scholarly journals Eco-friendly methoximation of aromatic aldehydes and ketones using MnCl 2 .4H 2 O as an easily accessible and efficient catalyst

2021 ◽  
Vol 8 (7) ◽  
pp. 210142
Author(s):  
Melina C. Ontivero ◽  
Teodoro S. Kaufman ◽  
Iván Cortés ◽  
Andrea B. J. Bracca
Keyword(s):  
Efficient Method ◽  
Environmentally Friendly ◽  
Aromatic Aldehydes ◽  
Fine Chemicals ◽  
Efficient Catalyst ◽  
Mild Conditions ◽  
Aldehydes And Ketones

Methoximes are important as a class of intermediates and products, among fine chemicals and specialties. The development of a new, facile and efficient method for their synthesis is reported. The methoximes were properly accessed from the corresponding aromatic aldehydes and ketones in good to excellent yields, under mild conditions, employing the inexpensive and environmentally friendly MnCl 2 .4H 2 O as a catalyst (at low loading and without the addition of ligand), in EtOH at 50°C. The scope of the process was systematically assessed.

p-Toluenesulfonic Acid Coated Natural Phosphate as an Efficient Catalyst for the Synthesis of 2-Substituted Benzimidazole

2018 ◽  
Vol 42 (12) ◽  
pp. 614-617
Author(s):  
Soumia Belkharchach ◽  
Hanane Elayadi ◽  
Hana Ighachane ◽  
Said Sebti ◽  
Mustapha Ait Ali ◽  
...  
Keyword(s):  
Environmentally Friendly ◽  
Catalytic Amount ◽  
Reusable Catalyst ◽  
Efficient Catalyst ◽  
Natural Phosphate ◽  
Mild Conditions ◽  
Toluenesulfonic Acid ◽  
High Yields

2-Substituted benzimidazoles are selectively synthesised in high yields via the condensation of o-phenylenediamine derivatives with aldehyde derivatives using catalytic amount of p-toluenesulfonic acid coated natural phosphate (NP/PTSA) under mild conditions. The use of NP/PTSA as a reusable catalyst makes this process simple, convenient, and environmentally friendly.

Decarboxylative Umpolung Synthesis of Amines from Carbonyl Compounds

Synlett ◽  
2020 ◽  
Vol 31 (16) ◽  
pp. 1543-1550
Author(s):  
Baoguo Zhao ◽  
Wen-Wen Chen
Keyword(s):  
Carbonyl Compounds ◽  
Aromatic Aldehydes ◽  
High Reactivity ◽  
Mild Conditions ◽  
Intramolecular Reaction ◽  
Unsaturated Aldehydes ◽  
Recent Advances ◽  
Intermolecular Reaction ◽  
Aldehydes And Ketones

2-Azaallyl anions are valuable intermediates which have versatile applications in functionalization with various electrophiles. Decarboxylation of the imines formed from aromatic aldehydes and α,α-diphenylglycine provides an interesting and efficient way to generate delocalized 2-azaallyl anions, which display high reactivity toward different electrophiles with excellent regioselectivity at the diphenylketimino aryl carbon of the 2-azaallyl anions. The transformation produces various amines in good yields under very mild conditions. This Synpacts article highlights the recent advances on the decarboxylative umpolung synthesis of amines from carbonyl compounds.1 Introduction2 Decarboxylative Umpolung Reactions of Carbonyl Compounds with Different Electrophiles2.1 Reaction with π-Allyl–Pd(II) Species2.2 Reaction with Morita–Baylis–Hillman Adducts2.3 Reaction with Imines2.3.1 Intermolecular Reaction with N-Ts Imines2.3.2 Intramolecular Reaction with Chiral N-tert-Butanesulfinyl Imines2.4 Reaction with Aldehydes and Ketones3 Decarboxylative Umpolung Reaction of α,β-Unsaturated Aldehydes with Aldehydes4 Conclusion

DMAP as a new efficient catalyst for the one-pot synthesis of condensed phthalazines

2017 ◽  
Vol 72 (5) ◽  
pp. 361-368 ◽  
Author(s):  
Esma Lamera ◽  
Sofiane Bouacida ◽  
Hocine Merazig ◽  
Aissa Chibani ◽  
Marc Le Borgne ◽  
...  
Keyword(s):  
Environmental Pollution ◽  
Efficient Method ◽  
Toxic Metals ◽  
Aromatic Aldehydes ◽  
One Pot ◽  
Efficient Catalyst ◽  
One Pot Synthesis ◽  
The One ◽  
The Cost ◽  
Work Up

AbstractA new, convenient, and efficient method for the synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones is developed starting from phthalhydrazide, aromatic aldehydes, and malononitrile using 4-N,N-dimethylaminopyridin as catalyst. This modified route provides much higher yields and a simple work-up procedure of products. Also this methodology is of interest due to the use of ethanol as a solvent without use of any toxic metals as catalyst, thus minimizing the cost, the operational hazards, and environmental pollution.

