scholarly journals The fixation probability of beneficial mutations

2008 ◽  
Vol 5 (28) ◽  
pp. 1279-1289 ◽  
Author(s):  
Z Patwa ◽  
L.M Wahl

The fixation probability, the probability that the frequency of a particular allele in a population will ultimately reach unity, is one of the cornerstones of population genetics. In this review, we give a brief historical overview of mathematical approaches used to estimate the fixation probability of beneficial alleles. We then focus on more recent work that has relaxed some of the key assumptions in these early papers, providing estimates that have wider applicability to both natural and laboratory settings. In the final section, we address the possibility of future work that might bridge the gap between theoretical results to date and results that might realistically be applied to the experimental evolution of microbial populations. Our aim is to highlight the concrete, testable predictions that have arisen from the theoretical literature, with the intention of further motivating the invaluable interplay between theory and experiment.

Author(s):  
Anthony Kwame Harrison

This chapter introduces ethnography as a distinct research and writing tradition. It opens with a discussion of ethnography’s current fashionability within transdisciplinary academic spaces and some of the associated challenges. The next section provides a historical overview of ethnography’s emergence as a professionalized research practice within the fields of anthropology and sociology. Focusing on ethnography as a research methodology, the chapter outlines several key attributes that distinguish it from other forms of participant observation–oriented research; provides a general overview of the central paradigms that ethnographers claim and/or move between; and spotlights three principal research methods that most ethnographers utilize—namely, participant observation, field-note writing, and ethnographic interviewing. The final section of the chapter introduces a research disposition called ethnographic comportment, defined as a politics of positionality that reflects both ethnographers’ awarenesses of and their accountabilities to the research tradition they participate in.


2021 ◽  
pp. 103530462110147
Author(s):  
Mark Dean ◽  
Al Rainnie ◽  
Jim Stanford ◽  
Dan Nahum

This article critically analyses the opportunities for Australia to revitalise its strategically important manufacturing sector in the wake of the COVID-19 pandemic. It considers Australia’s industry policy options on the basis of both advances in the theory of industrial policy and recent policy proposals in the Australian context. It draws on recent work from The Australia Institute’s Centre for Future Work examining the prospects for Australian manufacturing renewal in a post-COVID-19 economy, together with other recent work in political economy, economic geography and labour process theory critically evaluating the Fourth Industrial Revolution (i4.0) and its implications for the Australian economy. The aim of the article is to contribute to and further develop the debate about the future of government intervention in manufacturing and industry policy in Australia. Crucially, the argument links the future development of Australian manufacturing with a focus on renewable energy. JEL Codes: L50; L52; L78; O10; O13: O25; O44; P18; Q42


2020 ◽  
Vol 23 (3) ◽  
pp. 873-894
Author(s):  
Markus Kinateder ◽  
Hubert János Kiss ◽  
Ágnes Pintér

Abstract In a Diamond–Dybvig type model of financial intermediation, we allow depositors to announce at a positive cost to subsequent depositors that they keep their funds deposited in the bank. Theoretically, the mere availability of public announcements (and not its use) ensures that no bank run is the unique equilibrium outcome. Multiple equilibria—including bank run—exist without such public announcements. We test the theoretical results in the lab and find a widespread use of announcements, which we interpret as an attempt to coordinate on the no bank run outcome. Withdrawal rates in general are lower in information sets that contain announcements.


1993 ◽  
Vol 115 (4) ◽  
pp. 427-435 ◽  
Author(s):  
K. Gupta ◽  
K. D. Gupta ◽  
K. Athre

A dual rotor rig is developed and is briefly discussed. The rig is capable of simulating dynamically the two spool aeroengine, though it does not physically resemble the actual aeroengine configuration. Critical speeds, mode shape, and unbalance response are determined experimentally. An extended transfer matrix procedure in complex variables is developed for obtaining unbalance response of dual rotor system. Experimental results obtained are compared with theoretical results and are found to be in reasonable agreement.


Author(s):  
Ken Brown ◽  
Angela Ankomaah Tabiri

AbstractLet $\mathcal {C}$ C be a decomposable plane curve over an algebraically closed field k of characteristic 0. That is, $\mathcal {C}$ C is defined in k2 by an equation of the form g(x) = f(y), where g and f are polynomials of degree at least two. We use this data to construct three affine pointed Hopf algebras, A(x, a, g), A(y, b, f) and A(g, f), in the first two of which g [resp. f ] are skew primitive central elements, with the third being a factor of the tensor product of the first two. We conjecture that A(g, f) contains the coordinate ring $\mathcal {O}(\mathcal {C})$ O ( C ) of $\mathcal {C}$ C as a quantum homogeneous space, and prove this when each of g and f has degree at most five or is a power of the variable. We obtain many properties of these Hopf algebras, and show that, for small degrees, they are related to previously known algebras. For example, when g has degree three A(x, a, g) is a PBW deformation of the localisation at powers of a generator of the downup algebra A(− 1,− 1,0). The final section of the paper lists some questions for future work.


