Prognostic factors for finger interphalangeal joint osteoarthritis: a systematic review

Abstract Objective Radiographic hand OA affects one in five adults. Symptomatic hand OA can result in functional impairment, pain and reduced quality of life. A prevalent form of hand OA is IP joint OA, however prognostic factors for IP joint OA remain poorly understood. This systematic review aimed to identify prognostic factors for IP joint OA, and to summarize the diagnostic criteria for IP joint OA in prognostic studies. Methods EMBASE, MEDLINE, Scopus and The Cochrane Library were searched from inception until 19 February 2020 (PROSPERO CRD42019116782). Eligible studies described diagnostic criteria defining IP joint OA, and assessed potential prognostic factors for IP joint OA. Risk of bias was assessed using a modified Quality in Prognosis Studies (QUIPS) tool and a best evidence synthesis was used. Results Eighteen studies were included (risk of bias: eight high, three moderate, seven low). All defined OA radiographically, and three studies incorporated clinical symptoms into their definition of OA. Forty-nine potential prognostic factors were assessed. Eight were prognostic: older age in women, female gender (both moderate evidence); family history of Heberden’s nodes, Kashin–Beck disease, older age in men, dental occupation in men, finger fracture, parity (all limited evidence). Higher BMI in women (limited evidence) was prognostic for symptomatic radiographic OA. No prognostic factors for symptomatic OA were identified. Conclusion IP joint OA is most commonly defined radiographically, yet criteria were heterogeneous. Eight prognostic factors for radiographic IP joint OA and one for symptomatic radiographic IP joint OA were identified, all with limited or moderate evidence. Further studies on causality and on prognostic pathways are needed.

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A Multivariable Prediction Model for the Chronification of Non-traumatic Shoulder Pain: A Systematic Review

January 2018 - Pain Physician ◽

10.36076/ppj/2016.19.1 ◽

2016 ◽

Vol 19 (2;2) ◽

pp. 1-10 ◽

Cited By ~ 13

Author(s):

Filip Struyf

Keyword(s):

Systematic Review ◽

Prognostic Factors ◽

Shoulder Pain ◽

Evidence Synthesis ◽

Complete Recovery ◽

International Classification Of Functioning ◽

Large Variability ◽

Poor General Health ◽

Moderate Evidence ◽

Best Evidence Synthesis

Background: Shoulder pain is the third most common musculoskeletal complaint and many patients have an unfavorable outcome with long-term disability. Only 50% of all new episodes of shoulder pain show complete recovery within 6 months. Little is known about factors that contribute to chronicity of shoulder pain, although such information is needed for the management of patients with acute and sub-acute shoulder pain. Objective: To systematically review the literature for prognostic factors which are potential predictors for either recovery or chronification in patients with acute and sub-acute nontraumatic shoulder pain. Study Design: Systematic review. Setting: This systematic review examined all studies involving the prognosis of shoulder pain patients. Methods: This systematic review was reported following the guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Two reviewers independently scored the methodological quality of the selected studies. Due to heterogeneity of studies, a best-evidence synthesis of the available prognostic factors was provided. Results: Nine studies met our inclusion criteria and were included in this systematic review. There is strong evidence that high scores on the Shoulder Pain and Disability Index (SPADI), high scores on shoulder pain severity, and a long duration of complaints are factors that contribute to the chronification of shoulder pain. Moderate evidence was found supportive for other prognostic factors that enhance chronification, like being male, being over 55 years of age, having poor general health, having a gradual onset of complaints, a large amount of sick leave, the perception of high job demand, the perception of low social support, and the amount of visits to a health care professional. Also moderate evidence exists regarding factors that contributed to a reduced possibility of chronification: an active treatment policy and not taking medication on regular basis. Limitations: The large variability in definitions of shoulder pain, and patient selection bias. In addition, there is a paucity of strong longitudinal prospective studies. Conclusion: This systematic review found evidence that high scores on the SPADI questionnaire, more shoulder pain, and a longer duration of complaints are associated with chronification of shoulder pain. In order to reduce chronification, clinicians can use the International Classification of Functioning based model presented here that could aid their decision-making. Key words: Shoulder pain, prognostic factors, systematic review, prognosis, assessment

