scholarly journals The relationship between affective visual mismatch negativity to interpersonal difficulties across autism and schizotypal traits

2021 ◽  
Author(s):  
Talitha C. Ford ◽  
Laila E. Hugrass ◽  
Bradley N. Jack
Keyword(s):  
Auditory Processing ◽  
Mismatch Negativity ◽  
Autism Spectrum ◽  
Autism Spectrum Quotient ◽  
Schizophrenia Spectrum Disorders ◽  
Schizotypal Personality ◽  
Schizophrenia Spectrum ◽  
Interpersonal Difficulties ◽  
Spectrum Disorders ◽  
The Relationship

AbstractSensory deficits are a feature of autism and schizophrenia spectrum disorders and are also common at the upper end of their non-clinical spectra. The mismatch negativity (MMN), an index of preattentive auditory processing, is particularly sensitive in detecting such deficits; however, little is known about the relationship between the visual MMN (vMMN) to emotional faces and the specific traits that exist within the spectrum disorders. We probed the vMMN to happy, sad, and neutral faces in 77 young adults (18-40 years) and found that the vMMN to happy faces (happy standard minus happy deviant stimuli) was significantly larger than the vMMNs to sad and neutral faces (p > 0.05). We also found a significant correlation between vMMN to happy faces and interpersonal difficulties as indexed by the Autism Spectrum Quotient (AQ) Communication and Attention to Detail subscales, and Schizotypal Personality Questionnaire (SPQ) Interpersonal Features (p < 0.05). These findings suggest a specificity of preattentive processing of positive affect to interpersonal features across the autism and schizophrenia spectrum.

The Relationship Between Multisensory Temporal Processing and Schizotypal Traits

2020 ◽  
Author(s):  
Tyler C. Dalal ◽  
Anne-Marie Muller ◽  
Ryan A Stevenson
Keyword(s):  
Temporal Processing ◽  
Temporal Order Judgment ◽  
Judgment Task ◽  
Schizophrenia Spectrum Disorders ◽  
Magical Thinking ◽  
Schizotypal Personality ◽  
Schizophrenia Spectrum ◽  
Schizotypal Personality Questionnaire ◽  
Spectrum Disorders ◽  
The Relationship

Recent literature has suggested that atypical sensory processing observed in schizophrenia may contribute to clinical symptomatology. Specifically, multisensory temporal processing was shown to be strongly associated with hallucination severity. Here, we explored whether this relationship extends to a broader spectrum of schizotypal traits, in line with the DSM-5’s shift towards a more dimensional approach to diagnostic criteria within Schizophrenia Spectrum Disorders. Fifty-one participants completed an audiovisual temporal order judgment task as a measure of multisensory temporal processing and self-reported levels of schizotypal traits using the Schizotypal Personality Questionnaire. These data revealed two novel findings. First, less precise multisensory temporal processing was related to higher overall levels of schizotypal traits. Second, this relationship was specific to the cognitive-perceptual domain, and more specifically, the Unusual Perceptual Experiences and Odd Beliefs or Magical Thinking measures. Previous literature has shown that less precise multisensory temporal processing was related to the severity of hallucinations in schizophrenia. These findings provide a novel, direct extension of this previous work by demonstrating that this relationship applies to traits across the schizophrenia spectrum, including at the subclinical level.

scholarly journals Mediating effects of self-stigma and depression on the association between autistic symptoms and recovery in patients with schizophrenia-spectrum disorders: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hiroshi Komatsu ◽  
Takashi Ono ◽  
Goh Onoguchi ◽  
Hiroaki Tomita ◽  
Yoshihisa Kakuto
Keyword(s):  
Depressive Symptoms ◽  
Autism Spectrum ◽  
Equation Modeling ◽  
Autism Spectrum Quotient ◽  
Schizophrenia Spectrum Disorders ◽  
Schizophrenia Spectrum ◽  
Stereotype Endorsement ◽  
Negative Effect ◽  
Autistic Symptoms ◽  
Spectrum Disorders

