scholarly journals 481. SARS-CoV-2 Infection in Hospitalized Children: An Elevated Body Mass Index is a Marker of Increased Risk of Acute Respiratory Failure

2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S341-S342
Author(s):  
Catherine Foster ◽  
Shelley Kumar ◽  
Elizabeth Tocco ◽  
Galit Holzmann-Pazgal ◽  
Judith R Campbell ◽  
...  

Abstract Background Several risk factors are known to increase the severity of coronavirus disease 2019 (COVID-19) illness in adults, including age and obesity. Specific comorbidities affecting COVID-19 outcomes in children are less well defined. Methods We performed a retrospective cohort study of overweight and obese (OW) children compared to underweight and normal weight (NW) children with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Children between 2 and 18 years of age who were admitted to Texas Children’s Hospital from April through December of 2020 with a positive SARS-CoV-2 polymerase chain reaction test were included. Asymptomatic patients undergoing surveillance testing for SARS-CoV-2 were excluded. Body mass index (BMI) was calculated using the Centers for Disease Control definition. Demographic and clinical information was obtained from the electronic medical record. Statistical analyses were performed using SAS 9.0. Results We identified 145 total children who met inclusion criteria. Fifty-five (38%) children were NW and 90 (62%) children were OW. Demographics and characteristics are shown (Figure 1). Underlying asthma or chronic lung disease was present in 13 (24%) vs 31 (34%) in the NW and OW groups respectively (P=0.17). OW children were more likely to have pneumonia than NW children [relative risk1.6 (CI 1.40-2.45)]. An elevated BMI was also associated with an increased risk of requiring oxygen [relative risk 1.4 (CI 1.03-1.96)]. The median length of hospitalization was 4 days for NW versus 5 days for OW children (P=0.6). Admission to the Intensive Care Unit (ICU) was similar between the groups (P=0.7). There was no significant difference in treatments administered to children in the two groups, although there was a trend towards increased steroid (29 (53%) vs 59 (67%), P=0.13) and remdesivir (12 (22%) vs 30 (33%), P=0.14) use in the OW children. Four children in each group died. Characteristics of Hospitalized Children with SARS-CoV-2 Infection by Weight Category Abbreviations: ECMO, extracorporeal membrane oxygenation; ICU, intensive care unit; MIS-C, multisystem inflammatory syndrome in children; MV, mechanical ventilation; NC, nasal cannula *Denotes statistically significant P-value a. Calculated using chi-square or fisher exact unless otherwise noted. a. Calculated using chi-square or fisher exact unless otherwise noted. A P-value <0.05 was considered significant. b. Calculated using Wilcoxon rank sum test. c. Includes patients with home noninvasive MV (2) or tracheostomy and home MV(4). Conclusion For children admitted with symptomatic COVID-19, being overweight or obese was significantly associated with having pneumonia and with requiring oxygen. A difference in ICU admission, length of hospitalization, and mortality was not observed. Obesity prevention along with vaccination efforts may prevent COVID-19 related morbidity in this group. Disclosures All Authors: No reported disclosures

Biomedicine ◽  
2020 ◽  
Vol 39 (3) ◽  
pp. 480-483
Author(s):  
Monteiro Geraldin ◽  
N Anupama ◽  
Rekha D. Kini ◽  
Nayanatara A. K. ◽  
Sneha Shetty ◽  
...  

Introduction and Aim: Nutritional state of the mother before and during pregnancy is one of the important determinants along with factors like pre-pregnancy BMI, weight gain during pregnancy and gestational age which determines pregnancy outcome. Adequate gestational weight gain contributes for better pregnancy outcomes in both mother and infants for short- and long-term health. Materials and Methods: This is an observational study conducted retrospectively over a year comprised 300 pregnant subjects in their second trimester. Incidence of anemia, preterm labour, intrauterine growth retardation (IUGR) and neonatal intensive care unit (NICU) admission were compared in women with various Body Mass index (BMI). Analysis of the data was done using SPSS version 13 using chi square test and p ? 0.05 was considered statistically significant. Results: Out of 300 subjects, 79 developed anemia, among these 64(81%) were in the underweight category. 49 cases had a preterm delivery, out of these 49 cases, about 37(75.5%) belonged to the underweight BMI category. 39 cases delivered an intra-uterine growth retarded baby. Out of these 39 cases, about 25 (64.1%) belonged to the underweight BMI category. 56 neonates required intensive care unit (NICU) admission, of which 41 (73.2%) neonates born for underweight BMI mothers. Conclusion: The high proportions of underweight pregnancies in this study reflects the poor nutritional status. Adverse effects of maternal low body mass index target the fetus. Adequate weight gain of pregnant woman is an extremely important factor for the fetal outcome.  