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Prognostic Factors to Determine Survivorship of Meniscal Allograft Transplant: A Systematic Review

Orthopaedic Journal of Sports Medicine ◽

10.1177/23259671211007215 ◽

2021 ◽

Vol 9 (6) ◽

pp. 232596712110072

Author(s):

Ding-yu Wang ◽

Cassandra A. Lee ◽

Yan-zhang Li ◽

Bo Zhang ◽

Nan Li ◽

...

Keyword(s):

Systematic Review ◽

Prognostic Factors ◽

Acl Reconstruction ◽

Strong Evidence ◽

Evidence Synthesis ◽

Cartilage Damage ◽

Older Age ◽

Cochrane Central Register ◽

Meniscal Allograft ◽

Best Evidence Synthesis

Background: There is much room for improvement and optimization of meniscal allograft survivorship. Purpose: To understand prognostic factors for survivorship using evidence-based selection criteria in order to identify patients who would best benefit from meniscal allograft transplant (MAT). Study Design: Systematic review; Level of evidence, 4. Methods: We conducted this systematic review to analyze prognostic factors for survivorship of MAT. The Cochrane Central Register, PubMed publisher, Embase.com , and Web of Science databases were searched through August 8, 2019. Included studies entailed patients of any age who received MAT with a reported association between prognostic factors and survivorship of the allograft. Two reviewers independently screened all titles and abstracts for eligibility, extracted the data, assessed the risk of bias using the Newcastle-Ottawa Scale, and performed a best-evidence synthesis. Results: The review included 18 studies with a total of 1920 patients. The mean follow-up time was 6.0 years (range, 2.1-11.2 years). A total of 20 prognostic factors were identified and shown to be associated with survivorship of MAT. Strong evidence was found that severe cartilage damage was associated with poor survivorship. Strong evidence was also found showing that sex, knee compartment, surgical side, concomitant anterior cruciate ligament (ACL) reconstruction, and concomitant osteotomy for malalignment had no effect on survivorship. Moderate evidence was found that body mass index (<36), tobacco use, and arthroscopic versus open procedure had no influence on survivorship. Conflicting evidence was found that older age and kissing cartilage lesions (lesions on both the femur and tibia vs on a single side) decreased survivorship. Conclusion: Severe cartilage damage decreases the survivorship of MAT. Concomitant ACL reconstruction and osteotomy showed no relationship to survivorship. Many determinants showed conflicting and limited evidence. Older age may be of interest and should be further studied.

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Is acupuncture effective for knee osteoarthritis? A protocol for a systematic review and meta-analysis

BMJ Open ◽

10.1136/bmjopen-2021-052270 ◽

2022 ◽

Vol 12 (1) ◽

pp. e052270

Author(s):

Chuan-Yang Liu ◽

Jian-Feng Tu ◽

Myeong Soo Lee ◽

Ling-Yu Qi ◽

Fang-Ting Yu ◽

...

Keyword(s):