2018 ◽  
Author(s):  
Gabriela K. Fragiadakis ◽  
Samuel A. Smits ◽  
Erica D. Sonnenburg ◽  
William Van Treuren ◽  
Gregor Reid ◽  
...  

AbstractThe study of traditional populations provides a view of human-associated microbes unperturbed by industrialization, as well as a window into the microbiota that co-evolved with humans. Here we discuss our recent work characterizing the microbiota from the Hadza hunter-gatherers of Tanzania. We found seasonal shifts in bacterial taxa, diversity, and carbohydrate utilization by the microbiota. When compared to the microbiota composition from other populations around the world, the Hadza microbiota shares bacterial families with other traditional societies that are rare or absent from microbiotas of industrialized nations. We present additional observations from the Hadza microbiota and their lifestyle and environment, including microbes detected on hands, water, and animal sources, how the microbiota varies with sex and age, and the shortterm effects of introducing agricultural products into the diet. In the context of our previously published findings and of these additional observations, we discuss a path forward for future work.


1976 ◽  
Vol 73 ◽  
pp. 173-192
Author(s):  
G. T. Bath

Recent work on the physical processes resulting from mass transfer between the red and blue components of dwarf nova binaries is reviewed. The optical behaviour of the blue component's accretion disc suggests that it may be the infall, accretion energy which is being liberated during outbursts. Theoretical results which suggest that the red component may suffer quasi-periodic mass transfer instabilities are discussed. The resulting accretion disc properties are considered and compared with the observed optical outburst behaviour for the simplest steady state disc models. The complexity of the interaction between the two stellar components in these systems is emphasized.


This collection provides a guide to the mystical element of Christianity as a theological phenomenon. It differs not only from psychological and anthropological studies of mysticism, but from other theological studies, such as more practical or pastorally oriented works that examine the patterns of spiritual progress and offer counsel for deeper understanding and spiritual development. It also differs from more explicitly historical studies tracing the theological and philosophical contexts and ideas of various key figures and schools, as well as from literary studies of the linguistic tropes and expressive forms in mystical texts. None of these perspectives is absent, but the method here is more deliberately theological, working from within the fundamental interests of Christian mystical writers to the articulation of those interests in distinctively theological forms, in order, finally, to permit a critical theological engagement with them for today. Divided into four parts, the first section introduces the approach to mystical theology and offers a historical overview. Part II attends to the concrete context of sources and practices of mystical theology. Part III moves to the fundamental conceptualities of mystical thought. The final section presents the central contributions of mystical teaching to theology and metaphysics. Students and scholars with a variety of interests will find different pathways through the Handbook.


1990 ◽  
Vol 16 (2) ◽  
pp. 399-432 ◽  
Author(s):  
Jerald Greenberg

The present article chronicles the history of the field of organizational justice, identifies current themes, and recommends new directions for the future. A historical overview of the field focuses on research and theory in the distributive justice tradition (e.g., equity theory) as well as the burgeoning topic of procedural justice. This forms the foundation for the discussion offive popular themes in contemporary organizational justice research: (a) attempts to distinguish procedural justice and distributive justice empirically, (b) the development of new conceptual advances, (c) consideration of the interpersonal determinants of procedural justice judgments, (d) new directions in tests of equity theory, and (e) applications of justice-based explanations to many different organizational phenomena. In closing, a plea is made for future work that improves procedural justice research methodologically (with respect to scope, setting, and scaling), and that attempts to integrate and unify disparate concepts in the distributive and procedural justice traditions.


1993 ◽  
Vol 07 (01n03) ◽  
pp. 203-206 ◽  
Author(s):  
PER SÖDERLIND ◽  
JOHN WILLS ◽  
OLLE ERIKSSON

The shear elastic constant, C′, is calculated from first principles for the cubic 4d and 5d transition elements. This study also includes calculations for selected alloys using the virtual crystal approximation. The tetragonal shear constant for these elements and alloys is found to follow a trend which can be related to the calculated crystal structure stabilities. In fact, the trend of C′ behaves roughly as the the trend displayed by the energy difference between the fcc and bcc crystal structures. The theoretical results are generally in ~90% agreement with experiment for the tetragonal shear constant and this implies indirectly that the discrepancy between theory and experiment found for the crystal energies do not lie in the theoretical data.


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