scholarly journals Out of sight, out of mind? The impact of correlated clustering in substructure lensing

Author(s):  
Alexandres Lazar ◽  
James S Bullock ◽  
Michael Boylan-Kolchin ◽  
Robert Feldmann ◽  
Onur Çatmabacak ◽  
...  

Abstract A promising route for revealing the existence of dark matter structures on mass scales smaller than the faintest galaxies is through their effect on strong gravitational lenses. We examine the role of local, lens-proximate clustering in boosting the lensing probability relative to contributions from substructure and unclustered line-of-sight (LOS) haloes. Using two cosmological simulations that can resolve halo masses of Mhalo ≃ 109 M⊙ (in a simulation box of length Lbox ∼ 100 Mpc) and 107 M⊙ (Lbox ∼ 20 Mpc), we demonstrate that clustering in the vicinity of the lens host produces a clear enhancement relative to an assumption of unclustered haloes that persists to >20 Rvir. This enhancement exceeds estimates that use a two-halo term to account for clustering, particularly within 2 − 5 Rvir. We provide an analytic expression for this excess, clustered contribution. We find that local clustering boosts the expected count of 109 M⊙ perturbing haloes by ${\sim }35{{\ \rm per\ cent}}$ compared to substructure alone, a result that will significantly enhance expected signals for low-redshift (zl ≃ 0.2) lenses, where substructure contributes substantially compared to LOS haloes. We also find that the orientation of the lens with respect to the line of sight (e.g. whether the line of sight passes through the major axis of the lens) can also have a significant effect on the lensing signal, boosting counts by an additional $\sim 50{{\ \rm per\ cent}}$ compared to a random orientations. This could be important if discovered lenses are biased to be oriented along their principal axis.

Author(s):  
Kun Ting Eddie Chua ◽  
Karia Dibert ◽  
Mark Vogelsberger ◽  
Jesús Zavala

Abstract We study the effects of inelastic dark matter self-interactions on the internal structure of a simulated Milky Way (MW)-size halo. Self-interacting dark matter (SIDM) is an alternative to collisionless cold dark matter (CDM) which offers a unique solution to the problems encountered with CDM on sub-galactic scales. Although previous SIDM simulations have mainly considered elastic collisions, theoretical considerations motivate the existence of multi-state dark matter where transitions from the excited to the ground state are exothermic. In this work, we consider a self-interacting, two-state dark matter model with inelastic collisions, implemented in the Arepo code. We find that energy injection from inelastic self-interactions reduces the central density of the MW halo in a shorter timescale relative to the elastic scale, resulting in a larger core size. Inelastic collisions also isotropize the orbits, resulting in an overall lower velocity anisotropy for the inelastic MW halo. In the inner halo, the inelastic SIDM case (minor-to-major axis ratio s ≡ c/a ≈ 0.65) is more spherical than the CDM (s ≈ 0.4), but less spherical than the elastic SIDM case (s ≈ 0.75). The speed distribution f(v) of dark matter particles at the location of the Sun in the inelastic SIDM model shows a significant departure from the CDM model, with f(v) falling more steeply at high speeds. In addition, the velocity kicks imparted during inelastic collisions produce unbound high-speed particles with velocities up to 500 km s−1 throughout the halo. This implies that inelastic SIDM can potentially leave distinct signatures in direct detection experiments, relative to elastic SIDM and CDM.


2020 ◽  
Vol 642 ◽  
pp. A194 ◽  
Author(s):  
D. Gilman ◽  
S. Birrer ◽  
T. Treu

Time delay cosmography uses the arrival time delays between images in strong gravitational lenses to measure cosmological parameters, in particular the Hubble constant H0. The lens models used in time delay cosmography omit dark matter subhalos and line-of-sight halos because their effects are assumed to be negligible. We explicitly quantify this assumption by analyzing mock lens systems that include full populations of dark matter subhalos and line-of-sight halos, applying the same modeling assumptions used in the literature to infer H0. We base the mock lenses on six quadruply imaged quasars that have delivered measurements of the Hubble constant, and quantify the additional uncertainties and/or bias on a lens-by-lens basis. We show that omitting dark substructure does not bias inferences of H0. However, perturbations from substructure contribute an additional source of random uncertainty in the inferred value of H0 that scales as the square root of the lensing volume divided by the longest time delay. This additional source of uncertainty, for which we provide a fitting function, ranges from 0.7 − 2.4%. It may need to be incorporated in the error budget as the precision of cosmographic inferences from single lenses improves, and it sets a precision limit on inferences from single lenses.