Systematic Review ◽

Knee Osteoarthritis ◽

Evidence Synthesis ◽

Meta Analysis ◽

Demographic Data ◽

Risk Of Bias ◽

Biomedical Literature ◽

Cochrane Library ◽

China National Knowledge Infrastructure ◽

Best Evidence Synthesis

IntroductionKnee osteoarthritis (KOA) is one of the leading causes of disability. The effectiveness of acupuncture for treating KOA remains controversial. This protocol describes the method of a systematic review and meta-analysis evaluating the effectiveness and safety of acupuncture for treating KOA.Methods and analysisFour English databases (PubMed, Embase, Cochrane Library databases and Web of Science) and four Chinese databases (China National Knowledge Infrastructure, Chinese Biomedical Literature Database, VIP Database for Chinese Technical Periodicals, and Wanfang) will be searched from the database inception to 1 September 2021. All randomised controlled trials related to acupuncture for KOA will be included. Extracted data will include publication details, basic information, demographic data, intervention details and patient outcomes. The primary outcome will be pain intensity. Risk of bias will be assessed using the Cochrane Collaboration’s tool for assessing risk of bias. Article selection, data extraction and risk of bias assessment will be performed in duplicate by two independent reviewers. If the meta-analysis is precluded, we will conduct a descriptive synthesis using a best-evidence synthesis approach. The strength of recommendations and quality of evidence will be assessed using the Grading of Recommendations Assessment Development and Evaluation working group methodology.Ethics and disseminationEthics approval is not required because individual patient data are not included. This protocol was registered in the international Prospective Register of Systematic Reviews on 25 February 2021. The systematic review and meta-analysis will be submitted for publication in a peer-reviewed journal. The findings will also be disseminated through conference presentations.Trial registration numberCRD42021232177.

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Topical glyceryl trinitrate for the treatment of tendinopathies: a systematic review

British Journal of Sports Medicine ◽

10.1136/bjsports-2018-099552 ◽

2018 ◽

Vol 53 (4) ◽

pp. 251-262 ◽

Cited By ~ 9

Author(s):

Dimitris Challoumas ◽

Paul D Kirwan ◽

Dmytro Borysov ◽

Christopher Clifford ◽

Michael McLean ◽

...

Keyword(s):

Systematic Review ◽

Glyceryl Trinitrate ◽

Strong Evidence ◽

Evidence Synthesis ◽

Clinical Effects ◽

Range Of Movement ◽

Level Of Evidence ◽

Moderate Evidence ◽

Best Evidence Synthesis ◽

Topical Glyceryl Trinitrate

ObjectiveTo produce a best evidence synthesis of the clinical effects of topical glyceryl trinitrate (GTN) in the treatment of tendinopathies.DesignA systematic review of published randomised controlled trials (RCTs) of the use of GTN in patients with tendinopathy.Data sourcesMEDLINE, Embase, Scopus and CINAHL from database inception to January 2018.MethodsWe examined RCTs comparing the effects of topical GTN with either placebo or other treatments on tendinopathy. Overall quality of each eligible study was determined based on a combined assessment of internal validity, external validity and precision. The level of evidence for each assessed parameter was rated based on the system by van Tulderet al.ResultsA total of 10 eligible RCTs were identified including patients with tendinopathy of the rotator cuff (n=4), wrist extensors (n=3), Achilles (n=2) and patellar (n=1) tendons. For all tendinopathies, improvements in pain were significant when comparing GTN versus placebo in the short term (<8 weeks; poor evidence). Significant improvements in midterm outcomes for treatment with GTN versus placebo included the following: patient satisfaction (strong evidence); chances of being asymptomatic with activities of daily living (strong evidence); range of movement (moderate evidence); strength (moderate evidence); pain (at night and with activity; poor evidence) and local tenderness (poor evidence). Patients treated with topical GTN reported a higher incidence of headaches than those who received placebo (moderate evidence).Conclusions and relevanceTreatment of tendinopathies with topical GTN for up to 6 months appears to be superior to placebo and may therefore be a useful adjunct to the treating healthcare professions.

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Risk factors for, and prevention of, shoulder injuries in overhead sports: a systematic review with best-evidence synthesis

British Journal of Sports Medicine ◽

10.1136/bjsports-2017-098254 ◽

2018 ◽

Vol 52 (20) ◽

pp. 1312-1319 ◽

Cited By ~ 23

Author(s):

Martin Asker ◽

Hannah L Brooke ◽

Markus Waldén ◽

Ulrika Tranaeus ◽

Fredrik Johansson ◽

...