2020 ◽  
Author(s):  
Ata Mahmoodpoor ◽  
Fahimeh Karrubi ◽  
Mohammad-Salar Hosseini ◽  
Afshin Iranpour ◽  
Sarvin Sanaie

Abstract Background: Obesity, a wide-ranging disorder all around the world, is associated with significant morbidity and mortality in the general population. Regarding the present controversies, this study aims to evaluate the possible association of body mass index (BMI) and mortality in patients admitted to intensive care units.Methods: During this cross-sectional study, all patients admitted to the intensive care unit of two university affiliated hospitals in northwest of Iran from November 2017 to March 2019 were enrolled. The demographic characteristics of patients, length of stay in the intensive care unit and hospital, organ failure, mortality, duration of mechanical ventilation and vasopressor-therapy, type of nutrition, the occurrence of nosocomial infection, type of admission (medical, surgical, trauma) were recorded for all patients. According to the WHO classification of BMI, patients were divided into the six groups, and the data were analyzed accordingly.Results: Of the 502 patients studied, 267 were male (53.2%) and 235 were female (46.8%). The highest mortality rate was observed among the obesity class II patients (35 < BMI < 40) with 28.6%, while the lowest rate was observed in the normal-weight patients (18.5 < BMI < 25) with 3.9%. The highest length of hospital stay was seen in patients with BMI > 30 with 12 days of hospitalizations. APACHE II and waist circumference had a statistically significant relationship with the mortality rate of patients (P-value < 0.001).Conclusion: The current study showed that BMI could be related to mortality, regardless of waist circumference and APACHE II score. However, considering waist circumference and APACHE II score as confounding factors, BMI does not have a significant effect on mortality and only affect the morbidity of patients.


2020 ◽  
Vol 34 (4) ◽  
pp. 361-366
Author(s):  
Edcleide Oliveira dos Santos Olinto ◽  
Gina Araújo Martins Feitosa ◽  
Izaura Odir Lima Gomes da Costa ◽  
Janine Maciel Barbosa ◽  
Ericka Vilar Bôtto Targino ◽  
...  

Introduction: There is a strong relationship between malnutrition and increased length of hospitalization and morbidity and mortality. Studies have shown that malnourished patients can have up to twenty times more complications than eutrophic ones. In critically ill patients, there is a tendency to catabolism, resulting in the loss of lean body mass, which when it reaches 40% is usually lethal. Methods: A quantitative, descriptive study was conducted on adults from both genders, admitted to the intensive care unit (ICU) of a university hospital, from March to December 2018. The following variables were collected from the evaluation and nutritional records: length of hospitalization in the ICU, date of discharge or death, nutritional risk through specific screening, height, weight and arm circumference (AC). For the screening, the Nutric score was used. For the nutritional evaluation, the body mass index (BMI) and AC indicators and the classifications recommended by the World Health Organization (2004) and Blackburn and Thornton (1979) were used. After collecting the data, they were analyzed in the Statistical Package for Social Sciences (SPSS) 13.0 and for the association of the variables the Chi-square test was used, considering statistical difference when the p value <0.05. Results: The sample consisted of 116 patients, mostly female (53.4%) whose median age was 46 years (interquartile range IQR 31-53). Regarding the frequency of nutritional risk, most patients (61.5%) had a low score. There was an important frequency of malnutrition, according to the AC indicator (73%), although BMI (43.5%) showed eutrophy. Even though most patients had low nutritional risk, those with high nutritional risk (38.5%) had a higher tendency to mortality, however, not statistically confirmed (p> 0.05). There was also a tendency of association between death and malnutrition, although no statistical significance was shown(p> 0.05). Conclusion: Patients at nutritional risk and/or malnutrition appear to be vulnerable to worse clinical outcomes.


2010 ◽  
Vol 38 (5) ◽  
pp. 1308-1314 ◽  
Author(s):  
Jean-Baptiste M. Paolini ◽  
Julien Mancini ◽  
Michèle Genestal ◽  
Hélène Gonzalez ◽  
Rachel Eshima McKay ◽  
...  

