scholarly journals Time series proteome profile analysis reveals a protective role of citrate synthase in angiotensin II-induced atrial fibrillation

2022 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Fei Teng ◽  
Xiao Han ◽  
Peng Yu ◽  
Pang-Bo Li ◽  
Hui-Hua Li ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Time Series ◽  
Angiotensin Ii ◽  
Citrate Synthase ◽  
Profile Analysis ◽  
Protective Role ◽  
Proteome Profile

Losartan Increases No Production from the Bovine Aortic Wall That is Stimulated by Angiotensin II

2003 ◽  
Vol 1 (3) ◽  
pp. 113-117 ◽  
Author(s):  
M. Myronidou ◽  
B. Kokkas ◽  
A. Kouyoumtzis ◽  
N. Gregoriadis ◽  
A. Lourbopoulos ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Angiotensin Ii ◽  
Aortic Wall ◽  
Vascular Wall ◽  
Protective Role ◽  
Normal Function ◽  
No Production ◽  
Chemical Inactivation

In these studies we investigated if losartan, an AT1- receptor blocker has any beneficial effect on NO production from the bovine aortic preparations in vitro while under stimulation from angiotensin II. Experiments were performed on intact specimens of bovine thoracic aorta, incubated in Dulbeco's MOD medium in a metabolic shaker for 24 hours under 95 % O2 and 5 % CO2 at a temperature of 37°C. We found that angiotensin II 1nM−10 μM does not exert any statistically significant action on NO production. On the contrary, angiotensin II 10nM increases the production of NO by 58.14 % (from 12.16 + 2.9 μm/l to 19.23 + 4.2 μm/l in the presence of losartan 1nM (P<0.05). Nitric oxide levels depend on both rate production and rate catabolism or chemical inactivation. Such an equilibrium is vital for the normal function of many systems including the cardiovascular one. The above results demonstrate that the blockade of AT1-receptors favors the biosynthesis of NO and indicate the protective role of losartan on the vascular wall.

Protective Role of Medications on Atrial Fibrillation and Heart Failure with Preserved Ejection Fraction

2014 ◽  
Vol 20 (8) ◽  
pp. S121
Author(s):  
Arnav Kumar ◽  
Amarpreet K. Saluja ◽  
Adnan Khan ◽  
Mohammad Morsy ◽  
Wissam I. Khalife
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Ejection Fraction ◽  
Protective Role ◽  
Preserved Ejection Fraction

scholarly journals Protective role of vascular smooth muscle cell PPARγ in angiotensin II-induced vascular disease

2012 ◽  
Vol 97 (3) ◽  
pp. 562-570 ◽  
Author(s):  
Chiara Marchesi ◽  
Asia Rehman ◽  
Yohann Rautureau ◽  
Daniel A. Kasal ◽  
Marie Briet ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Angiotensin Ii ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Vascular Disease ◽  
Muscle Cell ◽  
Vascular Smooth Muscle Cell ◽  
Protective Role

scholarly journals Protective Role of Angiotensin II Type 1 Receptor Blocker on Short Time Effect of Oleic Acid Induced Lung and Kidney Injury

2021 ◽  
Vol 12 (1) ◽  
pp. 4
Author(s):  
Mehdi Nematbakhsh ◽  
Ardeshir Talebi ◽  
Fatemeh Emami ◽  
Reza Biranvand ◽  
Zahra Moosavi ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Angiotensin Ii ◽  
Kidney Injury ◽  
Protective Role ◽  
Time Effect ◽  
Receptor Blocker ◽  
Short Time ◽  
Lung And Kidney
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