scholarly journals Determination of cyanide in bamboo shoots by microdiffusion combined with ion chromatography–pulsed amperometric detection

2018 ◽  
Vol 5 (4) ◽  
pp. 172128 ◽  
Author(s):  
Ming Ding ◽  
Kailiang Wang
Keyword(s):  
Ion Chromatography ◽  
Limit Of Detection ◽  
Correlation Coefficients ◽  
Amperometric Detection ◽  
High Sensitivity ◽  
Practical Method ◽  
Pulsed Amperometric Detection ◽  
Bamboo Shoots ◽  
Relative Standard

A practical method for the determination of cyanide in bamboo shoots has been developed using microdiffusion preparation integrated with ion chromatography–pulsed amperometric detection (IC-PAD). Cyanide was released from bamboo shoots after Conway cell microdiffusion, and then analysed by IC-PAD. In comparison with the previously reported methods, derivatization and ion-pairing agent addition were not required in this proposed microdiffusion combined with IC-PAD method. The microdiffusion parameters were optimized including hydrolysis systems, temperature, time, and so on. Under the optimum conditions, the linear range of the calibration curve for cyanide was 0.2–200.0 µg kg −1 with satisfactory correlation coefficients of 0.9996 and the limit of detection was 0.2 µg kg −1 ( S/N  = 3). The spiked recovery range was from 92.8 to 98.6%. The intra-day and inter-day relative standard deviations of cyanide were 2.7–14.9% and 3.0–18.3%, respectively. This method was proved to be convenient in operation with high sensitivity, precision and accuracy, and was successfully applied in the determination of cyanide in bamboo shoot samples.

scholarly journals Spectrophotometric determination of Phenylephrine hydrochloride and Salbutamol sulphate drugs in pharmaceutical preparations using diazotized Metoclopramide hydrochloride

2015 ◽  
Vol 12 (1) ◽  
pp. 167-177 ◽  
Author(s):  
Baghdad Science Journal
Keyword(s):  
Limit Of Detection ◽  
Pharmaceutical Preparations ◽  
Correlation Coefficients ◽  
Limit Of Quantification ◽  
Pharmaceutical Dosage Forms ◽  
Salbutamol Sulphate ◽  
Phenylephrine Hydrochloride ◽  
Relative Standard ◽  
Metoclopramide Hydrochloride

A spectrophotometric method has been proposed for the determination of two drugs containing phenol group [phenylephrine hydrochloride (PHP) and salbutamol sulphate (SLB)] in pharmaceutical dosage forms. The method is based on the diazotization reaction of metoclopramide hydrochloride (MCP) and coupling of the diazotized reagent with drugs in alkaline medium to give intense orange colored product (?max at 470 nm for each of PHP and SLB). Variable parameters such as temperature, reaction time and concentration of the reactants have been analyzed and optimized. Under the proposed optimum condition, Beer’s law was obeyed in the concentration range of 1-32 and 1-14 ?g mL-1 for PHP and SLB, respectively. The limit of detection (LOD) and limit of quantification (LOQ) for each of PHP and SLB were 0.60, 0.52 ?g mL-1 and 2.02, 1.72 ?g mL-1, respectively. No interference was observed from common excipients present in pharmaceutical preparations. The good correlation coefficients and low relative standard deviation assert the applicability of this method. The suggested method was further applied for the determinations of drugs in commercial pharmaceutical preparations, which was compared statistically with reference methods by means of t- test and F- test and were found not to differ significantly at 95% confidence level. The procedure was characterized by its simplicity with accuracy and precision.

scholarly journals Derivatization Ion Chromatography for the Determination of Monoethanolamine in Presence of Hydrazine in PHWR Steam-Water Circuits

2011 ◽  
Vol 2011 ◽  
pp. 1-5
Author(s):  
Ayushi D. ◽  
Arijit Sengupta ◽  
Sangita D. Kumar ◽  
A. G. Kumbhar ◽  
G. Venkateswaran
Keyword(s):  
Ion Chromatography ◽  
Mobile Phase ◽  
Limit Of Detection ◽  
Accurate Method ◽  
Feed Water ◽  
Relative Standard ◽  
Conductometric Detection ◽  
Mode A ◽  
Eluent Acetone

A simple, rapid and accurate method for the determination of monoethanolamine (MEA) in PHWR steam-water circuits has been developed. MEA is added in the feed water to provide protection against corrosion while hydrazine is added to scavenge dissolved oxygen. The quantitative determination of MEA in presence of hydrazine was accomplished using derivatization ion chromatography with conductometric detection in nonsuppressed mode. A Metrosep cation 1-2 analytical column and a Metrosep cartridge were used for cation separation. A mixture of 4 mM tartaric acid, 20% acetone and 0.05 mM HNO3was used as eluent. Acetone in the mobile phase leads to the formation of different derivatives with MEA and hydrazine. The interferences due Na+and NH4 +were eliminated by adopting a simple pretreatment procedure employing OnGuard-H cartridge. The limit of detection limit of MEA was 0.1 μg mL−1and the relative standard deviation was 2% for the overall method. The recovery of MEA added was in the range 95%–102%. The method was applied to the determination of MEA in steam generator water samples.

