scholarly journals The search for failed supernovae with the Large Binocular Telescope: a new candidate and the failed SN fraction with 11 yr of data

2021 ◽  
Vol 508 (1) ◽  
pp. 516-528
Author(s):  
J M M Neustadt ◽  
C S Kochanek ◽  
K Z Stanek ◽  
C Basinger ◽  
T Jayasinghe ◽  
...  
Keyword(s):  
Large Amplitude ◽  
Good Explanation ◽  
Nearby Galaxies ◽  
Optical Wavelengths ◽  
A Current

ABSTRACT We present updated results of the Large Binocular Telescope Search for Failed Supernovae. This search monitors luminous stars in 27 nearby galaxies with a current baseline of 11 yr of data. We re-discover the failed supernova (SN) candidate N6946-BH1 as well as a new candidate, M101-OC1. M101-OC1 is a blue supergiant that rapidly disappears in optical wavelengths with no evidence for significant obscuration by warm dust. While we consider other options, a good explanation for the fading of M101-OC1 is a failed SN, but follow-up observations are needed to confirm this. Assuming only one clearly detected failed SN, we find a failed SN fraction $f = 0.16^{+0.23}_{-0.12}$ at 90 per cent confidence. We also report on a collection of stars that show slow (∼decade), large amplitude (ΔL/L > 3) luminosity changes.

Psychopathologic aspects of obesity: Psychodiagnostic evaluations of bariatric surgery applicants

2011 ◽  
Vol 26 (S2) ◽  
pp. 714-714
Author(s):  
S. Chiappini ◽  
E. Righino ◽  
C. Ciciarelli ◽  
M. Pettorruso ◽  
G. Conte
Keyword(s):  
Bariatric Surgery ◽  
Weight Loss ◽  
Psychiatric Symptoms ◽  
Psychiatric Evaluation ◽  
Psychiatric Interview ◽  
Negative Factor ◽  
Surgical Evaluation ◽  
A Current ◽  
Transoral Gastroplasty

IntroductionPsychiatrists play an important role as members of the bariatric surgery team. A preoperative psychiatric evaluation is considered as part of a mandatory workup before approving surgery.AimsThis evaluation focuses on the identification of any pre-existing psychiatric disorders among candidates for TOGa[1], a new experimental technique of bariatric surgery, and their correlations with post surgical weight loss.Method45 obese patients underwent a psychiatric interview and several psycho diagnostic questionnaires (SCL-90; HAM-D; HAM-A; EDI; TAS).A follow-up was set each 3 months.ResultsWe found that 34.1% of surgery candidates had a current diagnosis of depression; the majority showed anxiety symptoms. We also documented dissatisfaction about body shape, desire of slimness, fear of maturity, perfectionism, bulimia and binge eating disorder. Other frequent psychiatric symptoms were somatization, sensitivity, obsession and compulsion. After 3 months from surgery we found that the best weight loss was associated to low score in HAM-A, high score in hanger-hostility item (SCL-90) and low score in sensitiveness item (SCL-90).ConclusionThe diagnosis of a psychiatric pathology during the pre-surgical evaluation can be considered a predictive negative factor for the outcome of the surgery. The predictive positive factors are firstly the nonexistence of psychiatric symptoms, secondly the high score in sensitiveness-insight item (SCL-90) and the high score in the ability to express feelings. [1] (TransOral Gastroplasty)

Large-Amplitude Circadian Variations of Urinary Neopterin in Healthy Man

Pteridines ◽  
1989 ◽  
Vol 1 (1) ◽  
pp. 17-18 ◽  
Author(s):  
A. Auzeby ◽  
A. Bogdan ◽  
Z. Krosi ◽  
Y. Touitou
Keyword(s):  
T Cell Activation ◽  
Large Amplitude ◽  
Cell Activation ◽  
Good Health ◽  
Circadian Variations ◽  
Young Males ◽  
Urinary Neopterin ◽  
Total Urine ◽  
Healthy Males

