scholarly journals Operative Risk Factors of Colon Resection in the Elderly

1980 ◽  
Vol 192 (6) ◽  
pp. 743-746 ◽  
Author(s):  
J. BARRY BOYD ◽  
BERT BRADFORD ◽  
ALVIN L. WATNE
Keyword(s):  
Risk Factors ◽  
The Elderly ◽  
Colon Resection ◽  
Operative Risk

scholarly journals A prospective cohort study of older colorectal cancer surgical patients: an association of post-operative clinical outcome with sarcopenia, frailty, and nutritional status [Protocol] (Preprint)

2019 ◽  
Author(s):  
Nia Humphry
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Nutritional Status ◽  
Significant Proportion ◽  
The Elderly ◽  
Operative Risk ◽  
Surgical Patients ◽  
Clinical Frailty Scale ◽  
Colorectal Cancer Surgery ◽  
Colorectal Cancer Resection

UNSTRUCTURED Older patients account for a significant proportion of patients undergoing colorectal cancer surgery, and are vulnerable to a number of pre-operative risk factors that are not often present in younger patients. Three pre-operative risk factors more prevalent in the elderly are frailty, sarcopenia, and malnutrition. Whilst each of these has been studied in isolation, there is little information on the interplay between them in older surgical patients. One particular area of increasing interest is the use of urine metabolomics for objective evaluation of dietary profiles and malnutrition. Herein we describe the design, cohort, and standard operating procedures of a planned prospective study of older surgical patients undergoing colorectal cancer resection across multiple institutions in the United Kingdom. These procedures include serial frailty evaluations (Clinical Frailty Scale and Groningen Frailty Indicator), functional assessments (with hand grip strength and 4-metre walk test), muscle mass evaluations using computerized tomography morphometric analysis and evaluation of nutritional status using analysis of urinary dietary biomarkers. As these are all areas of common derangement in the elderly surgical population, prospectively studying them in concert will allow for analysis of their interplay as well as the development of predictive models for those at risk for commonly tracked surgical complications and outcomes.

The operative risk factors of cholelithiasis in the elderly

Surgery Today ◽  
1992 ◽  
Vol 22 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Nagao Shinagawa ◽  
Keiji Mashita ◽  
Jiro Yura
Keyword(s):  
Risk Factors ◽  
The Elderly ◽  
Operative Risk

Laparoscopic cholecystectomy in the elderly: Analysis of pre-operative risk factors and postoperative complications

1995 ◽  
Vol 10 (5) ◽  
pp. 517-522 ◽  
Author(s):  
KENICHI IDO ◽  
TAKANORI SUZUKI ◽  
KEN KIMURA ◽  
YUSHI TANIGUCHI ◽  
CHIAKI KAWAMOTO ◽  
...  
Keyword(s):  
Risk Factors ◽  
Laparoscopic Cholecystectomy ◽  
Postoperative Complications ◽  
The Elderly ◽  
Operative Risk

788 Risk factors for rehospitalization in the elderly with chronic heart failure with preserved and impaired systolic function

2007 ◽  
Vol 6 (1) ◽  
pp. 180-180
Author(s):  
S BOZINOVIC ◽  
A GRDINIC ◽  
D STAMENKOVIC ◽  
M STOJADINOVIC ◽  
I MARKOVIC ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Chronic Heart Failure ◽  
Systolic Function ◽  
The Elderly

Differences in physical function and metabolic syndrome risk factors according to the level of physical activity in elderly Korean men: a pilot study

2020 ◽  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Metabolic Syndrome ◽  
Physical Function ◽  
Vigorous Physical Activity ◽  
Density Lipoprotein ◽  
The Elderly ◽  
Berg Balance Scale ◽  
Lower Percentage ◽  
Mineral Density

