scholarly journals Identification of spatial variations in COVID-19 epidemiological data using K-Means clustering algorithm: a global perspective

Author(s):  
Viswa Chandu

Background: Discerning spatial variations of COVID-19 through quantitative analysis operating on the geographically designated datasets relating to socio-demographics and epidemiological data facilitate strategy planning in curtailing the transmission of the disease and focus on articulation of necessary interventions in an informed manner. Methods: K-means clustering was employed on the available country-specific COVID-19 epidemiological data and the influential background characteristics. Country-specific case fatality rates and the average number of people tested positive for COVID-19 per every 10,000 population in each country were derived from the WHO COVID-19 situation report 107, and were used for clustering along with the background characteristics of proportion of countrys population aged >65 years and percentage GDP spent as public health expenditure. Results: The algorithm grouped the 89 countries into cluster 1 and Cluster 2 of sizes 54 and 35, respectively. It is apparent that Americas, European countries, and Australia formed a major part of cluster 2 with high COVID-19 case fatality rate, higher proportion of countrys population tested COVID-19 positive, higher percentage of GDP spent as public health expenditure, and greater percentage of population being more than 65 years of age. Conclusion: In spite of the positive correlation between high public health expenditure (%GDP) and COVID-19 incidence, case fatality rate, the immediate task ahead of most of the low and middle income countries is to strengthen their public health systems realizing that the correlation found in this study could be spurious in light of the underreported number of cases and poor death registration.

Author(s):  
Chukwuemeka E. Etodike ◽  
◽  
Elsie C. Ekeghalu ◽  
Kelechi Johnmary Ani ◽  
Emmanuel Mutambara

The novel coronavirus is far from being over; with the case-fatality rate (CFR) hitting more than 16,500 globally as of July, there is a worry that despite the fact that the global CFR curve is showing signs of flattening, the environmental peculiarities of the third world countries may be abetting global efforts towards containing the virus. Therefore, this review x-rayed these peculiarities in the light of their current concern in public health as per their contribution to the persistent surge in CFR in most developing nations. Given that the virus is transmitted via droplets, the review focused on how the state of public and environmental challenges such as air as well as water pollution and personal hygiene could be abetting the surge in coronavirus infections and morbidity. The review revealed, among other things, that challenges associated with poor sanitary conditions, lack of potable water, unventilated environments, air pollution, and poor inter-personal hygiene are devastating challenges in the fight against the pandemic. The implication is that since these conditions are systematic in nature, it may take more than average effort and public sacrifice to checkmate the case-fatality rate of the virus in the third world. Therefore, call for studies is necessary to establish empiricism for CFR patterns and ratio across areas in deplorable environmental and sanitary conditions.


2018 ◽  
Vol 55 (2) ◽  
pp. 165-171.e1 ◽  
Author(s):  
Simon G. Rodier ◽  
Charles J. DiMaggio ◽  
Stephen Wall ◽  
Vasiliy Sim ◽  
Spiros G. Frangos ◽  
...  

2020 ◽  
Vol 44 ◽  
Author(s):  

Confirmed cases in Australia notified up to 10 May 2020: notifications = 6,971; deaths = 98. The incidence of new cases of COVID-19 has reduced dramatically since a peak in mid-march. The reduction in international travel, social distancing measures and public health action have likely been effective in slowing the spread of the disease, in the Australian community. Cases of COVID-19 continue to be notified by jurisdictions, albeit at a slowed rate. Testing rates over the past week have increased markedly, with a very low proportion of people testing positive. These low rates of detection are indicative of low levels of COVID-19 transmission. It is important that testing rates and community adherence to public health measures remain high to support the continued suppression of the virus, particularly in vulnerable high-risk groups and settings. In the past reporting week new cases in Australia are mostly considered to be locally acquired, consistent with the drop in international travel. Most locally-acquired cases can be linked back to a known case or cluster. Although the proportion of locally-acquired cases has increased, the overall rate of cases, regardless of place of acquisition, continues to decrease. The crude case fatality rate in Australia remains low (1.4%), compared with the WHO reported global rate (6.9%). The low case fatality rate is likely reflective of high case detection and high quality of health care services in Australia. Deaths from COVID-19 in Australia have occurred predominantly among the elderly and those with comorbidities, with no deaths occurring in those under 40 years. The highest rate of COVID-19 continues to be among people aged 60-79 years, with a third of these cases associated with several outbreaks linked to cruise ships. The lowest rate of disease is in young children, a pattern reflected in international reports. Internationally, cases continue to increase, with some areas such as Brazil and India showing a dramatic rise in reported cases. Although some low-income countries have currently reported few cases, it is possible that this is due to limited diagnostic and public health capacity, and may not be reflective of disease occurrence.


