Pituitary tumours

2017 ◽  
Author(s):  
Edward R. Laws ◽  
Whitney W. Woodmansee ◽  
Jay S. Loeffler
Keyword(s):  
Radiation Therapy ◽  
Surgical Management ◽  
Visual Loss ◽  
Multidisciplinary Approach ◽  
Pituitary Hormones ◽  
Laboratory Evaluation ◽  
Multidisciplinary Management ◽  
Effective Solution ◽  
Benign Lesions ◽  
Pituitary Tumours

Pituitary tumours are common, usually benign, lesions ordinarily well controlled by multidisciplinary management. The several subtypes of pituitary tumours reflect the hormones produced by the pituitary gland, and each may require a complex sequential programme of treatment. Modern laboratory evaluation and imaging is capable of extensively characterizing the tumours, and is the basis for the recommended therapies. The tumours that produce excess active levels of pituitary hormones may be amenable to very satisfactory medical therapy, which reduces hormone levels towards normal, and often causes shrinkage of the tumour. Surgical management is appropriate for tumours that are not producing excess hormones but by nature of their bulk can compress the optic nerves and cause visual loss. These tumours respond well to surgical management, which is usually done using the transnasal, transsphenoidal route of access. Patients with persistent or recurrent tumours and persistent hormonal excess can be effectively treated with modern techniques of radiation therapy. A multidisciplinary approach with specialists from different fields concentrating on the patient and the problem offers a comprehensive and effective solution for most patients with pituitary disorders.

scholarly journals Multidisciplinary Management of Pituitary Apoplexy

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Adriana Albani ◽  
Francesco Ferraù ◽  
Filippo Flavio Angileri ◽  
Felice Esposito ◽  
Francesca Granata ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Pituitary Gland ◽  
Multidisciplinary Approach ◽  
Pituitary Apoplexy ◽  
Clinical Syndrome ◽  
Surgical Decompression ◽  
Medical Emergency ◽  
Multidisciplinary Management ◽  
Pituitary Tumours ◽  
Haemorrhagic Necrosis

Pituitary apoplexy is a rare clinical syndrome due to ischemic or haemorrhagic necrosis of the pituitary gland which complicates 2–12% of pituitary tumours, especially nonfunctioning adenomas. In many cases, it results in severe neurological, ophthalmological, and endocrinological consequences and may require prompt surgical decompression. Pituitary apoplexy represents a rare medical emergency that necessitates a multidisciplinary approach. Modalities of treatment and times of intervention are still largely debated. Therefore, the management of patients with pituitary apoplexy is often empirically individualized and clinical outcome is inevitably related to the multidisciplinary team’s skills and experience. This review aims to highlight the importance of a multidisciplinary approach in the management of pituitary apoplexy and to discuss modalities of presentation, treatment, and times of intervention.

Multidisciplinary Management of Postoperative Pancreatic Fistula

2021 ◽  
Author(s):  
Alexa Glencer ◽  
Kim Kirkwood ◽  
Adam Schwertner ◽  
Cody Keller ◽  
Mustafa Arain ◽  
...  
Keyword(s):  
Interventional Radiology ◽  
Pancreatic Fistula ◽  
Multidisciplinary Approach ◽  
Postoperative Morbidity ◽  
Postoperative Pancreatic Fistula ◽  
Significant Source ◽  
Successful Outcome ◽  
Multidisciplinary Management ◽  
Economic Strain ◽  
Pancreatic Fistulas

AbstractPostoperative pancreatic fistulas are complex, challenging problems that often take weeks, months, or longer to resolve. Multiple interventions may be required to achieve a successful outcome. As such, resolution typically involves a multidisciplinary approach by a team whose skills include abdominal imaging, specialized surgery, advanced endoscopy, and interventional radiology. Intensive resources and time are often required, which impacts both patients and their caregivers. While treatment(s) continue to improve, a primary goal of research efforts in this area is the prevention of this significant source of postoperative morbidity, mortality, and economic strain.