Keyword(s):

Risk Factors ◽

Systematic Review ◽

Injury Prevention ◽

Evidence Synthesis ◽

Shoulder Injuries ◽

Prevention Measures ◽

Shoulder Injury ◽

Limited Evidence ◽

Best Evidence Synthesis ◽

Overhead Sports

ObjectiveTo assess the evidence for risk factors and prevention measures for shoulder injuries in overhead sports.DesignSystematic review with best-evidence synthesis.Data sourcesMedline (Ovid), PubMed (complementary search), Embase (Elsevier), Cochrane (Wiley), SPORTDiscus (Ebsco) and Web of Science Core Collection (Thomson Reuters), from 1 January 1990 to 15 May 2017.Eligibility criteria for selecting studiesRandomised controlled trials, cohort studies and case-control studies on risk factors or prevention measures for shoulder injuries in overhead sports. The eligible studies were quality assessed using the Scottish Intercollegiate Guidelines Network criteria.ResultsOf 4778 studies identified, 38 were eligible for quality review and 17 met the quality criteria to be included in the evidence synthesis. One additional quality study presented a shoulder injury prevention programme. Most studies focused on baseball, lacrosse or volleyball (n=13). The risk factors examined included participation level (competition vs training) (n=10), sex (n=4), biomechanics (n=2) and external workload (n=2). The evidence for all risk factors was limited or conflicting. The effect of the prevention programme within the subgroup of uninjured players at baseline was modest and possibly lacked statistical power.ConclusionsAll investigated potential risk factors for shoulder injury in overhead sports had limited evidence, and most were non-modifiable (eg, sex). There is also limited evidence for the effect of shoulder injury prevention measures in overhead sports.PROSPERO trial registration numberCRD42015026850.

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Recalibrating the risk of hamstring strain injury (HSI): A 2020 systematic review and meta-analysis of risk factors for index and recurrent hamstring strain injury in sport

British Journal of Sports Medicine ◽

10.1136/bjsports-2019-100983 ◽

2020 ◽

Vol 54 (18) ◽

pp. 1081-1088 ◽

Cited By ~ 7

Author(s):

Brady Green ◽

Matthew N Bourne ◽

Nicol van Dyk ◽

Tania Pizzari

Keyword(s):

Risk Factors ◽

Systematic Review ◽

Evidence Synthesis ◽

Meta Analysis ◽

Significant Risk ◽

Older Age ◽

Future Research ◽

Hamstring Strain ◽

Best Evidence Synthesis ◽

History Of

ObjectiveTo systematically review risk factors for hamstring strain injury (HSI).DesignSystematic review update.Data sourcesDatabase searches: (1) inception to 2011 (original), and (2) 2011 to December 2018 (update). Citation tracking, manual reference and ahead of press searches.Eligibility criteria for selecting studiesStudies presenting prospective data evaluating factors associated with the risk of index and/or recurrent HSI.MethodSearch result screening and risk of bias assessment. A best evidence synthesis for each factor and meta-analysis, where possible, to determine the association with risk of HSI.ResultsThe 78 studies captured 8,319 total HSIs, including 967 recurrences, in 71,324 athletes. Older age (standardised mean difference=1.6, p=0.002), any history of HSI (risk ratio (RR)=2.7, p<0.001), a recent HSI (RR=4.8, p<0.001), previous anterior cruciate ligament (ACL) injury (RR=1.7, p=0.002) and previous calf strain injury (RR=1.5, p<0.001) were significant risk factors for HSI. From the best evidence synthesis, factors relating to sports performance and match play, running and hamstring strength were most consistently associated with HSI risk. The risk of recurrent HSI is best evaluated using clinical data and not the MRI characteristics of the index injury.Summary/conclusionOlder age and a history of HSI are the strongest risk factors for HSI. Future research may be directed towards exploring the interaction of risk factors and how these relationships fluctuate over time given the occurrence of index and recurrent HSI in sport is multifactorial.