2020 ◽  
Vol 22 (2) ◽  
pp. 117-128 ◽  
Author(s):  
Shivam Gupta ◽  
Kamalesh Kumar Patel ◽  
Shobana Sivaraman ◽  
Abha Mangal

As the COVID-19 pandemic marches exponentially, epidemiological data is of high importance to analyse the current situation and guide intervention strategies. This study analyses the epidemiological data of COVID-19 from 17 countries, representing 85 per cent of the total cases within first 90 days of lockdown in Wuhan, China. It follows a population-level observational study design and includes countries with 20,000 cases (or higher) as of 21 April 2020. We sourced the data for these 17 countries from worldometers. info, a digital platform being used by several media and reputed academic institutions worldwide. We calculated the prevalence, incidence, case fatality rate and trends in the epidemiology of COVID-19, and its correlation with population density, urbanisation and elderly population. The analysis represents 85 per cent ( N = 2,183,661) of all cases within the first 90 days of the pandemic. Across the analysed period, the burden of the pandemic primarily focused on high- and middle-income countries of Asia, Europe and North America. While the total number of cases and deaths are highest in USA, the prevalence, incidence and case fatality rates are higher in the European countries. The prevalence and incidence vary widely among countries included in the analysis, and the number of cases per million and the case fatality rate are correlated with the proportion of the elderly population and to a lesser extent with the proportion of the urban population.


2021 ◽  
pp. 12-14
Author(s):  
Kamlesh Sharma ◽  
Ram Lal Sharma

COVID-19 is a emerging disease and is of public health importance.This study was done to analyse the trends of corona pandemic over a period of one year in Himalayan region in India. Data regarding state statistics from January 2020 to January 2021,was gathered from various sources. Since objective and authentic data was released by different agencies daily and reported to WHO, so the state prole of new cases, cumulative cases, recoveries, cumulative deaths, samples tested, positive samples was taken based on availability of information from National Health Mission site, other state websites and news papers and analysed for various parameters. The current study conducted in Himachal Pradesh showed Case fatality rate as 1.7%, recovery rate 99% and positivity rate 6.1% with Shimla having highest CFR 2.5%. Population wise most affected district was Lahul & Spiti with affected population 4.0%.It may be considered as a severe public health threat of this decade. COVID-19 trends, pattern and its analysis will be very important for control and preventive measures.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Rapeepong Suphanchaimat ◽  
Vorasith Sornsrivichai ◽  
Supon Limwattananon ◽  
Panithee Thammawijaya

Abstract Background Road traffic injuries (RTIs) have been one of the most critical public health problems in Thailand for decades. The objective of this study was to examine to what extent provincial economy was associated with RTIs, road traffic deaths and case fatality rate in Thailand. Methods A secondary data analysis on time-series data was applied. The unit of analysis was a panel of 77 provinces during 2012–2016. Data were obtained from relevant public authorities, including the Ministry of Public Health. Descriptive statistics and econometric models, using negative binomial (NB) regression, negative binomial regression with random-effects (RE) model, and spatial Durbin model (SDM) were employed. The main predictor variable was gross domestic product (GDP) per capita and the outcome variables were incidence proportion of RTIs, traffic deaths and case fatality rate. The analysis was adjusted for key covariates. Results The incidence proportion of RTIs rose from 449.0 to 524.9 cases per 100,000 population from 2012 till 2016, whereas the incidence of traffic fatalities fluctuated between 29.7 and 33.2 deaths per 100,000 population. Case fatality rate steadily stood at 0.06–0.07 deaths per victim. RTIs and traffic deaths appeared to be positively correlated with provincial economy in the NB regression and the RE model. In the SDM, a log-Baht increase in GDP per capita (equivalent to a growth of GDP per capita by about 2.7 times) enlarged the incidence proportion of injuries and deaths by about a quarter (23.8–30.7%) with statistical significance. No statistical significance was found in case fatality rate by the SDM. The SDM also presented the best model fitness relative to other models. Conclusion The incidence proportion of traffic injuries and deaths appeared to rise alongside provincial prosperity. This means that RTIs-preventive measures should be more intensified in economically well-off areas. Furthermore, entrepreneurs and business sectors that gain economic benefit in a particular province should share responsibility in RTIs prevention in the area where their businesses are running. Further studies that explore others determinants of road safety, such as patterns of vehicles used, attitudes and knowledge of motorists, investment in safety measures, and compliance with traffic laws, are recommended.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Clement Ameh Yaro ◽  
Ezekiel Kogi ◽  
Kenneth Nnamdi Opara ◽  
Gaber El-Saber Batiha ◽  
Roua S. Baty ◽  
...  