Eco-Friendly Synthesis of 2-Substituted Benzimidazoles Using Air as the Oxidant

2013 ◽  
Vol 66 (2) ◽  
pp. 262 ◽  
Author(s):  
Guo-Feng Chen ◽  
Hai-Dong Shen ◽  
Hui-Ming Jia ◽  
Li-Yan Zhang ◽  
Hong-Yan Kang ◽  
...  
Keyword(s):  
Room Temperature ◽  
Environmentally Friendly ◽  
Aromatic Aldehydes ◽  
Absolute Ethanol ◽  
One Pot ◽  
Mild Conditions ◽  
One Pot Condensation ◽  
The One

A simple, environmentally friendly procedure for the synthesis of 2-substituted benzimidazoles by the one-pot condensation of o-phenylenediamines with aromatic aldehydes using continuous bubbling of air in absolute ethanol at room temperature is described. The simplicity of the system, mild conditions, involvement of a non-toxic and practically inexhaustible oxidant, easy and quick isolation of the products, and moderate to good yields are the main advantages of this procedure.

Highly dispersed ultrafine palladium nanoparticles encapsulated in a triazinyl functionalized porous organic polymer as a highly efficient catalyst for transfer hydrogenation of aldehydes

2018 ◽  
Vol 6 (37) ◽  
pp. 18242-18251 ◽  
Author(s):  
Jin Yang ◽  
Man Yuan ◽  
Dan Xu ◽  
Hong Zhao ◽  
Yangyang Zhu ◽  
...  
Keyword(s):  
Palladium Nanoparticles ◽  
Catalytic Reduction ◽  
Aromatic Aldehydes ◽  
Transfer Hydrogenation ◽  
Organic Polymer ◽  
Efficient Catalyst ◽  
Porous Organic Polymer ◽  
Mild Conditions ◽  
Highly Dispersed ◽  
Organic Pores

A stable Pd@TP-POP catalyst with highly dispersed ultrafine Pd NPs confined in its organic pores was fabricated for catalytic reduction of 4-nitrophenol and transfer hydrogenation of aromatic aldehydes under very mild conditions.

Main group metal–ligand cooperation of N-heterocyclic germylene: an efficient catalyst for hydroboration of carbonyl compounds

2016 ◽  
Vol 52 (95) ◽  
pp. 13799-13802 ◽  
Author(s):  
Yile Wu ◽  
Changkai Shan ◽  
Ying Sun ◽  
Peng Chen ◽  
Jianxi Ying ◽  
...  
Keyword(s):  
Carbonyl Compounds ◽  
Main Group ◽  
Efficient Catalyst ◽  
Mild Conditions ◽  
Group Metal ◽  
Main Group Metal ◽  
Aldehydes And Ketones ◽  
Substrate Tolerance ◽  
Metal Ligand ◽  
Operational Simplicity

N-heterocyclic ylide-like germylene effectively promotes the hydroboration of aldehydes and ketones under mild conditions with broad substrate tolerance, operational simplicity of the procedure and excellent yields.

Efficient method for the preparation of pinacols derived from aromatic and aliphatic ketones by using low-valent titanium reagents in dichloromethane-pivalonitrile

2000 ◽  
Vol 78 (6) ◽  
pp. 657-665 ◽  
Author(s):  
Akifumi Kagayama ◽  
Koji Igarashi ◽  
Teruaki Mukaiyama
Keyword(s):  
Carbonyl Group ◽  
Efficient Method ◽  
Steric Effect ◽  
Coupling Reaction ◽  
Reductive Coupling ◽  
Mild Conditions ◽  
Aliphatic Ketones ◽  
Aldehydes And Ketones ◽  
High Yields ◽  
Selective Formation

The reductive coupling reaction of aldehydes and ketones, including unsymmetrical aliphatic ketones, proceeded smoothly to give the corresponding pinacols in good to high yields under mild conditions by using combination of titanium(II) chloride and zinc or titanium(IV) chloride and zinc in dichloromethane-pivalonitrile. Meso-selective formation of the coupling products was observed in the cases of some aliphatic ketones. The diastereoselectivities of coupling products depend on both difference of bulkiness of 2-, and 2'-substituents of carbonyl group of the reactant, and overall steric effect around the carbonyl groups.Key words: diastereoselective pinacol reaction, dichloromethane-pivalonitrile, titanium(II) chloride, titanium(IV) chloride, zinc.

Chiral Mn(III) Salen Complex Immobilized on CuFe2O4@SiO2-NH2 NPs: A Cheap and Efficient Catalyst for N-arylation of Aryl Halides and Phenylboronic Acid Under Mild Conditions

2020 ◽  
Vol 17 (11) ◽  
pp. 857-863
Author(s):  
Mohammad Ali Nasseri ◽  
Seyyedeh Ameneh Alavi ◽  
Milad Kazemnejadi ◽  
Ali Allahresani
Keyword(s):  
Phenylboronic Acid ◽  
Significant Loss ◽  
Aryl Halides ◽  
Coupling Reactions ◽  
Efficient Catalyst ◽  
Aryl Chlorides ◽  
Mild Conditions ◽  
Cross Coupling Reactions ◽  
Salen Complex ◽  
Ft Ir

A convenient and efficient chiral CuFe2O4@SiO2-Mn(III) Ch.salen nanocatalyst has been developed for the C-N cross-coupling reactions of aryl halides/ phenylboronic acid with N-heterocyclic compounds in water and/or DMSO under mild conditions. The catalyst could be applied for the N-arylation of a variety of nitrogen-containing heterocycles with aryl chlorides, bromides, iodides and phenylboronic acid under mild conditions. Moderate to good yields were achieved for all substrates. The structure of catalyst was characterized using various techniques including FT-IR, FE-SEM, EDX, XRD, TEM and TGA. The catalyst can be simply recovered and reused for several times without significant loss of activity.

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