Abstract Background Several studies have indicated that self-stigma is associated with depressive symptoms and could be a barrier to recovery in patients with schizophrenia-spectrum disorders. More recently, an association between autistic symptoms and self-stigma was found in schizophrenia-spectrum patients. This study aimed to investigate the association between self-stigma, autistic and depressive symptoms, and recovery in patients with schizophrenia. Methods In total, 105 participants were evaluated using the Autism Spectrum Quotient, the Internalized Stigma of Mental Illness Scale, the Quick Inventory of Depressive Symptomatology, and the Recovery Assessment Scale to investigate autistic symptoms, self-stigma, depressive symptoms, and recovery, respectively. The relationship between self-stigma, autistic symptoms, depressive symptoms, and recovery was assessed using structural equation modeling analysis. Results Impaired attention switching, one symptom of autism, was found to positively affect stereotype endorsement, which negatively influenced recovery through depressive symptoms. Moreover, problems with communication skills negatively affected recovery through depressive symptoms. Concerning self-stigma, stereotype endorsement and perceived discrimination had a negative effect on recovery through depressive symptoms, whereas stigma resistance had a direct negative effect on recovery. Conclusions This study may provide meaningful insight into the psychological structure of recovery and could inform effective interventions for patients with schizophrenia-spectrum disorders. This was a cross-sectionally designed study; therefore, further longitudinal studies are needed to identify the causal relationships between self-stigma, autistic and depressive symptoms, and recovery.

The Relationship Between Multisensory Temporal Processing and Schizotypal Traits

2021 ◽  
pp. 1-19
Author(s):  
Tyler C. Dalal ◽  
Anne-Marie Muller ◽  
Ryan A. Stevenson
Keyword(s):  
Sensory Processing ◽  
Temporal Processing ◽  
Recent Literature ◽  
Clinical Sample ◽  
Schizophrenia Spectrum Disorders ◽  
Magical Thinking ◽  
Schizotypal Personality ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders ◽  
The Relationship

Abstract Recent literature has suggested that deficits in sensory processing are associated with schizophrenia (SCZ), and more specifically hallucination severity. The DSM-5’s shift towards a dimensional approach to diagnostic criteria has led to SCZ and schizotypal personality disorder (SPD) being classified as schizophrenia spectrum disorders. With SCZ and SPD overlapping in aetiology and symptomatology, such as sensory abnormalities, it is important to investigate whether these deficits commonly reported in SCZ extend to non-clinical expressions of SPD. In this study, we investigated whether levels of SPD traits were related to audiovisual multisensory temporal processing in a non-clinical sample, revealing two novel findings. First, less precise multisensory temporal processing was related to higher overall levels of SPD symptomatology. Second, this relationship was specific to the cognitive–perceptual domain of SPD symptomatology, and more specifically, the Unusual Perceptual Experiences and Odd Beliefs or Magical Thinking symptomatology. The current study provides an initial look at the relationship between multisensory temporal processing and schizotypal traits. Additionally, it builds on the previous literature by suggesting that less precise multisensory temporal processing is not exclusive to SCZ but may also be related to non-clinical expressions of schizotypal traits in the general population.

Sleep and cognition in schizophrenia spectrum disorders: A systematic review protocol.

2020 ◽  
Author(s):  
Sean Carruthers ◽  
Gemma Brunetti ◽  
Susan Rossell
Keyword(s):  
Systematic Review ◽  
Mental Illnesses ◽  
Schizophrenia Spectrum Disorders ◽  
Systematic Review Protocol ◽  
Schizophrenia Spectrum Disorder ◽  
Schizophrenia Spectrum ◽  
Review Protocol ◽  
Spectrum Disorders ◽  
Sleep And Cognition ◽  
The Relationship

Schizophrenia spectrum disorders are chronic and debilitating mental illnesses characterised by both cognitive impairments and sleep deficits. In this systematic review protocol, we outline an approach to examine the available literature investigating the relationship between sleep and cognition in individuals with schizophrenia spectrum disorder.