Summary Urinary neopterin (Neo), a marker of T-cell activation was measured in five healthy males for a chronobiological study. Five young males mean age: 25 ± 2 (years ± SD) in apparent good health volunteered for the study. Total urine voidings were collected 4-hourly by each individual during a 48 h span at fixed clock hours. The study was carried out during 3 different 48 hours, one week apart. Neopterin was measured by HPLC and results were expressed as the ratio !lmol/mol creatinine.A statistically significant rhythm of neopterin was detected with a peak (Neo = 167.4 ± 33 .8 SD) at 06h30 and a trough (Neo = 110.9 ± 26.9) between 10h30 and 22h30. These results clearly show a 51 % total yariability of neopterin and must be kept in mind when assaying neopterin for clinical exploration. It is therefore imperative to use, in a given patient, the same time-qualified voidings (preferably the first morning one) in order to avoid misinterpretation in the follow-up of patients.

Lactulose in the Management of Constipation: A Current Review

1992 ◽  
Vol 26 (10) ◽  
pp. 1277-1282 ◽  
Author(s):  
Theresa V. Kot ◽  
Ngaire A. Pettit-Young
Keyword(s):  
Clinical Trials ◽  
Adverse Effects ◽  
Clinical Studies ◽  
Data Extraction ◽  
Point Of View ◽  
Data Synthesis ◽  
Study Selection ◽  
Beneficial Response ◽  
A Current

OBJECTIVE: To review the current published clinical studies evaluating the clinical efficacy and safety of lactulose compared with other laxatives or placebo. Adverse effects associated with lactulose are also reported. DATA SOURCES: Information was retrieved by searching the MEDLINE and EMBASE databases for clinical trials, abstracts, conference proceedings, and review articles dealing with lactulose. STUDY SELECTION: Emphasis was placed on clinical trials where lactulose was compared with other laxatives or placebo in patient populations where the diagnosis of constipation was reasonably established. DATA EXTRACTION: The methodology and results from clinical studies were evaluated. Assessment of the studies was made based on diagnosis of constipation, prior management of patients, follow-up of patients, dosage, and adverse effects. DATA SYNTHESIS: Clinical trials in geriatric patients, terminally ill patients, children, and normal and constipated subjects were reviewed. In most instances, lactulose was compared with a placebo, without incorporating the current education on dietary techniques for improving defecation. CONCLUSIONS: Generally, clinical trials have demonstrated a beneficial response compared with placebo, although sometimes that response has been only marginally better, from a clinical point of view.

scholarly journals Local star-forming dwarf galaxies as windows on reionization-era stellar populations

2019 ◽  
Vol 15 (S352) ◽  
pp. 316-316
Author(s):  
Peter Senchyna
Keyword(s):  
Line Emission ◽  
Stellar Populations ◽  
Star Forming ◽  
Star Models ◽  
Relative Paucity ◽  
High Ionization ◽  
Low Metallicity ◽  
Nearby Galaxies ◽  
A New Technique

AbstractThe recent detections of high-ionization nebular line emission from species including CIV in a number of z > 6 galaxies have highlighted substantial deficiencies in our understanding of metal poor stars. Prominent nebular CIV has never been detected in purely star-forming systems locally, and the massive star models used to model this emission in photoionization codes have not been empirically calibrated below the metallicity of the SMC (20% solar). As a result, we are presently entirely unprepared to correctly interpret nebular emission from metal-poor stars observed with JWST and ALMA in the reionization era. We present results from a multi-pronged ongoing local ultraviolet/optical observation campaign with HST/COS, Keck/ESI, and MMT designed to address this issue by locating and characterizing stellar populations capable of powering such high-ionization emission. This work has already demonstrated that strong nebular CIV can be powered by extremely metal-poor (< 10% solar) massive stars, indicating that we may already have evidence of such low-metallicity populations in the reionization era. However, CIV at the equivalent widths detected at z > 6 remains elusive locally, potentially in part due to the relative paucity of known nearby galaxies at these metallicities with massive stellar populations comparable to those in z > 6 systems. We present a new technique to locate such nearby galaxies, and results from optical follow-up which indicate that a substantial population of highly star- forming metal-poor galaxies likely resides just below the detection limits of previous large spectroscopic surveys.