scholarly journals Development of an Analytical Protocol for Determination of Cyanide in Human Biological Samples Based on Application of Ion Chromatography with Pulsed Amperometric Detection

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Ewa Jaszczak ◽  
Marek Ruman ◽  
Sylwia Narkowicz ◽  
Jacek Namieśnik ◽  
Żaneta Polkowska
Keyword(s):  
Ion Chromatography ◽  
Biological Samples ◽  
Amperometric Detection ◽  
Sample Pretreatment ◽  
Cyanide Ion ◽  
Pulsed Amperometric Detection ◽  
Analytical Protocol ◽  
Good Repeatability ◽  
Optimized Conditions

A simple and accurate ion chromatography (IC) method with pulsed amperometric detection (PAD) was proposed for the determination of cyanide ion in urine, sweat, and saliva samples. The sample pretreatment relies on alkaline digestion and application of Dionex OnGuard II H cartridge. Under the optimized conditions, the method showed good linearity in the range of 1–100 μg/L for urine, 5–100 μg/L for saliva, and 3–100 μg/L for sweat samples with determination coefficients (R)>0.992. Low detection limits (LODs) in the range of 1.8 μg/L, 5.1 μg/L, and 5.8 μg/L for urine, saliva, and sweat samples, respectively, and good repeatability (CV < 3%, n=3) were obtained. The proposed method has been successfully applied to the analysis of human biological samples.

A flexible ion chromatography column-switching system with a switching time window (STW) calibration program for the determination of myo-inositol in infant formula by pulsed amperometric detection

2015 ◽  
Vol 7 (6) ◽  
pp. 2830-2838 ◽  
Author(s):  
Shuifeng Zhang ◽  
Liying Huang ◽  
Hongyan Li ◽  
Xiaozhen Chen ◽  
Fengli Wang ◽  
...  
Keyword(s):  
Infant Formula ◽  
Ion Chromatography ◽  
Switching Time ◽  
Time Window ◽  
Amperometric Detection ◽  
Column Switching ◽  
Switching System ◽  
Pulsed Amperometric Detection ◽  
Calibration Program

The column-switching system allows for convenient determination and calibration of STW parameters.

scholarly journals Determinación de F-, CL-, NO3- y SO42- en muestras de agua, por cromatografía iónica y métodos tradicionales

2017 ◽  
Vol 2 (2) ◽  
pp. 39
Author(s):  
Danis Pirela ◽  
Gleidy Vivas ◽  
Ligbel Sánchez ◽  
Hendrik Avila
Keyword(s):  
Ion Chromatography ◽  
Limit Of Detection ◽  
Comparison Of Methods ◽  
Chromatography Method ◽  
Sulfate Ions ◽  
Palabras Clave ◽  
Relative Standard ◽  
Scientific Technical ◽  
Chloride Sulfate

RESUMEN El análisis químico debe generar resultados correctos y confiables, siendo importante la validación del método para la realización de servicios científicos técnicos, con calidad de los resultados. Se determinó la concentración de los F-, Cl-, NO3- y SO42- por métodos tradicionales y cromatografía iónica. Se evaluó la precisión en término de repetibilidad y la exactitud en porcentaje de recuperación utilizando patrones certificados. Se obtuvieron desviaciones estándar relativas en un intervalo de 0,70 a 4% y porcentajes de recuperación entre 98 y 99% para el análisis por cromatografía iónica. El límite de detección para el método de cromatografía iónica se encontró entre 0,005 y 0,1391 mg/L y mostró una linealidad de 0,999. Los resultados demuestran que el método de cromatografía iónica es más sensible y rápido al ser comparado con los métodos tradicionales, con comportamientos similares para la determinación de los iones de fluoruro y sulfato, pero diferentes en la determinación de los iones de cloruro y nitrato. Palabras clave: Cromatografía iónica, fluoruro, cloruro, sulfato, nitrato, comparación de métodos. ABSTRACT Chemical analysis must generate correct and reliable results, method validation for scientific-technical services with quality results, to be important. Comparing the results obtained by traditional methods and ion chromatography in the determination of F-, Cl-, NO3- and SO42-- was conducted. Was evaluated in terms of repeatability precision and for accuracy tests of recovery using certified patterns were carried out. Relative standard deviations in a range from 0.70 to 4% and recovery rates between 98 and 99% for analysis by ion chromatography were. The limit of detection for ion chromatography method was found between 0.005 and 0.1391 mg/L and showed a linearity of 0.999. The results show that the ion chromatography method is more sensitive and faster when compared with the methods traditional, with similar behaviors for the determination of fluoride and sulfate ions, but different in the determination of the chloride and nitrate ions. Key words: Ion chromatography, fluoride, chloride, sulfate, nitrate, comparison of methods

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