2020 ◽  
Vol 495 (1) ◽  
pp. 502-509 ◽  
Author(s):  
Yu Morinaga ◽  
Tomoaki Ishiyama

ABSTRACT Dark matter haloes are formed through hierarchical mergers of smaller haloes in large-scale cosmic environments, and thus anisotropic subhalo accretion through cosmic filaments has some impacts on halo structures. Recent studies using cosmological simulations have shown that the orientations of haloes correlate with the direction of cosmic filaments, and these correlations significantly depend on the halo mass. Using high-resolution cosmological N-body simulations, we quantified the strength of filamentary subhalo accretion for galaxy- and group-sized host haloes (Mhost = 5 × 1011–13 M⊙) by regarding the entry points of subhaloes as filaments and present statistical studies on how the shape and orientation of host haloes at redshift zero correlate with the strength of filamentary subhalo accretion. We confirm previous studies that found the host halo mass dependence of the alignment between orientations of haloes and filaments. We also show that, for the first time, the shape and orientation of haloes weakly correlate with the strength of filamentary subhalo accretion even if the host halo masses are the same. Minor-to-major axial ratios of haloes tend to decrease as their filamentary accretion gets stronger. Haloes with highly anisotropic accretion become more spherical or oblate, while haloes with isotropic accretion become more prolate or triaxial. For haloes with strong filamentary accretion, their major axes are preferentially aligned with the filaments, while their angular momentum vectors tend to be slightly more misaligned.


2020 ◽  
Vol 102 (6) ◽  
Author(s):  
Atınç Çaǧan Şengül ◽  
Arthur Tsang ◽  
Ana Diaz Rivero ◽  
Cora Dvorkin ◽  
Hong-Ming Zhu ◽  
...  

2021 ◽  
pp. 247255522098577
Author(s):  
Andrew X. Zhang ◽  
Katelyn Cassidy ◽  
Göran Dahl ◽  
Kevin Moreau ◽  
Fiona Pachl ◽  
...  

Mass spectrometry-based proteomics profiling is a discovery tool that enables researchers to understand the mechanisms of action of drug candidates. When applied to proteolysis targeting chimeras (PROTACs) such approaches provide unbiased perspectives of the binding, degradation selectivity, and mechanism related to efficacy and safety. Specifically, global profiling experiments can identify direct degradation events and assess downstream pathway modulation that may result from degradation or off-target inhibition. Targeted proteomics approaches can be used to quantify the levels of relevant E3 ligases and the protein of interest in cell lines and tissues of interest, which can inform the line of sight and provide insights on possible safety liabilities early in the project. Furthermore, proteomics approaches can be applied to understand protein turnover and resynthesis rates and inform on target tractability, as well as pharmacokinetics/pharmacodynamics understanding. In this perspective, we survey the literature around the impact of mass spectrometry-based proteomics in the development of PROTACs and present our envisioned proteomics cascade for supporting targeted protein degradation projects.


2006 ◽  
Vol 2 (S235) ◽  
pp. 397-397
Author(s):  
Anna Curir ◽  
Paola Mazzei ◽  
Giuseppe Murante

AbstractThe growth and the evolution of the bar instability in stellar-gaseous disks embedded in a dark matter halo evolving in a cosmological framework is explored. We point out the impact of different gas fractions on the bar formation, inside disks of different disk-to-halo mass ratio.


2019 ◽  
Vol 492 (2) ◽  
pp. 2285-2307 ◽  
Author(s):  
Stijn N B Debackere ◽  
Joop Schaye ◽  
Henk Hoekstra

