scholarly journals Ancient genomics

2015 ◽  
Vol 370 (1660) ◽  
pp. 20130387 ◽  
Author(s):  
Clio Der Sarkissian ◽  
Morten E. Allentoft ◽  
María C. Ávila-Arcos ◽  
Ross Barnett ◽  
Paula F. Campos ◽  
...  
Keyword(s):  
Degraded Dna ◽  
Nuclear Markers ◽  
New Era ◽  
The Past ◽  
Whole Genomes ◽  
Anatomically Modern Humans ◽  
Extensive Degradation ◽  
Sequencing Platforms ◽  
Source Materials ◽  
Analytical Power

The past decade has witnessed a revolution in ancient DNA (aDNA) research. Although the field's focus was previously limited to mitochondrial DNA and a few nuclear markers, whole genome sequences from the deep past can now be retrieved. This breakthrough is tightly connected to the massive sequence throughput of next generation sequencing platforms and the ability to target short and degraded DNA molecules. Many ancient specimens previously unsuitable for DNA analyses because of extensive degradation can now successfully be used as source materials. Additionally, the analytical power obtained by increasing the number of sequence reads to billions effectively means that contamination issues that have haunted aDNA research for decades, particularly in human studies, can now be efficiently and confidently quantified. At present, whole genomes have been sequenced from ancient anatomically modern humans, archaic hominins, ancient pathogens and megafaunal species. Those have revealed important functional and phenotypic information, as well as unexpected adaptation, migration and admixture patterns. As such, the field of aDNA has entered the new era of genomics and has provided valuable information when testing specific hypotheses related to the past.

Allegorie della libertŕ e tipologie del sacro nell'iconografia rivoluzionaria russa

2012 ◽  
pp. 57-80
Author(s):  
Dogo Dunja
Keyword(s):  
Cultural History ◽  
Russian Revolution ◽  
Symbolic System ◽  
The Past ◽  
History Of ◽  
Source Materials

Allegories of liberty and typologies of the sacred in the iconography of revolutionary Russia. Revolutionary iconography addresses a topic that crosses the field of studies of the Russian Revolution, whose scope in the past two decades has begun to investigate the cultural history of 1917, thanks to easier access to source materials that have re-emerged after the opening of the Russian archives. Above all, the essay attempts to reconstruct how three particular typologies (St. George, the Angel, Liberty) came into use in the Russian revolutionary symbolic system and underwent a metamorphosis, contributing to a phenomenon of syncretism. Such discourses can show how different political subjects – at times on opposing sides - employed a common imagery within a struggle for the conquest of the symbol.

Using Sources In History Teaching

2021 ◽  
pp. 54-67
Author(s):  
Seema S.Ojha
Keyword(s):  
Deductive Reasoning ◽  
Primary Source ◽  
Primary Sources ◽  
Historical Knowledge ◽  
History Teaching ◽  
Secondary Sources ◽  
The Past ◽  
Teaching History ◽  
The World ◽  
Source Materials

History is constructed by people who study the past. It is created through working on both primary and secondary sources that historians use to learn about people, events, and everyday life in the past. Just like detectives, historians look at clues, sift through evidence, and make their own interpretations. Historical knowledge is, therefore, the outcome of a process of enquiry. During last century, the teaching of history has changed considerably. The use of sources, viz. textual, visual, and oral, in school classrooms in many parts of the world has already become an essential part of teaching history. However, in India, it is only a recent phenomenon. Introducing students to primary sources and making them a regular part of classroom lessons help students develop critical thinking and deductive reasoning skills. These will be useful throughout their lives. This paper highlights the benefits of using primary source materials in a history classroom and provides the teacher, with practical suggestions and examples of how to do this.

scholarly journals Personalized Medicine in Cancer

2015 ◽  
Vol 32 (3) ◽  
pp. 153-163
Author(s):  
Md Mizanur Rahman
Keyword(s):  
Personalized Medicine ◽  
Single Gene ◽  
Biomedical Science ◽  
Practical Application ◽  
Molecular Alteration ◽  
New Era ◽  
Patients With Cancer ◽  
The Past ◽  
Molecular Aspects