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An Overview of Strategies for Reducing Upper Extremity Physical Exposure Associated With Floor Mopping: A Systematic Review

Human Factors The Journal of the Human Factors and Ergonomics Society ◽

10.1177/0018720818816261 ◽

2018 ◽

Vol 61 (1) ◽

pp. 43-63 ◽

Cited By ~ 1

Author(s):

Mari-Anne Wallius ◽

Susanna Järvelin-Pasanen ◽

Saara M. Rissanen ◽

Pasi A. Karjalainen ◽

Kimmo Räsänen

Keyword(s):

Systematic Review ◽

Upper Extremity ◽

Evidence Synthesis ◽

Levels Of Evidence ◽

Moderate Evidence ◽

Positive Effects ◽

Physical Exposure ◽

Manual Search ◽

Best Evidence Synthesis ◽

The Impact

Objective: This systematic review synthesizes literature on upper extremity physical exposure associated with floor mopping, in order to (a) assess the impact of changes in mopping systems on physical exposure and (b) propose recommendations for strategies to reduce exposure. Background: Floor-cleaning tools and equipment have undergone major improvements. Existing studies have focused on mop design modifications and cleaning efficiency. However, less is known about strain responses caused by modern tools and methods. Method: Studies from 1987 to February 2017 were identified by electronic and manual search. All selected studies underwent a quality assessment. The evidence was organized into categories representing different strategies for reducing exposure. The levels of evidence were determined using a best evidence synthesis approach. Results: Eleven studies were included. Based on the review findings, currently there is moderate evidence suggesting that reduced physical exposure has been achieved through development of mopping systems. Levels of evidence for strategies associated with positive effects on physical exposure were: moderate evidence for mop design and handle type, insufficient evidence for mopping technique, and mixed evidence for mopping methods and environment modifications. Therefore, the present study suggests the use of adjustable mop handles as a strategy for reducing physical exposure. Conclusion: A more comprehensive approach to reducing physical exposure concerning floor mopping work is necessary. Application: Knowledge regarding physical exposure reduction can be applied as the basis for decision making in cleaning practice. Information can be incorporated into future research regarding development of floor-cleaning methods.

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Pain Trajectories in Knee Osteoarthritis—A Systematic Review and Best Evidence Synthesis on Pain Predictors

Journal of Clinical Medicine ◽

10.3390/jcm9092828 ◽

2020 ◽

Vol 9 (9) ◽

pp. 2828

Author(s):

Davide Previtali ◽

Luca Andriolo ◽

Giorgio Di Laura Frattura ◽

Angelo Boffa ◽

Christian Candrian ◽

...

Keyword(s):

Systematic Review ◽

Knee Osteoarthritis ◽

Evidence Synthesis ◽

Grey Literature ◽

Cochrane Library ◽

Related Factors ◽

Knee Oa ◽

Experienced Pain ◽

Best Evidence Synthesis ◽

Pain Trajectories

Different profiles of pain progression have been reported in patients with knee osteoarthritis (OA), but the determinants of this heterogeneity are still to be sought. The aim of this systematic review was to analyze all studies providing information about knee OA pain trajectories to delineate, according to patients’ characteristics, an evidence-based evolution pattern of this disabling disease, which is key for a more personalized and effective management of knee OA. A literature search was performed on PubMed, Web of Science, Cochrane Library, and grey literature databases. The Cochrane Collaboration’s tool for assessing risk of bias was used, and a best-evidence synthesis was performed to define the predictors of pain evolution. Seven articles on 7747 patients affected by knee OA (mainly early/moderate) were included. Daily knee OA pain trajectories were unstable in almost half of the patients. In the mid-term, knee OA had a steady pain trajectory in 85% of the patients, 8% experienced pain reduction, while 7% experienced pain worsening. Low education, comorbidities, and depression were patient-related predictors of severe/worsening knee OA pain. Conversely, age, alcohol, smoking, pain coping strategies, and medications were unrelated to pain evolution. Conflicting/no evidence was found for all joint-related factors, such as baseline radiographic severity.

