals Evaluation of medicines advertising in medical journals

2009 ◽  
Vol 45 (2) ◽  
pp. 303-312
Author(s):  
Daliana Maria Berenice de Oliveira Souza ◽  
Suellen Cristiane Medeiros de Lima ◽  
Almária Mariz Batista ◽  
Maria Cleide Ribeiro Dantas de Carvalho
Keyword(s):  
Side Effects ◽  
Adverse Reactions ◽  
Healthcare Professionals ◽  
Scientific Information ◽  
Medical Prescription ◽  
Medical Journals ◽  
Registration Number ◽  
The Common

This work intended to analyze the advertising of medicines requiring medical prescription, divulged into three journals of the neurology and cardiology areas addressed to healthcare professionals. The analysis was based on current legislation, among other criteria, as well as specific literature. The presence of the following items was investigated: registration number, drug name, specific indications, contraindications; cautions and warnings; adverse reactions; possible side effects; posology; legibility of technical-scientific information and bibliographic references, phrases and/or expressions about the medication benefits, as compared to other drugs; safety warnings, healing promises and pictures of people smiling, and the quotations confirmation based on bibliographic references. Among the evaluated legal criteria, it was observed the absence of legibility in technical-scientific information in 85% of advertisements; absence of side effects in 23%; absence of cautions and warnings in 15%; of contraindications in 12.8%; of posology in 6.4%; of registration numbers in 2.7% and of the Common Brazilian Denomination/Common International Denomination (Denominação Comum Brasileira/Denominação Comum Internacional - DCB/DCI) in 0.6%. Out of 130 statements respecting advantages face to others drugs, 23.8% were not confirmed and out of 48 divulged safety messages, 41.7% could not be found in quoted references. The pictures of people smiling was a resource used in 42.2% of advertisements. Out of 1362 references analyzed, 19.7% were not found and 37.1% of quoted affirmations weren't confirmed.

scholarly journals Anti-inflammatory potency testing of topical corticosteroids and calcineurin inhibitors in human volunteers sensitized to diphenylcyclopropenone

2018 ◽  
Vol 84 (8) ◽  
pp. 1719-1728 ◽  
Author(s):  
Kristian F. Mose ◽  
Flemming Andersen ◽  
Mads A. Røpke ◽  
Lone Skov ◽  
Peter S. Friedmann ◽  
...  
Keyword(s):  
Calcineurin Inhibitors ◽  
Topical Corticosteroids ◽  
Human Volunteers ◽  
Anti Inflammatory

Dry skin disorders

2020 ◽  
pp. 403-416
Keyword(s):  
Clinical Sign ◽  
Underlying Mechanism ◽  
Skin Disorders ◽  
Dry Skin ◽  
Netherton Syndrome ◽  
Collodion Baby ◽  
Harlequin Ichthyosis ◽  
The Common ◽  
Scaly Skin ◽  
Recessive Ichthyosis

This chapter on dry skin disorders describes a range of mainly genetic dermatoses whose predominant feature is dry scaly skin. It excludes conditions such as eczema where dry skin is a secondary clinical sign. The underlying mechanism of dry scaly skin is briefly discussed and an algorithm points to possible diagnoses. The focus is on the genetic ichthyoses, defined as congenital, lifelong, generalized dry and scaly skin. The common ichthyoses are non-inflammatory (ichthyosis vulgaris and X-linked recessive ichthyosis) but there are several inflammatory ichthyoses, some associated with fragile skin (blistering) and several with multisystem complications, such as Netherton syndrome. Salient features of each are reviewed with illustrations of selected cases and management is outlined. Two important neonatal presentations, collodion baby and harlequin ichthyosis, are described.

Pustular rashes

2020 ◽  
pp. 291-300
Keyword(s):  
Skin Disease ◽  
Systemic Disease ◽  
The Body ◽  
Pustular Psoriasis ◽  
Dermatophytic Fungi ◽  
The Common

This chapter describes the common pustular rashes that occur in children. This includes infective causes due to bacteria such as staphylococcus, streptococcus, and pseudomonas, dermatophytic fungi, viruses, parasites, and yeasts. Non-infective causes include primary skin disease such as acne, pustular psoriasis, and neonatal pustular conditions as well as systemic disease and drugs. The chapter lists all the diseases then discusses them according to the body sites that are most commonly affected. A brief clinical summary of each condition is then provided with cross references to other relevant sections of the book.

Management of skin disease

2010 ◽  
pp. 4731-4740
Author(s):  
Rod Sinclair
Keyword(s):  
Salicylic Acid ◽  
Benzoyl Peroxide ◽  
Active Ingredient ◽  
Plaque Psoriasis ◽  
Skin Disease ◽  
Topical Therapy ◽  
Local Treatment ◽  
Skin Disorders ◽  
Topical Treatments ◽  
Anti Inflammatory

Topical therapy employs a vehicle (ointments, creams, lotions, gels) to deliver an active ingredient to the skin, to provide a protective barrier, or to hydrate and moisturize the skin. There are many types of topical treatments, including (1) antipruritics, e.g. calamine, are used to relieve itching; (2) keratolytics, e.g. salicylic acid, urea, are used to remove hyperkeratotic skin; (3) tars act by reducing the thickness of the epidermis; (4) corticosteroids have anti-inflammatory and immunosuppressive effects that are useful in treating many skin disorders; (5) calcipotriol (an analogue of 1,25-dihydroxycholecalciferol) reduces epidermal proliferation and is used in local treatment of plaque psoriasis; (6) retinoids influence immune function and have some anti-inflammatory activity and are used in acne; (7) antiseptics, e.g. benzoyl peroxide, chlorhexidine; (8) antifungal agents; (9) sunscreens; (10) anaesthetics/analgesics....

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