scholarly journals Simulated shift work in rats perturbs multiscale regulation of locomotor activity

2014 ◽  
Vol 11 (96) ◽  
pp. 20140318 ◽  
Author(s):  
Wan-Hsin Hsieh ◽  
Carolina Escobar ◽  
Tatiana Yugay ◽  
Men-Tzung Lo ◽  
Benjamin Pittman-Polletta ◽  
...  
Keyword(s):  
Shift Work ◽  
Activity Rhythm ◽  
Activity Patterns ◽  
Activity Level ◽  
Activity Regulation ◽  
Wide Range ◽  
Fractal Patterns ◽  
Shift Work Schedule ◽  
Detrimental Impact

Motor activity possesses a multiscale regulation that is characterized by fractal activity fluctuations with similar structure across a wide range of timescales spanning minutes to hours. Fractal activity patterns are disturbed in animals after ablating the master circadian pacemaker (suprachiasmatic nucleus, SCN) and in humans with SCN dysfunction as occurs with aging and in dementia, suggesting the crucial role of the circadian system in the multiscale activity regulation. We hypothesized that the normal synchronization between behavioural cycles and the SCN-generated circadian rhythms is required for multiscale activity regulation. To test the hypothesis, we studied activity fluctuations of rats in a simulated shift work protocol that was designed to force animals to be active during the habitual resting phase of the circadian/daily cycle. We found that these animals had gradually decreased mean activity level and reduced 24-h activity rhythm amplitude, indicating disturbed circadian and behavioural cycles. Moreover, these animals had disrupted fractal activity patterns as characterized by more random activity fluctuations at multiple timescales from 4 to 12 h. Intriguingly, these activity disturbances exacerbated when the shift work schedule lasted longer and persisted even in the normal days (without forced activity) following the shift work. The disrupted circadian and fractal patterns resemble those of SCN-lesioned animals and of human patients with dementia, suggesting a detrimental impact of shift work on multiscale activity regulation.

scholarly journals Preprint of "Income Inequality Reduces Civic Honesty"

2020 ◽  
Author(s):  
Hongfei Du ◽  
Anli Chen ◽  
Peilian Chi ◽  
Ronnel B. King
Keyword(s):  
Experimental Design ◽  
Income Inequality ◽  
Crucial Role ◽  
Social Outcomes ◽  
Causal Effects ◽  
Wide Range ◽  
Multi Level ◽  
Detrimental Impact

Income inequality has been shown to have a detrimental impact on a wide range of psychological, economic, and social outcomes. In this study, we focus on the role of income inequality in reducing civic honesty. Study 1 reanalyzed data of a “lost wallet” experiment conducted by Cohn, Maréchal, Tannenbaum, and Zünd (2019) in 355 cities spread across 40 countries. Multi-level analyses indicated that citizens in countries with higher income inequality were less likely to return a lost wallet. Study 2 examined the causal effects of income inequality by utilizing an experimental design. We found that income inequality reduced one’s personal desire to return a lost wallet. Convergent findings from two studies indicate the crucial role played by income inequality in reducing civic honesty.

scholarly journals Better Park Design Contributes to Physical Activity Improvement

2020 ◽  
Vol 8 (4) ◽  
pp. 260-266
Author(s):  
Sigit Arifwidodo ◽  
Orana Chandrasiri
Keyword(s):  
Physical Activity ◽  
Vigorous Physical Activity ◽  
Activity Patterns ◽  
Activity Level ◽  
Least Square ◽  
Survey Questionnaire ◽  
Public Park ◽  
Wide Range ◽  
Park Design ◽  
Design Intervention

