scholarly journals FP115KIDNEY BIOPSY IN THE ELDERLY: FRAILTY INDEX IS A GOOD TOOL TO PREDICT CLINICAL OUTCOMES

2018 ◽  
Vol 33 (suppl_1) ◽  
pp. i15-i16
Author(s):  
Vittorio Di Maso ◽  
Elisabetta Ermacora ◽  
Michele Carraro ◽  
Katiuscia Scala ◽  
Giuliano Boscutti
2018 ◽  
Vol 2 (2) ◽  
Author(s):  
Ivany R Rahmadani ◽  
Lazuardhi Dwipa ◽  
Yuni S Pratiwi

Frailty syndrome is a state of decreased body function, thereby increasing susceptibility to poor clinical outcomes. The risks of developing frailty syndrome increase in the elderly at Nursing Home. This study is expected to provide characteristic data of frailty syndrome as the basis for the prevention and management for the elderly. This study is conducted by using a descriptive quantitative design. The data is taken by using FI-40 questionnaire consisting of 40 questions in the elderly at Bandung done by using total sampling. There are 42(58.3%) of pre-frail and 7(9.7%) of frail elderly out of 72 data. Pre-frail prevails mostly in women (29 subjects; 69.1%) and at age of 60-69 years in 18 subjects (42.8%). Frail elderly is found mostly in women (3 subjects; 42.8%) and aged 70-79 years (3 subjects ; (42.8). The most common cause of frailty is eye and foot problems in 7(100%). The most common cause of pre-frail is the assumption of health level in 35(83.3%). This study concludes that frailty syndrome is common among the elderly and special attention must be paid to eye and foot problems.Keywords: elderly, frailty syndrome, FI-40 questionnaire, nursing home


2005 ◽  
Vol 18 (3) ◽  
pp. 446-464 ◽  
Author(s):  
Eduardo Villamor ◽  
Wafaie W. Fawzi

SUMMARY Vitamin A supplementation to preschool children is known to decrease the risks of mortality and morbidity from some forms of diarrhea, measles, human immunodeficiency virus (HIV) infection, and malaria. These effects are likely to be the result of the actions of vitamin A on immunity. Some of the immunomodulatory mechanisms of vitamin A have been described in clinical trials and can be correlated with clinical outcomes of supplementation. The effects on morbidity from measles are related to enhanced antibody production and lymphocyte proliferation. Benefits for severe diarrhea could be attributable to the functions of vitamin A in sustaining the integrity of mucosal epithelia in the gut, whereas positive effects among HIV-infected children could also be related to increased T-cell lymphopoiesis. There is no conclusive evidence for a direct effect of vitamin A supplementation on cytokine production or lymphocyte activation. Under certain circumstances, vitamin A supplementation to infants has the potential to improve the antibody response to some vaccines, including tetanus and diphtheria toxoids and measles. There is limited research on the effects of vitamin A supplementation to adults and the elderly on their immune function; currently available data provide no consistent evidence for beneficial effects. Additional studies with these age groups are needed.


Author(s):  
В.А. Белобородов ◽  
И.А. Степанов ◽  
А.В. Щербатых ◽  
И.И. Томашов ◽  
З.С. Саакян ◽  
...  

В отечественной и зарубежной специализированной литературе отсутствуют исследования, посвященные изучению факторов риска развития неблагоприятного исхода у пациентов старшей возрастной группы с инсультассоциированной нозокомиальной пневмонией. Цель исследования - изучение факторов риска развития неблагоприятного клинического исхода у пациентов пожилого и старческого возраста с нозокомиальной пневмонией на фоне ОНМК. В исследование были включены 247 пациентов пожилого и старческого возраста (139 мужчин, 108 женщин, средний возраст - 74,1±6,3 года), госпитализированных с признаками ОНМК по ишемическому или геморрагическому типу. Согласно модели бинарной логистической регрессии, статистически значимо ассоциированы с развитием неблагоприятного исхода у изучаемой группы респондентов следующие параметры: возраст свыше 75 лет (p=0,011), степень инвалидизации по шкале mRS 3 (р=0,009), а также уровень С-РБ >100 мг/л (р=0,023) и мочевины >7 ммоль/л (р=0,044). Для снижения частоты встречаемости неблагоприятного клинического исхода у пациентов старшей возрастной группы с инсульт-ассоциированной нозокомиальной пневмонией необходимо верифицировать перечисленные выше клинико-лабораторные параметры на ранних этапах госпитализации. In the domestic and foreign specialized literature, there are no studies devoted to the study of risk factors of mortality in the older age patients with stroke-associated nosocomial pneumonia. The purpose of the study was to study the risk factors of adverse clinical outcomes in elderly and senile patients with stroke-associated nosocomial pneumonia. The study included 247 elderly and senile patients (139 men, 108 women, mean age - 74,1±6,3 years) who were hospitalized with signs of ischemic or hemorrhagic stroke. According to the binary logistic regression model, the following parameters are statistically significantly associated with adverse clinical outcomes in the studied group of respondents: age over 75 years (p=0.011), degree of disability according to mRS ≥3 (p=0,009), and C-reactive protein levels over 100 mg/l (p=0,023) and urea more than 7 mmol/l (p=0,044). In order to reduce the incidence of adverse clinical outcomes in patients of the older age group with stroke-associated nosocomial pneumonia, it is necessary to verify the above clinical and laboratory parameters at the early stages of hospitalization.


