scholarly journals The time is now: a call for action to translate recent momentum on tackling tropical snakebite into sustained benefit for victims

2019 ◽  
Vol 113 (12) ◽  
pp. 835-838 ◽  
Author(s):  
Robert A Harrison ◽  
Nicholas R Casewell ◽  
Stuart A Ainsworth ◽  
David G Lalloo

Abstract Like the other WHO-listed Neglected Tropical Diseases (NTDs), snakebite primarily affects rural, impoverished tropical communities that lack adequate health resources. The annual 138 000 deaths and 400 000 disabilities suffered by these subsistence farming communities means that snakebite is an additional cause and consequence of tropical poverty. Unlike most of the NTDs, however, snakebite is a medical emergency, and requires rapid treatment in a hospital equipped with effective antivenom, beds and appropriately trained staff. The lack of such facilities in the remote areas most affected by snakebite, and the high treatment costs, explains why most victims, particularly in sub-Saharan Africa, consult traditional healers rather than seek hospital care. Whilst affordable, there is no evidence that traditional treatments are effective. The number of snakebite victims that die, unregistered, in the community is threefold higher than hospital-recorded deaths. After decades of inertia, WHO benefitted from advocacy interventions and the support of key agencies, including Médecins Sans Frontières, the Wellcome Trust, the Kofi Annan Foundation and the Global Snakebite Initiative, to recently institute transformative actions for reducing the public health burden of tropical snakebite. It is imperative that WHO and the other stakeholders now gain the support and investment of governments, research funders and donor agencies to ensure that this recent momentum for change is translated into sustained benefit to snakebite victims.

Author(s):  
Mavhungu Abel Mafukata

Since Sub-Saharan Africa's first independence in Ghana, the region has experienced massive and costly political and bureaucratic corruption within public service and administration. The causes of the corruption, its nature and form are wide and intertwined. In Sub-Saharan Africa, efforts to curb corruption have failed to discard it. The paper focused on the period from Nkruma in Ghana to Mutharika the 2nd in Malawi. This paper reviewed existing literature on political and bureaucratic corruption in Sub-Saharan Africa while on the other hand the paper employed key informant interviews to gather the required data to investigate, analyse and profile the genesis and evolution of corruption in Sub-Saharan Africa. The key informant interviews were employed to solicit public views and opinion from nineteen key informant participants (n=19) selected from 11 countries in Sub-Saharan Africa. The paper found that corruption is legendary; has entrenched itself to becoming some sort of culture in the region, and has become the most difficult socio-economic challenge to resolve in the region despite the various anti-corruption efforts employed by stakeholders to curb it. It emerged through the study that law-enforcement efforts against corruption need some reinforcement in order to be effective and eficient in uprooting corruption in the region. If Sub-Saharan Africa fails to address its corruption challenge, its development prospects would seriously curtailed.


2019 ◽  
Vol 34 (Supplement_1) ◽  
pp. S40-S45 ◽  
Author(s):  
Boris Gershman ◽  
Diego Rivera

Abstract This paper compares two approaches to measuring subnational ethnolinguistic diversity in Sub-Saharan Africa, one based on censuses and large-scale population surveys and the other relying on the use of geographic information systems (GIS). The two approaches yield sets of regional fractionalization indices that show a moderately positive correlation, with a stronger association across rural areas. These differences matter for empirical analysis: in a common sample of regions, survey-based indices of deep-rooted diversity show a more strongly negative association with a range of development indicators relative to their highest-quality GIS-based counterparts.


2005 ◽  
Vol 61 (2) ◽  
Author(s):  
J. M. Frantz

There is mounting evidence of the rising incidence and prevalence of non-communicable diseases in developing countries. Governments are facing serious challenges in health care due to the rising trends in non-communicable diseases as a result of demographic and epidemiological changes, as well as economic globalization. Cardiovascular disease, cancers, diabetes, respiratory disease, obesity andother non-communicable conditions now account for 59 percent of the 56.5 million global deaths annually, and almost half, or 46 percent, of the global burden of disease. It is estimated that by 2020, non-communicable diseases will account for 60% of the global burden of disease. The burden of non-communicable diseases in sub-Saharan Africa is already substantial, and patients with these conditions make significant demands on health resources. How do these changes affect physiotherapists? This paper aims to highlight the need for physiotherapists to shift their focus from curative to preventive care in order to face the challenge of non-communicable diseases.