ABSTRACT The interpretation of upcoming weak gravitational lensing surveys depends critically on our understanding of the matter power spectrum on scales $k \lt 10\, {h\, {\rm Mpc}^{-1}}$, where baryonic processes are important. We study the impact of galaxy formation processes on the matter power spectrum using a halo model that treats the stars and gas separately from the dark matter distribution. We use empirical constraints from X-ray observations (hot gas) and halo occupation distribution modelling (stars) for the baryons. Since X-ray observations cannot generally measure the hot gas content outside r500c, we vary the gas density profiles beyond this radius. Compared with dark matter only models, we find a total power suppression of $1\, {\mathrm{per\ cent}}$ ($5\, {\mathrm{per\ cent}}$) on scales $0.2\!-\!1\, {h\, {\rm Mpc}^{-1}}$ ($0.5\!-\!2\, {h\, {\rm Mpc}^{-1}}$), where lower baryon fractions result in stronger suppression. We show that groups of galaxies ($10^{13} \lt m_{\mathrm{500c}} / (h^{-1}\, \mathrm{M}_{\odot }) \lt 10^{14}$) dominate the total power at all scales $k \lesssim 10\, {h\, {\rm Mpc}^{-1}}$. We find that a halo mass bias of $30\, {\mathrm{per\ cent}}$ (similar to what is expected from the hydrostatic equilibrium assumption) results in an underestimation of the power suppression of up to $4\, {\mathrm{per\ cent}}$ at $k=1\, {h\, {\rm Mpc}^{-1}}$, illustrating the importance of measuring accurate halo masses. Contrary to work based on hydrodynamical simulations, our conclusion that baryonic effects can no longer be neglected is not subject to uncertainties associated with our poor understanding of feedback processes. Observationally, probing the outskirts of groups and clusters will provide the tightest constraints on the power suppression for $k \lesssim 1\, {h\, {\rm Mpc}^{-1}}$.


2018 ◽  
Vol 14 (S344) ◽  
pp. 105-108
Author(s):  
Matteo Mazzarini ◽  
Andreas Just

AbstractWe perform six N-body simulations reproducing the interaction between the Milky Way and its satellite galaxies, in order to address the deposit of satellite debris in the Galactic environment. We find that most of the baryons survive inside their host satellites and that most of the baryonic debris ends up in the inner regions of the Milky Way, in contrast to the more uniform distribution of dark matter debris. We also look at the debris Inertia tensor in the inner regions of the Milky Way and find a lower minor-to-major axis ratio for baryons than dark matter. We plan to explore the phase-space distribution of the debris ending in the Galactic disk and bulge. We also plan further simulations including gas dynamics to study the impact of gas on the process.


2019 ◽  
Vol 485 (2) ◽  
pp. 2179-2193 ◽  
Author(s):  
E Ritondale ◽  
S Vegetti ◽  
G Despali ◽  
M W Auger ◽  
L V E Koopmans ◽  
...  

ABSTRACT We use a sample of 17 strong gravitational lens systems from the BELLS GALLERY survey to quantify the amount of low-mass dark matter haloes within the lensing galaxies and along their lines of sight, and to constrain the properties of dark matter. Based on a detection criterion of 10σ, we report no significant detection in any of the lenses. Using the sensitivity function at the 10σ level, we have calculated the predicted number of detectable cold dark matter (CDM) line-of-sight haloes to be μl = 1.17 ± 1.08, in agreement with our null detection. Assuming a detection sensitivity that improved to the level implied by a 5σ threshold, the expected number of detectable line-of-sight haloes rises to μl = 9.0 ± 3.0. Whilst the current data find zero detections at this sensitivity level (which has a probability of P$^{{\rm 5}\sigma }_{{\rm CDM}}(n_{\rm det}=0)$ = 0.0001 and would be in strong tension with the CDM framework), we find that such a low-detection threshold leads to many spurious detections and non-detections and therefore the current lack of detections is unreliable and requires data with improved sensitivity. Combining this sample with a subsample of 11 SLACS lenses, we constrain the half-mode mass to be log (Mhm) < 12.26 at the 2σ level. The latter is consistent with resonantly produced sterile neutrino masses ms < 0.8 keV at any value of the lepton asymmetry at the 2σ level.


Author(s):  
Francesco Sanfedino ◽  
Daniel Alazard ◽  
Valérie Pommier-Budinger ◽  
Fabrice Boquet ◽  
Alexandre Falcoz

This paper proposes a novel dynamic model of a Reaction Wheel Assembly (RWA) based on the Two-Input Two-Output Port framework, already presented by the authors. This method allows the user to study a complex system with a sub-structured approach: each sub-element transfers its dynamic content to the other sub-elements through local attachment points with any set of boundary conditions. An RWA is modelled with this approach and it is then used to study the impact of typical reaction wheel perturbations on a flexible satellite in order to analyze the micro-vibration content for a high accuracy pointing mission. This formulation reveals the impact of any structural design parameter and highlights the need of passive isolators to reduce the micro-vibration issues. The frequency analysis of the transfer between the disturbance sources and the line-of-sight (LOS) jitter highlights the role of the reaction wheel speed on the flexible modes migration and suggests which control strategies can be considered to mitigate the residual micro-vibration content in order to fulfil the mission performances.


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