Current and emerging biomedical science efforts are driven by determining how to improve clini-cal outcomes for patients. High-throughput tech-nology has revolutionized the area of transla-tional research, confirming the high complexity and heterogeneity of common diseases, partic-ularly cancer. Therefore, moving from ‘classic’ single-gene-based molecular investigation to molecular network research might result in dis-covering clinical implications faster and more efficiently .Molecular characterization of tumour cells enables refinement of classifications for many cancers and can sometimes guide treatment. Malignant diseases are no longer classified only by tumour site and histology but are separated into various homogenous molecular subtypes, distinguished by a presumed key molecular alteration. Therapies for patients with cancer have changed gradually over the past decade, moving away from the administration of broadly acting cytotoxic drugs towards the use of more-specific therapies that are targeted to each tumour. To facilitate this shift, tests need to be developed to identify those individuals who require therapy and those who are most likely to benefit from certain therapies. In particular, tests that predict the clinical outcome for patients on the basis of the genes expressed by their tumours are likely to increasingly affect patient management, heralding a new era of personalized medicine. In this review a brief discussion on definition and molecular aspects of personalized medicine and its practical application for the management of common solid cancers are highlighted.J Bangladesh Coll Phys Surg 2014; 32: 153-163

Safety Analysis Model of DUCG Based on FMEA/FTA

2018 ◽  
Author(s):  
Zhenxu Zhou ◽  
Hao Nie ◽  
Chunling Dong ◽  
Qin Zhang
Keyword(s):  
Failure Modes ◽  
Fault Tree Analysis ◽  
Safety Analysis ◽  
Nuclear Industry ◽  
Analysis Model ◽  
Industrial Systems ◽  
The Past ◽  
Research Cycle ◽  
Dynamic Uncertain Causality Graph ◽  
Analytical Power

Failure Modes and Effects Analysis (FMEA) is a useful tool to find possible flaws, to reduce cost and to shorten research cycle in complex industrial systems. Fault Tree Analysis (FTA) has gained credibility over the past years, not only in nuclear industry, but also in other industries like aerospace, petrochemical, and weapon. Both FMEA and FTA are effective techniques in safety analysis, but there are still many uncertain factors in them that are not well addressed until now. This paper combines FMEA and FTA based on Dynamic Uncertain Causality Graph (DUCG) to solve this issue. Firstly, the FMEA model is mapped into a corresponding DUCG graph. Secondly, FTA model is mapped into a corresponding DUCG graph. Thirdly, combine the above DUCG graphs. Finally, users can modify the combined DUCG graph and calculations are made. This paper bridges the gap between FMEA and FTA by combining the two methods using DUCG. And additional modeling power and analytical power can be achieved with the advantages of the combined DUCG safety analysis model and its inference algorithm. This method can also promote the application of DUCG in the system reliability and safety analysis. An example is used to illustrate this method.

Greek Strategies of Adaptation to the Roman World: The Case of the Contests

Mnemosyne ◽  
2014 ◽  
Vol 67 (3) ◽  
pp. 423-442 ◽  
Author(s):  
Sophia Aneziri
Keyword(s):  
Roman Empire ◽  
Imperial Cult ◽  
New Era ◽  
The Past ◽  
Roman World ◽  
Imperial Power

This article examines strategies that made it possible for Greek contests and the professionals who were engaged in them to retain their identity in the Roman Empire while they adapted to the circumstances of the new era. In their efforts to preserve and to enhance existing prestige and privilege, the organizers and others who were involved in the contests attempted both to exploit the past and to establish links to the new Roman power. The consequent linking of the Imperial cult with festivals, artists, athletes, and their associations provided tools that assisted the promotion of Imperial power and ideology.

scholarly journals U źródeł polskiej terminologii logopedycznej. W kierunku badań anagnostycznych

LingVaria ◽  
2020 ◽  
pp. 267-281
Author(s):  
Ewa Horyń ◽  
Marceli Olma ◽  
Mirosław Michalik
Keyword(s):  
Speech Therapy ◽  
Speech Disorders ◽  
Scientific Discipline ◽  
Research Project ◽  
The Past ◽  
Polish Language ◽  
Source Materials