2020 ◽  
Vol 20 (3) ◽  
Author(s):  
Cici Enjelia Nata ◽  
Safrizal Rahman ◽  
Sakdiah Sakdiah

Abstrak. Indeks Massa Tubuh (IMT) merupakan parameter yang digunakan untuk menilai komposisi tubuh dengan menggunakan klasifikasi Asia Pasifik. IMT menjadi salah satu faktor risiko terjadinya osteoartritis lutut. Osteoartritis lutut merupakan penyakit degeneratif yang terjadi pada sendi lutut. Berdasarkan RISKESDAS tahun 2018, Provinsi Aceh menduduki peringkat pertama sebagai provinsi dengan angka penyakit sendi terbanyak yang termasuk osteoartritis lutut yaitu 13.3%. Prevalensi indeks massa tubuh berlebih di Indonesia pada tahun 2018  meningkat dari 26.3% menjadi 34.4% sehingga kemungkinan terjadinya osteoartritis lutut juga meningkat. Penelitian ini menggunakan metode observasional analitik dengan desain cross-sectional dilakukan dengan cara mengukur berat badan dan tinggi badan responden yang memenuhi kriteria penelitian berdasarkan pedoman American College of Rheumatology (ACR). Sampel dikumpulkan berdasarkan rekam medis di Rumah Sakit Umum Zainoel Abidin kota Banda Aceh sejak september hingga oktober 2019 yang melibatkan tujuh puluh responden sebagai sampel penelitian yang dimana 51 responden (72.9%) memiliki indeks massa tubuh berlebih dan 43 responden (61.4%) didiagnosis dengan Osteoartritis lutut. Berdasarkan hasil analisis uji Chi Square, nilai p value yang diperoleh adalah 0.021 (p value ≤ 0,05). Dengan demikian, penelitian ini menunjukkan bahwa terdapat hubungan antara indeks massa tubuh dengan kejadian osteoartritis lutut di Rumah Sakit Umum Zainoel Abidin di kota Banda Aceh.Kata Kunci: Indeks massa tubuh; berat badan lebih, osteoartritis lutut;               Abstract. Body Mass Index (BMI) is a parameter to measure body composition which is classified into underweight, normal and overweight. Overweight has been known to potentially cause knee osteoarthritis. Knee osteoarthritis is a degenerative disease happening on the knee. Based on RISKESDAS 2018, Aceh led Indonesia as a province with the highest number of knee arthritis (13.3%). In the same year, the prevalence of overweight in Indonesia has also increased from 26.3% to 34.4% and is expected to rise annually. This research is an analytic observational using cross sectional design. The method used in this research is body weight and body length measurement of samples fulfilling the criteria based on American College of Rheumatology (ACR). Data were collected based on medicalr record at Zainoel Abidin General Hospital, Banda Aceh, from September to October 2019. We examined 70 respondents, 51 of them (72.9%) had overweight IMT and 43 of them (61.4%) were diagnosed with knee osteoarthritis. Chi Square analysis showed p value 0,021 (p value ≤ 0.05). We concluded that there is a correlation between body mass index with knee osteoarthritis in Zainoel Abidin General Hospital, Banda Aceh.Keyword: Body Mass Index; overweight; knee osteoarthritis;


2021 ◽  
Vol 1 (2) ◽  
pp. 52-58
Author(s):  
Devi ◽  
Bambang S ◽  
Sumedi W

Introduction: Dietary factors or eating patterns can cause patients to experience anorexia so that it affects the body mass index measured by CKD patients (Susetyowati, 2014). Therefore, it is important to understand the research when studying the relationship between the diet of CKD patients and the body mass index of patients undergoing hemodialysis at the Dik Pusdikkes Hospital in 2021. Objective: This study aims to determine how big the influence of the relationship between the diet of CKD patients and the body mass index of patients undergoing hemodialysis to improve the quality of life of CKD patients. Method: The type of research used is quantitative research with a correlational design to determine whether there is a relationship between variables using experimental research. The population in this study that became the study population were all hemodialysis patients at the AD Pusdikkes Hospital. The sampling technique used was total sampling. The research instrument used is a questionnaire. The questionnaire is not standardized so that validity and reliability tests are carried out. In this study, the analysis used the chi-square test. Results: the results of the chi-square test showed that the p-value (0.028) <0.05 then Ha was accepted or there was a relationship between the diet of CKD patients and the patient's body mass index. Conclusion: Based on the results of the analysis of the relationship between the evaluation of hemodialysis patients at RS Dik Pusdikkes Kodiklat AD, 9 respondents had a poor diet with a body mass index in the lean category of 6 people (66.7%) and the normal category of 3 people (33.3%). And 11 respondents have a good diet relationship with body mass index in the thin category of 2 people (40.0%) and the normal category of 12 people (60%).