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Is adiposity associated with back and lower limb pain? A systematic review

PLoS ONE ◽

10.1371/journal.pone.0256720 ◽

2021 ◽

Vol 16 (9) ◽

pp. e0256720

Author(s):

Waruna L. Peiris ◽

Flavia M. Cicuttini ◽

Sultana Monira Hussain ◽

Mahnuma M. Estee ◽

Lorena Romero ◽

...

Keyword(s):

Systematic Review ◽

Musculoskeletal Pain ◽

Lower Limb ◽

Evidence Synthesis ◽

Risk Of Bias ◽

Low Back ◽

Foot Pain ◽

Limb Pain ◽

Lower Limb Pain ◽

Best Evidence Synthesis

Background Back and lower limb pain have a major impact on physical function and quality of life. While obesity is a modifiable risk factor for musculoskeletal pain, the role of adiposity is less clear. This systematic review aimed to examine the relationship between both adiposity and its distribution and back and lower limb pain. Methods A systematic search of electronic databases was conducted to identify studies that examined the association between anthropometric and/or direct measures of adiposity and site specific musculoskeletal pain. Risk of bias was assessed and a best evidence synthesis was performed. Results A total of 56 studies were identified which examined 4 pain regions, including the lower back (36 studies), hip (two studies), knee (13 studies) and foot (eight studies). 31(55%) studies were assessed as having low to moderate risk of bias. 17(30%) studies were cohort in design. The best evidence synthesis provided evidence of a relationship between central adiposity and low back and knee pain, but not hip or foot pain. There was also evidence of a longitudinal relationship between adiposity and the presence of back, knee and foot pain, as well as incident and increasing foot pain. Conclusions This systematic review provides evidence of an association between both body fat and its central distribution and low back and knee pain, and a longitudinal relationship between adiposity and back, knee and foot pain. These results highlight the potential for targeting adiposity in the development of novel treatments at these sites.

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Risk factors for the progression of finger interphalangeal joint osteoarthritis: a systematic review

Rheumatology International ◽

10.1007/s00296-020-04687-1 ◽

2020 ◽

Vol 40 (11) ◽

pp. 1781-1792 ◽

Cited By ~ 2

Author(s):

Karishma Shah ◽

Xiaotian Yang ◽

Jennifer C. E. Lane ◽

Gary S. Collins ◽

Nigel K. Arden ◽

...

Keyword(s):

Risk Factors ◽

Potential Risk ◽

Evidence Synthesis ◽

Interphalangeal Joint ◽

Cochrane Library ◽

Limited Evidence ◽

Best Evidence Synthesis ◽

Patients With Diabetes ◽

Potential Risk Factors ◽

Osteoarthritis Progression

Abstract Progressive hand interphalangeal joint (IPJ) osteoarthritis is associated with pain, reduced function and impaired quality of life. However, the evidence surrounding risk factors for IPJ osteoarthritis progression is unclear. Identifying risk factors for IPJ osteoarthritis progression may inform preventative strategies and early interventions to improve long-term outcomes for individuals at risk of IPJ osteoarthritis progression. The objectives of the study were to describe methods used to measure the progression of IPJ osteoarthritis and identify risk factors for IPJ osteoarthritis progression. MEDLINE, EMBASE, Scopus, and The Cochrane Library were searched from inception to 19th February 2020 (PROSPERO CRD42019121034). Eligible studies assessed potential risk factor/s associated with IPJ osteoarthritis progression. Risk of bias was assessed using a modified QUIPS Tool, and a best evidence synthesis was performed. Of eight eligible studies, all measured osteoarthritis progression radiographically, and none considered symptoms. Eighteen potential risk factors were assessed. Diabetes (adjusted mean difference between 2.06 and 7.78), and larger finger epiphyseal index in males (regression coefficient β = 0.202) and females (β = 0.325) were identified as risk factors (limited evidence). Older age in men and women showed mixed results; 13 variables were not risk factors (all limited evidence). Patients with diabetes and larger finger epiphyseal index might be at higher risk of radiographic IPJ osteoarthritis progression, though evidence is limited and studies are biased. Studies assessing symptomatic IPJ osteoarthritis progression are lacking.

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