Multidisciplinary Management of a ‘Double Tooth’

Dental Update ◽  
2021 ◽  
Vol 48 (4) ◽  
pp. 266-270
Author(s):  
Niraj Halai ◽  
Shash Bhakta
Keyword(s):  
Clinical Diagnosis ◽  
Clinical Relevance ◽  
Multidisciplinary Approach ◽  
Case Reports ◽  
Multidisciplinary Management ◽  
Neutral Term

The term double tooth has often replaced the clinical diagnosis of gemination or fusion. If teeth have been extracted or exfoliated, the use of the neutral term ‘double tooth’ avoids the need to arbitrarily decide if it was gemination or fusion in origin. This case reports on a 16-year-old male who presented with an UL2 ‘double tooth’ and his combined restorative, surgical and orthodontic intervention to achieve his ideal result. CPD/Clinical Relevance: A multidisciplinary approach should be adopted when treating patients with a double tooth and an appropriate protocol as cited can be used.

TISSUE CULTURE STUDIES ON HUMAN PITUITARY TUMOURS: RADIOIMMUNOASSAYABLE ANTERIOR PITUITARY HORMONES IN THE CULTURE MEDIUM

1978 ◽  
Vol 88 (2) ◽  
pp. 239-249 ◽  
Author(s):  
Loren G. Lipson ◽  
Inese Z. Beitins ◽  
Paul D. Kornblith ◽  
Janet W. Mc Arthur ◽  
Henry G. Friesen ◽  
...  
Keyword(s):  
Tissue Culture ◽  
Cushing’S Disease ◽  
Anterior Pituitary ◽  
Pituitary Hormones ◽  
Cushing's Disease ◽  
Hormone Release ◽  
Pituitary Tumours ◽  
Human Pituitary ◽  
Anterior Pituitary Hormones

ABSTRACT A tissue culture study was undertaken to determine if human non-functioning pituitary tumours secrete polypeptide anterior pituitary hormones in vitro and to study the spectrum of hormone release by functioning pituitary neoplasms. Fragments from 48 human pituitary tumours (from patients - 2 with Cushing's disease, 1 with Nelson's syndrome, 5 with amenorrhoea-galactorrhoea, 10 with acromegaly and 30 with non-functioning pituitary tumours) and three normal human anterior pituitary glands (controls) were placed in tissue culture immediately after surgery. The in vitro release of human growth hormone (HGH), prolactin (Prl), thyrotrophin (TSH), adrenocorticotrophin (ACTH), luteinizing hormone (LH) and follicle stimulating hormone (FSH) were measured by radioimmunoassays at the end of one week in culture. Clinical and pathological data were compared to hormone release patterns. In the culture media from control pituitaries the concentrations of the six hormones tested were 100 to 10 000 times greater than in peripheral blood. The medium surrounding the fragments from functioning pituitary tumours contained the following: a) Acromegaly - high levels of HGH and variable concentrations of the other hormones. b) Cushing's disease - ACTH and Prl predominantly. c) Amenorrhcea-galactorrhoea syndrome - prolactin in 4 out of 5 patients, all six polypeptides in one patient. In the media from the 30 patients diagnosed as having non-functioning pituitary tumours, 60 % of the samples contained at least one hormone at a concentration similar to that of the controls and 100 % of the samples contained detectable quantities of at least one hormone.

A multidisciplinary management approach for patients with Klippel-Trenaunay syndrome and multifetal gestation with successful outcomes

2018 ◽  
Vol 7 (2) ◽  
Author(s):  
James Hogg ◽  
Rebecca Pollack ◽  
Courtney Stephenson ◽  
Lorene Temming
Keyword(s):  
Multidisciplinary Approach ◽  
Congenital Disorder ◽  
Neonatal Outcomes ◽  
Management Approach ◽  
Multidisciplinary Management ◽  
Lymphatic Malformations ◽  
Multiple Gestations ◽  
Adverse Neonatal Outcomes ◽  
Maternal And Neonatal Outcomes ◽  
Klippel Trenaunay Syndrome

Abstract Background Klippel-Trenaunay syndrome (KTS) is a complex congenital disorder characterized by the classic triad of capillary malformation, venous and lymphatic malformations and limb overgrowth. The incidence of pregnancies affected by KTS is unknown. There is a paucity of literature regarding management and outcomes of affected pregnancies, particularly in multifetal gestations. Case We present two cases of pregnancies affected by KTS and multiple gestations. A multidisciplinary approach with hematology, radiology and anesthesia resulted in two successful pregnancies with no adverse neonatal outcomes. Conclusion Management of pregnancies affected by KTS and multiple gestations should be personalized with a multi-disciplinary approach to avoid morbidity and improve maternal and neonatal outcomes.

