Observations on the physiology of the nerves of sensation, illustrated by a case of paralysis of the fifth pair
The influence of the fifth pair of nerves on the functions of sight, smell, and taste, is a subject which has lately occupied the attention of physiologists. Many experiments have been made on living animals with a view to its elucidation; but these experiments have never led to any satisfactory conclusion. Considerable light has been thrown upon this obscure question by the phenomena attending a case of paralysis of the fifth pair of nerves, which occurred in the author’s practice, and of which he gives the history in detail, after quoting the account given by Magendie of his experiments and speculations respecting the functions of these nerves. The lady who was the subject of these observations had been affected with total insensibility of the left side of the face and head, together with strabismus, accompanied with double vision; but the powers of voluntary motion of all these parts remained entire. The globe of the left eye was quite insensible to touch, though it retained the power of vision unimpaired, excepting that for sometime previous to death it had lost the faculty of distinguishing colours. The left nostril received no impressions from the most irritating stimulants, such as snuff or ammonia; yet the sense of smelling continued unimpaired. The left side of the tongue was quite insensible to impressions both of touch and of taste. On examining the brain after death, a scirrhous tumour was found lying on the inner surface of the sphenoid bone, extending laterally to the foramen auditorium internum, and resting posteriorly on the pons Varolii, which was slightly ulcerated. The tumour had completely obliterated the foramina for the exit of the three branches of the fifth pair of nerves. This case proves, therefore, that, contrary to the opinion of Magendie, the senses of smell and vision can be exercised independently of the fifth pair of nerves; and that the sense of taste is altogether derived from that nerve; and corroborates the views of Sir Charles Bell on this part of physiology.