III. Some remarks on the physiological action of the Tanghinia venenifera

1859 ◽  
Vol 9 ◽  
pp. 173-174

The famous poison-tree of Madagascar was described for the first, time by Aubert du Petit Thouars in his ‘Genera Madagascarensia,’ under the name of Tanghinia venenifera . At a later period, Sir W. Hooker published a good description, with a figure of this tree, named by him Cerbera Tanghin (see Botanical Magazine, pi. 2968), so that nothing is wanted with regard to the botanical knowledge of this plant. On the other hand, the physiological effects of its poisonous parts have not been hitherto investigated. All we know is, that the fruit of the Tanghinia is a strong poison, and is used in Madagascar as an ordeal poison in the most strange and revolting way. The only experiment on animals made by Ollivier, showed that 12 grains kill a dog in some hours, but this experiment gave no further in­ sight into the real action of the Tanghinia. We hope, therefore, that the Royal Society will take some interest in the experiments which we undertook with this poison, of which the following is a short abstract. The poison used by us was the alcoholic extract of the leaves and small stems of the Tanghinia, prepared from dried specimens, which Prof. Pelikan had received from Count Seyderitz of Mecklenburg. About one centigram of this extract was sufficient to show the full effect of the poison on frogs, when introduced into a wound of the back. It acted also when given by the mouth, but in this case a somewhat larger dose was required to produce a full effect.

1894 ◽  
Vol 55 (331-335) ◽  
pp. 16-17

Both branches of the science of demography—natality statistics as well as mortality statistics—originated on British soil. It was in 1665 that the Royal Society published the first work on these matters (Graunt’s “Observations”), whilst in 1693 Halley, by establishing the first life table, laid the foundation of the scientific treatment of mortality statistics. These tables of mortality showed for the first time how to measure the probability of death for each year of human age. The other branch of vital statistics is still in want of a corresponding table of natality, showing the probability of birth for each of the age-combinations of the parents.


In 1947 a sub-committee of the Library Committee was appointed to take charge of the arrangements for the celebration of the tercentenary of the Society’s foundation. The sub-committee proceeded to consider the ways in which the tercentenary could most fittingly be celebrated, and in the course of their deliberations had brought to their attention the question of the arrangement and cataloguing of the Society’s archives and manuscripts. Upon investigation, it was found that the collections were in a state of considerable disorder, and that the task of arranging and cataloguing them would occupy the undivided attention of an assistant for a period of some years. Unfortunately, the expenditure necessary to carry out such a project was more than the Society could at that time support, and it appeared for a while that the scheme would fail for lack of funds. In November 1949, however, the Pilgrim Trust generously made a grant to the Society sufficient to cover the expenses of the scheme for a period of three years, and, an assistant having been appointed, work began in January 1950. By February 1952 the progress which had been made was so encouraging that the Pilgrim Trust agreed to make a further contribution, to enable the Society to continue the work so promisingly begun. While it would be too much to say that the cataloguing is now complete, it is certainly true that the collections are now better arranged and more accessible than they have, in all probability, ever been before; and it was therefore decided that Mr Bluhm, the assistant who has been employed on the scheme since its inception, should draw up a general guide to the archives and other manuscripts, in which the contents of the collections should be summarized, and the work done by himself related to that done by previous cataloguers. I am sure that Fellows will be glad of this opportunity of reading Mr Bluhm’s report in Notes and Records and to see the progress that has been made thanks to the generosity of the Pilgrim Trust. Now that our archives and manuscripts have been put in order and catalogued, owners of documents relating to the Society or its Fellows may be encouraged to deposit them in the Library for reference and safe keeping. I. Introductory remarks 1. The purpose of this Guide is to provide a general summary of the Society’s archives and the other MSS in its possession, to show in what manner they are catalogued, and what form the catalogues take. As far as the writer is aware, this is the first time that any such Guide has been prepared ; excellent catalogues have been made of the various series of guardbooks which contain the greater part of the archives of the 17th and 18th centuries, but:— (a) no attempt has hitherto been made to give any account of the 19th century archives, and these are in a much more complicated state than those from earlier centuries; (b) the attention of previous cataloguers has been directed for the most part to the official correspondence and papers of the Society. However, much other interesting manuscript material has been acquired from time to time, and it is desirable that some account of this should also be given.


2004 ◽  
Vol 31 (1) ◽  
pp. 6-29 ◽  
Author(s):  
Richard L. Hodgkinson ◽  
John E. Whittaker

ABSTRACT: In spite of his many other interests, Edward Heron-Allen also worked for nearly 50 years as a scientist on minute shelled protists, called foraminifera, much of it in an unpaid, unofficial capacity at The Natural History Museum, London, and notably in collaboration with Arthur Earland. During this career he published more than 70 papers and obtained several fellowships, culminating in 1919 in his election to the Royal Society. Subsequently, he bequeathed his foraminiferal collections and fine library to the Museum, and both are housed today in a room named in his honour. In this paper, for the first time, an assessment of his scientific accomplishments is given, together with a full annotated bibliography of his publications held in the Heron-Allen Library. This is part of a project to produce a bibliography of his complete publications, recently initiated by the Heron-Allen Society.