Background and objective: Managing the decrease in physical function in the elderly is a major task in aging societies globally. Here, we aimed to compare the physical function and metabolic syndrome (MetS) risk factors according to levels of physical activity (PA). Material and methods: We measured PA in 77 elderly Korean men (74.21 ± 6.26 years old) with an accelerometer and recorded body composition, physical function, and MetS-related risk factors. Participants were divided into three groups based on daily moderate-vigorous physical activity (MVPA): low (under 60 min), middle (60-120 min), and high (over 120 min). The groups were compared using a one-way analysis of variance and the Scheffe post hoc test. Odds ratios (OR) were calculated by logistic regression analysis. Results: Significant differences were found between the groups for sedentary behavior time (P < 0.001), light PA (P < 0.05), moderate PA (P < 0.001), vigorous PA (P < 0.05), and total energy expenditure (P < 0.001). The high PA group showed a significantly lower percentage of body fat and fat mass and higher muscle mass than did the low and middle PA groups (P < 0.05). The 6-min walk test was significantly better in the high PA group than in the low and middle PA groups (P < 0.05). Grip strength and the Berg balance scale were also significantly better in the high PA group (P < 0.05). Bone mineral density (BMD) and high-density lipoprotein cholesterol (HDL-C) were significantly higher in the high PA group than in the low PA group (P < 0.05). Systolic blood pressure (SBP) was significantly higher in the middle PA group than in the low PA group (P < 0.05). Participants with more than three MetS criteria showed an OR of 0.09 (95% confidence interval 0.01-0.82) in the high PA group as compared with the low PA group (P < 0.05). Conclusions: Moderate-vigorous physical activity of more than 120 min daily showed better physical function and lower OR of MetS than did lower MVPA levels in elderly Korean men.

Tissular Senescence and Modifications of Oral Ecosystem in the Elderly: Risk Factors for Mucosal Pathologies

2009 ◽  
Vol 2 (2) ◽  
pp. 109-120 ◽  
Author(s):  
Agnes Bodineau ◽  
Marysette Folliguet ◽  
Sylvie Seguier
Keyword(s):  
Risk Factors ◽  
The Elderly

scholarly journals Risk factors and mechanisms of stroke in young adults: The FUTURE study

2017 ◽  
Vol 38 (9) ◽  
pp. 1631-1641 ◽  
Author(s):  
Mayte E van Alebeek ◽  
Renate M Arntz ◽  
Merel S Ekker ◽  
Nathalie E Synhaeve ◽  
Noortje AMM Maaijwee ◽  
...  
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Future Study ◽  
The Elderly ◽  
Classification Systems ◽  
Unknown Etiology ◽  
Stroke Patients ◽  
Young Stroke ◽  
Starting Point ◽  
The Future

Incidence of ischemic stroke and transient ischemic attack in young adults is rising. However, etiology remains unknown in 30–40% of these patients when current classification systems designed for the elderly are used. Our aim was to identify risk factors according to a pediatric approach, which might lead to both better identification of risk factors and provide a stepping stone for the understanding of disease mechanism, particularly in patients currently classified as “unknown etiology”. Risk factors of 656 young stroke patients (aged 18–50) of the FUTURE study were categorized according to the “International Pediatric Stroke Study” (IPSS), with stratification on gender, age and stroke of “unknown etiology”. Categorization of risk factors into ≥1 IPSS category was possible in 94% of young stroke patients. Chronic systemic conditions were more present in patients aged <35 compared to patients ≥35 (32.6% vs. 15.6%, p < 0.05). Among 226 patients classified as “stroke of unknown etiology” using TOAST, we found risk factors in 199 patients (88%) with the IPSS approach. We identified multiple risk factors linked to other mechanisms of stroke in the young than in the elderly . This can be a valuable starting point to develop an etiologic classification system specifically designed for young stroke patients.

scholarly journals Neovascular Macular Degeneration: A Review of Etiology, Risk Factors, and Recent Advances in Research and Therapy

2021 ◽  
Vol 22 (3) ◽  
pp. 1170
Author(s):  
Arunbalaji Pugazhendhi ◽  
Margaret Hubbell ◽  
Pooja Jairam ◽  
Balamurali Ambati
Keyword(s):  
Risk Factors ◽  
Macular Degeneration ◽  
Kinase Inhibitors ◽  
Rho Kinase ◽  
The Elderly ◽  
Age Related Macular Degeneration ◽  
Gene Therapies ◽  
Rho Kinase Inhibitors ◽  
Age Related ◽  
Endothelial Growth Factor

Neovascular age-related macular degeneration (exudative or wet AMD) is a prevalent, progressive retinal degenerative macular disease that is characterized by neovascularization of the choroid, mainly affecting the elderly population causing gradual vision impairment. Risk factors such as age, race, genetics, iris color, smoking, drinking, BMI, and diet all play a part in nvAMD’s progression, with anti-vascular endothelial growth factor (anti-VEGF) therapy being the mainstay of treatment. Current therapeutic advancements slow the progression of the disease but do not cure or reverse its course. Newer therapies such as gene therapies, Rho-kinase inhibitors, and levodopa offer potential new targets for treatment.

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