scholarly journals The impact of schizotypy on pragmatics

2020 ◽  
Vol 62 ◽  
pp. e020014
Author(s):  
Monica de Freitas Frias Chaves ◽  
Cilene Rodrigues
Keyword(s):  
Personality Traits ◽  
Contextual Information ◽  
Brazilian Portuguese ◽  
Schizophrenia Spectrum Disorders ◽  
Semantic Meaning ◽  
General Hypothesis ◽  
Schizotypal Personality ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders ◽  
The Impact

High levels of linguistic referential failures are associated with liability to develop schizophrenia-spectrum disorders, and it has been shown that these failures can differentiate healthy subjects, high-schizotypal and schizophrenics groups. Nevertheless, few investigations have focused on whether or not schizotypal traits in nonclinical populations can also impact linguistic reference. In Brazilian Portuguese, only one previous study (acceptability judgements task) had been conducted, and its results suggest association between schizotypal traits and a more rigid preference for assignment of specific readings to definite singular DPs. Here, we present another experimental study in Brazilian Portuguese,  a comprehension task designed to examine possible effects of schizotypal personality traits on the interpretation of definite singular DPs. The findings, in line with the previous results, support the conclusion that schizotypy does affect the interpretation of definite singular DPs in Brazilian Portuguese. Together, these two experiments suggest that schizotypal personality traits impact the integration of linguistic contextual information into the semantic meaning of definite DPs. This is  consistent with the general hypothesis that schizotypy, similarly to schizophrenia, is associated with pragmatic difficulties. Yet, our results emphasize that the impact of schizotypal traits on pragmatics can be observed even in healthy (nonclinical) speakers.

Variable Insight in OCD

2017 ◽  
Author(s):  
Rebecca J. Hamblin ◽  
Jennifer Moonjung Park ◽  
Monica S. Wu ◽  
Eric A. Storch
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Assessment Tools ◽  
Schizophrenia Spectrum Disorders ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders ◽  
Definition Of ◽  
The Relationship ◽  
Insight Into

Individuals with obsessive-compulsive disorder (OCD) often have good insight into the irrational nature of their obsessions and the excessive character of their compulsions, but insight exists along a continuum and is markedly poor in some patients. This chapter reviews the assessment and phenomenological correlates of variable insight in OCD in both pediatric and adult populations. It reviews the definition of insight and its relationship to the evolution of diagnostic criteria for obsessive-compulsive disorder, as well as the major assessment tools used to measure and quantify insight for clinical and research purposes. The relationships between insight and clinical characteristics of OCD, including symptom severity, comorbidity, and treatment response are reviewed, followed by a review of neurobiological correlates of insight and the relationship between poor insight and schizophrenia spectrum disorders.

scholarly journals A review of autobiographical memory studies on patients with schizophrenia spectrum disorders

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Yujia Zhang ◽  
Sara K. Kuhn ◽  
Laura Jobson ◽  
Shamsul Haque
Keyword(s):  
Autobiographical Memory ◽  
Psychotic Symptoms ◽  
Control Group ◽  
Schizophrenia Spectrum Disorders ◽  
Autobiographical Memories ◽  
Memory Specificity ◽  
Autobiographical Memory Specificity ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders ◽  
The Relationship