2012 ◽  
Vol 39 (2) ◽  
pp. 217-233 ◽  
Author(s):  
J. David Archibald

Studies of the origin and diversification of major groups of plants and animals are contentious topics in current evolutionary biology. This includes the study of the timing and relationships of the two major clades of extant mammals – marsupials and placentals. Molecular studies concerned with marsupial and placental origin and diversification can be at odds with the fossil record. Such studies are, however, not a recent phenomenon. Over 150 years ago Charles Darwin weighed two alternative views on the origin of marsupials and placentals. Less than a year after the publication of On the origin of species, Darwin outlined these in a letter to Charles Lyell dated 23 September 1860. The letter concluded with two competing phylogenetic diagrams. One showed marsupials as ancestral to both living marsupials and placentals, whereas the other showed a non-marsupial, non-placental as being ancestral to both living marsupials and placentals. These two diagrams are published here for the first time. These are the only such competing phylogenetic diagrams that Darwin is known to have produced. In addition to examining the question of mammalian origins in this letter and in other manuscript notes discussed here, Darwin confronted the broader issue as to whether major groups of animals had a single origin (monophyly) or were the result of “continuous creation” as advocated for some groups by Richard Owen. Charles Lyell had held similar views to those of Owen, but it is clear from correspondence with Darwin that he was beginning to accept the idea of monophyly of major groups.


2018 ◽  
Vol 52 (2) ◽  
pp. 455-462 ◽  
Author(s):  
G. Ya. Doroshina ◽  
I. A. Nikolajev

Sphagnum mires on the Greater Caucasus are rare, characterized by the presence of relict plant communities of glacial age and are in a stage of degradation. The study of Sphagnum of Chefandzar and Masota mires is carried out for the first time. Seven species of Sphagnum are recorded. Their distribution and frequency within the North Caucasus are analyzed. Sphagnum contortum, S. platyphyllum, S. russowii, S. squarrosum are recorded for the first time for the study area and for the flora of North Ossetia. The other mosses found in the study area are listed.


2018 ◽  
Author(s):  
Amir Forouharfar

The paper was shaped around the pivotal question: Is SE a sound and scientific field of research? The question has given a critical tone to the paper and has also helped to bring out some of the controversial debates in the realm of SE. The paper was organized under five main discussions to be able to provide a scientific answer to the research question: (1)<b> </b>is “social entrepreneurship” an oxymoron?, (2) the characteristics of SE knowledge, (3) sources of social entrepreneurship knowledge, (4) SE knowledge: structure and limitations and (5) contributing epistemology-making concepts for SE.<b> </b>Based on the sections,<b> </b>the study relied on the relevant philosophical schools of thought in <i>Epistemology </i>(e.g. <i>Empiricism</i>, <i>Rationalism</i>, <i>Skepticism</i>, <i>Internalism</i> vs. <i>Externalism</i>,<i> Essentialism, Social Constructivism</i>, <i>Social Epistemology, etc.</i>) to discuss these controversies around SE and proposes some solutions by reviewing SE literature. Also, to determine the governing linguistic discourse in the realm of SE, which was necessary for our discussion,<i> Corpus of Contemporary American English (COCA)</i> for the first time in SE studies was used. Further, through the study, SE buzzwords which constitute SE terminology were derived and introduced to help us narrowing down and converging the thoughts in this field and demarking the epistemological boundaries of SE. The originality of the paper on one hand lies in its pioneering discussions on SE epistemology and on the other hand in paving the way for a construction of sound epistemology for SE; therefore in many cases after preparing the philosophical ground for the discussions, it went beyond the prevalent SE literature through meta-analysis to discuss the cases which were raised. The results of the study verified previously claimed embryonic pre-paradigmatic phase in SE which was far from a sound and scientific knowledge, although the scholarly endeavors are the harbingers of such a possibility in the future which calls for further mature academic discussion and development of SE knowledge by the SE academia.


Author(s):  
Caroline Durand

Al-Qusayr is located 40 km south of modern al-Wajh, roughly 7 km from the eastern Red Sea shore. This site is known since the mid-19th century, when the explorer R. Burton described it for the first time, in particular the remains of a monumental building so-called al-Qasr. In March 2016, a new survey of the site was undertaken by the al-‘Ula–al-Wajh Survey Project. This survey focused not only on al-Qasr but also on the surrounding site corresponding to the ancient settlement. A surface collection of pottery sherds revealed a striking combination of Mediterranean and Egyptian imports on one hand, and of Nabataean productions on the other hand. This material is particularly homogeneous on the chronological point of view, suggesting a rather limited occupation period for the site. Attesting contacts between Mediterranean merchants, Roman Egypt and the Nabataean kingdom, these new data allow a complete reassessment of the importance of this locality in the Red Sea trade routes during antiquity.