2018 ◽  
Vol 2 (suppl_1) ◽  
pp. 367-368
Author(s):  
D Kim ◽  
R J Glynn ◽  
J Avorn ◽  
L A Lipsitz ◽  
K Rockwood ◽  
...  

2020 ◽  
Author(s):  
Boyu Wu ◽  
Chengjie Xiong ◽  
Biwang Huang ◽  
Dongdong Zhao ◽  
Zhipeng Yao ◽  
...  

Abstract Background: Lateral recess stenosis (LRS) is a common degenerative disease in the elderly. Since the rise of comorbidity is associated with the increasing age, the percutaneous endoscopic lumbar decompression is advocated. The objective of this study was to compare the clinical outcomes of percutaneous endoscopic lumbar decompression in LRS via TESSYS or TESSYS-ISEE approach. Methods: A total of 45 and 42 consecutive patients with limp or radiculopathy symptoms underwent percutaneous endoscopic lumbar decompression using transforaminal endoscopic spine system (TESSYS) and TESSYS-ISEE, respectively. The radiation exposure and operation time, time to return to work, and complications were compared between two groups. Their clinical outcomes were evaluated with visual analogue scale (VAS) leg pain score, VAS back pain score, Oswestry Disability Index (ODI) and Modified MacNab’s criteria. Results: The average values of radiation exposure and operative time in TESSYS group were significantly higher than those in TESSYS-ISEE group (P<0.05). The postoperative VAS and ODI scores in both groups were significantly improved compared with before the operation (P<0.05). In addition, the VAS score of the leg and ODI score in the TESSYS-ISEE group were significantly lower than those in TESSYS group at 1 week follow-up (P<0.05). The good-to-excellent rates of the TESSYS and TESSYS-ISEE group were 88.89 and 90.48%, respectively, whereas the complication occurrence rates were 6.67 and 4.76% in TESSYS and TESSYS-ISEE groups, respectively. Conclusions: TESSYS-ISEE can be applied to treat LRS safely and effectively with short radiation exposure and operation time. This approach was comparable to the TESSYS approach with improved VAS leg pain and ODI score in short period after operation. However, potential complications and risks still needs to be considered.


Author(s):  
Shrirang Bhurchandi ◽  
Sachin Agrawal ◽  
Sunil Kumar ◽  
Sourya Acharya

Background: Ageing is a global fact affecting both developed and developing countries.It brings out various catabolic changes in body resulting in frailty(i.e. the person is not able to with stand minor stresses of the environment, due to reduced reserves in psychologicalreserve of several organ system).Thus causing a great burden of disease, dependence & health care cost. Sarcopenia is the leading component for frailty in the elderly population, but very few studies have been done in India for correlating frailty with sarcopenia. Aim: To compare sarcopenia with modified frailty index (MFI) as a predictor of adverse outcomes in critically ill elderly patients. Methodology: Cross-sectional study will be performed on all the critically ill geriatric subjects/patients coming to all the ICU's of AVBRH, Sawangi (M), Wardha who will satisfy various inclusion and exclusion criteria for selection and all standard parametric & non-parametric data will be assessed by using standard descriptive & inferential statistics. Expected Results: In our study, we are anticipating that the Modified frailty index to be a better predictor of adverse outcomes in terms of mortality as compared to sarcopenia in the critically ill elderly patients. Also, we are anticipating that sarcopenia to be the most important contributor of frailty in critically ill elderly patients and the prevalence of frailty will be high in critically ill elderly patients. Limitation: Due to limited time frame & resources we will not be able to follow up the patients.


Author(s):  
Eseohen Imoukhome ◽  
Lori E. Weeks ◽  
Samina Abidi

The objective of this article is to develop a validated mobile app prototype to empower the elderly and caregivers to manage falls that provides personalized and actionable educational materials at the point of care and improves the engagement of the elderly and caregiver in adopting validated fall management practices; To determine the usefulness and suitability of a fall management mobile app to the elderly and caregivers. The method used is a knowledge management approach is used to implement the app based on 2 validated models: Patient Health Engagement Model and Rockwood frailty index. A mixed method evaluation including a cognitive walk through is used to collect end-user feedback from the elderly and caregivers, on the usability, usefulness, and suitability of the app. The app was deemed easy to use, informative and understandable. Potential improvement areas include: larger print; less wordy interfaces; better navigation features; data sharing functionalities; and voice readers. These suggestions will be incorporated in the future. The conclusion of this article is that smartphones have vast potential in providing relevant and creditable fall management information to elderly and caregivers.


2012 ◽  
Vol 60 (17) ◽  
pp. B187
Author(s):  
Bruno Bernardi ◽  
Amanda Sousa ◽  
Ricardo Costa ◽  
Jose Costa ◽  
Galo Maldonado ◽  
...  

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