Multidisciplinary management of patients with pubic osteomyelitis, a rare but serious complication after surgery and radiation therapy for advanced gynaecological cancer

2021 ◽  
Vol 14 (1) ◽  
pp. e236289
Author(s):  
Ilse Haveman ◽  
Anne M van Altena ◽  
Charlotte PA Verschuren ◽  
Johanna WM Aarts
Keyword(s):  
Radiation Therapy ◽  
Multidisciplinary Approach ◽  
Late Onset ◽  
Wound Dehiscence ◽  
Vulvar Pain ◽  
Vaginal Carcinoma ◽  
Pelvic Area ◽  
The Impact

Pubic osteomyelitis is a rare and often late-onset complication of radiation therapy and surgery for vulvar and vaginal carcinoma. It typically presents with vulvar pain, fever, vaginal discharge and/or gait disorders. Pubic osteomyelitis is often accompanied by fistulas or wound dehiscence in the pelvic area. Its accurate diagnosis and treatment are challenging and require a multidisciplinary team effort. In our patients, multiple combined surgical procedures, long-term antibiotic treatment and days to weeks of hospital admission were necessary to treat pubic osteomyelitis. We emphasise the importance of timely and adequate diagnosis and multidisciplinary approach resulting in a course of treatment that is as effective as possible, limiting the impact on quality of life, which is generally high in this group of patients.

Pericardial masses and congenital abnormalities

ESC CardioMed ◽  
2018 ◽  
pp. 1582-1584
Author(s):  
Angelos G. Rigopoulos ◽  
Hubert Seggewiss
Keyword(s):  
Computed Tomography ◽  
Surgical Management ◽  
Congenital Abnormalities ◽  
Benign Lesions ◽  
Chest Computed Tomography ◽  
X Ray ◽  
Wall Calcification ◽  
Chest X Ray ◽  
Pericardial Cysts ◽  
The Right

Pericardial masses include cysts, pericardial tumours, and pericardial haematomas. Pericardial cysts are benign lesions commonly located in the right cardiophrenic angle that remain typically asymptomatic and are incidentally found in chest X-ray or chest computed tomography but might cause pressure symptoms or become infected, thus requiring surgical management. Hydatid cysts due to echinococcosis are the most common acquired pericardial cysts, characterized by wall calcification, and indicate surgery.

Overview of Infectious Uveitis and Clinical Findings

2019 ◽  
pp. 223-229
Keyword(s):  
Early Treatment ◽  
Visual Loss ◽  
Treatment Success ◽  
Clinical Findings ◽  
Laboratory Evaluation ◽  
Infectious Uveitis

Infectious uveitis caused by bacteria, viruses, fungi, parasites is exogenous uveitis that may cause serious visual loss. Early treatment through clinical findings and appropriate laboratory evaluation is crucial for prognosis and treatment success.

scholarly journals Case Study: The Surgical Management of Angiokeratoma Resulting from Radiotherapy for Penile Cancer

2009 ◽  
Vol 9 ◽  
pp. 339-342 ◽  
Author(s):  
Rowland Rees ◽  
Alex Freeman ◽  
Peter Malone ◽  
Giulio Garaffa ◽  
Asif Muneer ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Skin Lesion ◽  
Surgical Management ◽  
Penile Cancer ◽  
External Genitalia ◽  
External Beam Radiation ◽  
Surgical Reconstruction ◽  
External Beam ◽  
Beam Radiation

Angiokeratoma is a rare, benign skin lesion and a recognised complication of radiation therapy. Here we describe a case of extensive angiokeratoma of the groin and external genitalia resulting from external beam radiation to that area in a patient with penile carcinoma. Furthermore, we outline the management of this problem by surgical reconstruction.

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