Combination pelvic rocking exercises with belly dance to reduce labor pain

Background: Labor pain will get more substantial along with the increase in cervical dilatation and can affect the mother's psychological condition and the welfare of the fetus. Pelvic rocking exercises help reduce pain during labor, but the combined pelvic rocking exercises with belly dance for birth have not been studied. In this study, combining pelvic rocking exercises with belly dance for birth as physical preparation and exercise, especially in the pelvic area, can reduce pain effectively and efficiently so that mothers can give birth vaginally.Purpose: Analyze the effect of intervention combination of pelvic rocking exercises with belly dance for birth to pain intensity of first stage the active phase in mother birth.Methods: This is Quasy experimental research with pretest and posttest with control group design. Respondents were primigravida mothers during the first stage of the active phase. Determination of respondents by accidental sampling obtained the treatment group (n=17) and control group (n=17). The intervention was given for 20 minutes every 1 hour during the first stage of the active phase.Result: The combined intervention of pelvic rocking exercises with belly dance for birth was effective in reducing pain intensity as seen from the average decrease in pain intensity every hour, at the 1st hour of 4.0, the 2nd hour of 3.0, the 3rd hour of 2.7, and the 4th hour of 2.6 (p<0.001)Conclusion: The combination of pelvic rocking exercises with belly dance for birth is effective to pain intensity of the first stage, the active phase in women giving birth.

Analysis of the severity of clinical manifestations of endometriosis in the long term after radical surgical treatment

Comparative analysis of the endometriosis main clinical manifestations (pain syndrome in the small pelvic area, menstrual and generative functions disorders, adjacent organs dysfunction) has been carried out in 111 women in long-term period after efficient operative interventions and 371 women with endometriosis who didnt get any treatment. None of the above-mentioned methods of the efficient surgical treatment turned to be optimal (long-term and effective) for cutting short the main clinical manifestations of endometriosis.

The discourse on the intersectionality of religion and HIV and AIDS with specific reference to Thulamela municipality, Limpopo province

The human immunodeficiency virus (HIV) since its genesis has continued to affect a large number of the population in the African region and has caused exponential deaths. At the same time, new infections have been reported in South Africa. However, religion as a vehicle of change through the institution of the church has been acting on the contrary, since it discourages the use of condoms (one of the most effective ways to prevent HIV) and moralising the pelvic area in its characterisation against the commandment of God. Such a perspective has largely been drawn from the Christian doctrine(s). We argue that in its condemnation and moralisation of the virus, the church, through its pastors, engaged in biblical discourse (preaching).Contribution: The article applies a qualitative phenomenological approach and system theory as theoretical lenses. Furthermore, the article locates the study within Christian communities located in Thulamela Municipality, Limpopo province. It proposes Christian practices that can be useful in combating the virus.

Evaluation of Radiographers’ Knowledge, Attitudes, and Performance Regarding Gonadal Shielding in Diagnostic Radiology Examinations: Southern Khorasan Province Hospitals of Iran

Background: Nowadays, ionizing radiation is increasingly used in medicine. One of the most frequent X-ray examinations is pelvic radiography. Gonads are susceptible in the pelvic area. Gonadal shielding (GS) is a useful method to reduce the received dose by gonads. Despite the benefits of using gonadal shielding, it is rarely used by radiographers. Methods: This cross-sectional study was carried out in ten governmental hospitals with 300 radiographs. Results: The radiographers’ knowledge of using GS had a value equal to 59.1%. However, the radiographers did not have enough information on the subject, although their awareness about the significance of GS was acceptable. Conclusions: Although the radiographers believed in the necessity of using GS for pelvic, abdominal, and spine examinations, they used no shields.

