Family History of Coronary Heart Disease, a Strong Risk Factor for Myocardial Infarction Interacting with Other Cardiovascular Risk Factors: Results from the Stockholm Heart Epidemiology Program (SHEEP)

Epidemiology ◽  
2001 ◽  
Vol 12 (2) ◽  
pp. 215-221 ◽  
Author(s):  
Karin Leander ◽  
Johan Hallqvist ◽  
Christina Reuterwall ◽  
Anders Ahlbom ◽  
and Ulf de Faire
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Heart Disease ◽  
Risk Factor ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Family History ◽  
Cardiovascular Risk Factors ◽  
Strong Risk Factor ◽  
History Of

The correlation of apolipoprotein B, apolipoprotein B/apolipoprotein A-I ratio and lipoprotein(a) with myocardial infarction

Open Medicine ◽  
2008 ◽  
Vol 3 (4) ◽  
pp. 422-429
Author(s):  
Lucia Agoston-Coldea ◽  
Teodora Mocan ◽  
Marc Gatfossé ◽  
Dan Dumitrascu
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Total Cholesterol ◽  
Cardiovascular Risk Factors ◽  
Apolipoprotein B ◽  
Hdl Cholesterol ◽  
Lipoprotein A

AbstractRecent evidence shows that apolipoprotein (apo) B, apoB/apoA-I ratio and lipoprotein(a) are better indicators of coronary risk than the conventional lipid profile. The aim of this study was to evaluate the correlation of apoA-I and B, and lipoprotein(a) with myocardial infarction (MI). We performed a cross-sectional study including 208 patients (100 men and 108 women), with and without previous MI evaluated by coronary angiography. The severity of coronary heart disease was scored on the basis of the number and extent of lesions in the coronary arteries. Lipid levels were measured by the enzymatic method and apolipoprotein levels were measured by the immunoturbidimetric method. The MI group had higher plasmatic levels of lipoprotein(a) (0.37±0.28 vs. 0.29±0.23 g/L, p<0.05), apoB (1.13±0.40 vs. 0.84±0.28 g/L, p<0.05) and of the apoB/apoA-I ratio (0.77±0.37 vs. 0.68±0.20, p<0.05) compared to controls. The area under the receiver operating characteristic (ROC) curves (AUC) suggested a good reliability in the diagnose of coronary heart disease for the apoB/apoA-I ratio (0.756, p<0.05), apoB (0.664, p<0.05), lipoprotein(a) (0.652, p<0.05) and total cholesterol/HDL-cholesterol (0.688, p<0.05). Multivariate analysis performed with adjustments for cardiovascular risk factors, showed that the levels of lipoprotein(a), apoB and apoB/apoA-I ratio are significant independent cardiovascular risk factors. Our results indicate that there is an important relationship among high plasma apoB concentration, lipoprotein(a) concentration, the apoB/apoA-I ratio, and MI. We showed that the apoB/apoA-I ratio has a stronger correlation with MI than the total cholesterol/HDL cholesterol ratio. We therefore suggest using apoB/apoA-I ratio and lipoprotein(a) in clinical practice as a markers of MI risk.

scholarly journals Cardiovascular risk factors in workers at Health Centre in Beocin

2008 ◽  
Vol 61 (5-6) ◽  
pp. 257-262 ◽  
Author(s):  
Biljana Petrovic ◽  
Zlata Jasarevic-Komljenovic ◽  
Biljana Srdic ◽  
Edita Stokic
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Family History ◽  
Cardiovascular Diseases ◽  
Cardiovascular Risk Factors ◽  
Health Workers ◽  
Health Centre

Most cardiovascular diseases are caused by atherosclerosis, which is a result of interactions between risk factors such as gender, age, blood lipid concentrations, blood pressure, glucose tolerance, adiposity, physical activity and cigarette smoking. Identification of risk factors is the first step in cardiovascular disease prevention. As health workers contribute significantly to cardiovascular morbidity, the aim of our study was to analyze prevalence of cardiovascular risk factors and to assess the level of mentioned risk in health workers employed in Health Centre Beocin. The study group consisted of 50 health workers. Obesity was evaluated according to BMI and body fat (BF%) values, while central obesity was defined using waist circumference. Serum lipid concentrations and glycaemia were used in metabolic profile definition. The level of physical activity was assessed using IPAQ, and information about smoking status and family history of cardiovascular diseases was obtained from self-report. Framingham point-scoring system was used to predict the risk for development of coronary heart disease in the 10-year period. Overweight was found in 36%, and obesity in 18% subjects. 42% of examined subjects had higher fat mass, while 24% of them had obesity. Central fat accumulation was observed in 50% subjects. We registered 56% smokers, 70% subjects with positive family history, 28% subjects with hypertension, and 56% subjects with dyslipidemia. According to IPAQ results 20% of exanimate subjects were minimally active and 70% were insufficiently active. Estimated risk of coronary heart disease was 7.38%, and 10% subjects had risk over 20%. In spite of lower cardiovascular risk level, our results showed high prevalence of overweight, smoking and physical inactivity in health workers, which suggests the importance of their own lifestyle modification. It should be the first step in increasing motivation of their patients.