2016 ◽  
Vol 15 (4) ◽  
pp. 406-418
Author(s):  
Edwina Kofi-Opata

Energy lies at the core of every human activity and can be described as having a pervasive influence on all aspects of development making it one of the most important resources that belies the development of any given country. Developing countries on the other hand are constantly faced with the daunting task of providing its industries and citizens with energy in its various forms. The resulting effect is limiting economic development and by extension limited social development. In meeting this need, the Ghanaian populace have and continue to rely on traditional biomass amid associated risks and health complications. This article analyzes the factors accounting for the heavy reliance on traditional biomass in Sub Saharan Africa (ssa) with particular reference to Ghana and to determine if these factors promote a spatial pattern formation in energy use.


2019 ◽  
Vol 7 (5) ◽  
pp. 133 ◽  
Author(s):  
Laura I. Levi ◽  
Marco Vignuzzi

Arthritogenic alphaviruses are responsible for a dengue-like syndrome associated with severe debilitating polyarthralgia that can persist for months or years and impact life quality. Chikungunya virus is the most well-known member of this family since it was responsible for two worldwide epidemics with millions of cases in the last 15 years. However, other arthritogenic alphaviruses that are as of yet restrained to specific territories are the cause of neglected tropical diseases: O’nyong’nyong virus in Sub-Saharan Africa, Mayaro virus in Latin America, and Ross River virus in Australia and the Pacific island countries and territories. This review evaluates their emerging potential in light of the current knowledge for each of them and in comparison to chikungunya virus.


Parasitology ◽  
2013 ◽  
Vol 140 (12) ◽  
pp. 1478-1491 ◽  
Author(s):  
SAM ALSFORD ◽  
JOHN M. KELLY ◽  
NICOLA BAKER ◽  
DAVID HORN

SUMMARYThe trypanosomes cause two neglected tropical diseases, Chagas disease in the Americas and African trypanosomiasis in sub-Saharan Africa. Over recent years a raft of molecular tools have been developed enabling the genetic dissection of many aspects of trypanosome biology, including the mechanisms underlying resistance to some of the current clinical and veterinary drugs. This has led to the identification and characterization of key resistance determinants, including transporters for the anti-Trypanosoma bruceidrugs, melarsoprol, pentamidine and eflornithine, and the activator of nifurtimox-benznidazole, the anti-Trypanosoma cruzidrugs. More recently, advances in sequencing technology, combined with the development of RNA interference libraries in the clinically relevant bloodstream form ofT. bruceihave led to an exponential increase in the number of proteins known to interact either directly or indirectly with the anti-trypanosomal drugs. In this review, we discuss these findings and the technological developments that are set to further revolutionise our understanding of drug-trypanosome interactions. The new knowledge gained should inform the development of novel interventions against the devastating diseases caused by these parasites.


2021 ◽  
Vol 15 (2) ◽  
pp. e0009131 ◽  
Author(s):  
Elizabeth A. Ochola ◽  
Diana M. S. Karanja ◽  
Susan J. Elliott

Neglected Tropical Diseases (NTDs) remain endemic to many regions of sub-Saharan Africa (SSA) left behind by socioeconomic progress. As such, these diseases are markers of extreme poverty and inequity that are propagated by the political, economic, social, and cultural systems that affect health and wellbeing. As countries embrace and work towards achieving the Sustainable Development Goals (SDGs), the needs of such vulnerable populations need to be addressed in local and global arenas. The research uses primary qualitative data collected from five NTD endemic counties of Kenya: interviews key informants (n = 21) involved in NTD implementation programs and focus groups (n = 5) of affected individuals. Informed by theories of political ecology of health, the research focuses on post-devolution Kenya and identifies the political, economic, social, and cultural factors that propagate NTDs and their effects on health and wellbeing. Our findings indicate that structural factors such as competing political interests, health worker strikes, inadequate budgetary allocations, economic opportunity, marginalization, illiteracy, entrenched cultural norms and practices, poor access to water, sanitation and housing, all serve to propagate NTD transmission and subsequently affect the health and wellbeing of populations. As such, we recommend that post-devolution Kenya ensures local political, economic and socio-cultural structures are equitable, sensitive and responsive to the needs of all people. We also propose poverty alleviation through capacity building and empowerment as a means of tackling NTDs for sustained economic opportunity and productivity at the local and national level.


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