2021 ◽  
Vol 1 (1) ◽  
pp. 103-114
Author(s):  
Rilyani Rilyani ◽  
Lidya Aryanti ◽  
Calvyn Reza Trisnantyas

ABSTRACT: EMPLOYMENT RELATIONSHIP AND WORKING SCHEDULE WITH BODY MASS INDEX IN YOSODADI PUSKESMAS WORKING AREA METRO CITY Introduction: The coverage of children under five in Lampung Province in 2019 was 79%, and this figure was above the target (76.18%). This figure illustrates that participation from the community to come to posyandu is still quite good in Lampung Province, while for Metro City the percentage of data is weighted at 78.8%. Data obtained through the Metro City Health Office in 2020 at the Yosodadi Health Center obtained as many as 656 toddlers aged 1-5 years who were weighingObjective: To find out the relationship between work and work schedule with the body mass index of toddlers aged 1-5 years.Methods: This type of research is quantitative. The design in this study uses an analytical survey design with a cross-sectional approach. The population is mothers and children aged 3-5 years, which is then calculated using the Slovin formula to obtain 197 children. Sampling technique purposive sampling Analysis of univariate and bivariate data using the chi-square test.Results: working mothers as many as 107 respondents (54.3%)., standard work schedule is 8 hours per day as many as 109 respondents (55.3%), BMI is not ideal, namely < 18.5 and > 22.9 as many as 103 respondents ( 52.3%. The results of statistical tests using the chi-square test obtained p-value = 0.000 (<α0.05), p-value = 0.085 (>α0.05).Conclusion: The results of statistical tests using the chi-square test obtained p-value = 0.000 (<α0.05) which means the relationship between mother's work and body mass index of toddlers aged 3-5. The p-value = 0.085 (>α0.05) means that there is no relationship between the mother's work schedule and the body mass index of children aged 3-5 years. It is recommended that parents who have toddlers with underweight and obese nutritional status should pay more attention to parenting patterns Keywords            :  Mother's Work Work Schedule, Toddler Body Mass Index  INTISARI: HUBUNGAN PEKERJAAN DAN JADWAL KERJA DENGAN INDEKS MASSA TUBUH BALITA DI WILAYAH KERJA PUSKESMAS YOSODADI KOTA METRO   Pendahuluan: Cakupan balita ditimbang di Provinsi lampung tahun 2019 sebesar 79 %, dimana angka ini diatas target (76,18%). Angka ini menggambarkan bahwa partisipasi dari masyarakat untuk datang ke posyandu masih cukup baik di Provinsi Lampung, sedangkan untuk Kota Metro persentase data ditimbang sebesar 78,8%. Data yang diperoleh melalui Dinkes Kota Metro tahun 2020 di Puskesmas Yosodadi didapat sebanyak 656 balita usia 1-5 tahun yang melakukan penimbangan berat badanTujuan: Diketahui hubungan pekerjaan dan jadwal kerja dengan  indeks massa tubuh balita usia 1-5 tahun.Metode: Jenis penelitian kuantitatif, Rancangan dalam penelitian ini menggunakan desain Survei Analitik dengan pendekatan cross sectional. Populasi adalah  ibu dan anak usia 3-5 tahun, yang kemudian dilakukan perhitungan sampel dengan rumus slovin didapat sebanyak 197 anak. Teknik sampling purposive sampling Analisa data univariat dan bivariat  menggunakan uji chi square.Hasil : ibu bekerja sebanyak 107 responden (54,3%)., jadwal kerja standar yaitu 8 jam per hari sebanyak 109 responden (55,3%), IMT tidak ideal yaitu < 18,5 dan > 22,9 sebanyak 103 responden (52,3%). Hasil uji statistik menggunakan uji chi square didapat nilai p-value = 0.000 (<α0.05), nilai p-value = 0.085 (>α0.05).Kesimpulan : Hasil uji statistik menggunakan uji chi square didapat nilai p-value = 0.000 (<α0.05) yang artinya ada hubungan pekerjaan ibu dengan  indeks massa tubuh balita usia 3-5. Nilai p-value = 0.085 (>α0.05) yang artinya tidak ada hubungan jadwal kerja ibu dengan  indeks massa tubuh balita usia 3-5 tahun. Disarankan kepada orang tua yang memiliki balita dengan status gizi kurus dan gemuk, harus lebih memperhatikan lagi mengenai pola asuh anak           Kata Kunci      : Pekerjaan Ibu Jadwal Kerja, Indeks Masa Tubuh Balita 


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