Sex disparities in the management of coronary heart disease in general practices in Australia

Heart ◽  
2019 ◽  
Vol 105 (24) ◽  
pp. 1898-1904 ◽  
Author(s):  
Crystal Man Ying Lee ◽  
George Mnatzaganian ◽  
Mark Woodward ◽  
Clara K Chow ◽  
Freddy Sitas ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
General Practice ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Large Scale ◽  
Management Plan ◽  
History Of ◽  
Sex Disparities

ObjectivesTo determine whether sex differences exist in the management of patients with a history of coronary heart disease (CHD) in primary care.MethodsGeneral practice records of patients aged ≥18 years with a history of CHD in a large general practice dataset in Australia, MedicineInsight, were analysed. Sex-specific, age-standardised proportions of patients prescribed with recommended medications; assessed for cardiovascular risk factors; and achieved treatment targets according to the General Practice Management Plan were reported.ResultsRecords of 130 926 patients (47% women) from 438 sites were available from 2014 to 2018. Women were less likely to be prescribed with recommended medications (prescribed ≥3 medications: women 44%, men 61%; p<0.001). Younger patients, especially women aged <45 years, were substantially underprescribed (aged <45 years prescribed ≥3 medications: women 2%, men 8%; p<0.001). Lower proportions of women were assessed for cardiovascular risk factors (blood test for lipids: women 70%–76%, men 77%–81%; p<0.001). Body size was not commonly assessed (body mass index: women 59%, men 62%; p<0.001; waist: women 23%, men 25%; p<0.001). Higher proportions of women than men achieved targets for most risk factors (achieved ≥4 targets in patients assessed for all risk factors: women 82%, men 76%).ConclusionGaps in preventative management including prescription of indicated medications and risk factor monitoring have been reported from the late 1990s and this large-scale general practice data analysis indicate they still persist. Moreover, the gap is larger in women compared to men. We need new ways to address these gaps and the sex inequity.

The Joint Impact of Family History of Myocardial Infarction and Other Risk Factors on 12-year Coronary Heart Disease Mortality

Epidemiology ◽  
1999 ◽  
Vol 10 (6) ◽  
pp. 767-770 ◽  
Author(s):  
Jolanda M. A. Boer ◽  
Edith J. M. Feskens ◽  
W. M. Monique Verschuren ◽  
Jacob C. Seidell ◽  
Daan Kromhout
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Family History ◽  
Coronary Heart Disease Mortality ◽  
Disease Mortality ◽  
History Of

CARDIOVASCULAR RISK FACTORS PECULIARITIES IN MEN UNDER 60 YEARS OLD WITH MYOCARDIAL INFARCTION AND CHRONIC INFLAMMATORY LUNG DISEASES

2020 ◽  
pp. 21-25
Author(s):  
Tupitsyn V.V. ◽  
Bataev Kh.M. ◽  
Men’shikova A.N. ◽  
Godina Z.N.
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Digestive System ◽  
Control Group ◽  
Study Group ◽  
Type I ◽  
Internal Organs ◽  
History Of

Relevance. Information about the cardiovascular diseases risk factors (CVD RF) for in men with chronic lung inflam-matory pathology (CLID) is contradictory and requires clarification. Aim. To evaluate the peculiarities of CVD RF in men under 60 years of age with CLID in myocardial infarction (MI) to improve prevention. Material and methods. The study included men aged 19-60 years old with type I myocardial infarction. Patients are divided into two age-comparable groups: I - the study group, with CLID - 142 patients; II - control, without it - 424 patients. A comparative analysis of the frequency of observation of the main and additional cardiovascular risk fac-tors in groups was performed. Results. In patients of the study group, more often than in the control group we observed: hereditary burden of is-chemic heart disease (40.8 and 31.6%, respectively; p = 0.0461) and arterial hypertension (54.2 and 44.6%; p = 0.0461), frequent colds (24.6 and 12.0%; p = 0.0003), a history of extrasystoles (19.7 and 12.7%; p = 0.04); chronic foci of infections of internal organs (75.4 and 29.5%; p˂0.0001), non-ulcer lesions of the digestive system (26.1 and 14.6%; p = 0.007), smoking (95.1 and 66.3%; p˂0.0001), MI in winter (40.8 and 25.9%; p = 0.006). Less commonly were observed: oral cavity infections (9.2 and 23.6%; p˂0.0001); hypodynamia (74.5 and 82.5%; p = 0.0358), over-weight (44.4 and 55.2%; p = 0.0136), a subjective relationship between the worsening of the course of coronary heart disease and the season of the year (43.7 and 55.2%; p = 0.0173) and MI - in the autumn (14.1 and 21.9%; p = 0.006) period. Conclusions. The structure of CVD RF in men under 60 years of age with CLID with MI is characterized by the pre-dominance of smoking, non-ulcer pathology of the digestive system, frequent pro-student diseases, meteorological dependence, a history of cardiac arrhythmias and foci of internal organ infections. It is advisable to use the listed factors when planning preventive measures in such patients.

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