Objective - Empirical evidence has identified that parks hold an essential role in promoting physical activity. Parks facilitate opportunities to be physically active for a wide range of users. The paper explores the effects of design intervention of Benjakitti Park, a public park in Bangkok, Thailand. Methodology/Technique – The system for Observing Play and Recreation in Communities (SOPARC) method was utilized before and after design intervention to understand whether the design intervention improved the park users' physical activity level. A survey questionnaire of park visitors was used to understand whether they had become more active during a park visit. Finding –It was found that the design intervention changed the characteristics of park users and their activity patterns. More children and older adults' visitors were observed in the post-design intervention. An ordinary least square model of the survey questionnaire result showed that one-time park visitation was associated with an increase of five minutes of moderate and vigorous physical activity per week. The study showed that even a small design intervention could change people's behavior towards a healthier and more active lifestyle. Type of Paper: Empirical JEL Classification: C99, R19 Keywords: Public Park; Physical Activity; Landscape Design; Public Health; SOPARC. Reference to this paper should be made as follows: Arifwidodo, S; Chandrasiri, O. (2020). Better Park Design Contributes to Physical Activity Improvement, GATR Global J. Bus. Soc. Sci. Review, 8(4): 260 – 266. https://doi.org/10.35609/gjbssr.2020.8.4(7)

Potential role of melatonin in prevention and treatment of leukaemia

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Ming Guan Ng ◽  
Khuen Yen Ng ◽  
Rhun Yian Koh ◽  
Soi Moi Chye
Keyword(s):  
Shift Work ◽  
Potential Role ◽  
Synergistic Effects ◽  
Melatonin Receptors ◽  
Anticancer Compounds ◽  
Future Studies ◽  
Wide Range ◽  
Incidence Risk ◽  
The Relationship

Abstract Leukaemia is a haematological malignancy originated from the bone marrow. Studies have shown that shift work could disrupt the melatonin secretion and eventually increase leukaemia incidence risk. Melatonin, a pineal hormone, has shown promising oncostatic properties on a wide range of cancers, including leukaemia. We first reviewed the relationship between shift work and the incidence rate of leukaemia and then discussed the role of melatonin receptors (MT1 and MT2) and their functions in leukaemia. Moreover, the connection between inflammation and leukaemia, and melatonin-induced anti-leukaemia mechanisms including anti-proliferation, apoptosis induction and immunomodulation are comprehensively discussed. Apart from that, the synergistic effects of melatonin with other anticancer compounds are also included. In short, this review article has compiled the evidence of anti-leukaemia properties displayed by melatonin and discuss its potential to act as adjunct for anti-leukaemia treatment. This review may serve as a reference for future studies or experimental research to explore the possibility of melatonin serving as a novel therapeutic agent for leukaemia.

scholarly journals Income Inequality Reduces Civic Honesty

2020 ◽  
pp. 194855062092949 ◽  
Author(s):  
Hongfei Du ◽  
Anli Chen ◽  
Peilian Chi ◽  
Ronnel B. King
Keyword(s):  
Experimental Design ◽  
Income Inequality ◽  
Crucial Role ◽  
Social Outcomes ◽  
Causal Effects ◽  
Multilevel Analyses ◽  
Wide Range ◽  
Detrimental Impact

Income inequality has been shown to have a detrimental impact on a wide range of psychological, economic, and social outcomes. In this study, we focus on the role of income inequality in reducing civic honesty. Study 1 reanalyzed data of a “lost wallet” experiment conducted by Cohn, Maréchal, Tannenbaum, and Zuünd (2019) in 355 cities spread across 40 countries. Multilevel analyses indicated that citizens in countries with higher income inequality were less likely to return a lost wallet. Study 2 examined the causal effects of income inequality by utilizing an experimental design. We found that income inequality reduced one’s personal desire to return a lost wallet. Convergent findings from two studies indicate the crucial role played by income inequality in reducing civic honesty.