Abstract Background Patients suffering from schizophrenia spectrum disorders demonstrate various cognitive deficiencies, the most pertinent one being impairment in autobiographical memory. This paper reviews quantitative research investigating deficits in the content, and characteristics, of autobiographical memories in individuals with schizophrenia. It also examines if the method used to activate autobiographical memories influenced the results and which theoretical accounts were proposed to explain the defective recall of autobiographical memories in patients with schizophrenia. Methods PsycINFO, Web of Science, and PubMed databases were searched for articles published between January 1998 and December 2018. Fifty-seven studies met the inclusion criteria. All studies implemented the generative retrieval strategy by inducing memories through cue words or pictures, the life-stage method, or open-ended retrieval method. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement guidelines were followed for this review. Results Most studies reported that patients with schizophrenia retrieve less specific autobiographical memories when compared to a healthy control group, while only three studies indicated that both groups performed similarly on memory specificity. Patients with schizophrenia also exhibited earlier reminiscence bumps than those for healthy controls. The relationship between comorbid depression and autobiographical memory specificity appeared to be independent because patients’ memory specificity improved through intervention, but their level of depression remained unchanged. The U-shaped retrieval pattern for memory specificity was not consistent. Both the connection between the history of attempted suicide and autobiographical memory specificity, and the relationship between psychotic symptoms and autobiographical memory specificity, remain inconclusive. Patients’ memory specificity and coherence improved through cognitive training. Conclusions The overgeneral recall of autobiographical memory by patients with schizophrenia could be attributed to working memory, the disturbing concept of self, and the cuing method implemented. The earlier reminiscence bump for patients with schizophrenia may be explained by the premature closure of the identity formation process due to the emergence of psychotic symptoms during early adulthood. Protocol developed for this review was registered in PROSPERO (registration no: CRD42017062643).

Cognitive and Prepulse Inhibition Deficits in Psychometrically High Schizotypal Subjects in the General Population: Relevance to Schizophrenia Research

2012 ◽  
Vol 18 (4) ◽  
pp. 643-656 ◽  
Author(s):  
Stella G. Giakoumaki
Keyword(s):  
Cognitive Function ◽  
General Population ◽  
Prepulse Inhibition ◽  
Future Research ◽  
Attention And Memory ◽  
Schizophrenia Spectrum Disorders ◽  
Schizotypal Personality ◽  
Psychosis Proneness ◽  
Schizophrenia Spectrum ◽  
The Relationship

AbstractSchizophrenia and schizotypal personality disorder share common clinical profiles, neurobiological and genetic substrates along with Prepulse Inhibition and cognitive deficits; among those, executive, attention, and memory dysfunctions are more consistent. Schizotypy is considered to be a non-specific “psychosis-proneness,” and understanding the relationship between schizotypal traits and cognitive function in the general population is a promising approach for endophenotypic research in schizophrenia spectrum disorders. In this review, findings for executive function, attention, memory, and Prepulse Inhibition impairments in psychometrically defined schizotypal subjects have been summarized and compared to schizophrenia patients and their unaffected first-degree relatives. Cognitive flexibility, sustained attention, working memory, and Prepulse Inhibition impairments were consistently reported in high schizotypal subjects in accordance to schizophrenia patients. Genetic studies assessing the effects of various candidate gene polymorphisms in schizotypal traits and cognitive function are promising, further supporting a polygenic mode of inheritance. The implications of the findings, methodological issues, and suggestions for future research are discussed. (JINS, 2012, 18, 1–14)

scholarly journals Re-directing Climate Change and Terrorism by Allying Classical with Quantum Neural Computing

2017 ◽  
Vol 5 (6) ◽  
pp. 94
Author(s):  
Antonio Cassella
Keyword(s):  
Climate Change ◽  
Autism Spectrum ◽  
Shared Knowledge ◽  
Schizophrenia Spectrum Disorders ◽  
Neural Computing ◽  
Shared Beliefs ◽  
Quantum Capacity ◽  
Schizophrenia Spectrum ◽  
The Social ◽  
Spectrum Disorders

Before the turn of the 21st century, terrorism and climate change may cause the breakdown of civilization. The cause of this advancing upheaval is the disparity between scientific ascent and social descent. This paper explores the social values hidden in sacred texts and artistic masterpieces through a debatable view of an impaired capacity for renewing familiar reality in Autism Spectrum Disorder (ASD), as well as an impaired ability to preserve shared beliefs in Schizophrenia Spectrum Disorders (SSD). The author posits that we will overcome the challenges unleashed by fundamentalism and global warming if we bolster the alliance of a) our quantum capacity for renovating shared knowledge with our classical ability to preserve it and of b) our appreciation of beauty with a humanistic use of science.

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