AT THE SOURCES OF POLISH LOGOPEDIC TERMINOLOGY: TOWARDS ANAGNOSTIC RESESARCH The paper is a preliminary presentation of the concept of a research project Diachronic Aspects of Polish Logopedic Terminology, carried out by members of the Department of Polish Language of the Pedagogical University in Cracow. The multiauthored study briefly characterizes the beginnings of speech therapy as an independent scientific discipline, and the directions of its development in the past 50 years. It draws attention to the deficiencies and inconsistencies in the usage and understanding of specialist terms in contemporary logopedics, while setting as the primary goal of the enterprise an attempt to standardize Polish terminology related to speech disorders. The basis for this should be the etymology of the terms in question, as well as excerpts from medical and anatomical lexicons and source materials which employ the vocabulary that became the foundation of the logopedic jargon.

scholarly journals From Intersemiotic to Intertextual – a Historical Serendipity

2019 ◽  
pp. 13-26
Author(s):  
Dalibor Kesić
Keyword(s):  
Common Denominator ◽  
New Era ◽  
The Core ◽  
The Past ◽  
Works Of Art

The term intersemiotic lies at the core of contemporary approaches to semantics, literature, translation and anthropology. At first glance, its connection with text is only intermittent. There is however a blurred area of overlapping in which texts, histories, media and works of art come together to form a dynamic palimpsest of meanings. This paper aims to examine several cases in which momentous works of the past have managed to cross the boundaries of history, nations, languages and media. Their perception and influence have not always been the same, but their common denominator is the power and faculty to exert influence beyond their time and outside their domain. From Shakespeare to Kurosawa and from Cicero to Jerome, forms of art have metamorphosed to accommodate the prevailing beliefs of different eras, condemned in some and glorified in others. Centuries have gone by, but some bygones refuse to be bygones, making one wonder what their secret ingredient is, and to what they owe their everlasting perseverance. The elaboration of this paper shows that in order for a text to be able to endure centuries and to be as topical today as it used to be it the days of yore, it has to be both emphatic with general humanity, and malleable to other media and historical contexts. Just as Galileo gave in to the court of majority and still managed to rewrite the planetary history, so the works of art yield a bit of their own ingenuity every time they undergo an intersemiotic transformation, while at the same time being reborn, revitalized and fit for a new era and a new belief.

scholarly journals Habent sua fata… ekslibris – informacje o ekslibrisach i ich kolekcjach w „Zbiorach polskich” Edwarda Chwalewika

2019 ◽  
Vol 13 ◽  
pp. 258-272
Author(s):  
Agnieszka Fluda-Krokos
Keyword(s):  
Cultural Heritage ◽  
Cultural Institutions ◽  
Cultural Products ◽  
The Past ◽  
Polish Culture ◽  
Source Of Information ◽  
Source Materials

Edward Chwalewik (1873-1956) is a very important person for Polish culture. He worked many years with books and cultural products and he collected very precious source materials. One of the results of their elaboration is the publication “Polish collections: archives, libraries, offices, galleries, museums and other collections of memorabilia of the past in the homeland and exile” (1916, 1926-1927). The priceless publication is in many cases the only source of information about the once existed collections of cultural heritage. The author, collector and exlibris expert, also included information about provenances. In a few thousand descriptions of various cultural institutions and objects, including the library, recorded ca 300 entries about exlibris – collections and individual signs of books owners. The article presents characteristics of these data and selected examples.

scholarly journals CHINESE SCULPTURE IN THE NEW ERA

2021 ◽  
Vol 17 (5) ◽  
pp. 125-135
Author(s):  
Wei Xiao
Keyword(s):  
Cultural Tradition ◽  
Social Changes ◽  
The West ◽  
New Era ◽  
The Past ◽  
The Future ◽  
National Spirit ◽  
New Challenges ◽  
Cultural Content

With the advent of a new era, universal social changes pose new challenges for the art of sculpture. In terms of cultural content and practice, sculpture needs to keep pace with time. Chinese sculpture should participate in the global processes of modern sculptural development, guided by the literary and artistic concept «do not forget the past, absorb the foreign, look into the future». Not only should it receive inspiration and stimuli for development from the West but find its voice, preserving Chinese cultural tradition and Chinese national spirit.

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