237 Incidence and Implications of Disparate Uterine and Ovarian Development Observed Among Heifers Evaluated During the Peripubertal Period

Rapid development in the reproductive tract occurs in the peripubertal period, with variable rates of development of reproductive tissues potentially resulting in perceived disparities in ovarian and uterine development at pre-breeding examination. Data collected from 22,173 heifers evaluated over five consecutive breeding seasons (2014–2018) were analyzed retrospectively to assess relationships between observed disparities in uterine and ovarian development and the timing of conception within the breeding season. Pre-breeding evaluations were conducted 35–45 days prior to breeding. Weight, hip height, and pelvic area were recorded. A single veterinarian conducted all reproductive evaluations via rectal palpation, and heifers were assigned individual scores for ovarian (2=infantile, 3=no significant structures, 4=large follicle and/or corpus luteum) and uterine (2=infantile, 3=mid-sized, distended tract, 4=well-vascularized, distended or coiled tract) development respectively. Heifers received artificial insemination (AI) based on detected estrus following the 14-day MGA-PG protocol. Pregnancy diagnosis was performed via transrectal ultrasonography. Pregnancy rates to AI (P/AI) were greater for scores 4-4 (n = 14,567) in comparison with 3-3 (n=3,941; P &lt; 0.0001) or 2-2 (n = 44; P &lt; 0.0001) and likewise were greater (P &lt; 0.0001) for scores 3-3 in comparison with 2-2. Heifers with disparate scores of 2–3 (n = 38) did not differ (P = 0.53) from those with disparate scores of 3-2 (n = 53) with respect to P/AI, but either disparity was associated with greater (P &lt; 0.01) P/AI relative to scores of 2-2 and reduced P/AI relative to scores of 3-3 (P &lt; 0.01). Scores of 4-3 (1,698) and 3-3 did not differ (P &gt;0.44) in P/AI, but P/AI tended (P = 0.06) to be greater among scores 3–4 (1,832) in comparison with 3-3. Similar (P &gt; 0.33) P/AI was observed among heifers scored 4-4, 4-3, or 3–4. In summary, disparate ovarian and uterine development impacted timing of conception within the breeding season among heifers with lower tract scores. Such disparities were observed among 0.4% of heifers evaluated.

TP7.2.5 Surgeon measured radiological pelvic measurements as a patient selection tool for laparoscopic rectal resection – an aide in early learning curve

Introduction Rectal resections are considered one of the most technically demanding laparoscopic procedures. This study reviews one unit’s rectal cancer resections to determine whether pelvic dimensions measured by the surgeon could aide patient selection for laparoscopic resections. Methods A prospectively maintained database was used to identify rectal cancer resections between April 2015 to March 2018 and patient demographics, BMI, height of tumour and operative details were in extracted. Anteroposterior (Coccygio-pubic) and transverse (interspinous) distance were measured retrospectively on linked Axial & Saggital views on staging CT scans. Tumour dimensions in the respective planes were recorded and relative proportions of tumour to pelvic dimensions calculated. These were correlated to operative approach. Results Our cohort comprised of 70 patients (42 men) with a median BMI of 27 and mean age of 71. While 6 operations were planned as open procedures, 64 were attempted laparoscopically. Of these, 55 were completed laparoscopically and 9 were converted (16%). There was no correlation between gender and operative approach (p = 0.2). Mean BMI for laparoscopic group 28.7 and converted group 30.0 which was not statistically significant (p = 0.32). Conversion was more likely for low tumours (89%). Median tumour to pelvic area proportion was 0.14 laparoscopic compared to 0.03 for open and 0.03 for converted suggesting that bulkier tumours are more likely to need conversion. Discussion None of previously identified factors such as gender and BMI predicted conversion in our cohort individually. Tumour size relative to pelvic dimensions is a simple measure a surgeon could use to guide patient selection.

Participation of Selected Soluble BMP-2 and BMP-7 Bone Morphogenetic Proteins and Their Soluble Type I ALK-1 and Type II BMPR2 Receptors in Formation and Development of Endometriosis