The Recruitment, Selection, and Training of Blind Vending Stand Operators

1970 ◽  
Vol 64 (10) ◽  
pp. 325-329
Author(s):  
Ronald G. Rice ◽  
John E. Muthard ◽  
Neil S. Dumas
Keyword(s):  
Present Report ◽  
State Agencies ◽  
National Scale ◽  
Selection Procedures ◽  
Rate Of Success ◽  
And Training ◽  
A Current

□ At the present time, there does not seem to be sufficient need to justify the expense of validating a selection battery on a national scale. The results of the questionnaire indicated a current rate of success in rehabilitating VSO's which could not be improved appreciably by a selection battery. The present report provides a current look at the evaluation, selection, training, and follow-up success experienced by state agencies. The feasibility of continuing study of the VSO and the review of possible selection procedures have also been reviewed.

A Desire for Growth? An Exploratory Study of Growth Aspirations Among Nascent Nonprofit Entrepreneurs

2020 ◽  
Vol 49 (4) ◽  
pp. 890-901
Author(s):  
Fredrik O. Andersson
Keyword(s):  
Exploratory Study ◽  
Research Note ◽  
Loss Of Control ◽  
Strong Growth ◽  
Survey Responses ◽  
A Current

This research note examines the growth aspirations, and beliefs about growth, based on survey responses from 57 nascent nonprofit entrepreneurs. About 21% of the respondents displayed strong growth ambitions and 40% declared they do not consider growth a current and/or highly prioritized matter. A majority of the nascent nonprofit entrepreneurs recognized that growth could have both positive and negative implications on their emerging nonprofit. Only 14% perceived growth as a ubiquitous positive feat. Perceived positive implications of growth included enhanced impact and reputation, and some of the perceived negative implications of growth were loss of control and increased workload. Furthermore, drawing on brief follow-up conversations with eight respondents, this research note illuminates how growth preferences can evolve as the nonprofit evolve, and even nonprofit entrepreneurs with clear and explicit aspirations to grow may not have the ability to grow.

scholarly journals Asymptotic Giant Branch Variables in Nearby Galaxies

2018 ◽  
Vol 14 (S343) ◽  
pp. 275-282
Author(s):  
Patricia A. Whitelock
Keyword(s):  
Large Amplitude ◽  
Mass Scale ◽  
Asymptotic Giant Branch ◽  
Infrared Observations ◽  
Chemical Enrichment ◽  
Mira Variables ◽  
James Webb Space Telescope ◽  
Distant Galaxies ◽  
Nearby Galaxies ◽  
Low Mass

AbstractCertain types of large amplitude AGB variable are proving to be powerful distance indicators that will rival Cepheids in the James Webb Space Telescope era of high precision infrared photometry. These are predominantly found in old populations and have low mass progenitors. At the other end of the AGB mass-scale, large amplitude variables, particularly those undergoing hot bottom burning, are the most luminous representatives of their population. These stars are < 1 Gyr old, are often losing mass copiously and are vital to our understanding of the integrated light of distant galaxies as well as to chemical enrichment. However, the evolution of such very luminous AGB variables is rapid and remains poorly understood. Here I discuss recent infrared observations of both low- and intermediate-mass Mira variables in the Local Group and beyond.

Validation of the PROFUND index to predict early post-hospital discharge mortality

QJM ◽  
2019 ◽  
Vol 112 (11) ◽  
pp. 854-860 ◽  
Author(s):  
M D Martín-Escalante ◽  
R Quirós-López ◽  
F Martos-Pérez ◽  
J Olalla-Sierra ◽  
F Rivas-Ruiz ◽  
...  
Keyword(s):  
Internal Medicine ◽  
Length Of Stay ◽  
Prospective Observational Study ◽  
Hospital Admissions ◽  
Medicine Department ◽  
Vital Status ◽  
Diagnostic Categories ◽  
C Statistic ◽  
A Current