The Problem of Identifying and Modeling the Relationship between Monetary Factor and Inflation in the Russian Economy

2008 ◽  
pp. 61-76
Author(s):  
A. Porshakov ◽  
A. Ponomarenko
Keyword(s):  
Money Supply ◽  
Money Demand ◽  
Russian Economy ◽  
Long Run ◽  
Complex Approach ◽  
Wide Range ◽  
Long Time ◽  
The Relationship ◽  
Supply Side Factors

The role of monetary factor in generating inflationary processes in Russia has stimulated various debates in social and scientific circles for a relatively long time. The authors show that identification of the specificity of relationship between money and inflation requires a complex approach based on statistical modeling and involving a wide range of indicators relevant for the price changes in the economy. As a result a model of inflation for Russia implying the decomposition of inflation dynamics into demand-side and supply-side factors is suggested. The main conclusion drawn is that during the recent years the volume of inflationary pressures in the Russian economy has been determined by the deviation of money supply from money demand, rather than by money supply alone. At the same time, monetary factor has a long-run spread over time impact on inflation.

Introduction: Emotion, History and the Arts

2018 ◽  
Vol 7 (2) ◽  
pp. 117-128 ◽  
Author(s):  
Erin Sullivan ◽  
Marie Louise Herzfeld-Schild
Keyword(s):  
Historical Change ◽  
Carson Mccullers ◽  
Emotional Life ◽  
Review Section ◽  
The Arts ◽  
Wide Range ◽  
War Correspondents ◽  
History Of ◽  
Johan Huizinga

This introduction surveys the rise of the history of emotions as a field and the role of the arts in such developments. Reflecting on the foundational role of the arts in the early emotion-oriented histories of Johan Huizinga and Jacob Burkhardt, as well as the concerns about methodological impressionism that have sometimes arisen in response to such studies, the introduction considers how intensive engagements with the arts can open up new insights into past emotions while still being historically and theoretically rigorous. Drawing on a wide range of emotionally charged art works from different times and places—including the novels of Carson McCullers and Harriet Beecher-Stowe, the private poetry of neo-Confucian Chinese civil servants, the photojournalism of twentieth-century war correspondents, and music from Igor Stravinsky to the Beatles—the introduction proposes five ways in which art in all its forms contributes to emotional life and consequently to emotional histories: first, by incubating deep emotional experiences that contribute to formations of identity; second, by acting as a place for the expression of private or deviant emotions; third, by functioning as a barometer of wider cultural and attitudinal change; fourth, by serving as an engine of momentous historical change; and fifth, by working as a tool for emotional connection across communities, both within specific time periods but also across them. The introduction finishes by outlining how the special issue's five articles and review section address each of these categories, while also illustrating new methodological possibilities for the field.

Short Films from a Small Nation

2018 ◽  
Author(s):  
C. Claire Thomson
Keyword(s):  
Public Information ◽  
Industrial Process ◽  
Actor Network Theory ◽  
Documentary Films ◽  
Wide Range ◽  
Short Films ◽  
Post War ◽  
The 1960S ◽  
Art And Architecture

The first book-length study in English of a national corpus of state-sponsored informational film, this book traces how Danish shorts on topics including social welfare, industry, art and architecture were commissioned, funded, produced and reviewed from the inter-war period to the 1960s. For three decades, state-sponsored short filmmaking educated Danish citizens, promoted Denmark to the world, and shaped the careers of renowned directors like Carl Th. Dreyer. Examining the life cycle of a representative selection of films, and discussing their preservation and mediation in the digital age, this book presents a detailed case study of how informational cinema is shaped by, and indeed shapes, its cultural, political and technological contexts.The book combines close textual analysis of a broad range of films with detailed accounts of their commissioning, production, distribution and reception in Denmark and abroad, drawing on Actor-Network Theory to emphasise the role of a wide range of entities in these processes. It considers a broad range of genres and sub-genres, including industrial process films, public information films, art films, the city symphony, the essay film, and many more. It also maps international networks of informational and documentary films in the post-war period, and explores the role of informational film in Danish cultural and political history.