Abstract Background Lassa fever (LF) is a zoonotic infectious disease of public concern in Nigeria. The infection dynamics of the disease is not well elucidated in Nigeria. This study was carried out to describe the pattern of infection, case fatality rate and spread of lassa virus (LASV) from 2017 to 2020. Methods Weekly epidemiological data on LF from December, 2016 to September, 2020 were obtained from Nigeria Centre for Disease Control. The number of confirmed cases and deaths were computed according to months and states. Descriptive statistics was performed and case fatality rate was calculated. Distribution and spread maps of LF over the four years period was performed on ArcMap 10.7. Results A total of 2787 confirmed cases and 516 deaths were reported in Nigeria from December, 2016 to September, 2020. Increase in number of cases and deaths were observed with 298, 528, 796 and 1165 confirmed cases and 79, 125, 158 and 158 deaths in 2017, 2018, 2019 and 2020 respectively. Over 60% of the cases were reported in two states, Edo and Ondo states. The LF cases spread from 19 states in 2017 to 32 states and Federal Capital Territory (FCT) in 2020. Ondo state (25.39%) had the highest of deaths rate from LF over the four years. Case fatality rate (CFR) of LF was highest in 2017 (26.5%) with CFR of 23.7, 19.6 and 13.4% in 2018, 2019 and 2020 respectively. The peak of infection was in the month of February for the four years. Infections increases at the onset of dry season in November and decline till April when the wet season sets-in. Conclusion There is an annual increase in the number of LASV infection across the states in Nigeria. There is need to heighten control strategies through the use of integrated approach, ranging from vector control, health education and early diagnosis.


Author(s):  
Paolo Pasquariello ◽  
Saverio Stranges

There is much discussion among clinicians, epidemiologists, and public health experts about why case fatality rate from COVID-19 in Italy (at 13.3% as of April 20, 2020, versus a global case fatality rate of 6.9%) is considerably higher than estimates from other countries (especially China, South Korea, and Germany). In this article, we propose several potential explanations for these differences. We suggest that Italy’s overall and relative case fatality rate, as reported by public health authorities, is likely to be inflated by such factors as heterogeneous reporting of coronavirus-related fatalities across countries and the iceberg effect of under-testing, yielding a distorted view of the global severity of the COVID-19 pandemic. We also acknowledge that deaths from COVID-19 in Italy are still likely to be higher than in other equally affected nations due to its unique demographic and socio-economic profile. Lastly, we discuss the important role of the stress imparted by the epidemic on the Italian healthcare system, which weakened its capacity to adequately respond to the sudden influx of COVID-19 patients in the most affected areas of the country, especially in the Lombardy region.