Angiogenesis is considered to be one of the key stages in the development of endometriosis. Recent studies indicate that bone morphogenetic proteins (BMPs) and their receptors (BMPR) may play an important role in the angiogenesis process. In the literature, however, there is a lack of publications concerning binding BMPs and their receptors with the pathogenesis of endometriosis. The aim of the study was to determine the role of soluble bone morphogenetic proteins, BMP-2 and BMP-7, and their receptors, ALK-1 and BMPR2, in the process of the formation and development of endometriosis. Peritoneal fluid was collected in the proliferative phase of the menstrual cycle, from 80 women aged 21–49 years (mean age 31.3 ± 6.7 years) undergoing laparoscopy to determine the causes of primary infertility. The study involved 60 women in the I, II, III, and IV stages of the disease. The reference group consisted of 20 women who did not have endometriosis or other lesions in the pelvic area. The concentration in the peritoneal fluid of women with endometriosis was compared to the concentration of this parameter in the reference group, and a statistically significant reduction in the concentration of the BMP-2 molecule was found, as well as increasing concentrations of BMP-7, ALK-1, and BMPR2. BMP-2 and BMP-7 and their soluble receptors, ALK-1 and BMPR2, are involved in the formation of endometriosis. The changes in the concentrations of most of the tested parameters demonstrated in the study, especially in the early stages of the disease, may indicate the more effective formation of new blood vessels in this period.

Primary Anetoderma and Acquired Cutis Laxa Associated with Glomerulonephritis in a 37-year-old Filipino Male: A Case Report

A 37-year-old Filipino man presented with a 9-month history of sagging skin progressing cephalocaudally from the chin and neck to the axillae, side of the trunk, and pelvic area. This was followed by a 2-month history of increasing serum creatinine levels associated with periorbital and bipedal edema, generalized weakness, decreased appetite, vomiting, and headache. Subsequently, skin-colored, non-tender sac-like plaques appeared on the abdomen, inguinal, and intergluteal areas. Histopathology of the latter lesions showed increased spaces between collagen bundles in the dermis. Staining with Verhoeff-van Gieson revealed focal sparse elastic fibers in the papillary dermis compared to that of the reticular dermis consistent with anetoderma. Further work-up revealed normal ANA titer and low serum C3. Kidney biopsy showed IgG deposition in the tubular basement membrane and trace C3 deposition in the glomerular mesangium, giving a diagnosis of rapid progressive glomerulonephritis. On subsequent follow-up, the sac-like plaques became lax and presented as generalized wrinkling of the skin, raising the question whether cutis laxa and anetoderma are occurring in a spectrum instead as distinct entities. Based on the current review of literature, this is the first reported case of primary anetoderma co-occurring with cutis laxa in a patient with glomerulonephritis. Deposition of immunoglobulins along the elastic fibers could have activated the complement system, mediating the destruction of the elastic fibers, resulting to cutis laxa and anetoderma. This case also considers the possibility of anetoderma and type I acquired cutis laxa occurring either in a spectrum or as distinct diseases in a single patient. Further investigations may identify an ultrastructural pattern that can help differentiate the two entities.

Epithelial Cell Line Derived from Endometriotic Lesion Mimics Macrophage Nervous Mechanism of Pain Generation on Proteome and Metabolome Levels

Endometriosis is a benign disease affecting one in ten women of reproductive age worldwide. Although the pain level is not correlated to the extent of the disease, it is still one of the cardinal symptoms strongly affecting the patients’ quality of life. Yet, a molecular mechanism of this pathology, including the formation of pain, remains to be defined. Recent studies have indicated a close interaction between newly generated nerve cells and macrophages, leading to neurogenic inflammation in the pelvic area. In this context, the responsiveness of an endometriotic cell culture model was characterized upon inflammatory stimulation by employing a multi-omics approach, including proteomics, metabolomics and eicosanoid analysis. Differential proteomic profiling of the 12-Z endometriotic cell line treated with TNFα and IL1β unexpectedly showed that the inflammatory stimulation was able to induce a protein signature associated with neuroangiogenesis, specifically including neuropilins (NRP1/2). Untargeted metabolomic profiling in the same setup further revealed that the endometriotic cells were capable of the autonomous production of 7,8-dihydrobiopterin (BH2), 7,8-dihydroneopterin, normetanephrine and epinephrine. These metabolites are related to the development of neuropathic pain and the former three were found up-regulated upon inflammatory stimulation. Additionally, 12-Z cells were found to secrete the mono-oxygenated oxylipin 16-HETE, a known inhibitor of neutrophil aggregation and adhesion. Thus, inflammatory stimulation of endometriotic 12-Z cells led to specific protein and metabolite expression changes suggesting a direct involvement of these epithelial-like cells in endometriosis pain development.