Abstract Background The PROFUND index (PI) is a prognostic scale for polypathological patients at 12 months. The objective of the study was to validate the PI as a predictor of 1-year mortality in a current cohort of polypathological patients and analyse its prognostic usefulness in the short-term (1 month and 3 months) after discharge from Internal Medicine. Design We conducted a prospective observational study and all polypathological patients discharged from an Internal Medicine Department between 01 March 2016 and 28 February 2017 were enrolled. Methods The variables recorded for each patient were age, sex, diseases and diagnostic categories defining patients as polypathological patients, PI at discharge, number of hospital admissions, length of stay, vital status at 1 year, and date and place of death if applicable. Follow-up lasted 1 year from the time of enrolment. Results Six hundred and ten polypathological patients were enrolled. Mortality was 41% and the patients who died were older, their length of stay was longer and their PI was higher compared with those who survived. The discrimination of the PI for predicting mortality was good, with a C-statistic of 0.718 [95% confidence interval (CI) 0.67–0.76]. In addition, a subgroup of patients with early mortality after discharge was identified, with a C-statistic of 0.74 (95% CI 0.67–0.80) at 30 days and 0.73 (95% CI 0.68–0.78) at 90 days. Conclusions The PI is a valid tool for predicting early and 1-year mortality in polypathological patients after discharge from Internal Medicine.

Long-term outcome and psychiatric comorbidity of adolescent-onset anorexia nervosa

2019 ◽  
Vol 25 (1) ◽  
pp. 33-44 ◽  
Author(s):  
Susana Andrés-Pepiñá ◽  
Maria Teresa Plana ◽  
Itziar Flamarique ◽  
Sonia Romero ◽  
Roger Borràs ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Control Group ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Increased Risk ◽  
A Current

Objective: To assess the outcome of adolescents with anorexia nervosa (AN) about 20 years after first treatment. Methods: Sixty-two women diagnosed with AN during adolescence were invited to participate. Of these 62 patients, 38 agreed to participate and were assessed with a battery of questionnaires and interviews. A control group of 30 women of similar age was also assessed. Results: Of the patients who completed the full assessment, 13 (34%) presented some degree of eating disorder (ED) at follow-up (10 (26%) met full Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5) criteria for an ED and 3 (8%) showed partial remission of an ED). The remaining 25 (66%) patients had fully recovered from AN. The duration of untreated illness before admission was significantly associated with an increased risk of a current ED (odds ratio (OR) = 3.334 (1.3–8.7); p = .014). Of the patients who had recovered totally from their ED, 24% showed another psychiatric disorder. This percentage rose to 70% in patients with a current ED. Conclusion: Sixty-six percent of adolescents who completed the assessment achieved remission of their AN. Comorbidity was more common in the current ED group. The variable that best predicted complete remission was the number of years without treatment, showing the importance of detection and early intervention.

scholarly journals School-based interventions targeting stigma of mental illness: systematic review

2014 ◽  
Vol 38 (4) ◽  
pp. 164-171 ◽  
Author(s):  
Catriona Mellor
Keyword(s):  
Mental Illness ◽  
Young People ◽  
Strong Evidence ◽  
Positive Impact ◽  
School Based ◽  
Programme Design ◽  
Stigma Of Mental Illness ◽  
School Based Interventions ◽  
A Current

Aims and methodTo systematically review the published literature on the effectiveness of classroom-based interventions to tackle the stigma of mental illness in young people, and to identify any consistent elements within successful programmes.ResultsSeventeen studies were included in the analysis. A minority of studies reported a positive impact on stigma or knowledge outcomes at follow-up and there were considerable methodological shortcomings in the studies reviewed. These interventions varied substanitally in content and delivery. It was not possible to use this data to draw out what aspects make a successful intervention. There is currently no strong evidence to support previous conclusions that these types of intervention work for children and adolescents.Clinical implicationsWhen anti-stigma interventions for young people are rolled out in the future, it is important that the programme design and method of delivery have evidence to prove their effectiveness, and that the audience and setting are the most appropriate to target. There is a current lack of strong evidence to inform this.

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