2016 ◽  
Vol 1 (1) ◽  
Author(s):  
D.G. Shah ◽  
D.N. Mehta ◽  
R.V. Gujar

Bryophytes are the second largest group of land plants and are also known as the amphibians of the plant kingdom. 67 species of bryophytes have been reported from select locations across the state of Gujrat. The status of family fissidentaceae which is a large moss family is being presented in this paper. Globally the family consists of 10 genera but only one genus, Fissidens Hedw. has been collected from Gujarat. Fissidens is characterized by a unique leaf structure and shows the presence of three distinct lamina, the dorsal, the ventral and the vaginant lamina. A total of 8 species of Fissidens have been reported from the state based on vegetative characters as no sporophyte stages were collected earlier. Species reported from the neighboring states also showed the absence of sporophytes. The identification of different species was difficult due to substantial overlap in vegetative characters. Hence a detailed study on the diversity of members of Fissidentaceae in Gujarat was carried out between November 2013 and February 2015. In present study 8 distinct species of Fissidens have been collected from different parts of the state. Three species Fissidens splachnobryoides Broth., Fissidens zollingerii Mont. and Fissidens curvato-involutus Dixon. have been identified while the other five are still to be identified. Fissidens zollingerii Mont. and Fissidens xiphoides M. Fleisch., which have been reported as distinct species are actually synonyms according to TROPICOS database. The presence of sexual reproductive structures and sporophytes for several Fissidens species are also being reported for the first time from the state.


2021 ◽  
Vol 9 (5) ◽  
pp. 951
Author(s):  
Hazrat Bilal ◽  
Gaojian Zhang ◽  
Tayyab Rehman ◽  
Jianxion Han ◽  
Sabir Khan ◽  
...  

The New Delhi Metallo-β-lactamase (NDM) is among the most threatening forms of carbapenemases produced by K. pneumoniae, well-known to cause severe worldwide infections. The molecular epidemiology of blaNDM-1-harboring K. pneumoniae is not well elucidated in Pakistan. Herein, we aim to determine the antibiotics-resistance profile, genes type, molecular type, and plasmid analysis of 125 clinically isolated K. pneumoniae strains from urine samples during July 2018 to January 2019 in Pakistan. A total of 34 (27.2%) K. pneumoniae isolates were carbapenemases producers, and 23 (18.4%) harbored the blaNDM-1 gene. The other carbapenemases encoding genes, i.e., blaIMP-1 (7.2%), blaVIM-1 (3.2%), and blaOXA-48 (2.4%) were also detected. The Multi Locus Sequence Typing (MLST) results revealed that all blaNDM-1-harboring isolates were ST11. The other sequence types detected were ST1, ST37, and ST105. The cluster analysis of Xbal Pulsed Field Gel Electrophoresis (PFGE) revealed variation amongst the clusters of the identical sequence type isolates. The blaNDM-1 gene in all of the isolates was located on a 45-kb IncX3 plasmid, successfully transconjugated. For the first time, blaNDM-1-bearing IncX3 plasmids were identified from Pakistan, and this might be a new primary vehicle for disseminating blaNDM-1 in Enterobacteriaceae as it has a high rate of transferability.


The barometer, here alluded to, may in some measure be consi­dered as two separate and independent barometers, inasmuch as it is formed of two distinct tubes dipping into one and the same cistern of mercury. One of these tubes is made of flint glass, and the other of crown glass, with a view to ascertain whether, at the end of any given period, the one may have had any greater chemical effect on the mercury than the other, and thus affected the results. A brass rod, to which the scale is attached, passes through the framework, between the two tubes, and is thus common to both : one end of which is furnished with a fine agate point, which, by means of a rack and pinion moving the whole rod, may be brought just to touch the surface of the mercury in the cistern, the slightest contact with which is immediately discernible; and the other end of which bears the usual scale of inches, tenths, &c.; and there is a separate vernier for each tube. A small thermometer, the bulb of which dips into the mercury in the cistern, is inserted at the bottom : and an eye­piece is also there fixed, so that the agate point can be viewed with more distinctness and accuracy. The whole instrument is made to turn round in azimuth, in order to verify the perpendicularity of the tubes and the scale. It is evident that there are many advantages attending this mode of construction, which are not to be found in the barometers as usu­ally formed for general use in this country. The absolute heights are more correctly and more satisfactorily determined ; and the per­manency of true action is more effectually noticed and secured. For, every part is under the inspection and control of the observer; and any derangement or imperfection in either of the tubes is imme­diately detected on comparison with the other. And, considering the care that has been taken in filling the tubes, and setting off the scale, it may justly be considered as a standard barometer . The pre­sent volume of the Philosophical Transactions will contain the first register of the observations that have been made with this instru­ment.


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