2021 ◽  
Author(s):  
Hai-Zhen Chen ◽  
Bo Cai ◽  
Jian-Guo Chen

Abstract Background: The novel coronavirus pneumonia (COVID-19) has been global threaten to public health. This paper provides perspective to the decision-making for public health control of the pandemic or the spread of epidemic.Methods: According to the WHO global reported database, we developed and used the number of cumulative cases, and the number of cumulative deaths to calculate and analyze rates of incidence, mortality, and fatality by country, with respect to the 30 highest outbreak (Top 30) countries.Results: As of December 31, 2020, of the global population of 7.585 billion, the cumulative number of reported cases was 81,475,053, and the cumulative number of deaths was 1,798,050. The incidence rate of COVID-19 was 1074.13 per 100,000 population, the mortality rate was 23.70 per 100,000, and the case fatality rate was 2.21%. Among the Top 30 countries, the five countries with the highest number of reported cumulative cases were, in rank, the United States (19,346,790 cases), India (10,266,674), Brazil (7,563,551), Russia (3,159,297) and France (2,556,708), and the five countries with the highest number of cumulative deaths were the United States (335,789 cases), Brazil (192,681), India (148,738), Mexico (123,845) and Italy (73,604). Globally, the countries with the highest incidence rate were, in rank, Andorra, Luxembourg, Montenegro, San Marino, and Czechia; the countries with the highest mortality rate were, in rank, San Marino, Belgium, Slovenia, Italy, and North Macedonia. The highest fatality rate was found in Yemen, Mexico, Montserrat, Isle of Man, and Ecuador, respectively. In China, 96,673 cases of COVID-19 and 4788 deaths were reported in 2020, ranking the 78th and the 43rd, respectively, in the world. The incidence rate and mortality rate were 6.90/105 and 0.34/105, respectively, ranking 207th and 188th in the world. The case fatality rate was 4.95%, ranking 11th in the world.Conclusions: The COVID-19 prevalence is still on the rise, and the turning points of incidence and mortality are not yet forecasted. Personal protection, anti-epidemic measures and efforts from public health personnel, medical professionals, biotechnology R&D personnel, effectiveness of the vaccination programs and the governments, are the important factors to determine the future prevalence of this coronavirus disease.


Author(s):  
Ibrahim S. Baffa ◽  
Yahaya Mohammed ◽  
Rabi Usman ◽  
Aisha Abubakar ◽  
Patrick Nguku

ObjectiveWe reviewed measles specific Integretaged Disease Surveillance and Response (IDSR) data from Nigeria over a five-year period to highlights its burden and trends, and make recommendations for improvements.IntroductionMeasles is a vaccine preventable, highly transmissible viral infection that affects mostly under-five year children. The disease is caused by a Morbillivirus; member of the Paramyxovirus family.MethodsWe conducted a secondary data analysis of measles specific IDSR records of all States in Nigeria from January 2012 to September 2016. The record had reported measles cases with laboratory outcomes from all the States. IDSR weekly epidemiological data were obtained from Surveillance Unit, Nigerian Centre for Disease Control (NCDC).ResultsA total of 131,732 cases were recorded within the period. Highest number of cases 57,892(43.95%) were recorded in 2013 while the least number of cases 11,061(8.4%) were recorded in 2012. A total of 817 deaths were recorded, given a case fatality rate (CFR) of 0.62%. The CFR showed a decreasing trend over the years with the highest CFR (1.43%) recorded in 2012 and the least CFR (0.44%) recorded in 2016. Only 8,916 (6.7%) cases were confirmed by laboratory investigation. The Northwest region recorded the highest attack rate (AR) of 149.7 cases per 100,000 population, followed by the Northeast region with 140.2 cases per 100,000 population, while the South-south region recorded the least AR of 15.8 cases per 100,000 population. Case Fatality Rate per region followed similar pattern, with the Northcentral region having the highest CFR of 4.38%. The trend of measles cases followed the same pattern. Cases peaked at March, then gradually reduced to lowest level at June.ConclusionsMeasles infection remains a burden especially in the northern region of Nigeria. Though measles fatalities were on decline over the years, laboratory diagnosis of cases has been suboptimal. We recommended improvement on routine immunization and measles case management, and strengthening of regional laboratories capacity for measles diagnosis.References1. WHO | Measles. WHO [Internet]. World Health Organization; 2017 [cited 2017 Apr 10]; Available from: http://www.who.int/mediacentre/factsheets/fs286/en/2. Akande TM. A review of measles vaccine failure in developing countries. Niger. Med. Pract. SAME Ventures; 2007;52:112–6.3. Ibrahim BS, Gana GJ, Mohammed Y, Bajoga UA, Olufemi AA, Umar AS, et al. Outbreak of measles in Sokoto State North-Western Nigeria, three months after a supplementary immunization campaign: An investigation report 2016. Australas. Med. J. AUSTRALASIAN MEDICAL JOURNAL PTY LTD HILLARYS, GPO BOX 367, PERTH, WA 6923, AUSTRALIA; 2016;9:324–35. 


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