Quantitative and Qualitative Methods of Studying the Processes of Socialization of a Modern Teenager

2020 ◽  
pp. 102-109
Author(s):  
Svetlana Alekseevna Raschetina ◽  
Keyword(s):  
Research Methods ◽  
Interpersonal Relations ◽  
Internet Communication ◽  
Socialization Process ◽  
Wide Range ◽  
The Family ◽  
Modern Family ◽  
Making Friends ◽  
Main Support

Relevance and problem statement. Modern unstable society is characterized by narrowing the boundaries of controlled socialization and expanding the boundaries of spontaneous socialization of a teenager based on his immersion in the question arises about the importance of the family in the process of socialization of a teenager in the conditions of expanding the space of socialization. There is a need to study the role of the family in this process, to search, develop and test research methods that allow us to reveal the phenomenon of socialization from the side of its value characteristics. The purpose and methodology of the study: to identify the possibilities of a systematic and anthropological methodology for studying the role of the family in the process of socialization of adolescents in modern conditions, testing research methods: photo research on the topic “Ego – I” (author of the German sociologist H. Abels), profile update reflexive processes (by S. A. Raschetina). Materials and results of the study. The study showed that for all the problems that exist in the family of the perestroika era and in the modern family, it acts for a teenager as a value and the first (main) support in the processes of socialization. The positions well known in psychology about the importance of interpersonal relations in adolescence for the formation of attitudes towards oneself as the basis of socialization are confirmed. Today, the frontiers of making friends have expanded enormously on the basis of Internet communication. The types of activities of interest to a teenager (traditional and new ones related to digitalization) are the third pillar of socialization. Conclusion. The “Ego – I” method of photo research has a wide range of possibilities for quantitative and qualitative analysis of the socialization process to identify the value Pillars of this process.

Victorian Culture and Classical Antiquity

2011 ◽  
Author(s):  
Simon Goldhill
Keyword(s):  
Nineteenth Century ◽  
Roman Empire ◽  
Classical Antiquity ◽  
Victorian Culture ◽  
Wide Range ◽  
Victorian Art ◽  
Victorian Science ◽  
Role Of Religion ◽  
Nineteenth Century Novels

How did the Victorians engage with the ancient world? This book is an exploration of how ancient Greece and Rome influenced Victorian culture. Through Victorian art, opera, and novels, the book examines how sexuality and desire, the politics of culture, and the role of religion in society were considered and debated through the Victorian obsession with antiquity. Looking at Victorian art, it demonstrates how desire and sexuality, particularly anxieties about male desire, were represented and communicated through classical imagery. Probing into operas of the period, the book addresses ideas of citizenship, nationalism, and cultural politics. And through fiction—specifically nineteenth-century novels about the Roman Empire—it discusses religion and the fierce battles over the church as Christianity began to lose dominance over the progressive stance of Victorian science and investigation. Rediscovering some great forgotten works and reframing some more familiar ones, the book offers extraordinary insights into how the Victorian sense of antiquity and our sense of the Victorians came into being. With a wide range of examples and stories, it demonstrates how interest in the classical past shaped nineteenth-century self-expression, giving antiquity a unique place in Victorian culture.

Role of Cardiac MRI in Detecting Familial Hypertrophic Cardiomyopathy: Review

2016 ◽  
Vol 1 (1) ◽  
pp. 4
Author(s):  
Marymol Koshy ◽  
Bushra Johari ◽  
Mohd Farhan Hamdan ◽  
Mohammad Hanafiah
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Magnetic Resonance ◽  
Genetic Disorder ◽  
Familial Hypertrophic Cardiomyopathy ◽  
Non Invasive ◽  
Wide Range ◽  
Proper Diagnosis ◽  
Magnetic Resonance Imaging Mri ◽  
Potential Use

Hypertrophic cardiomyopathy (HCM) is a global disease affecting people of various ethnic origins and both genders. HCM is a genetic disorder with a wide range of symptoms, including the catastrophic presentation of sudden cardiac death. Proper diagnosis and treatment of this disorder can relieve symptoms and prolong life. Non-invasive imaging is essential in diagnosing HCM. We present a review to deliberate the potential use of cardiac magnetic resonance (CMR) imaging in HCM assessment and also identify the risk factors entailed with risk stratification of HCM based on Magnetic Resonance Imaging (MRI).

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